阅读说明：本技术 X射线平板探测器的多帧叠加成像方法 (Multi-frame superposition imaging method of X-ray flat panel detector ) 是由 范奇威 马扬喜 李煦 张楠 于 2020-12-30 设计创作，主要内容包括：本发明提供一种X射线平板探测器的多帧叠加成像方法,包括步骤：提供X射线平板探测器,该探测器包括X射线发生装置及成像装置,成像装置包括N个可在X射线到达N个不同的剂量阈值时对应成像的可成像组织,N为大于等于2的整数；X射线发生装置朝被成像物连续发射出X射线,在X射线剂量到达每一阈值的过程中及到达每一阈值时,可在对应的阈值下成像的可成像组织连续采集多帧图像；对采集的多帧图像进行图像处理以及校正以得到所需图像。本发明可以最少的剂量实现成像效果最大化的目标,从而减少拍摄次数,降低拍摄剂量,让一次临床拍摄呈现出最全面最有价值的信息,能够极大地减少患者所吸收的剂量。(The invention provides a multi-frame superposition imaging method of an X-ray flat panel detector, which comprises the following steps: providing an X-ray flat panel detector, wherein the detector comprises an X-ray generating device and an imaging device, the imaging device comprises N imageable tissues which can be correspondingly imaged when the X-ray reaches N different dose thresholds, and N is an integer greater than or equal to 2; the X-ray generating device continuously emits X-rays towards the imaged object, and in the process that the X-ray dose reaches each threshold value and when the X-ray dose reaches each threshold value, the imageable tissues which can be imaged under the corresponding threshold values continuously acquire multi-frame images; and carrying out image processing and correction on the acquired multi-frame images to obtain a required image. The invention can realize the aim of maximizing the imaging effect with the least dose, thereby reducing the shooting times, reducing the shooting dose, presenting the most comprehensive and valuable information by one-time clinical shooting and greatly reducing the dose absorbed by a patient.)

1. A multi-frame superposition imaging method of an X-ray flat panel detector is characterized by comprising the following steps:

providing an X-ray flat panel detector, wherein the X-ray flat panel detector comprises an X-ray generating device and an imaging device, the imaging device comprises N imageable tissues which can be correspondingly imaged when X-rays reach N different dose thresholds, and N is an integer greater than or equal to 2;

the X-ray generating device continuously emits X-rays towards the imaged object, and multi-frame images can be continuously acquired by the imageable tissues imaged under the corresponding threshold values in the process that the X-ray dose reaches each threshold value and when the X-ray dose reaches each threshold value;

and carrying out image processing and correction on the acquired multi-frame images to obtain a required image.

2. The multi-frame superposition imaging method according to claim 1, wherein said correction comprises a background correction and a gain correction.

3. The multi-frame superposition imaging method according to claim 1, wherein the number of acquisition frames for different threshold intervals is different.

4. A multi-frame overlay imaging method according to any one of claims 1-3, wherein the imaging device comprises low-dose imageable tissue that is imageable when the X-ray dose reaches a first threshold, other-dose imageable tissue that is imageable when the X-ray dose reaches a second threshold, and high-dose imageable tissue that is imageable when the X-ray dose reaches a third threshold, the first threshold < the second threshold < the third threshold.

5. The multi-frame superposition imaging method according to claim 4, wherein the imaged object is a human body, the front of the chest of the human body is imaged when a first threshold is reached, the abdomen of the human body is imaged when a second threshold is reached, and the lumbar of the human body is imaged when a third threshold is reached.

6. A control module, comprising a memory and a processor;

the memory is used for storing a computer program;

the processor is configured to execute the memory-stored computer program to cause the control module to perform the multi-frame superposition imaging method according to any of claims 1-5.

7. A storage medium having stored thereon a computer program, wherein the computer program, when executed by a processor, implements the multi-frame superposition imaging method according to any one of claims 1 to 5.

Technical Field

The invention relates to the field of imaging of an X-ray flat panel detector, in particular to a multi-frame superposition imaging method of the X-ray flat panel detector, a control module and a storage medium.

Background

The clinical medical X-ray shooting imaging can be only shot under a fixed dosage, the imaging part is limited, the high dosage is only suitable for shooting high-density body tissues, and the low dosage is only suitable for shooting low-density body tissues. That is, in the prior art, the fixed dose is only used for imaging a part or tissue of a body part, and tissues with different densities cannot be imaged together. For example, fig. 1 and 2 are imaging diagrams of the same human body part under different X-ray doses, when a predetermined high dose is reached, the structure and distribution of the spine and femur in fig. 1 can be clearly seen, but the rib, tibia and coccyx (the circled marked part in fig. 1) belong to the exposed part, so that specific tissue structures cannot be presented; at a dose prior to reaching the predetermined high dose, the coccyx and tibia of fig. 2 are visible, but the femoral and vertebral portions (circled in fig. 2) do not penetrate and image well due to the insufficient dose. Therefore, in the prior art, when imaging parts of the same imaging object with different densities, for example, tissues of bones, muscles and the like with different densities need to be imaged repeatedly by adopting different dosages, so that the diagnosis cost is increased, and the patient is possibly harmed to the health of the human body due to long-time exposure to the X-ray environment.

Disclosure of Invention

In view of the above drawbacks of the prior art, an object of the present invention is to provide a multi-frame superposition imaging method for an X-ray flat panel detector, which is used to solve the problems that when imaging portions of the same imaging object with different densities, for example, when imaging tissues of different densities such as bones and muscles of a human body, different doses are required to be respectively adopted for repeated imaging for multiple times, so that not only is the diagnosis cost increased, but also the patient is exposed to an X-ray environment for a long time, which may cause harm to the health of the human body.

In order to achieve the above and other related objects, the present invention provides a multi-frame superposition imaging method for an X-ray flat panel detector, including the steps of:

providing an X-ray flat panel detector, wherein the X-ray flat panel detector comprises an X-ray generating device and an imaging device, the imaging device comprises N imageable tissues which can be correspondingly imaged when X-rays reach N different dose thresholds, and N is an integer greater than or equal to 2;

the X-ray generating device continuously emits X-rays towards the imaged object, and multi-frame images can be continuously acquired by imageable tissues which can be imaged under the threshold value in the process that the X-ray dose reaches each threshold value and when the X-ray dose reaches each threshold value;

and carrying out image processing and correction on the acquired multi-frame images to obtain a required image.

Optionally, the correction comprises a background correction and a gain correction.

Optionally, the number of acquisition frames of different threshold intervals is different.

Optionally, the imaging device comprises a low-dose imageable tissue that is imageable when the X-ray dose reaches a first threshold, a further-dose imageable tissue that is imageable when the X-ray dose reaches a second threshold, and a high-dose imageable tissue that is imageable when the X-ray dose reaches a third threshold, the first threshold < the second threshold < the third threshold.

Optionally, the imaged object is a human body, the front of the chest of the human body is imaged when reaching the first threshold, the abdomen of the human body is imaged when reaching the second threshold, and the lumbar of the human body is imaged when reaching the third threshold.

The invention also provides a control module, which comprises a processor and a memory; the memory is used for storing a computer program; the processor is configured to execute the computer program stored in the memory to cause the control module to execute the multi-frame superposition imaging method according to any one of the above aspects.

The present invention also provides a storage medium having a computer program stored thereon, wherein the computer program is executed by a processor to implement the multi-frame superposition imaging method according to any one of the above aspects.

As described above, the multi-frame superposition imaging method of the X-ray flat panel detector of the present invention has the following beneficial effects: the invention can realize the aim of maximizing the imaging effect with the least dose through the optimized flow design, is beneficial to reducing the shooting times and the shooting dose, and enables one-time clinical shooting to present the most comprehensive and valuable information. For example, when the device is used for disease diagnosis and treatment of a patient, information of different parts which can be presented under all different dosages can be collected through one-time shooting, the problem that various overexposure or incomplete information acquisition caused by insufficient dosage cannot occur, multiple times of dosage adjustment and repeated shooting work of shooting personnel are not needed to be carried out manually, and most importantly, the dosage absorbed by the patient can be greatly reduced.

Drawings

Fig. 1 and 2 show X-ray imaging diagrams of the same body part under different X-ray doses.

Fig. 3 is a schematic block diagram of the flat panel X-ray detector of the present invention.

Fig. 4 shows a schematic diagram of an image acquisition process of an example of the multi-frame superposition imaging method provided by the invention.

Description of the element reference numerals

11-an X-ray generating device; 12-scintillator layer and TFT panel layer; 13-an image processing module; 14-a correction module; 15-display module

Detailed Description

The following description of the embodiments of the present invention is provided for illustrative purposes, and other advantages and effects of the present invention will become apparent to those skilled in the art from the present disclosure.

Please refer to fig. 1 to 4. It should be understood that the structures, ratios, sizes, and the like shown in the drawings and described in the specification are only used for matching with the disclosure of the specification, so as to be understood and read by those skilled in the art, and are not used to limit the conditions under which the present invention can be implemented, so that the present invention has no technical significance, and any structural modification, ratio relationship change, or size adjustment should still fall within the scope of the present invention without affecting the efficacy and the achievable purpose of the present invention. In addition, the terms such as "upper", "lower", "left", "right", "middle" and "one" used in the present specification are for clarity of description, and are not intended to limit the scope of the present invention, and changes or modifications of the relative relationship may be made without substantial technical changes.

In the prior art, when imaging parts of the same imaging object with different densities, for example, when imaging the assembly of bones, muscles and the like of a human body with different densities, repeated imaging needs to be carried out by adopting different dosages respectively, so that the diagnosis cost is improved, and meanwhile, a patient is possibly harmed to the health of the human body due to long-time exposure to an X-ray environment. The invention therefore proposes an improvement.

Specifically, the invention provides a multi-frame superposition imaging method of an X-ray flat panel detector, which comprises the following steps:

providing an X-ray flat panel detector, wherein the X-ray flat panel detector comprises an X-ray generating device and an imaging device, the imaging device comprises N imageable tissues which can be correspondingly imaged when X-rays reach N different dose thresholds, and N is an integer greater than or equal to 2; if the X-ray flat panel detector is distinguished by functional modules, as shown in fig. 3, the X-ray flat panel detector can be roughly divided into an X-ray generating device 11 for emitting X-rays, a scintillator layer and a TFT panel layer 12 for converting the X-rays into electric signals, an image processing module 13 for converting the converted electric signals into images and amplifying the images, a correction module 14 for correcting the images, and a display module 15 for outputting the images, and the image acquisition process can be controlled by an FPGA, multi-frame acquisition can be performed in a single short-time exposure, and the display module can be controlled by an ARM;

the X-ray generating device continuously emits X-rays towards the imaged object, and multi-frame images can be continuously acquired by the imageable tissues imaged under the corresponding threshold values in the process that the X-ray dose reaches each threshold value and when the X-ray dose reaches each threshold value;

the acquired multi-frame images are subjected to image processing and correction to obtain a required image, wherein the image processing may be respectively processing the multi-frame images acquired by each imaging tissue (i.e. the images acquired by each imaging tissue are processed separately) and/or processing all the images acquired by all the imaging tissues (i.e. the images acquired by each imaging tissue are processed uniformly), and the correction is generally preferably performed on the images acquired by each imaging tissue separately.

The invention can realize the aim of maximizing the imaging effect with the least dose through the optimized flow design, is beneficial to reducing the shooting times and the shooting dose, and enables one-time clinical shooting to present the most comprehensive and valuable information. For example, when the device is used for disease diagnosis and treatment of a patient, information of different parts which can be presented under all different dosages can be collected through one-time shooting, the problem that various overexposure or incomplete information acquisition caused by insufficient dosage cannot occur, multiple times of dosage adjustment and repeated shooting work of shooting personnel are not needed to be carried out manually, and most importantly, the dosage absorbed by the patient can be greatly reduced. Of course, the present invention is not limited to medical diagnosis of human body, and may be used for other X-ray detection operations such as security inspection.

By way of example, the correction includes a background correction and a gain correction. Background correction is to collect a dark field image of an object to be imaged under the condition of no X-ray, and then subtract the dark field image from the image collected during X-ray exposure to remove background interference; the gain correction includes adjusting the amplification factor of the signal and/or adjusting the gray value. The imaging quality can be further improved by the correction.

In an example, the imaging device includes low-dose imageable tissue that is imageable when the X-ray dose reaches a first threshold, other-dose imageable tissue that is imageable when the X-ray dose reaches a second threshold, and high-dose imageable tissue that is imageable when the X-ray dose reaches a third threshold, the first threshold < the second threshold < the third threshold. In a further example, the imaged object is a human body, the front of the chest of the human body is imaged when a first threshold is reached, the abdomen of the human body is imaged when a second threshold is reached, and the lumbar of the human body is imaged when a third threshold is reached. For example, as shown in fig. 4, X-rays give a first threshold dose a (ugy) at which low-dose imageable tissue has reached an imageable dose condition (e.g., chest front), and X-frame images that have been continuously acquired until the first threshold a (ugy) dose is reached are superimposed; when the X-ray gives a second threshold dose b (ugy) at which other intermediate-dose imageable tissues have reached an imageable dose condition (such as the abdomen) and the Y frames of images that have been acquired continuously before the dose reached the second threshold b (ugy) are superimposed; when the X-ray gives a third threshold dosage C (uGy), the high-dose imageable tissue reaches the imageable dosage condition (such as lumbar), Z frame images which are continuously acquired before the dosage reaches the third threshold C (uGy) are superposed, a group of images can be formed by combining the images acquired by all dosages, and finally, a structural image which is in line with the expectation is selected for previewing. For example, still taking fig. 1 and 2 as an example, a clear image of a part to be previewed is selected from a plurality of images, at this time, the coccyx and tibia of fig. 1 can be clearly observed, but due to insufficient dose, the femur and vertebra parts (circled parts in fig. 1) cannot be well penetrated and imaged, and thus cannot be carefully observed and judged, but at this time, a preview image required by high dose in a map group can still be selected; the spine and femoral portions of fig. 2 are clearly visible in their structure and detail so that the combination provides a good preview of the overall anatomy or structure. In one example, the number of acquisition frames for different threshold intervals is different. For example, in the foregoing example, in the process of imaging the human body when the X-ray dose increases from zero to the first threshold a (ugy), the number of frames X acquired by the low-dose imageable tissue is less than the number of frames Y acquired by the other-dose imageable tissue in the interval from the first threshold a (ugy) to the second threshold b (ugy), and is also less than the number of frames Z acquired by the high-dose imageable tissue in the interval from the second threshold b (ugy) to the third threshold c (ugy), and the number of frames acquired by the other-dose imageable tissue is the largest, and each imaging tissue superimposes the corresponding acquired multiple frames of images. For example, in one example, X is 50 to 70, Y is 100 or more, and Z is 70 to 90. The other dosage imageable tissues are used for imaging the human abdomen, more important human organ tissues are distributed on the human abdomen, and the acquisition of images with more frames in the process is helpful for improving the accuracy of medical diagnosis. Of course, the number of frames of the images acquired in each threshold interval may be set according to the X-ray irradiation time, the tissue density of the portion to be imaged, different diagnosis needs, and the like, and is not strictly limited in this embodiment.

The invention also provides a control module, which comprises a processor and a memory; the memory is used for storing a computer program; the processor is configured to execute the computer program stored in the memory to cause the control module to execute the multi-frame superposition imaging method according to any one of the preceding aspects.

Specifically, the Processor may be a general-purpose Processor, and includes a Central Processing Unit (CPU), a Network Processor (NP), and the like; the device can also be a Digital Signal Processor (DSP), an Application Specific Integrated Circuit (ASIC), a Field Programmable Gate Array (FPGA) or other Programmable logic device, a discrete Gate or transistor logic device, or a discrete hardware component. The memory includes various media that can store program codes, such as ROM, RAM, magnetic disk, U-disk, memory card, or optical disk.

It should be noted that the division of each functional unit of the above modules is only a logical division, and the actual implementation may be wholly or partially integrated into one physical entity, or may be physically separated. And these units can be implemented entirely in software, invoked by a processing element; or may be implemented entirely in hardware; the method can also be realized partly in the form of calling software by the processing element and partly in the form of hardware. For example, the control module may be a processing element separately set up, or may be implemented by being integrated in a chip of the apparatus, or may be stored in a memory of the apparatus in the form of program code, and the function of the control module may be called and executed by a processing element of the apparatus. Other modules are implemented similarly. In addition, all or part of the modules can be integrated together or can be independently realized. The processing element described herein may be an integrated circuit having signal processing capabilities. In implementation, each step of the above method or each module above may be implemented by an integrated logic circuit of hardware in a processor element or an instruction in the form of software.

For example, the above modules may be one or more integrated circuits configured to implement the above methods, such as: one or more Application Specific Integrated Circuits (ASICs), or one or more microprocessors (DSPs), or one or more Field Programmable Gate Arrays (FPGAs), among others. For another example, when one of the above modules is implemented in the form of a Processing element scheduler code, the Processing element may be a general-purpose processor, such as a Central Processing Unit (CPU) or other processor capable of calling program code. For another example, these modules may be integrated together and implemented in the form of a system-on-a-chip (SOC).

The present invention also provides a storage medium having stored thereon a computer program which, when executed by a processor, implements a multi-frame superposition imaging method as described in any of the preceding aspects.

Specifically, the storage medium includes various media that can store program codes, such as ROM, RAM, a magnetic disk, a usb disk, a memory card, or an optical disk.

In summary, the present invention provides a multi-frame superimposed imaging method for an X-ray flat panel detector, where the multi-frame superimposed imaging method includes the steps of: providing an X-ray flat panel detector, wherein the X-ray flat panel detector comprises an X-ray generating device and an imaging device, the imaging device comprises N imageable tissues which can be correspondingly imaged when X-rays reach N different dose thresholds, and N is an integer greater than or equal to 2; the X-ray generating device continuously emits X-rays towards the imaged object, and multi-frame images can be continuously acquired by the imageable tissues which can be imaged under the corresponding threshold values in the process that the X-ray dose reaches each threshold value and when the X-ray dose reaches each threshold value; and carrying out image processing and correction on the acquired multi-frame images to obtain a required image. The invention can realize the aim of maximizing the imaging effect with the least dose through the optimized flow design, is beneficial to reducing the shooting times and the shooting dose, and enables one-time clinical shooting to present the most comprehensive and valuable information. For example, when the device is used for disease diagnosis and treatment of a patient, information of different parts which can be presented under all different dosages can be collected through one-time shooting, the problem that various overexposure or incomplete information acquisition caused by insufficient dosage cannot occur, multiple times of dosage adjustment and repeated shooting work of shooting personnel are not needed to be carried out manually, and most importantly, the dosage absorbed by the patient can be greatly reduced. The multi-frame superposition imaging method is particularly suitable for medical static detectors, particularly detectors with high frame rate functions, and can improve the dynamic range and expand the product application. Therefore, the invention effectively overcomes various defects in the prior art and has high industrial utilization value.

The foregoing embodiments are merely illustrative of the principles and utilities of the present invention and are not intended to limit the invention. Any person skilled in the art can modify or change the above-mentioned embodiments without departing from the spirit and scope of the present invention. Accordingly, it is intended that all equivalent modifications or changes which can be made by those skilled in the art without departing from the spirit and technical spirit of the present invention be covered by the claims of the present invention.