阅读说明：本技术 一种含有园艺黄荆根的杀菌组合物 (Bactericidal composition containing garden negundo chastetree roots ) 是由 周德超 于 2019-10-17 设计创作，主要内容包括：本发明公开一种含有园艺黄荆根的杀菌组合物,其主要由以下重量份比例的组分所制成：甲基异噻唑啉酮30-40份、园艺黄荆根40-55份、透骨草15-30份、菖蒲3-5份、马耳草1-2份、无患子果3-7份、紫苏叶油6-12份、磷酸二氢钾5-10份、壳寡糖3-5份、表面活性剂3-5份、防腐剂0.01-0.1份。本发明具有优异的杀菌效果,且对园艺黄荆根的新用途具有指导性意义。(The invention discloses a sterilizing composition containing garden negundo chastetree roots, which is mainly prepared from the following components in parts by weight: 30-40 parts of methylisothiazolinone, 40-55 parts of garden negundo chastetree root, 15-30 parts of garden balsam stem, 3-5 parts of calamus, 1-2 parts of herba hyperici japonici, 3-7 parts of soapberry, 6-12 parts of perilla leaf oil, 5-10 parts of monopotassium phosphate, 3-5 parts of chitosan oligosaccharide, 3-5 parts of surfactant and 0.01-0.1 part of preservative. The invention has excellent sterilization effect and instructive significance for the new application of the garden negundo chastetree roots.)

1. A sterilization composition containing garden vitex negundo roots is characterized by being mainly prepared from the following components in parts by weight: 30-40 parts of methylisothiazolinone, 40-55 parts of garden negundo chastetree root, 15-30 parts of garden balsam stem, 3-5 parts of calamus, 1-2 parts of herba hyperici japonici, 3-7 parts of soapberry, 6-12 parts of perilla leaf oil, 5-10 parts of monopotassium phosphate, 3-5 parts of chitosan oligosaccharide, 3-5 parts of surfactant and 0.01-0.1 part of preservative.

2. The bactericidal composition according to claim 1, which is prepared from the following components in parts by weight: 32-38 parts of methylisothiazolinone, 45-53 parts of garden negundo chastetree root, 17-26 parts of garden balsam stem, 3.2-4.8 parts of calamus, 1.2-1.8 parts of herba hyperici japonici, 3.5-6 parts of soapberry, 7-11 parts of perilla leaf oil, 6-9.5 parts of monopotassium phosphate, 3.4-4.6 parts of chitosan oligosaccharide, 3.2-4.3 parts of surfactant and 0.02-0.08 part of preservative.

3. The bactericidal composition according to claim 1, which is prepared from the following components in parts by weight: 33-36 parts of methylisothiazolinone, 47-52 parts of garden negundo chastetree root, 19-23 parts of garden balsam stem, 3.4-4.2 parts of calamus, 1.3-1.6 parts of herba hyperici japonici, 4-5 parts of soapberry, 8-10 parts of perilla leaf oil, 7-9 parts of monopotassium phosphate, 3.8-4.2 parts of chitosan oligosaccharide, 3.5-4.1 parts of surfactant and 0.03-0.06 part of preservative.

4. The bactericidal composition according to claim 1, which is prepared from the following components in parts by weight: 34 parts of methylisothiazolinone, 50 parts of garden negundo chastetree root, 20 parts of garden balsam stem, 4 parts of calamus, 1.5 parts of herba hyperici japonici, 4.5 parts of soapberry, 9 parts of perilla leaf oil, 8 parts of monopotassium phosphate, 4 parts of chitosan oligosaccharide, 4 parts of surfactant and 0.05 part of preservative.

5. The germicidal composition of any of claims 1-4, wherein the surfactant is stearic acid or sodium dodecylbenzenesulfonate.

6. The germicidal composition as claimed in any one of claims 1 to 5, wherein the preparation process comprises the steps of: mixing the garden golden larch root, the garden balsam stem, the calamus, the hypericum japonicum and the soapberry in parts by weight, adding 20-25 times of clear water, decocting for 5-6h, filtering to remove residues, adding the rest raw materials into the filtrate, and stirring for 30-45min at 20-30 ℃ to obtain the bactericidal composition.

7. The bactericidal composition of claim 6, wherein the boiling is performed with strong fire for 1 to 2 hours and then with slow fire for 3 to 5 hours.

Technical Field

The invention relates to the technical field of gardening negundo chastetree, in particular to a bactericidal composition containing gardening negundo chastetree roots.

Background

The horticultural vitex negundo is an excellent variety in vitex agnus-castus, is a small deciduous tree or shrub plant of vitex of Verbenaceae, and has fragrance throughout the plant. Square small branches, dense grey down. The leaves are opposite, palm-shaped to form compound leaves, the edges of the minor leaves are provided with a plurality of saw teeth, the upper part is green, the lower part is light green, and no hair or slight hair exists. The top of the cone-shaped inflorescence is large and bell-shaped, the top has a crown with split teeth which is purplish blue and bright, and the top has a lobe. The fruit is spherical, yellow brown to dark brown, is similar to black pepper seed in shape, has spicy fragrance, and is used as a seasoning in some areas. The flowering period is 6-10 months, and the flowering period in summer and autumn is positive, so that the aromatic plants are strong in ornamental value. Vitex agnus-castus is distributed in temperate or subtropical regions, including the middle part of Asia, the southern Europe, the Mediterranean region and the like, particularly the southern Turkish region has rich Vitex agnus-castus resources, and at present, some regions of China are introduced, such as Jiangsu, Zhejiang, Shanghai, Hubei, Chongqing, Sichuan, Anhui and the like.

Vitex agnus-castus is one of the commonly used herbs in Europe, and its therapeutic effect on diseases has been recognized in the United states, Germany, Japan, and other countries. Vitex agnus-castus fruits were documented as early as 2500 years ago to be used for the treatment of gynecological disorders such as dysmenorrhea, irregular menstruation, etc., and were said to be commonly used by herders and churches to reduce libido. In addition, since ancient Greece, the fruit has been used as a botanical drug for women's health. In turkey, residents use Vitex agnus-castus leaves to treat abdominal pain, fruits are used for diuresis, dispelling wind, and sedation, while flowers, leaves, and rhizomes are used to treat menstrual cycle disorders; in brazil, vitex agnus-castus is used for religious ceremony and park ornamental plants, and its twigs and fruits are also used for treating stomachache, headache, syphilis, etc.; in Iran folk, Vitex agnus-castus is used to treat milk disorders, convulsions, epilepsy, constipation, etc. Along with the continuous and intensive research on Vitex agnus-castus by foreign scholars, Vitex agnus-castus is gradually discovered to have estrogen-like effect and good curative effect on female diseases, Vitex agnus-castus fruit extract is approved to be used for treating irregular menstruation, premenstrual syndrome and mastalgia in Germany in 1992, and Vitex agnus-castus fruit is loaded into European pharmacopoeia to enable the Vitex agnus-castus fruit to have clear medicinal standards. Vitex agnus-castus contains numerous chemical components with biological activity. Casticin is the main chemical component and the characteristic component of casticin, and the content of casticin in casticin fruits is not less than 0.8 percent and can exert various biological activities such as anti-inflammation, anti-tumor, prolactin secretion inhibition and the like according to the regulation of European pharmacopoeia. The Vitex agnus-castus also contains abundant volatile oil components, mainly including cineole, myrtenol, pinene, sabinene, farnesene, geranene, caryophyllene and alpha-terpinyl acetate; flavones such as apigenin, luteolin, kaempferol-3-O-rutinoside, isoluteolin 6-c- (2-O-trans-caffeoyl) glucoside, vitexin and isoorientin; phenolic acids such as hydroxybenzoic acid, 3, 4-dihydroxybenzoic acid, and the like. In addition, carotenoid, chlorogenic acid, isochlorogenic acid, etc. are contained, and has antioxidant effect.

The research on the garden vitex negundo is mainly focused on the research on the medicinal value of the garden vitex negundo. In the prior art, the horticultural vitex negundo roots are used in bactericides, and researches show that the horticultural vitex negundo roots have potential bactericidal effects and can be used as raw material components of the bactericides or can obtain unexpected bactericidal effects.

Disclosure of Invention

The purpose of the invention is as follows: the invention aims to provide a sterilizing composition containing garden negundo chastetree roots, so that the sterilizing effect of the sterilizing composition is improved, and the sterilizing composition has instructive significance for new application of the garden negundo chastetree roots.

The technical scheme is as follows: the invention relates to a sterilizing composition containing garden negundo chastetree roots, which is mainly prepared from the following components in parts by weight: 30-40 parts of methylisothiazolinone, 40-55 parts of garden negundo chastetree root, 15-30 parts of garden balsam stem, 3-5 parts of calamus, 1-2 parts of herba hyperici japonici, 3-7 parts of soapberry, 6-12 parts of perilla leaf oil, 5-10 parts of monopotassium phosphate, 3-5 parts of chitosan oligosaccharide, 3-5 parts of surfactant and 0.01-0.1 part of preservative.

Preferably, the paint is mainly prepared from the following components in parts by weight: 32-38 parts of methylisothiazolinone, 45-53 parts of garden negundo chastetree root, 17-26 parts of garden balsam stem, 3.2-4.8 parts of calamus, 1.2-1.8 parts of herba hyperici japonici, 3.5-6 parts of soapberry, 7-11 parts of perilla leaf oil, 6-9.5 parts of monopotassium phosphate, 3.4-4.6 parts of chitosan oligosaccharide, 3.2-4.3 parts of surfactant and 0.02-0.08 part of preservative.

Preferably, the paint is mainly prepared from the following components in parts by weight: 33-36 parts of methylisothiazolinone, 47-52 parts of garden negundo chastetree root, 19-23 parts of garden balsam stem, 3.4-4.2 parts of calamus, 1.3-1.6 parts of herba hyperici japonici, 4-5 parts of soapberry, 8-10 parts of perilla leaf oil, 7-9 parts of monopotassium phosphate, 3.8-4.2 parts of chitosan oligosaccharide, 3.5-4.1 parts of surfactant and 0.03-0.06 part of preservative.

Preferably, the paint is mainly prepared from the following components in parts by weight: 34 parts of methylisothiazolinone, 50 parts of garden negundo chastetree root, 20 parts of garden balsam stem, 4 parts of calamus, 1.5 parts of herba hyperici japonici, 4.5 parts of soapberry, 9 parts of perilla leaf oil, 8 parts of monopotassium phosphate, 4 parts of chitosan oligosaccharide, 4 parts of surfactant and 0.05 part of preservative.

Preferably, the surfactant is stearic acid or sodium dodecylbenzenesulfonate.

Preferably, the preparation method comprises the following steps: mixing the garden golden larch root, the garden balsam stem, the calamus, the hypericum japonicum and the soapberry in parts by weight, adding 20-25 times of clear water, decocting for 5-6h, filtering to remove residues, adding the rest raw materials into the filtrate, and stirring for 30-45min at 20-30 ℃ to obtain the bactericidal composition.

Preferably, the boiling is carried out by firstly boiling for 1-2h with strong fire and then boiling for 3-5h with slow fire.

Compared with the prior art, the invention has the beneficial effects that: the sterilizing composition disclosed by the invention selects the horticultural negundo chastetree roots as one of the raw materials, and the horticultural negundo chastetree roots are matched with garden balsam stems, calamus, herba hyperici japonici, soapberry fruits, perilla leaf oil and the like, so that the raw materials are combined according to a reasonable proportion, and then the sterilizing composition has a better synergistic effect, so that the sterilizing composition has an excellent sterilizing effect, and the shelf life of the sterilizing composition can be prolonged by adding the preservative. In addition, the invention also has instructive significance for the new application of the garden vitex negundo root. In the preferred preparation method, the garden golden larch root, the garden balsam stem, the calamus, the hypericum japonicum and the soapberry are mixed, 20-25 times of clear water is added, and the mixture is boiled for 5-6 hours, so that the effective components in the garden golden larch root, the garden balsam stem, the calamus, the malus asiatica and the soapberry can be fully extracted, and the synergistic effect is enhanced. Through detection, the average bacteriostasis rate of the antibacterial agent is 93% for staphylococcus aureus, escherichia coli, candida albicans and the like.

Detailed Description

The technical solution of the present invention is described in detail by the following specific examples, but the scope of the present invention is not limited to the examples.

Example 1

A sterilization composition containing garden vitex negundo roots is mainly prepared from the following components in parts by weight: 30 parts of methylisothiazolinone, 55 parts of garden negundo chastetree root, 15 parts of garden balsam stem, 5 parts of calamus, 1 part of herba hyperici japonici, 7 parts of soapberry, 6 parts of perilla leaf oil, 10 parts of potassium dihydrogen phosphate, 3 parts of chitosan oligosaccharide, 5 parts of stearic acid and 0.01 part of preservative; the preparation method comprises the following steps: mixing the garden golden larch root, the garden balsam stem, the calamus, the hypericum japonicum and the soapberry according to the weight parts, adding 25 times of clear water, decocting for 1 hour by adopting strong fire, then decocting for 5 hours by adopting slow fire, filtering to remove residues, adding the rest raw materials into the filtrate, and stirring for 30min at the temperature of 30 ℃ to obtain the sterilizing composition.

The sterilizing composition of the embodiment selects the horticultural negundo chastetree roots as one of the raw materials, and the horticultural negundo chastetree roots are matched with garden balsam stems, calamus, herba hyperici japonici, soapberry fruits, perilla leaf oil and the like, so that the raw materials are combined according to a reasonable proportion, and have a better synergistic effect, so that the sterilizing composition has an excellent sterilizing effect, and the shelf life of the sterilizing composition can be prolonged by adding the preservative.

Example 2

A sterilization composition containing garden vitex negundo roots is mainly prepared from the following components in parts by weight: 40 parts of methylisothiazolinone, 40 parts of garden vitex negundo root, 30 parts of garden balsam stem, 3 parts of calamus, 2 parts of herba hyperici japonici, 3 parts of soapberry, 12 parts of perilla leaf oil, 5 parts of potassium dihydrogen phosphate, 5 parts of chitosan oligosaccharide, 3 parts of stearic acid and 0.1 part of preservative; the preparation method comprises the following steps: mixing the garden golden larch root, the garden balsam stem, the calamus, the hypericum japonicum and the soapberry according to the weight parts, adding 20 times of clear water, decocting for 2 hours by adopting strong fire, then decocting for 3 hours by adopting slow fire, filtering to remove residues, adding the rest raw materials into the filtrate, and stirring for 45min at the temperature of 20 ℃ to obtain the sterilizing composition.

The sterilizing composition of the embodiment selects the horticultural negundo chastetree roots as one of the raw materials, and the horticultural negundo chastetree roots are matched with garden balsam stems, calamus, herba hyperici japonici, soapberry fruits, perilla leaf oil and the like, so that the raw materials are combined according to a reasonable proportion, and have a better synergistic effect, so that the sterilizing composition has an excellent sterilizing effect, and the shelf life of the sterilizing composition can be prolonged by adding the preservative.

Example 3

A sterilization composition containing garden vitex negundo roots is mainly prepared from the following components in parts by weight: 34 parts of methylisothiazolinone, 50 parts of garden negundo chastetree root, 20 parts of garden balsam stem, 4 parts of calamus, 1.5 parts of herba hyperici japonici, 4.5 parts of soapberry, 9 parts of perilla leaf oil, 8 parts of monopotassium phosphate, 4 parts of chitosan oligosaccharide, 4 parts of sodium dodecyl benzene sulfonate and 0.05 part of preservative; the preparation method comprises the following steps: mixing the garden golden larch root, the garden balsam stem, the calamus, the hypericum japonicum and the soapberry according to the weight parts, adding 23 times of clear water, decocting for 1.5 hours by adopting strong fire, then decocting for 4 hours by adopting slow fire, filtering to remove residues, adding the rest raw materials into the filtrate, and stirring for 40min at 25 ℃ to obtain the sterilizing composition.

The sterilizing composition of the embodiment selects the horticultural negundo chastetree roots as one of the raw materials, and the horticultural negundo chastetree roots are matched with garden balsam stems, calamus, herba hyperici japonici, soapberry fruits, perilla leaf oil and the like, so that the raw materials are combined according to a reasonable proportion, and have a better synergistic effect, so that the sterilizing composition has an excellent sterilizing effect, and the shelf life of the sterilizing composition can be prolonged by adding the preservative.

Example 4

A sterilization composition containing garden vitex negundo roots is mainly prepared from the following components in parts by weight: 32 parts of methylisothiazolinone, 53 parts of garden vitex negundo root, 17 parts of garden balsam stem, 4.8 parts of calamus, 1.2 parts of herba hyperici japonici, 6 parts of soapberry fruit, 7 parts of perilla leaf oil, 9.5 parts of monopotassium phosphate, 3.4 parts of chitosan oligosaccharide, 4.3 parts of surfactant and 0.02 part of preservative; the preparation method comprises the following steps: mixing the garden golden larch root, the garden balsam stem, the calamus, the hypericum japonicum and the soapberry according to the weight parts, adding 22 times of clear water, decocting for 1.5 hours by adopting strong fire, then decocting for 4 hours by adopting slow fire, filtering to remove residues, adding the rest raw materials into the filtrate, and stirring for 35min at 23 ℃ to obtain the sterilizing composition.

The sterilizing composition of the embodiment selects the horticultural negundo chastetree roots as one of the raw materials, and the horticultural negundo chastetree roots are matched with garden balsam stems, calamus, herba hyperici japonici, soapberry fruits, perilla leaf oil and the like, so that the raw materials are combined according to a reasonable proportion, and have a better synergistic effect, so that the sterilizing composition has an excellent sterilizing effect, and the shelf life of the sterilizing composition can be prolonged by adding the preservative.

Example 5

A sterilization composition containing garden vitex negundo roots is mainly prepared from the following components in parts by weight: 38 parts of methylisothiazolinone, 45 parts of garden vitex negundo root, 26 parts of garden balsam stem, 3.2 parts of calamus, 1.8 parts of herba hyperici japonici, 3.5 parts of soapberry, 11 parts of perilla leaf oil, 6 parts of potassium dihydrogen phosphate, 4.6 parts of chitosan oligosaccharide, 3.2 parts of surfactant and 0.08 part of preservative; the preparation method comprises the following steps: mixing the garden golden larch root, the garden balsam stem, the calamus, the hypericum japonicum and the soapberry according to the weight parts, adding 24 times of clear water, decocting for 1.5 hours by adopting strong fire, then decocting for 4 hours by adopting slow fire, filtering to remove residues, adding the rest raw materials into the filtrate, and stirring for 42min at the temperature of 27 ℃ to obtain the sterilizing composition.

The sterilizing composition of the embodiment selects the horticultural negundo chastetree roots as one of the raw materials, and the horticultural negundo chastetree roots are matched with garden balsam stems, calamus, herba hyperici japonici, soapberry fruits, perilla leaf oil and the like, so that the raw materials are combined according to a reasonable proportion, and have a better synergistic effect, so that the sterilizing composition has an excellent sterilizing effect, and the shelf life of the sterilizing composition can be prolonged by adding the preservative.

As noted above, while the present invention has been shown and described with reference to certain preferred embodiments, it is not to be construed as limited thereto. Various changes in form and detail may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.