阅读说明：本技术 脑磁图扫描装置和脑磁图扫描方法 (Magnetoencephalogram scanning device and magnetoencephalogram scanning method ) 是由 盛经纬 邓春平 崔云扬 陈忠清 于 2020-12-31 设计创作，主要内容包括：本申请提供了一种脑磁图扫描装置和脑磁图扫描方法,涉及医学成像技术领域,解决了现有坐式头盔扫描效率低的问题。该装置包括具有多个探测器插槽的探测器插槽模块,探测器插槽模块用于同步控制多个探测器插槽承载的探测器的行程。本申请提供的脑磁图扫描装置通过模块化设计,大大提高了扫描效率。该装置使受试者以卧式体位接受扫描,不仅能避免坐式扫描头部负重、移动的缺陷,也能同时对头部主动限位,进一步降低头动导致的伪迹,提高了扫描过程的稳定性和扫描精度。此外,该装置还具有优秀的易用性,在不引入额外干扰的情况下,可以便捷地使每个探测器位于适合于不同受试者的最佳扫描位置,并在扫描完成后快速复位,方便受试者移出头部。(The application provides a magnetoencephalogram scanning device and a magnetoencephalogram scanning method, relates to the technical field of medical imaging, and solves the problem that an existing sitting helmet is low in scanning efficiency. The device comprises a detector slot module with a plurality of detector slots, wherein the detector slot module is used for synchronously controlling the stroke of the detectors carried by the plurality of detector slots. The magnetoencephalography scanning device provided by the application greatly improves scanning efficiency through modular design. The device makes the testee accept the scanning with horizontal position, not only can avoid sitting posture scanning head heavy burden, the defect of removal, also can initiatively spacing to the head simultaneously, further reduces the artifact that the head moved and leads to, has improved the stability and the scanning accuracy of scanning process. In addition, the device has excellent usability, can conveniently position each detector at the optimal scanning position suitable for different subjects under the condition of not introducing additional interference, and can be quickly reset after the scanning is finished, so that the subjects can conveniently move out of the head.)

1. An apparatus for magnetoencephalography scanning, comprising:

the detector slot module is provided with a plurality of detector slots and is used for synchronously controlling the strokes of the detectors carried by the plurality of detector slots.

2. The magnetoencephalography scanning device of claim 1, further comprising:

and the framework is detachably connected with the detector slot module and is used for bearing the detector slot module and the head of the testee.

3. The magnetoencephalography scanning device of claim 2, further comprising:

a module moving member detachably connected to the skeleton, the module moving member for controlling a distance of the probe from the head of the subject.

4. The apparatus according to claim 3, wherein the frame includes a frame through hole, the module moving part includes a module moving unit, the module moving unit includes an embedding end and an adjusting end opposite to the embedding end, the embedding end is detachably connected to the frame through hole, and the adjusting end is detachably connected to the detector slot module.

5. The magnetoencephalography scanning device of any of claims 2-4, further comprising:

and the resetting component is in linkage fit with the detector slot module and is used for resetting the detector.

6. The apparatus according to claim 5, wherein the frame comprises a protrusion, the reposition element comprises an elastic unit, the elastic unit comprises a fixed end and a reposition end opposite to the fixed end, the fixed end is fixedly connected to the protrusion, and the reposition end is fixedly connected to the probe slot module.

7. The magnetoencephalography scanning device of any of claims 2-4, further comprising:

and the head limiting part is detachably connected with the framework and is used for fixing the head of the testee.

8. The apparatus according to claim 7, wherein the head restraint member comprises a cushioning unit and a rigid unit detachably connected to the cushioning unit, the cushioning unit being located at an end of the head restraint member contacting the subject's head for cushioning a force when the rigid unit contacts the subject's head.

9. The apparatus according to any one of claims 1 to 4, wherein the probe slot comprises a receiving groove on a surface of the probe slot adjacent to the probe for receiving a fixing member capable of increasing a resistance between the probe and the probe slot.

10. The apparatus according to any one of claims 1 to 4, wherein the probe slot comprises anti-wear grooves at corners of the adjacent surface of the probe slot to the probe for reducing wear of the edge of the probe when in contact with the probe slot.

11. A magnetoencephalogram scanning method is applied to a magnetoencephalogram scanning device comprising a detector slot module, wherein the detector slot module is provided with a plurality of detector slots, and the magnetoencephalogram scanning method comprises the following steps:

and synchronously controlling the strokes of the detectors carried by the plurality of detector slots by using the detector slot modules.

12. The method of claim 11, wherein the apparatus further comprises a frame detachably connected to the probe slot module and a module moving member detachably connected to the frame, further comprising:

controlling a distance between the probe and the head of the subject by using the module moving component, wherein the skeleton is used for carrying the probe slot module and the head of the subject.

13. The method of claim 12, wherein the apparatus further comprises a head restraint removably coupled to the frame, further comprising:

fixing the head of the subject with the head restraint.

14. The magnetoencephalography scanning method of any one of claims 11-13, wherein the magnetoencephalography scanning device further comprises a reset component in linkage fit with the probe slot module, further comprising:

resetting the probe with the resetting component.

Technical Field

The application relates to the technical field of medical imaging, in particular to a magnetoencephalogram scanning device and a magnetoencephalogram scanning method.

Background

The magnetoencephalogram is a functional brain imaging technology for detecting a weak magnetic field generated by a nerve electrical signal, and has wide application in clinic and scientific research, including diagnosis and positioning of nervous system diseases such as epilepsy and the like, biomarker research of mental diseases, preoperative brain functional area positioning, brain cognitive neuroscience research and the like. However, most of the existing schemes for scanning the magnetoencephalogram based on the atomic Magnetometer (also called atomic Magnetometer, optical pump Magnetometer, optical Pumped Magnetometer, and OPM) are sitting, that is, a subject wears a wearable magnetoencephalogram helmet (magnetoencephalogram cap), and inserts a plurality of detectors into slots one by one, and after scanning is finished, the plurality of detectors need to be reset one by one, so that the scanning efficiency is greatly reduced, and the scanning process is relatively complex.

Disclosure of Invention

In view of this, the present application is directed to provide a magnetoencephalogram scanning apparatus and a magnetoencephalogram scanning method, which solve the problems of low scanning efficiency and complex scanning process of the sitting type scanning helmet in the prior art.

In a first aspect, there is provided a magnetoencephalography scanning device comprising: the detector slot module is provided with a plurality of detector slots and is used for synchronously controlling the strokes of the detectors carried by the plurality of detector slots.

With reference to the first aspect, in certain implementations of the first aspect, the magnetoencephalography device further includes: and the framework is detachably connected with the detector slot module and is used for bearing the detector slot module and the head of the testee.

With reference to the first aspect, in certain implementations of the first aspect, the magnetoencephalography device further includes: and the module moving component is detachably connected with the framework and is used for controlling the distance between the detector slot module and the head of the subject.

With reference to the first aspect, in certain implementations of the first aspect, the framework includes a framework through hole, the module moving part includes a module moving unit, the module moving unit includes an embedding end and an adjusting end opposite to the embedding end, the embedding end is detachably connected to the framework through hole, and the adjusting end is detachably connected to the detector slot module.

With reference to the first aspect, in certain implementations of the first aspect, the magnetoencephalography device further includes: and the resetting component is in linkage fit with the detector slot module and is used for quickly resetting the detector.

With reference to the first aspect, in certain implementation manners of the first aspect, the framework includes a protruding portion, the reset component includes an elastic unit, the elastic unit includes a fixed end and a reset end opposite to the fixed end, the fixed end is fixedly connected to the protruding portion, and the reset end is fixedly connected to the probe slot module.

With reference to the first aspect, in certain implementations of the first aspect, the magnetoencephalography device further includes: and the head limiting part is detachably connected with the framework and is used for fixing the head of the testee.

With reference to the first aspect, in certain implementations of the first aspect, the head restraint includes a buffering unit located at an end of the head restraint in contact with the head of the subject, for buffering an acting force of the head restraint when in contact with the head of the subject.

With reference to the first aspect, in certain implementations of the first aspect, the probe slot includes a receiving groove, located on a surface of the probe slot adjacent to the probe, for bearing a fixing component capable of increasing a resistance between the probe and the probe slot.

With reference to the first aspect, in certain implementations of the first aspect, the detector slot includes an anti-abrasion groove located at a corner position of an adjacent surface of the detector slot and the detector, and configured to reduce abrasion when the edge of the detector contacts the detector slot.

In a second aspect, there is provided a magnetoencephalogram scanning method applied to a magnetoencephalogram scanning apparatus including a detector slot module, where the detector slot module has a plurality of detector slots, and the method includes: and synchronously controlling the strokes of the detectors carried by the plurality of detector slots by using the detector slot modules.

With reference to the second aspect, in certain implementations of the second aspect, the apparatus further includes a framework detachably connected to the probe slot module and a module moving component detachably connected to the framework, and further includes: controlling a distance between the probe and the head of the subject by using the module moving component, wherein the skeleton is used for carrying the probe slot module and the head of the subject.

With reference to the second aspect, in certain implementations of the second aspect, the magnetoencephalography scanning device further includes a head restraint component detachably connected to the frame, and further includes: fixing the head of the subject with the head restraint.

With reference to the second aspect, in certain implementations of the second aspect, the magnetoencephalography scanning device further includes a reset component in linkage fit with the probe slot module, and further includes: resetting the probe with the resetting component.

The application provides a specific detector and a head bearing device aiming at horizontal magnetoencephalography, namely a magnetoencephalography scanning device. The magnetoencephalography scanning device is provided with the detector slot modules with the plurality of detector slots through modular design, so that the strokes of the plurality of detectors can be synchronously controlled, the scanning efficiency is greatly improved, and meanwhile, each detector can be conveniently and fast positioned at the optimal scanning position suitable for different testees. The magnetoencephalography scanning device further comprises a framework detachably connected with the detector slot module and used for bearing the detector slot module and the head of a subject, the framework is provided with a connecting part, the head of the subject can be scanned in a horizontal body position through the connecting part and the scanning bed, and the defects of head loading and moving of the subject in the sitting type scanning helmet in the prior art are overcome.

The magnetoencephalography scanning device also comprises a module moving component which is detachably connected with the framework and is used for controlling the distance between the detector slot module and the head of the testee. The magnetoencephalography scanning device further comprises a resetting component in linkage fit with the detector slot module, and the resetting component is used for resetting the detector quickly, so that a subject can move out of the head conveniently, and the scanning efficiency and the application convenience are improved. The brain magnetic image scanning device also comprises a head limiting component detachably connected with the framework and used for fixing the head of the subject and actively limiting the head of the subject, thereby further reducing the artifacts caused by head movement and improving the stability and the scanning precision in the scanning process.

The detector slot comprises a containing groove, the containing groove is positioned on the surface of the detector slot adjacent to the detector and is used for bearing a fixing part capable of increasing the resistance between the detector and the detector slot, and the defects that in the prior art, the scanning precision of the sitting type scanning helmet is low due to the fact that the head of a subject shakes, and the position between the detector and the head of the subject changes are effectively overcome. The detector slot comprises an anti-abrasion groove, is positioned at the corner position of the adjacent surface of the detector slot and the detector, and is used for reducing abrasion of the edge of the detector when the edge of the detector is contacted with the detector slot, prolonging the service life of the detector and the detector slot and reducing the cost of clinical application.

Drawings

Fig. 1 is a schematic structural diagram of a magnetoencephalography scanning device according to an embodiment of the present disclosure.

Fig. 2 is a schematic structural diagram of a probe slot module of a magnetoencephalography scanning device according to an embodiment of the present disclosure.

Fig. 3 is a schematic structural diagram of a framework of a magnetoencephalography scanning device according to an embodiment of the present disclosure.

Fig. 4 is a schematic structural diagram illustrating a module moving part of a magnetoencephalography scanning device according to an embodiment of the present application.

Fig. 5 is a partially enlarged schematic structural diagram of a module moving part of the magnetoencephalography scanning device according to an embodiment of the present application, the module moving part being not inserted into a through hole of a framework.

Fig. 6 is a schematic structural diagram of a magnetoencephalography scanning device provided in an embodiment of the present application in a state of being inserted into a detector.

Fig. 7 is a schematic structural diagram of a head restraint part of a magnetoencephalography scanning device according to an embodiment of the present application.

Fig. 8 is a partially enlarged schematic structural diagram of a head restraint part of the magnetoencephalography scanning device according to an embodiment of the present application, the head restraint part being inserted into a through hole of a frame.

Fig. 9 is a schematic partial enlarged structural view of a reduction component of a magnetoencephalography device according to an embodiment of the present application.

Fig. 10 is a schematic flow chart of a magnetoencephalogram scanning method according to an embodiment of the present disclosure.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

The traditional magnetoencephalogram adopts a superconducting Quantum interferometer (SQUID) as a magnetic field detector, the detector can normally work only when the detector is kept at an extremely low temperature of liquid helium, therefore, the detector needs to be packaged and fixed in a Dewar tank, and a vacuum heat insulation layer with the thickness of several centimeters is arranged between the detector and the outside, so that the detector is limited to be attached to the scalp to obtain stronger signal intensity, and a helmet made of a rigid Dewar has no portability, cannot be matched with different human head profiles, and has poor universality in the actual application process. In addition, the scheme to atomic magnetometer magnetocardiogram scanning at present is mostly sitting type, and the person who promptly receives the examination wears wearable magnetocaloric helmet (magnetocaloric cap), before the scanning, need insert a plurality of detectors one by one in the detector slot, after the scanning, need reset a plurality of detectors one by one again, and such operating mode obviously makes scanning efficiency greatly reduced and operation process complicated relatively. The magnetoencephalography scanning device provided by the application can synchronously control the plurality of detectors to be inserted into the detector slots and synchronously reset the plurality of detectors, so that the scanning efficiency is greatly improved, and the operation process is simplified.

In addition, it should be noted that spatial registration is usually required before the magnetic brain scan to determine the relative position of each detector and the head of the subject, so as to perform fusion with the structural images such as magnetic resonance, CT, etc. to perform source localization on the cerebral cortex neural activity. Accurate source positioning is required to ensure that the head of the subject and the detector and detector remain fixed relative to each other during the scan.

In existing atomic magnetometer-based magnetoencephalography techniques, a subject typically wears a wearable magnetoencephalography device in a seated position. The device may be a rigid helmet or a flexible cap with rigid probe slots mounted on a flexible substrate. Although the rigid helmet can better fix the relative position between the detectors, the applicable head shape range is limited, the load applied to the head of a subject is large, and discomfort is easily caused so as to intervene in brain activity and further influence the scanning result. Although the flexible cap can adapt to the head shape in a wider range, the relative position between the detectors in the scanning process cannot be fixed, and the relative position can be gradually changed due to the elasticity of the flexible substrate or the slight shaking of the head, so that the accuracy of source positioning can be reduced, and the influence of the mutual crosstalk of the adjacent detectors can also be increased. In addition, no matter a rigid helmet or a flexible cap, the shaking of the head of the subject in the scanning process is difficult to limit, so that obvious motion artifacts appear in the measured signals, the situation is particularly obvious when the subject adopts a sitting posture, and the quality of the acquired brain magnetic signals is greatly reduced. In addition, movement of both the subject's head and the detector during scanning can cause the relative position of the detector and the subject's head to change, such that the relative position measured by the pre-scan spatial registration is no longer accurate, thereby reducing the accuracy of the source location.

The utility model provides a magnetoencephalogram scanning device realizes that a plurality of detectors of synchro control insert the detector slot and a plurality of detectors of synchronous reset through modes such as modular design, and every detector also can independently move, changes the depth of insertion to the head profile (covering adult, children) that the adaptation matches different testers has showing the scanning efficiency and the convenient degree of application that have improved the magnetoencephalogram. In addition, the magnetoencephalography scanning device provided by the application actively limits the head shaking of the testee and the change of the position of the detector in the scanning process by using horizontal scanning body positions, the active head limiting device, the accommodating groove capable of limiting the degree of freedom of the detector and providing resistance for the detector, the non-direct contact between the detector and the head surface of the testee and other designs and methods, and obviously improves the quality of measured magnetoencephalography signals and the accuracy of source positioning.

In an embodiment of the present application, the magnetoencephalogram scanning apparatus includes a detector slot module having a plurality of detector slots, where the detector slot module can synchronously control the strokes of detectors carried by the plurality of detector slots, such as positioning and resetting of the detectors, and synchronously control the plurality of detectors to be inserted into the detector slots and synchronously reset the plurality of detectors, thereby greatly improving scanning efficiency and application convenience.

The embodiments of the present application will be described in detail below with reference to the accompanying drawings.

Fig. 1 is a schematic structural diagram of a magnetoencephalography scanning device according to an embodiment of the present disclosure. As shown in fig. 1, the magnetic brain image scanning apparatus 10 includes a plurality of detector slot modules 20, a frame 30 detachably connected to the plurality of detector slot modules 20, a module moving member 40 and a head limiting member 50 detachably connected to the frame 30, and a plurality of restoring members 60 cooperatively engaged with the plurality of detector slot modules 20. The plurality of probe slot modules 20 and the plurality of reset components 60 are in a one-to-one correspondence relationship, that is, each probe slot module 20 corresponds to one reset component 60.

The magnetoencephalography device 10 has a shape that conforms to the contour of a human head such that a subject's head may enter the magnetoencephalography device 10. The skeleton 30 has a shell that conforms to the contour of the head of a subject (e.g., a human body), and a plurality of hollowed-out regions extending through the shell. The plurality of detector slot modules 20 and the plurality of hollow areas are in one-to-one correspondence, so that each detector slot module 20 is detachably mounted in the corresponding hollow area.

The module moving part 40 is detachably connected to the frame 30 for adjusting the distance between the probe slot module 20 and the head of the subject. The head restraint 50 is removably attached to the frame 30 for securing the head of the subject. The reset device 60 is cooperatively engaged with the prober slot module 20 for resetting the plurality of probers.

It should be noted that the detector slot module 20 includes a plurality of detector slots, the plurality of detector slots can carry a plurality of detectors, and each detector slot corresponds to each detector one-to-one, so that one detector slot module 20 can synchronously control the strokes of the plurality of detectors, such as positioning and resetting of the detectors, and the convenience and the practicability of clinical application are greatly improved.

Fig. 2 is a schematic structural diagram of a probe slot module of a magnetoencephalography scanning device according to an embodiment of the present disclosure. As shown in fig. 2, the probe slot module 20 has a circular arc shape adapted to the head contour, the probe slot module 20 includes a plurality of probe slots 21 and a module through hole 22, and the probe slot module 20 can synchronously control the stroke of the probes carried by the plurality of probe slots 21, for example, synchronously control the positioning and resetting of the plurality of probes, and the like.

It should be noted that, in an embodiment of the present application, the probe slot 21 has a rectangular cross section and protrudes from the outer surface of the probe slot module 20. Each probe slot module 20 includes three module through holes 22 for removably connecting to the frame 30. The module through holes 22 are cylindrical through holes, and protrude from the outer surface of the probe slot module 20, wherein two module through holes 22 have the same structure and are located at the positions corresponding to the edges of the probe slot module 20, and the other module through hole 22 is located at the position close to the center of the probe slot module 20. On the outer surface of the detector slot module 20, except for three module through holes 22, a plurality of detector slots 21 are orderly arranged at other positions, and adjacent detector slots 21 are slightly spaced or closely connected. The plurality of detector slots 21 are configured on the outer surface of the detector slot module 20, so that the plurality of detectors carried by the plurality of detector slots 21 can adapt to the head contour of different subjects (such as adults and children), and each detector can be conveniently located at the optimal scanning position suitable for different subjects.

In an embodiment of the present application, the cross section of the probe slot 21 is rectangular, and may also be a structure with other shapes (for example, a square shape, which may be configured according to the shape of the probe), and the positions of the three module through holes 22 may also be at other positions on the outer surface of the probe slot module 20, which is not limited in this application.

It should be noted that the end faces of the probes are all located below the inner curved surface of the probe slot module 20.

In an embodiment of the present application, the probe slot 21 includes a receiving groove 211, and the receiving groove 211 is located on a surface of the probe slot 21 adjacent to the probe and is used for bearing a fixing component capable of increasing resistance between the probe and the probe slot 21. The receiving groove 211 is located at the center of the four surfaces of the probe slot 21, has a direction parallel to the probe slot 21, is two-sectioned, is respectively close to the inner and outer surfaces of the probe slot module 20, and has a cross section ranging from a semicircle to a circle. The holding tank 211 does not link up detector slot 21, does not do the restriction to the degree of depth of holding tank 211 in this application for insert the fixed part who increases the resistance, increase the resistance between detector and the detector slot 21 and restrict the degree of freedom, guarantee under the condition that does not have external force, the detector can be fixed and can not slide or rock at the inserted degree of depth in the detector slot 21.

It should be noted that, most of the scanning schemes for the magnetoencephalogram in the prior art are sitting, and the subject wears the wearable magnetoencephalogram helmet and inserts the detector into the slot. Although the scheme can enable the testee to have more freedom of movement and perform more diversified tasks, the head of the testee is easy to shake when the testee is in a sitting posture, so that the magnetic helmet can shake along with the head of the testee, and the position between the detector in the detector slot and the head of the testee is expected to change in the scanning process, so that the precision of spatial registration is greatly reduced, and a great error exists in the neural activity tracing and positioning. The holding tank 211 structure in this application embodiment for insert the fixed part who increases the resistance, increase the resistance between detector and the detector slot 21 and restrict the degree of freedom, guarantee under the state that the head slightly rocked, keep the position between the head of detector and the examinee in the slot can not change at the scanning in-process, the detector can be fixed and can not slide or rock at the depth of inserting, improved scanning process's stability and scanning accuracy.

In an embodiment of the present application, the cross-sectional shape of the accommodating groove 211 is not necessarily limited to a semicircle to a circle (i.e. the central angle of the cross-sectional circle is 180 degrees to 360 degrees), and may be other shapes, the position and the direction in the probe slot 21 are not uniformly limited, the fixing component may be a silica gel column or other components capable of providing resistance, and the cross-sectional shape and the fixing component of the accommodating groove 211 are not uniformly limited in this application.

In an embodiment of the present application, the detector slot 21 includes anti-wear grooves 212, and the anti-wear grooves 212 are located at corners of adjacent surfaces of the detector slot 21 and the detector, are parallel to and extend through the detector slot 21, and have the same size. The location and size of the wear-resistant groove 212 in the prober slot 21 is not uniformly defined in this application.

It should be noted that the wear-proof slot 212 of the probe slot 21 is used to prevent the edge of the probe from wearing when contacting the probe slot 21. The detector among the prior art is the cube structure that the corner is the right angle mostly, and detector slot 21 in this application also is the right angle shape structure, is inserting the detector in the in-process of detector slot 21, and the condition that the corner of detector touched detector slot 21's corner position appears very easily, leads to detector and detector slot 21 very easily to be worn and torn, has greatly shortened detector and detector slot 21's life, has increased the applied cost of brain magnetism scanning.

The wear-resistant groove 212 provided by the embodiment of the application reserves the space of the detector in the detector slot 21, effectively reduces the condition that the corners of the detector touch the corner positions of the detector slot 21 in the process of inserting the detector into the detector slot 21, and prevents the detector and the detector slot 21 from being worn to a great extent, thereby prolonging the service life of the detector and the detector slot 21 and reducing the application cost of brain magnetic scanning.

Fig. 3 is a schematic structural diagram of a framework of a magnetoencephalography scanning device according to an embodiment of the present disclosure. As shown in fig. 3, the framework 30 provided in the embodiment of the present application includes a framework through hole 31, a protrusion 32, and a connection portion 33, which are made of a rigid material and are used for bearing the probe slot module 20 and the head of the subject. The skeleton 30 has a shape similar to the contour of the head of a human body, and has a five-large hollowed-out structure as a whole, and is used for corresponding to the corresponding detector slot module 20. The positions of the five hollow structures are respectively the left part, the right part, the front part, the top part and the rear part of the head of the testee. Correspondingly, each hollow structure is provided with a framework through hole 31 and two protrusions 32, the protrusions 32 vertically extend outwards from the outer surface of the hollow structure where the protrusions are located, and the number and the direction of the framework through holes 31 and the number and the direction of the protrusions 32 are not uniformly limited in the application.

It should be noted that the frame through hole 31 has an internal thread structure for mounting the module moving member 40 and the head restraint member 50. The bosses 32 serve to nest the probe slot modules 20. The frame 30 is fixedly connected with the scanning bed through a connecting part 33, so that the subject can receive scanning in a horizontal posture.

It should be noted that, in the existing schemes for scanning the magnetoencephalogram of the atomic magnetometer, wearable magnetoencephalography devices are mostly worn in a sitting posture, and the schemes are difficult to limit the shaking of the head of a subject during scanning, so that the measured signals have obvious motion artifacts, and the quality of the acquired magnetoencephalography signals is greatly reduced.

The framework 30 provided by the embodiment of the application can be fixedly connected with the scanning bed through the connecting part 33, so that a subject can receive scanning in a horizontal posture. When the testee is in a horizontal body position, the head basically cannot shake and is in a stable state, obvious motion artifacts caused by the change of the position of the head in the scanning process cannot occur, and the stability and the scanning precision in the scanning process are improved to a certain extent. Meanwhile, because the positions of the detectors and the head are relatively fixed in the scanning process, the positioning result of the nerve activity source is more accurate. In addition, in the prior art, the subject wears the wearable magnetoencephalography helmet in a sitting posture, and the defect of head weight is overcome.

In an embodiment of the present application, the frame through hole 31 does not need to be an internal thread structure, and the height of the protruding portion 32 and the connection manner of the connection portion 33 and the scanning bed are not limited in the present application.

Fig. 4 is a schematic structural diagram illustrating a module moving part of a magnetoencephalography scanning device according to an embodiment of the present application. As shown in fig. 4, the module moving part 40 provided in the embodiment of the present application includes an embedded end 41 and an adjusting end 42, and the module moving part 40 is used for controlling the distance between the probe slot module 20 and the head of the subject.

It should be noted that the embedded end 41 and the adjusting end 42 are a split structure, and the embedded end 41 includes a threaded end 411 and a fixed end 412. The threaded end 411 is an external thread structure, and is inserted into the frame through hole 31 and engaged with the frame through hole 31 to be screwed in or out, so as to control the connection between the module moving member 40 and the frame 30. The fixing end 412 has a through hole perpendicular to the insertion end 41, and correspondingly, the adjustment end 42 has a through hole perpendicular to the adjustment end 42, which is the same size as the through hole of the fixing end 412. By arranging the circular hole of the fixing end 412 and the circular hole of the adjusting end 42 in an overlapping manner, a cylinder having a size corresponding to the diameter of the circular holes is inserted into the overlapping circular holes to connect the embedded end 41 and the adjusting end 42 together. The recessed portion between the embedded end 41 and the adjustment end 42 clamps the probe slot module 20.

It should be noted that, in the present application, the structures and the connection manners of the embedded end 41 and the adjusting end 42 are not limited in a unified manner, as long as the function of controlling the distance between the probe slot module 20 and the head of the subject can be realized.

Fig. 5 is a partially enlarged schematic structural diagram of a module moving part of the magnetoencephalography scanning device according to an embodiment of the present application, the module moving part being not inserted into a through hole of a framework. As shown in fig. 5, in an embodiment of the present invention, after the circular hole of the fixing end 412 of the embedding end 41 inserted from the inside of the probe slot module 20 and the circular hole of the adjusting end 42 inserted from the outside of the probe slot module 20 are aligned in a superposition manner, a small cylinder with a diameter consistent with the diameter of the superposed circular holes is inserted to realize the connection between the module moving part 40 and the probe slot module 20.

In the present application, the connection manner of the module moving part 40 and the prober socket module 20 is not limited in a unified manner.

In one embodiment of the present application, the probe slot module 20 is pushed inward until the end surface of the threaded end 411 contacts the frame 30, and then the adjusting end 42 is rotated to engage the insertion end 41 with the frame through hole 31, and further screwed, so as to insert the module moving member 40 into the frame through hole 31.

In the present application, the manner in which the module moving member 40 is fitted into the skeleton through-hole 31 is not limited in any way.

Fig. 6 is a schematic structural diagram of a magnetoencephalography scanning device provided in an embodiment of the present application in a state of being inserted into a detector. At this point, all of the prober socket modules 20 are in the outermost position, as shown in FIG. 6. After the head of the subject enters the magnetoencephalography scanning device 10, the probe slot modules 20 are pushed inwards one by one until the front end of the embedded end 41 contacts the framework 30, at the moment, the adjusting end 42 starts to rotate to enable the embedded end 41 to be meshed with the framework through hole 31, and the detector is further screwed until all the probes contact the head of the subject.

It should be noted that the probe that first contacts the head of the subject is gradually pushed outward as the probe slot module 20 continues to approach the skeleton 30, so that the depth of insertion of each probe is different in the final state.

In an embodiment of the present application, after all the detectors contact the head of the subject, the module moving component 40 is rotated outward by one turn, so that all the detectors are retracted by 1mm, which not only avoids discomfort caused by direct contact between the detectors and the head of the subject, but also avoids the change of the detector position caused by slight shaking of the head of the subject during the scanning process, thereby affecting the result of the magnetoencephalography.

It should be noted that, in the present application, the distance and the manner of withdrawing the probe are not limited in a unified manner, as long as the discomfort of the subject caused by the interaction force generated between the probe and the head of the subject can be avoided.

Fig. 7 is a schematic structural diagram of a head restraint part of a magnetoencephalography scanning device according to an embodiment of the present application. As shown in fig. 7, the corner of the probe slot module 20 is provided with an arc-shaped groove for accommodating the head limiting member 50 to connect with the frame through hole 31. The head restraint 50 includes a cushion unit 51, a spacer 52, and a bolt 53, wherein the spacer 52 and the bolt 53 serve as a rigid unit. The buffer unit 51 is of a silica gel pad structure, the outermost side of the gasket 52 is of a ring structure for bearing the buffer unit 51, and the middle of the gasket 52 is of a funnel type structure capable of bearing a structure similar to a screw. The diameter of the buffer unit 51 can be slightly smaller than the outermost diameter of the spacer 52, and after the spacer 52 and the bolt 53 are screwed together by screws, the buffer unit 51 can be adhered to the surface of the spacer 52, or the diameter of the buffer unit 51 can be configured to be consistent with the inner diameter of the circular ring structure of the spacer 52, so that the buffer unit 51 is just clamped inside the circular ring structure of the spacer 52. It should be noted that the thickness of the buffer unit 51 needs to be slightly greater than the thickness of the circular ring structure of the pad 52, so that after the buffer unit 51 and the circular ring structure of the pad 52 are fixed, the outer surface of the buffer unit 51 needs to be in contact with the head of the subject, rather than the pad 52 and other structures directly contacting the head of the subject.

Bolt 53 is a hollow internal thread structure for carrying a structure similar to a screw, and washer 52 and bolt 53 can be connected together by using the screw, and the external surface of bolt 53 is an external thread structure. The buffer unit 51 can reduce the acting force when the head limiting part 50 contacts with the head of the subject, and avoid the head discomfort of the subject caused by the direct contact of the rigid structure and the head of the subject.

In the present application, the structure of the head restraint member 50 is not limited to a uniform structure as long as the head position of the subject can be fixed.

Fig. 8 is a partially enlarged schematic structural diagram of a head restraint part of the magnetoencephalography scanning device according to an embodiment of the present application, the head restraint part being inserted into a through hole of a frame. As shown in fig. 8, a screw and a washer 52 detachably connected to the washer 52 are inserted from the inside of the frame through hole 31, and a bolt 53 is inserted from the outside of the frame through hole 31, so that the screw engages with the hollow internal thread of the bolt 53 and is further screwed until the screw is completely screwed into the hollow internal thread structure of the bolt 53. Then, the cushion unit 51 is inserted inside the circular ring structure of the spacer 52. By turning the bolt 53, the bolt 53 is adjusted to screw into the length of the skeleton through-hole 31. The length of the bolt 53 screwed into the skeleton through hole 31 can be adjusted according to different head profiles of the testee, so that the head position of the testee can be fixed aiming at the heads of different testees.

In one embodiment of the present application, after the head of the subject enters the magnetoencephalography device, the head restraint member 50 is screwed inward until the buffer unit 51 contacts the head of the subject. After the scanning is finished, the head restraint 50 is screwed out. In the embodiment, four limiting positions, namely front, top, left and right, are adopted, so that the limiting positions can be increased or decreased according to actual requirements, and the limiting positions are not uniformly limited.

The sitting helmet in the prior art does not limit the head of the subject, the head of the subject is easy to shake in the scanning process, and the position of the head of the subject is changed, so that the position between the detector and the head of the subject is changed in the scanning process, and the stability and the scanning accuracy of the scanning process are reduced.

In the embodiment, the head limiting component 50 is designed to actively fix the head of the subject, so that the change of the head position of the subject in the scanning process is reduced, even the head position of the subject is always in a fixed position state in the scanning process, and the stability and the scanning accuracy in the scanning process are improved.

Fig. 9 is a schematic partial enlarged structural view of a reduction component of a magnetoencephalography device according to an embodiment of the present application. As shown in fig. 9, a resetting component 60 provided in an embodiment of the present application is used for resetting the probe, and the resetting component 60 includes an elastic unit, and the elastic unit includes a fixed end 61 and a resetting end 62. The outermost end of the lug boss 32 of the frame 30 is provided with a through hole 321 perpendicular to the direction of the lug boss 32, and the edge of the module through hole 22 is provided with a hook locking structure 221. The elastic unit may be a spring structure, the fixed end 61 is fixedly connected with the through hole 321, and the reset end 62 is fixedly connected with the hook locking structure 221.

It should be noted that, when all the probe slot modules 20 are at the outermost position before the brain magnetic scan, the spring structure of the restoring member 60 is in the initial equilibrium state or the contracted state. When the head of the examinee enters the magnetoencephalography scanning device 10, the detector slot modules 20 are pushed inwards one by one until the front end face of the module moving part 40 touches the framework 30, at the moment, the spring structure is in a stretching state, and if the pushing force is removed in the process of pushing the detector slot modules 20 inwards, the detector slot modules 20 can rebound outwards. In the present application, the structure of the reset device 60 is not limited to unity as long as the function of quick reset can be realized.

After the head of the subject is scanned, the module moving member 40 is outwardly screwed, and when the external teeth of the insertion end 41 are separated from the internal teeth of the frame through hole 31, the remaining stroke can be directly returned to the initial position by the elastic unit.

In this embodiment, to reduce the workload, the probe slot module 20 at the back of the head of the subject may be fixed to the frame 30 and not movable. The rear portion of the probe slot module 20 may also be configured to be removable, similar to other probe slot modules 20, and is not limited herein.

Fig. 10 is a schematic flow chart of a magnetoencephalogram scanning method according to an embodiment of the present disclosure. As shown in fig. 10, the magnetoencephalogram scanning method provided in the embodiment of the present application includes steps S10 to S40.

In step S10, the probe slot module 20 is used to synchronously control the strokes of the probes carried by the plurality of probe slots 21.

And step S20, controlling the distance between the probe and the head of the subject by using the module moving component 40, wherein the framework 30 is used for carrying the probe slot module 20 and the head of the subject.

In step S30, the head of the subject is fixed by the head restraint 50.

In step S40, the probe is reset by the resetting unit 60.

It should be noted that the magnetoencephalography scanning method provided by the embodiment shown in fig. 10 can be applied to the magnetoencephalography scanning device mentioned in the above embodiment. Specifically, step S10, the magnetoencephalography scanning device includes a probe slot module 20 having a plurality of probe slots 21. In step S20, the apparatus further includes a frame 30 detachably connected to the probe slot module 20 and a module moving member 40 detachably connected to the frame 30. Step S30, the apparatus further comprises a head restraint 50 removably attachable to the frame 30. In step S40, the apparatus further includes a reset component 60 cooperating with the probe slot module 20.

It should be noted that the execution sequence of the above steps is not fixed, for example, the head of the subject may be fixed by the head-limiting component 50, and then the distance between the detector and the head of the subject may be controlled by the module moving component 40.

The magnetoencephalography scanning method utilizes the detector slot module 20 to synchronously control the strokes of a plurality of detectors, and improves the scanning efficiency. The distance between the detector and the head of the subject is controlled by the module moving part 40 so that each detector is located at an optimal scanning position suitable for different subjects. The head of the subject is fixed by the head limiting part 50, so that the head of the subject cannot slide or shake in the scanning process, and the stability and the scanning precision of the scanning process are improved. The detector is quickly reset by the resetting component 60, so that the scanning efficiency and the application convenience are improved.

The above description is only exemplary of the present application and should not be taken as limiting the present application, as any modifications, equivalents and the like that are within the spirit and principle of the present application should be included in the scope of the present application.