阅读说明：本技术 一种用于无损检测皮下组织液中葡萄糖的装置 (Device for nondestructive testing of glucose in subcutaneous tissue fluid ) 是由 逯纪涛 徐萍 朱润龙 于 2019-10-12 设计创作，主要内容包括：本发明公开了一种用于无损检测皮下组织液中葡萄糖的装置,属于生物医疗检测技术领域。主要包括检测主体、用于检测患者皮下组织液中葡萄糖含量的血糖检测头、控制元件、电源,血糖检测头包括壳体、倾斜设于壳体内一角处且侧壁设有多个用于产生激光的光源的光源板、准直透镜、反光板、超声传感器、粘贴片；通过可调谐的脉冲激光器作为光源,进行检测时,可调节多个光源同时发射不同波长激光,多个由上至下依次部分光源发射的激光在反光板上会产生不同的反射角,因此在检测者检测部位形成一个检测区域进行多点位检测,提高检测效率,增加检测结果的精确度；本发明具有检测精确、使用寿命长、智能一体化的优点,适合大量推广。(The invention discloses a device for nondestructive testing of glucose in subcutaneous tissue fluid, and belongs to the technical field of biomedical testing. The blood glucose detector mainly comprises a detection main body, a blood glucose detection head for detecting the content of glucose in subcutaneous tissue fluid of a patient, a control element and a power supply, wherein the blood glucose detection head comprises a shell, a light source plate, a collimating lens, a reflecting plate, an ultrasonic sensor and an adhesive sheet, the light source plate is obliquely arranged at one corner in the shell, and the side wall of the light source plate is provided with a plurality of light sources for generating laser; when the tunable pulse laser is used as a light source for detection, the tunable pulse laser can adjust a plurality of light sources to simultaneously emit laser with different wavelengths, and the laser emitted by a plurality of partial light sources in sequence from top to bottom can generate different reflection angles on the reflector, so that a detection area is formed at the detection part of a detector for multi-point detection, the detection efficiency is improved, and the accuracy of a detection result is increased; the invention has the advantages of accurate detection, long service life and intelligent integration, and is suitable for mass popularization.)

1. A device for nondestructive testing of glucose in subcutaneous tissue fluid is characterized by mainly comprising a testing main body (1), a blood glucose testing head (2) which is arranged at one end of the testing main body (1) and is used for testing the glucose content in subcutaneous tissue fluid of a patient, a control element (3) which is arranged in the testing main body (1) and is connected with the blood glucose testing head (2) through a power line, and a power supply;

the blood sugar detection head (2) comprises a shell (20), a light source plate (21) which is obliquely arranged at one corner in the shell (20) and the side wall of which is provided with a plurality of laser sources (200), collimating lenses (22) which are in one-to-one correspondence with the light sources (200) and enable laser beams generated by the light sources (200) to transmit in parallel, a reflecting plate (23) which is arranged in the shell (20) and used for reflecting the laser processed by the collimating lenses (22) and enabling the laser to be projected on a certain area of the skin of a patient, an ultrasonic sensor (24) which is used for detecting photoacoustic blood sugar signals in subcutaneous tissue liquid to be detected and transmitting the signals to a control element (3), and an adhesive sheet (25) which is fixedly adhered to the skin of the detector;

the control element (3) comprises a microcontroller (30) for controlling the normal operation of the blood sugar detection head (2), and a display screen (31) which is connected with the microcontroller (30) and is used for displaying the analysis result of the blood sugar detection; the power supply provides power for the light source (200), the ultrasonic sensor (24) and the display screen (31).

2. The device for the non-destructive testing of glucose in subcutaneous tissue fluid according to claim 1, wherein a handle (10) is provided at the bottom end of the testing body (1), and a plurality of holding grooves (100) are uniformly provided at one side of the handle (10).

3. The device for the non-destructive testing of glucose in subcutaneous tissue fluid according to claim 2, wherein each of said grasping grooves (100) is provided with an elastic fixing band (101) for fixing the grasping finger of the user, and the side wall of the handle (10) and the palm of the user are provided with an anti-slip rubber ring (102).

4. The device for the nondestructive testing of glucose in subcutaneous tissue fluid as claimed in claim 1, wherein a containing cavity (11) is provided in the testing main body (1), a wire winding roller (110) for winding the power wire between the blood glucose testing head (2) and the control element (3) is vertically provided inside the containing cavity (11), and the rear end of the wire winding roller (110) is connected with the rear wall of the containing cavity (11) through a rotating shaft externally provided with a torsion spring.

5. The device for the nondestructive testing of glucose in subcutaneous tissue fluid according to claim 1, wherein the control unit (3) further comprises a login module (32) for authenticating the identity of the tester, a data analysis and storage module (33) for storing the blood glucose test data of the tester and plotting the change trend of the data into a graph and giving reasonable suggestions according to the change trend, a communication module (34) connected with an external intelligent terminal, and an intelligent monitoring module (35) for monitoring and correcting the use process of the tester and timely prompting correct testing method by voice.

6. The device for the non-destructive testing of glucose in subcutaneous tissue fluid according to claim 1, wherein said control unit (3) further comprises a timer (36) for setting a blood glucose test time, and a voice reminding module (37) connected to said timer (36) and for voice reminding the tester of the blood glucose test, wherein said timer (36) and said voice reminding module (37) are connected to said microcontroller (30).

7. The device for the non-destructive testing of glucose in subcutaneous tissue fluid according to claim 1, wherein said light source (200) is a wavelength tunable pulsed laser.

Technical Field

The invention belongs to the technical field of biomedical detection, and particularly relates to a device for nondestructive detection of glucose in subcutaneous tissue fluid.

Background

Diabetes mellitus is a metabolic disease characterized by hyperglycemia, and the main mechanism of diabetes mellitus is hyperglycemia caused by defects in insulin secretion of a human body or impaired biological action thereof, resulting in chronic damage and dysfunction of various tissues, particularly eyes, kidneys, hearts, blood vessels and nerves. The incidence of diabetes is high, the total number of patients in the last 15 years in China is increased by nearly 3 times, reaches more than 3000 tens of thousands, and is increased at a speed of 1% every year; in the united states, more than 2000 million diabetics are present; in Japan, according to the statistics of 1999, the number of diabetic patients and potential patients reaches 690 ten thousand, and the diabetic patients are easy to cause diabetic ketosis, cardiovascular and cerebrovascular diseases, renal failure, blindness and other complications, and seriously threaten the human health.

At present, no method and specific medicine for completely curing diabetes exist, and only blood sugar value is monitored, and then the dosage is increased or decreased by the blood sugar value so as to stabilize the blood sugar value in vivo. Therefore, accurate detection of blood glucose is crucial for diabetic patients. At present, blood glucose is collected by needling, and then the blood glucose is measured by a biochemical analyzer, although the blood glucose obtained by the method is relatively accurate, huge economic and physical and psychological burdens are brought to the diabetic who has a serious disease and needs to frequently monitor the blood glucose, and the wound surface is difficult to heal by frequently pricking the needle, so that the risk of secondary infection is increased. Therefore, the nondestructive detection of blood sugar is a necessary development trend of the blood sugar monitoring technology of the diabetes in the future.

The existing blood sugar nondestructive detection device is used for detecting by laser with a certain fixed wavelength, has the phenomenon of photoacoustic signal interference generated by characteristic absorption of other components, and cannot meet the requirement of detecting glucose in subcutaneous tissue fluid of a human body; when the detection is carried out, only a certain point is detected, a multi-point detection mode in a certain area does not exist, and the detection result has low accuracy; when the detector drops the device carelessly, the device is easy to break and has short service life because of no buffer element.

Disclosure of Invention

Aiming at the problems, the invention provides the device for nondestructively detecting the glucose in the subcutaneous tissue fluid, which has the advantages of accurate detection, long service life and intelligent integration.

The invention provides a device for nondestructively detecting glucose in subcutaneous tissue fluid, which mainly comprises a detection main body, a blood glucose detection head, a control element and a power supply, wherein the blood glucose detection head is arranged at one end part of the detection main body and is used for detecting the content of the glucose in the subcutaneous tissue fluid of a patient;

the blood sugar detection head comprises a shell, a light source plate, a collimating lens, a reflecting plate, an ultrasonic sensor and an adhesive sheet, wherein the light source plate is obliquely arranged at one corner in the shell, the side wall of the light source plate is provided with a plurality of light source plates for generating laser light sources, the collimating lens corresponds to the light sources one by one and enables laser beams generated by the light sources to be transmitted in parallel, the reflecting plate is arranged in the shell and is used for reflecting laser processed by the collimating lens and enabling the laser to be projected to a certain area on the skin of a patient, the ultrasonic sensor is used for detecting blood sugar photoacoustic signals in subcutaneous tissue fluid to be detected and transmitting the signals;

the control element comprises a microcontroller for controlling the normal operation of the blood sugar detection head and a display screen which is connected with the microcontroller and is used for displaying the analysis result of the blood sugar detection; the power supply provides power for the light source, the ultrasonic sensor and the display screen.

Furthermore, the bottom end of the detection main body is provided with a grab handle, a plurality of holding grooves are uniformly formed in one side of the grab handle, and a detector holds the grab handle by hand and places fingers in different holding grooves according to self habit, so that the comfort of holding operation is improved.

Further, every hold all be equipped with the elastic fixation area that is used for fixed user to grip the finger on the groove, the grab handle lateral wall just is located user's palm department and is equipped with the anti-skidding rubber circle, carries out blood sugar monitoring time measuring when the user, and the finger is placed in holding the groove through elastic fixation area, avoids the user hand slippage when gripping the detection main part through elastic fixation area and anti-skidding rubber circle, shortens the life of device.

Further, be equipped with in the detection main part and hold the chamber, it is equipped with the take-up roll that is used for twining the power cord between blood sugar detection head and the control element perpendicularly to hold intracavity portion, just the take-up roll rear end is equipped with the axis of rotation of torsional spring through the outside and holds the wall connection behind the chamber, when needs carry out blood sugar detection, the person of detecting pulls out blood sugar detection head, and at this moment, power cord pulling axis of rotation rotates the extension and carries out blood sugar detection to the person of detecting, and after the detection finishes, but the power cord automatic winding is on the take-up roll to with blood sugar detection head withdrawal, twine the power cord on the take-up roll through above-mentioned mode, avoid power cord intertwine to be difficult to.

Furthermore, the control element also comprises a login module for authenticating the identity of the detector, a data analysis and storage module for storing the blood sugar detection data of the detector and drawing the change trend of the data into a curve graph and giving reasonable suggestions according to the change trend, a communication module connected with an external intelligent terminal, and an intelligent monitoring module for monitoring and correcting the using process of the detector and prompting correct detection methods in time by voice, the identity of the detector is logged in, and the detection result is drawn into the curve graph after logging in, so that the patient can conveniently and visually know the change trend of the blood sugar of the patient and prevent the disease deterioration, the communication module is connected with a hand-note or a computer of the monitor, the monitor can conveniently monitor the blood sugar condition of the patient in real time, accidents are avoided, and the intelligent monitoring module is convenient for the patient to carry out normal blood sugar detection, the accuracy of detection is improved, and the whole device is intelligently integrated through the process.

Further, the control element still including be used for setting for the time of blood sugar test the timer, with the module is reminded to the pronunciation that the timer is connected and is used for pronunciation to remind the person of examining to carry out blood sugar test, timer, pronunciation are reminded the module and are connected with microcontroller, through the settlement of timer, pronunciation warning module, avoid the person of examining to examine because of forgetting blood sugar test, influence the accuracy of the blood sugar trend that data analysis save module analysis obtained.

Furthermore, the light source is a pulse laser with tunable wavelength, and blood glucose detection is performed by adjusting laser with different wavelengths, so that the phenomenon of photoacoustic signal interference caused by absorption of other component characteristics at a certain fixed wavelength is avoided, and the detection of glucose in subcutaneous tissue fluid of a human body cannot be met.

Furthermore, it is equipped with the buffering component to detect the main part outside, the buffering component is located the buffering cover that detects the main part outer wall, evenly locates including the cover a plurality of cushions of buffering cover outside prevent falling board, one end run through the buffering cover with the buffering prevent falling board connection and the other end and detect the buffer spring of main part outer wall connection, when this device drops to ground, prevent falling board and ground contact and compression buffer spring through the buffering and cushion, avoid detecting the main part and break, cause the wasting of resources.

The working principle of the invention is as follows: when the nondestructive testing device provided by the invention is used for testing glucose in subcutaneous tissue fluid, the specific process is as follows:

(1) setting detection time in advance through a timer, and when the detection time is up, reminding a detector to carry out blood sugar detection through a voice reminding module;

(2) the shell is taken down from the detection main body, the power cord is pulled to enable the winding roll and the rotating shaft to rotate, meanwhile, the torsion spring is compressed, then the adhesive sheet is pasted on the skin of a detector, the detector holds the grab handle with hands, and fingers are placed in the holding groove and fixed through the elastic fixing band;

(3) the tester logs in the intelligent blood glucose monitor through the login module and is connected with an external intelligent terminal through the communication module, so that a guardian can conveniently monitor the blood glucose condition of a patient in real time;

(4) the method comprises the following steps that a light source (200) and an ultrasonic sensor are turned on, the microcontroller controls the light source to project lasers with different wavelengths, the projected lasers are collimated by a collimating lens to be parallel laser beams, then the parallel laser beams are emitted to a pasting sheet through a reflecting plate and finally enter subcutaneous tissue fluid of a human body, the tissue fluid absorbs laser energy and generates ultrasonic waves through heat generation volume expansion caused by the laser energy, at the moment, the ultrasonic sensor receives ultrasonic signals from a detector and transmits the ultrasonic signals to the microcontroller, the microcontroller sends the signals to a data analysis and storage module, the data analysis and storage module stores blood glucose detection data of the detector and draws the change trend of the data into a curve graph, the curve graph is displayed through a display screen, and reasonable suggestions are given according to the change trend;

(5) in the process, if operation is difficult, the intelligent monitoring module can be used for monitoring and correcting the using process of a detector and timely and voice-reminding a correct detection method.

Compared with the prior art, the invention has the beneficial effects that: the invention provides a device for nondestructive detection of glucose in subcutaneous tissue fluid, which is characterized in that a tunable pulse laser is used as a light source, when detection is carried out, a plurality of light sources can be adjusted to simultaneously emit laser with different wavelengths, the phenomenon of photoacoustic signal interference generated by the characteristic absorption of other components on a certain fixed wavelength is avoided, the detection of the glucose in the subcutaneous tissue fluid of a human body cannot be met, and simultaneously, the laser emitted by a plurality of partial light sources in sequence from top to bottom can generate different reflection angles on a reflector, so that a detection area is formed at the detection part of a detector for multi-point detection, the detection efficiency is improved, and the accuracy of a detection result is increased; the elastic fixing band and the anti-slip rubber ring prevent the hand of a user from slipping when the user holds the detection main body, so that the service life of the device is shortened; due to the arrangement of the automatic recovery structure of the winding roller, the power lines are prevented from being wound and difficult to separate from each other, and the normal use of the detection device is prevented from being influenced; through the arrangement of the buffer element, the detection device is prevented from being broken, so that resource waste is avoided; the invention has the advantages of accurate detection, long service life and intelligent integration, and is suitable for mass popularization.

Drawings

FIG. 1 is an external structural view of the present invention;

FIG. 2 is a schematic view of the internal structure of the present invention;

FIG. 3 is an enlarged partial view of the cushioning element of the present invention;

FIG. 4 is a schematic view showing the structure of a blood glucose measuring head according to the present invention;

fig. 5 is an electrical connection diagram of the present invention.

The blood glucose monitoring device comprises a detection main body, a 10-grab handle, a 100-holding groove, a 101-elastic fixing belt, a 102-anti-slip rubber ring, a 11-accommodating cavity, a 110-winding roller, a 12-buffer element, a 120-buffer cover, a 121-buffer anti-falling plate, a 122-buffer spring, a 2-blood glucose detection head, a 20-shell, a 200-light source, a 21-light source plate, a 22-collimating lens, a 23-reflector plate, a 24-ultrasonic sensor, a 25-adhesive sheet, a 3-control element, a 30-microcontroller, a 31-display screen, a 32-login module, a 33-data analysis storage module, a 34-communication module, a 35-intelligent monitoring module, a 36-timer and a 37-voice reminding module, wherein the detection main body is connected with the detection main body through a cable.

Detailed Description

Example (b): as shown in figures 1 and 2, the device for non-destructive testing of glucose in subcutaneous tissue fluid mainly comprises a testing body 1, a blood glucose testing head 2 mounted at one end of the testing body 1 for testing the glucose content in subcutaneous tissue fluid of a patient, a control element 3 arranged in the testing body 1 and connected with the blood glucose testing head 2 through a power line, and a power supply;

the bottom end of the detection main body 1 is provided with a holding handle 10, one side of the holding handle 10 is uniformly provided with 4 holding grooves 100, a detector holds the holding handle 10 and places fingers in different holding grooves 100 according to self-learning, the comfort during holding operation is improved, each holding groove 100 is provided with an elastic fixing band 101 for fixing the holding fingers of a user, the side wall of the holding handle 10 and the palm of the user are provided with an anti-slip rubber ring 102, when the user monitors blood sugar, the fingers are placed in the holding grooves 100 through the elastic fixing bands 101, the hand slippage of the user when holding the detection main body 1 is avoided through the elastic fixing bands 101 and the anti-slip rubber rings 102, the service life of the device is shortened, a containing cavity 11 is arranged in the detection main body 1, a winding roller 110 for winding a power line between the blood sugar detection head 2 and the control element 3 is vertically arranged in the containing cavity 11, and the rear end of the winding roller 110 is connected with the rear wall of, when blood sugar detection is needed, a detector pulls out the blood sugar detection head 2, at the moment, the power cord pulls the rotating shaft to rotate and extend to detect the blood sugar of the detector, after the detection is finished, the power cord can be automatically wound on the winding roll 110, and the blood sugar detection head 2 is withdrawn, the power cord is wound on the winding roll 110 in the above way, the normal use of the detection device is prevented from being influenced by the mutual winding and difficult separation of the power cord, as shown in figure 3, the outside of the detection main body 1 is provided with the buffer element 12, the buffer element 12 comprises a buffer cover 120 covering the outer wall of the detection main body 1, 6 buffer anti-falling plates 121 uniformly arranged outside the buffer cover 120, and a buffer spring 122 with one end penetrating through the buffer cover 120 and connected with the buffer anti-falling plates 121 and the other end connected with the outer wall of the detection main body 1, when the device falls to the ground, the buffer anti-falling plates 121 contact with, the detection main body 1 is prevented from being broken, so that resource waste is avoided;

as shown in fig. 4, the blood sugar test head 2 comprises a housing 20, a light source plate 21 obliquely arranged at one corner in the housing 20 and provided with 4 side walls for generating laser light sources 200, a collimating lens 22 corresponding to the light sources 200 one by one and enabling the laser beams generated by the light sources 200 to transmit in parallel, a reflecting plate 23 arranged in the housing 20 and used for reflecting the laser processed by the collimating lens 22 and enabling the laser to be projected on a certain area of the skin of a patient, an ultrasonic sensor 24 used for detecting blood sugar photoacoustic signals in the subcutaneous tissue fluid to be tested and transmitting the signals to a control element 3, an adhesive sheet 25 adhered and fixed with the skin of the test person, wherein the light source 200 is a pulse laser with tunable wavelength, the blood glucose detection is carried out by adjusting the laser with different wavelengths, so that the phenomenon that photoacoustic signals generated by the characteristic absorption of other components exist on a certain fixed wavelength is avoided, and the detection of the glucose in the subcutaneous tissue fluid of a human body cannot be met;

the control component 3 comprises a microcontroller 30 for controlling the normal operation of the blood sugar test head 2, a display screen 31 connected with the microcontroller 30 and used for displaying the analysis result of blood sugar test, a login module 32 for authenticating the identity of the tester, a data analysis and storage module 33 for storing the blood sugar test data of the tester and drawing the change trend of the data into a curve graph and giving reasonable suggestions according to the change trend, a communication module 34 connected with an external intelligent terminal, an intelligent monitoring module 35 for monitoring and correcting the using process of the tester and prompting correct test method by voice in time, a timer 36 for setting the blood sugar test time, and a voice prompt module 37 connected with the timer 36 and used for prompting the tester to test blood sugar by voice, wherein the microcontroller 30 is a commercially available product and is used for logging in the identity of the tester, after logging in, the detection result is drawn into a curve graph, so that a patient can conveniently and visually know the change trend of the blood sugar of the patient, the disease deterioration is prevented, the communication module 34 is connected with a hand note or a computer of a guardian, the guardian can conveniently monitor the blood sugar condition of the patient in real time, accidents are avoided, the intelligent monitoring module 35 is used for conveniently detecting the normal blood sugar of the patient, the detection accuracy is improved, and the whole device is intelligently integrated through the process; the power supply provides power for the light source 200, the ultrasonic sensor 24, the display screen 31, and the timer 36.

When the nondestructive testing device provided by the invention is used for testing glucose in subcutaneous tissue fluid, the specific process is as follows:

(1) setting detection time in advance through a timer 36, and when the detection time is up, reminding a detector to carry out blood sugar detection through a voice reminding module 37;

(2) taking the casing 20 off the detection body 1, pulling the power cord to make the winding roll 110 and the rotating shaft rotate, compressing the torsion spring at the same time, then adhering the adhesive sheet 25 on the skin of the detector, holding the grip handle 10 by the detector, placing the fingers in the holding groove 100 and fixing through the elastic fixing band 101;

(3) the examiner logs in the system through the login module 32 and is connected with an external intelligent terminal through the communication module 34, so that a monitor can monitor the blood sugar condition of the patient in real time conveniently;

(4) the light source 200 and the ultrasonic sensor 24 are turned on, the microcontroller 30 controls the light source 200 to project lasers with different wavelengths, the projected lasers are collimated by the collimating lens 22 into parallel laser beams, then the parallel laser beams are emitted to the adhesive sheet 25 through the reflector 23 and finally enter subcutaneous tissue fluid of a human body, the tissue fluid absorbs laser energy and generates ultrasonic waves through heat generation volume expansion caused by the laser energy, at the moment, the ultrasonic sensor 24 receives ultrasonic signals from a detector and transmits the ultrasonic signals to the microcontroller 30, the microcontroller 30 sends the signals to the data analysis and storage module 33, the data analysis and storage module 33 stores blood glucose detection data of the detector and draws the change trend of the data into a curve graph, the curve graph is displayed through the display screen 31, and reasonable suggestions are given according to the change trend;

(5) in the above process, if operation is difficult, the intelligent monitoring module 35 can monitor and correct the using process of the examiner and prompt the correct detection method by voice in time.