用于检测动物中的肠屏障衰竭的体外方法
阅读说明:本技术 用于检测动物中的肠屏障衰竭的体外方法 (In vitro method for detecting intestinal barrier failure in animals ) 是由 M·佛卢格尔 S·佩尔泽 F·瑟尔曼 F·梵伊莫塞尔 R·杜卡特耶 E·高森斯 B·德沃 于 2019-02-28 设计创作,主要内容包括:本发明涉及用于检测禽类群体中的肠屏障衰竭的体外方法,该方法包括以下步骤:a)收集来源于禽类群体的合并的粪便样品,以及b)确定所述样品中包含的至少一种蛋白质标志物的量;其中所述至少一种蛋白质标志物包含急性期蛋白或其功能片段或由其组成,并且其中与参考样品相比,所述样品中包含的所述至少一种蛋白质标志物的量的增加表明肠屏障衰竭。(The present invention relates to an in vitro method for detecting intestinal barrier failure in a population of avians, the method comprising the steps of: a) collecting a pooled stool sample derived from a population of birds, and b) determining the amount of at least one protein marker contained in the sample; wherein the at least one protein marker comprises or consists of an acute phase protein or a functional fragment thereof, and wherein an increase in the amount of the at least one protein marker comprised in the sample compared to a reference sample is indicative of intestinal barrier failure.)