阅读说明：本技术 一种核酸反应耗材开关盖机构 (Nucleic acid reaction consumptive material switch lid mechanism ) 是由 苗保刚 赵武军 孙瑶 龚大江 玉智泰 李政 于 2020-07-10 设计创作，主要内容包括：一种核酸反应耗材开关盖机构,它包括第一架构层、第二架构层和第三架构层；第一架构层下方竖直设置有若干导杆一,导杆一的上端与第一架构层相连,导杆一的下端贯穿第二架构层和第三架构层；第二架构层与第三架构层间竖直设置有若干导杆二；导杆二上端贯穿第二架构层,导杆二下端与第三架构层相连；导杆二上套设有弹性组件；第一架构层通过升降装置与第二架构层相连,升降装置用于带动第二架构层沿导杆一上下移动；第二架构层上设置有耗材盖固定机构,耗材盖固定机构用于将耗材盖固定在第二架构层上；第三架构层上设置有耗材主体固定机构,耗材主体固定机构用于限制耗材主体移动。该开关盖机构能够避免人工操作而造成样污染,同时,还能够提高操作效率,减少人工疲劳强度。(A nucleic acid reaction consumable material switch cover mechanism comprises a first framework layer, a second framework layer and a third framework layer; a plurality of first guide rods are vertically arranged below the first framework layer, the upper ends of the first guide rods are connected with the first framework layer, and the lower ends of the first guide rods penetrate through the second framework layer and the third framework layer; a plurality of second guide rods are vertically arranged between the second framework layer and the third framework layer; the upper end of the second guide rod penetrates through the second framework layer, and the lower end of the second guide rod is connected with the third framework layer; the second guide rod is sleeved with an elastic component; the first framework layer is connected with the second framework layer through a lifting device, and the lifting device is used for driving the second framework layer to move up and down along the guide rod I; the second framework layer is provided with a consumable cover fixing mechanism, and the consumable cover fixing mechanism is used for fixing a consumable cover on the second framework layer; be provided with consumptive material main part fixed establishment on the third framework layer, consumptive material main part fixed establishment is used for restricting the removal of consumptive material main part. This switch cover mechanism can avoid manual operation and cause the appearance to pollute, simultaneously, can also improve operating efficiency, reduces artifical fatigue strength.)

1. The utility model provides a nucleic acid reaction consumptive material switch lid mechanism which characterized in that: the structure comprises a first structural layer (14), a second structural layer (18) and a third structural layer (19) which are arranged from top to bottom in sequence; a plurality of guide rods I (20) are vertically arranged below the first framework layer (14), the upper ends of the guide rods I (20) are connected with the first framework layer (14), and the lower ends of the guide rods I (20) penetrate through the second framework layer (18) and the third framework layer (19), so that the second framework layer (18) and the third framework layer (19) can move up and down along the guide rods I (20); the lower end of the guide rod I (20) is provided with a lower guide rod limiting block; the guide rod lower limiting block is positioned below the third framework layer (19); a plurality of second guide rods (27) are vertically arranged between the second framework layer (18) and the third framework layer (19); the upper end of the second guide rod (27) penetrates through the second framework layer (18), the lower end of the second guide rod (27) is connected with the third framework layer (19), a second upper guide rod limiting block is arranged at the upper end of the second guide rod (27), and the second upper guide rod limiting block is positioned above the second framework layer (18); an elastic component (21) is sleeved on the second guide rod (27), and the elastic component (21) is positioned between the second framework layer (18) and the third framework layer (19); the first framework layer (14) is connected with the second framework layer (18) through a lifting device, and the lifting device is used for driving the second framework layer (18) to move up and down along the guide rod I (20);

A consumable cover fixing mechanism is arranged on the second framework layer (18) and used for fixing the consumable cover (2) on the second framework layer (18);

be provided with consumptive material main part fixed establishment on third framework layer (19), consumptive material main part fixed establishment is used for restricting consumptive material main part (1) and removes.

2. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 1, wherein:

the upper end of the guide rod I (20) is connected with the area of the bottom edge-close part of the first framework layer (14), and the lower end of the guide rod I (20) penetrates through the area of the edge-close parts of the second framework layer (18) and the third framework layer (19); the second guide rod (27) is located in the area close to the edge of the second framework layer (18) and the third framework layer (19), the upper end of the second guide rod (27) penetrates through the second framework layer (18), and the lower end of the second guide rod (27) is connected with the third framework layer (19).

3. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 1, wherein: the second framework layer limit stop is sleeved on the second guide rod (27), the second framework layer limit stop is positioned between the second framework layer (18) and the third framework layer (19), and the elastic component (21) is sleeved outside the second framework layer limit stop.

4. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 1, wherein:

The lifting device comprises a screw motor (15) and a screw (16); the screw rod motor (15) is fixedly arranged above or below the first framework layer (14), the upper end of the screw rod (16) is connected with the screw rod motor (15), a screw rod connecting seat (17) is arranged above the second framework layer (18), and the lower end of the screw rod (16) penetrates through the second framework layer (18) and the screw rod connecting seat (17) and is in threaded connection with the screw rod connecting seat (17); or the lower end of the screw rod (16) is in threaded connection with the screw rod connecting seat (17).

5. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 1, wherein:

the consumable cover fixing mechanism comprises a plurality of cover opening strips; each cover opening strip comprises a strip-shaped strip body (23) and a connecting block (23b) arranged at the rear end of the strip body, the strip body (23) and the bottom surface of the second layer of framework layer are arranged at intervals, and the rear end of the strip body (23) is connected with the bottom surface of the second framework layer (18) through the connecting block (23 b);

the cover opening strips are arranged in a row in parallel at equal intervals, so that consumable cover clamping grooves (22) with bottom openings and front end openings are formed at intervals between every two adjacent cover opening strips.

6. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 5, wherein: the front end of the strip body (23) is provided with an uncovering bulge (23 a).

7. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 6, wherein: the cover opening bulge (23a) is positioned above the strip body (23), and the cover opening bulge (23a) comprises a prying cover part and a limiting part; the pry cover part is positioned at the front end of the cover opening bulge (23a), the limiting part is positioned at the rear end of the cover opening bulge (23a), and the front end of the strip body (23) is connected with the lower part of the limiting part.

8. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 7, wherein: the length of the strip body (23) is more than or equal to that of the consumable cover (2).

9. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 1 or 8, wherein: the consumable main body fixing mechanisms are a plurality of consumable main body fixing grooves (24) formed in the third framework layer (19), and the consumable main body fixing grooves (24) are arranged in parallel at equal intervals in a row and penetrate through the third framework layer (19) in the vertical direction; the front end of the consumable body fixing groove (24) is opened.

10. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 9, wherein: the length of the consumable body fixing groove is more than or equal to that of the consumable body (1).

11. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 9, wherein: the extending direction of the consumable body fixing groove (24) is consistent with the extending direction of the consumable cover clamping groove (22); the number of the consumable body fixing grooves (24) corresponds to the number of the consumable cover clamping grooves (22) and is aligned with the consumable cover clamping grooves (22).

12. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 1, wherein: and a consumable loading platform connecting piece is arranged at the bottom of the third framework layer (19), and is used for detachably connecting the third framework layer (19) and the consumable loading platform (10).

13. The consumable opening and closing cap mechanism for nucleic acid reaction according to claim 12, wherein: the connecting piece of the consumable loading table is a fixing strip (25) arranged at the bottom of the third framework layer (19), a clamping interface (26) is arranged on the fixing strip (25), the clamping interface (26) is used for enabling a fixing bolt (13) arranged on the side wall of the consumable loading table (10) to be embedded into the clamping interface (26) from the horizontal direction, and the third framework layer (19) and the consumable loading table (10) are limited to be separated from each other from top to bottom.

Technical Field

The invention relates to the field of instrument automation, in particular to a consumable opening and closing cover mechanism for nucleic acid reaction.

Background

Nucleic acids are carriers of genetic information in organisms, and isolation, purification, and detection of nucleic acids are required for studies on nucleic acid sequences and structures, or for the search for gene functions and expression.

With the advancement of technology, the automation of nucleic acid extraction and detection equipment will be a necessary trend. However, the fully automatic nucleic acid detection should not be limited to the automation of the nucleic acid extraction and detection processes, but also include the steps of adding the sample, transferring the product, disposing the waste, etc., so as to minimize the contact between the operator and the sample, the reagent, the reaction product, and the waste consumable, and reduce the risks of biological contamination and biohazard.

The existing nucleic acid reaction consumable comprises a consumable body and a consumable cover, the uncovering and covering operations of the existing nucleic acid reaction consumable are all completed by manual operation, the risk that a sample is polluted can be increased, meanwhile, the manual operation efficiency is low, and the manual fatigue strength is high.

Therefore, it is necessary to design a cap opening and closing mechanism for the operation of opening and closing the cap of the consumable for nucleic acid reaction instead of manual operation.

Disclosure of Invention

The invention aims to: to the problem that above-mentioned exists, provide a nucleic acid reaction consumptive material switch lid mechanism, it can avoid manual operation and cause kind to pollute, simultaneously, can also improve operating efficiency, reduce artifical fatigue strength.

The technical scheme adopted by the invention is as follows:

a nucleic acid reaction consumable material cover opening and closing mechanism comprises a first framework layer, a second framework layer and a third framework layer which are sequentially arranged from top to bottom; a plurality of first guide rods are vertically arranged below the first framework layer, the upper ends of the first guide rods are connected with the first framework layer, and the lower ends of the first guide rods penetrate through the second framework layer and the third framework layer, so that the second framework layer and the third framework layer can move up and down along the first guide rods; a lower guide rod limiting block is arranged at the lower end of the first guide rod; the guide rod lower limiting block is positioned below the third framework layer; a plurality of guide rods II are vertically arranged between the second framework layer and the third framework layer; the upper end of the second guide rod penetrates through the second framework layer, the lower end of the second guide rod is connected with the third framework layer, the upper end of the second guide rod is provided with a second upper limiting block of the guide rod, and the second upper limiting block of the guide rod is positioned above the second framework layer; an elastic component is sleeved on the second guide rod and is positioned between the second framework layer and the third framework layer; the first framework layer is connected with the second framework layer through a lifting device, and the lifting device is used for driving the second framework layer to move up and down along the guide rod I;

The second framework layer is provided with a consumable cover fixing mechanism, and the consumable cover fixing mechanism is used for fixing a consumable cover on the second framework layer;

be provided with consumptive material main part fixed establishment on the third framework layer, consumptive material main part fixed establishment is used for restricting the removal of consumptive material main part.

Due to the structure, when the lifting device pushes the second framework layer to move downwards, the third framework layer also moves downwards, and when the third framework layer reaches the limit position, the second framework layer continues to move downwards, so that the elastic component is compressed to apply a downward pushing force to the third framework layer; at this moment, when the consumable main body fixing mechanism on the third framework layer fixes the consumable main body, when the consumable cover fixing mechanism on the second framework layer fixes the consumable cover, the lifting device drives the second framework layer to move upwards for a short distance, so that the consumable cover moves upwards, the elastic component is still in a compression state at this moment, then the third framework layer provides a downward force for the consumable main body, the second framework layer provides an upward force for the consumable cover, the consumable cover and the consumable main body can be separated, the cover opening purpose is reached, when the cover is closed, then only the lifting device is needed to drive the second framework layer to move downwards. The mechanism can be used for conveniently opening and closing the cover of the nucleic acid reaction consumable.

Furthermore, the upper end of the guide rod is connected with the area of the bottom edge-leaning part of the first framework layer, and the lower end of the guide rod penetrates through the areas of the edge-leaning parts of the second framework layer and the third framework layer; the second guide rod is positioned in the area close to the edge of the second framework layer and the third framework layer, the upper end of the second guide rod penetrates through the second framework layer, and the lower end of the second guide rod is connected with the third framework layer.

Due to the structure, the plurality of guide rods I are arranged among the first framework layer, the second framework layer and the third framework layer, so that the stability of the structure can be ensured, and the situation that the first framework layer, the second framework layer and the third framework layer can rotate around the guide rods under the condition that only one guide rod I is arranged is avoided; meanwhile, the first guide rod and the second guide rod are respectively positioned in the edge regions of the first framework layer, the second framework layer and the third framework layer, so that the middle regions of the first framework layer, the second framework layer and the third framework layer are reserved conveniently, and the middle regions of the first framework layer, the second framework layer and the third framework layer are used as operating spaces or operating equipment for opening and closing covers.

Furthermore, a second framework layer limit stop is sleeved on the second guide rod, the second framework layer limit stop is positioned between the second framework layer and the third framework layer, and the elastic assembly is sleeved outside the second framework layer limit stop.

Due to the structure, when the cover is closed, the limit stop of the second framework layer is matched with the elastic component, so that the second framework layer can be prevented from moving downwards to be transited, and the limit stop and the third framework layer are hard to touch, and the equipment is prevented from being damaged.

Further, the lifting device comprises a screw motor and a screw; the screw rod motor is fixedly arranged above or below the first framework layer, the upper end of the screw rod is connected with the screw rod motor, a screw rod connecting seat is arranged above the second framework layer, and the lower end of the screw rod penetrates through the second framework layer and the screw rod connecting seat and is in threaded connection with the screw rod connecting seat; or the lower end of the screw rod is in threaded connection with the screw rod connecting seat.

Because above-mentioned structure, as elevating gear through screw mechanism, the control of the lift distance of being convenient for, simultaneously, the lead screw has the auto-lock characteristic, avoids the second framework layer to appear sliding in the course of the work, guarantees the stability of work.

Furthermore, the consumable cover fixing mechanism comprises a plurality of cover opening strips; each cover opening strip comprises a strip-shaped strip body and a connecting block arranged at the rear end of the strip body, the strip body and the bottom surface of the second framework layer are arranged at intervals, and the rear end of the strip body is connected with the bottom surface of the second framework layer through the connecting block;

The cover opening strips are arranged in a row in parallel at equal intervals, so that the intervals between every two adjacent cover opening strips form consumable cover clamping grooves with bottom openings and front end openings.

Because above-mentioned structure, when the consumptive material lid got into consumptive material lid draw-in groove from consumptive material lid draw-in groove front end opening, both sides about the pipe cover board just alright block under the effect of consumptive material lid draw-in groove, fixed the consumptive material lid on second framework layer, and then alright follow second framework layer and remove.

Furthermore, the front end of the strip body is provided with a cover opening bulge.

Further, the cover opening bulge is positioned above the strip body and comprises a prying cover part and a limiting part; the pry cover part is positioned at the front end of the cover opening bulge, the limiting part is positioned at the rear end of the cover opening bulge, and the front end of the strip body is connected with the lower part of the limiting part.

Due to the structure, the prying cover part can be conveniently inserted into a gap between the consumable cover and the consumable main body, so that the consumable cover can more easily enter the consumable cover clamping groove; when the consumptive material lid is whole to get into consumptive material lid draw-in groove, spacing portion can avoid the consumptive material lid to follow consumptive material lid draw-in groove front end roll-off.

Further, the length of the strip body is more than or equal to that of the consumable cover.

Can make consumptive material lid can partly get into consumptive material lid draw-in groove like this, simultaneously, when the length of the strip body slightly is greater than the length of consumptive material lid, the consumptive material lid just is located between connecting block and the spacing portion, avoids the consumptive material lid to slide, makes things convenient for the location of follow-up closing the lid operation like this.

Furthermore, the consumable main body fixing mechanisms are a plurality of consumable main body fixing grooves which are formed in the third framework layer, are arranged in a row at equal intervals in parallel and penetrate through the third framework layer in the vertical direction; the consumable main body fixing groove is opened at the front end.

Because above-mentioned structure, in the body upper end that the consumptive material main part was in the convenient consumptive material main part got into the fixed slot from fixed slot front end opening for the consumptive material front end opening, when the whole embedding consumptive material main part fixed slots in body upper end in the consumptive material main part, the connecting plate of consumptive material main part can be pushed down to consumptive material main part fixed slot lower limb, is opening the lid in-process fixed consumptive material main part.

Furthermore, the length of the consumable body fixing groove is more than or equal to that of the consumable body.

Furthermore, the extending direction of the consumable body fixing groove is consistent with the extending direction of the consumable cover clamping groove; the quantity of consumptive material main part fixed slot corresponds with the quantity of consumptive material lid draw-in groove to align with consumptive material lid draw-in groove.

Furthermore, a consumable loading platform connecting piece is arranged at the bottom of the third framework layer and used for detachably connecting the third framework layer with the consumable loading platform.

Present consumptive material is mostly placed on the consumptive material loading platform, therefore, the position relatively fixed that can guarantee consumptive material loading platform and third framework layer is connected through consumptive material loading platform connecting piece to third framework layer and consumptive material loading platform, make the third framework lamination on the consumptive material main part, avoid the consumptive material loading platform to take place the displacement in the work simultaneously, also be convenient for consumptive material main part fixed establishment and consumptive material loading platform cooperation simultaneously, with the stable fixing of consumptive material on the consumptive material loading platform, be convenient for subsequent switch lid operation.

Further, the connecting piece of the consumable loading platform is a fixing strip arranged at the bottom of the third framework layer, a clamping interface is arranged on the fixing strip, and the clamping interface is used for enabling a fixing bolt arranged on the side wall of the consumable loading platform to be embedded into the clamping interface in the horizontal direction and limiting the vertical separation of the third framework layer and the consumable loading platform.

Due to the structure, the third framework layer and the consumable loading platform can be quickly connected and separated in the clamping mode.

In summary, due to the adoption of the technical scheme, the invention has the beneficial effects that:

the cover opening and closing mechanism can conveniently open and close the nucleic acid reaction consumables, avoid biological pollution caused by manual operation, improve the cover opening and closing efficiency, operate a plurality of consumables in batch at one time, and reduce the manual fatigue strength.

Drawings

FIG. 1 is a structural diagram of consumables for nucleic acid reaction in example 2;

FIG. 2 is a schematic diagram of the lid opening and closing mechanism and the consumable loading station;

FIG. 3 is a block diagram of a consumable loading station;

FIG. 4 is an overall structural view of the opening and closing cover mechanism;

FIG. 5 is a block diagram of a second structural layer;

FIG. 6 is a block diagram of a cover strip;

FIG. 7 is a block diagram of a third structural layer;

FIGS. 8-15 are state diagrams of the uncapping process;

fig. 16-20 are state diagrams of the closing process.

Detailed Description

The present invention will be described in detail below with reference to the accompanying drawings.

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.