阅读说明：本技术 一种高效氯氟氰菊酯纳米水剂及其制备方法和应用 (Efficient cyhalothrin nano water aqua and preparation method and application thereof ) 是由 陈叶青 张宝俊 杨琴 白杰 洪鹏 于 2019-11-12 设计创作，主要内容包括：本发明属于农药技术领域,公开了一种高效氯氟氰菊酯纳米水剂,该纳米水剂以高效氯氟氰菊酯、表面活性剂和水为原料,不添加任何有机溶剂,采用表面活性剂胶束增溶方法制成的；其中,高效氯氟氰菊酯质量百分含量0.5-10%,表面活性剂5-20%,余量为水。本发明采用表面活性剂胶束增溶方法制成纳米水剂,与常规农药剂型相比,具有优异的稳定性,分别在0℃冷贮7d和54℃热贮14d后仍然稳定,高效氯氟氰菊酯纳米水剂不会析出,便于贮藏,货架期更长；本发明纳米水剂具有较低的生产成本和更优异的速效性和持效性,不会出现药害等不良反应,更适合无人机用药。(The invention belongs to the technical field of pesticides, and discloses a high-efficiency cyhalothrin nano-water agent which is prepared by taking high-efficiency cyhalothrin, a surfactant and water as raw materials, adding no organic solvent and adopting a surfactant micelle solubilization method; wherein, the mass percentage content of the high-efficiency cyhalothrin is 0.5 to 10 percent, the mass percentage content of the surfactant is 5 to 20 percent, and the balance is water. Compared with the conventional pesticide formulation, the nano water agent prepared by adopting the surfactant micelle solubilization method has excellent stability, is still stable after being respectively stored at 0 ℃ for 7 days and at 54 ℃ for 14 days, is not separated out, is convenient to store and has longer shelf life; the nano water aqua has lower production cost, more excellent quick action and persistence, does not have adverse reactions such as phytotoxicity and the like, and is more suitable for unmanned aerial vehicles.)

1. The efficient cyhalothrin nano-water agent is characterized in that the nano-water agent is prepared by taking efficient cyhalothrin, a surfactant and water as raw materials and adopting a surfactant micelle solubilization method; wherein the nano water agent contains 0.5-10% of efficient cyhalothrin, 5-20% of surfactant and the balance of water.

2. The lambda-cyhalothrin nano-water aqua according to claim 1, which is characterized in that the content of the lambda-cyhalothrin is 1-5% by mass.

3. The lambda-cyhalothrin nano-water aqua according to claim 1, wherein the surfactant is selected from any 1 or more of fatty alcohol polyoxyethylene ether, alkylphenol formaldehyde resin polyoxyethylene ether, styrylphenol polyoxyethylene ether, tristyrylphenol polyoxyethylene ether phosphate, fatty alcohol polyoxyethylene ether phosphate, alkylphenol polyoxyethylene ether phosphate and sodium fatty acid methyl ester sulfonate.

4. The preparation method of the lambda-cyhalothrin nano-water aqua according to claim 1, which is characterized in that the lambda-cyhalothrin is mixed with a surfactant, water is added, and the mixture is stirred to form a surfactant micelle solution, namely the lambda-cyhalothrin nano-water aqua.

5. The preparation method of lambda-cyhalothrin nano-water aqua according to claim 4, which is characterized by comprising the following steps:

mixing and stirring the efficient cyhalothrin and the surfactant at normal temperature to uniformly disperse the efficient cyhalothrin in the surfactant;

and (2) adding water, and continuously and uniformly stirring to form a surfactant micelle solution, namely the nano water agent containing the efficient cyhalothrin.

6. The method for preparing lambda-cyhalothrin nano water aqua according to claim 5, characterized in that in the step (1) and the step (2), the stirring speed is 60-100 revolutions per second.

Technical Field

The invention belongs to the technical field of production and processing of pesticides, and particularly relates to a lambda-cyhalothrin nano-water aqua and a preparation method and application thereof.

Background

The Cyhalothrin (Cyhalothrin) can be widely used for controlling pests such as aphids, armyworms, diamondback moths, cabbage caterpillars, oriental tobacco budworms, corn bollworms, pink bollworms, peach plantlets, oriental fruit moths, citrus leaf miners, tea caterpillars, tea loopers, tea leafhoppers and the like on crops such as wheat, rape, vegetables, cotton, fruit trees, tea leaves, tobacco and the like.

The efficient cyhalothrin is insoluble in water, and the pesticide formulations developed by taking the efficient cyhalothrin as a raw material at present mainly comprise missible oil, emulsion in water and the like. However, both missible oil and emulsion in water contain a large amount of organic solvent, and in the using process, the organic solvent not only can cause serious harm to the environment, but also can seriously affect the quality of agricultural products, accelerate the food safety crisis and harm human health.

With the increasing environmental awareness of users and the rapidly growing demand for sanitary medicine, the existing dosage forms of lambda-cyhalothrin cannot meet the use demand. In order to accelerate the popularization and the use of the efficient cyhalothrin product on the premise of safety and environmental protection, it is particularly necessary to develop a novel preparation which is friendly to people and livestock and is convenient for the application of aerial plant protection technologies and equipment such as unmanned aerial vehicles and the like.

Disclosure of Invention

Aiming at the defects of the existing problems, the invention provides a high-efficiency cyhalothrin nano water aqua and a preparation method and application thereof; the invention creatively discovers that a novel nano water aqua is formed by adopting certain surfactants, adopting a surfactant micelle solubilization technology and utilizing the nano micelle formed by the surfactants to bear the water-insoluble pesticide component, namely the high-efficiency cyhalothrin under the condition of not using an organic solvent for solubilizing.

The purpose of the invention can be realized by the following technical scheme:

the efficient cyhalothrin nano-water agent is prepared by taking efficient cyhalothrin, a surfactant and water as raw materials, does not contain any organic solvent and adopting a surfactant micelle solubilization method, wherein the efficient cyhalothrin in the nano-water agent accounts for 0.5-10% by mass, the surfactant accounts for 5-20% by mass and the balance of water

Preferably, the efficient cyhalothrin comprises, by mass, 1-5% of the efficient cyhalothrin, 5-20% of the surfactant and the balance of water.

The surfactant is selected from 1 or more of fatty alcohol-polyoxyethylene ether, alkylphenol formaldehyde resin polyoxyethylene ether, styryl phenol polyoxyethylene ether, tristyryl phenol polyoxyethylene ether phosphate, fatty alcohol-polyoxyethylene ether phosphate, alkylphenol polyoxyethylene ether phosphate, fatty alcohol-polyoxyethylene ether sodium sulfate and fatty acid methyl ester sodium sulfonate.

Preferably, the number of the surfactants is 1 to 4.

The efficient cyhalothrin nano-water aqua with good stability and better drug effect is obtained by compounding or singly using the nonionic surfactant, the anionic surfactant and the like and then compounding the effective component cyhalothrin.

Preferably, the efficient cyhalothrin can be independently prepared into a nano water aqua for use, and can also be compounded with other deinsectization mite removal medicaments to be prepared into the nano water aqua for use by selecting a proper surfactant.

The invention also aims to provide a preparation method of the lambda-cyhalothrin nano-water aqua.

Specifically, the preparation method of the lambda-cyhalothrin nano water agent comprises the following steps:

mixing and stirring the efficient cyhalothrin and the surfactant at normal temperature (10-35 ℃) to uniformly disperse the efficient cyhalothrin in the surfactant;

and (2) adding water, and uniformly stirring to form a surfactant micelle solution, namely the efficient cyhalothrin nano-water aqua.

Preferably, in the step (1), the stirring speed is adjusted according to actual conditions, so that the beta-cypermethrin is uniformly dispersed in the surfactant.

Preferably, in the step (1), the stirring speed is 60-100 revolutions per second, the stirring time is generally 0.5h, and the time can be adjusted by a technician so that the efficient cyhalothrin is uniformly dispersed in the surfactant.

Preferably, in the step (2), the stirring speed is adjusted according to actual conditions, so as to form the surfactant micelle solution by uniformly stirring.

Preferably, in the step (2), the stirring speed is 60-100 rpm/s, and the stirring time is 0.5-1 h.

The efficient cyhalothrin nano-water aqua is used for controlling pests such as aphids, armyworms, diamondback moths, cabbage caterpillars, oriental tobacco budworms, corn bollworms, pink bollworms, peach plantlets, oriental fruit moths, citrus leaf miners, tea caterpillars, tea plant hoppers, tea leafhoppers and the like on crops such as wheat, rapes, vegetables, cotton, fruit trees, tea leaves, tobacco and the like.

Different from the conventional pesticide aqueous solution, the active ingredients in the nano aqueous solution are insoluble in water and can not form a true solution, but are coated by nano-scale surfactant micelles and uniformly dispersed in water to form the true solution.

The nano water agent containing the efficient cyhalothrin is transparent and colorless in appearance, and the average particle size of the surfactant micelle is in a nano level; after entering water, the water-soluble polymer can be quickly dissolved with water to form a completely transparent solution, and the dilution stability is qualified.

Compared with the prior art, the invention has the beneficial effects that:

1. the efficient cyhalothrin nano water aqua disclosed by the invention does not contain any organic solvent, is safe and environment-friendly, belongs to an environment-friendly formulation, is suitable for agricultural medication, is suitable for the requirement of sanitary medication, and can be widely applied to the fields of agriculture, families and public health.

2. Because the active ingredients are carried by the nano micelle, the invention can form true solution, the preparation is more stable, the preparation is still stable after being stored at 0 ℃ for 7 days and stored at 54 ℃ for 14 days, the high-efficiency cyhalothrin can not be separated out, the storage is convenient, and the shelf life is longer.

3. The invention is a nanometer preparation product, has extremely small medicine fineness, no particle precipitation and better medicine effect, and is more suitable for the unmanned aerial vehicle pesticide application technology.

4. The nano water aqua has excellent quick action and persistence, and adverse reactions such as phytotoxicity and the like can not occur.

5. The efficient cyhalothrin nano water aqua has the advantages of low production cost, simple preparation process and good economy.

Drawings

FIG. 1 shows the 4.5% aqueous solution of lambda-cyhalothrin prepared in example 8 after standing at low temperature (0 deg.C) for 1-2 days and then heating to room temperature.

FIG. 2 shows the situation of 4.5% of lambda-cyhalothrin aqueous solution prepared in comparative example 4 at room temperature after being placed at low temperature (0 deg.C) for 1-2 days and then heated to room temperature.

Detailed Description

The present invention will be described in further detail with reference to examples. The reagents or instruments used are not indicated by manufacturers, and are regarded as conventional products which can be purchased in the market.

The method for detecting the particle size of the nano water agent comprises the following steps:

the particle size of the surfactant micelle in the pesticide Nano water agent is measured by a Marvens high-sensitivity Nano particle size analyzer Zetasizer Nano S (25 ℃).