阅读说明：本技术 一种医疗美容抗菌义齿基托材料及其制备方法 (Medical beauty antibacterial denture base material and preparation method thereof ) 是由 陈坚 刘玉德 于 2020-07-31 设计创作，主要内容包括：本发明公开了一种医疗美容抗菌义齿基托材料及其制备方法,涉及医疗美容抗菌义齿基托材料制备技术领域,包括以下步骤：步骤A,制备基料；步骤B,加强料混合；步骤C,抑菌抗菌配比填料；步骤D,均匀混融加工；步骤E,制备基托；步骤F,脱模处理。本发明通过聚甲基丙烯酸甲酯和丙烯酸树脂作为基本材料,使义齿基托的生产成本大大降低,降低使用者的经济负担,同时通过抑菌剂甲壳胺纤维和抗菌剂纳米二氧化钛载银抗菌剂,一方面保持基托的硬度,另一方面对口腔的细菌增殖产生抑制作用,能抑制细菌在基托表面的粘附,进而提高义齿基托的抗菌抑菌效果,纳米二氧化钛载银抗菌剂具备耐热稳定,化学稳定性好,能杀灭细菌、病毒。(The invention discloses a medical beauty antibacterial denture base material and a preparation method thereof, relating to the technical field of preparation of the medical beauty antibacterial denture base material and comprising the following steps: step A, preparing a base material; b, mixing the reinforcing materials; step C, preparing fillers in an antibacterial and antibacterial ratio; step D, uniformly mixing and melting; step E, preparing a base; and F, demolding. According to the invention, polymethyl methacrylate and acrylic resin are used as basic materials, so that the production cost of the denture base is greatly reduced, the economic burden of a user is reduced, meanwhile, the bacteriostatic agent chitosan fiber and the antibacterial agent nano titanium dioxide silver-carrying antibacterial agent are used for keeping the hardness of the denture base on one hand and generating an inhibiting effect on the bacterial proliferation of the oral cavity on the other hand, so that the adhesion of bacteria on the surface of the denture base can be inhibited, the antibacterial and bacteriostatic effects of the denture base are further improved, and the nano titanium dioxide silver-carrying antibacterial agent has the advantages of heat resistance, stability, good chemical stability and capability of killing bacteria and viruses.)

1. A medical cosmetic antibacterial denture base material is characterized by comprising the following components (by mass percent): 20-40 parts of acrylic resin, 40-50 parts of polymethyl methacrylate, 2-4 parts of a first reinforcing agent, 0.8-1.6 parts of a second reinforcing agent, 4-8 parts of a binder, 25-35 parts of deionized water, 0.5-0.7 part of a dispersing agent, 8-12 parts of a bacteriostatic agent and 6-10 parts of an antibacterial agent.

2. A medical cosmetic antibacterial denture base material according to claim 1, wherein: comprises the following components (by mass percent): 20 parts of acrylic resin, 50 parts of polymethyl methacrylate, 2 parts of a first reinforcing agent, 0.8 part of a second reinforcing agent, 4 parts of an adhesive, 25 parts of deionized water, 0.5 part of a dispersing agent, 8 parts of a bacteriostatic agent and 6 parts of an antibacterial agent.

3. A medical cosmetic antibacterial denture base material according to claim 1, wherein: comprises the following components (by mass percent): 30 parts of acrylic resin, 45 parts of polymethyl methacrylate, 3 parts of a first reinforcing agent, 1 part of a second reinforcing agent, 6 parts of an adhesive, 30 parts of deionized water, 0.6 part of a dispersing agent, 10 parts of a bacteriostatic agent and 10 parts of an antibacterial agent.

4. A medical cosmetic antibacterial denture base material according to claim 1, wherein: comprises the following components (by mass percent): 40 parts of acrylic resin, 40 parts of polymethyl methacrylate, 4 parts of a first reinforcing agent, 1.6 parts of a second reinforcing agent, 7 parts of an adhesive, 35 parts of deionized water, 0.7 part of a dispersing agent, 12 parts of a bacteriostatic agent and 10 parts of an antibacterial agent.

5. A medical cosmetic antibacterial denture base material according to claim 1, wherein: comprises the following components (by mass percent): 40 parts of acrylic resin, 50 parts of polymethyl methacrylate, 4 parts of a first reinforcing agent, 1.5 parts of a second reinforcing agent, 8 parts of an adhesive, 35 parts of deionized water, 0.7 part of a dispersing agent, 10 parts of a bacteriostatic agent and 10 parts of an antibacterial agent.

6. A medical cosmetic antibacterial denture base material according to claim 1, wherein:

the first reinforcing agent is chromium oxide, and the second reinforcing agent is lead-free boron carbide ceramic;

the bacteriostatic agent is chitosan fiber, and the antibacterial agent is a nano titanium dioxide silver-loaded antibacterial agent.

7. A medical cosmetic antibacterial denture base material according to claim 1, wherein:

the adhesive is polyvinyl acetate, and the dispersing agent is polyvinyl alcohol.

8. The method for preparing a medical cosmetic antibacterial denture base material according to claim 1, which comprises the following steps:

a: preparing a base material, namely firstly putting polymethyl methacrylate into a crusher for crushing, then crushing the crushed polymethyl methacrylate into powder by a ball mill, after sieving, putting the polymethyl methacrylate powder into a stirrer with a heating and heat-insulating function, simultaneously adding acrylic resin, stirring for 12-15 min at the speed of 150-180 r/min, and uniformly mixing the acrylic resin and the polymethyl methacrylate to prepare the denture base material;

b: mixing reinforcing materials, namely putting a first reinforcing agent and a second reinforcing agent into a denture base material, heating to 67-85 ℃, stirring at the speed of 170-200 r/min for 10-14 min, and mixing the first reinforcing agent and the second reinforcing agent with the denture base material to prepare a reinforcing mixture;

c: adding a bacteriostatic agent and an antibacterial agent into a ball mill, blending the bacteriostatic agent and the antibacterial agent by the ball mill to prepare a bacteriostatic and antibacterial mixed material, adding the bacteriostatic and antibacterial mixed material into a reinforced mixed material, heating the mixed material to 30-50 ℃, mixing the reinforced mixed material and the bacteriostatic and antibacterial mixed material by a stirrer at the rotating speed of 170-200 r/min for 3-5 min to prepare a bacteriostatic and antibacterial reinforced mixed material;

d: uniformly mixing and melting, pouring deionized water into the antibacterial and antibacterial reinforced mixture, keeping the heating temperature at 20-30 ℃, then putting a dispersing agent into the antibacterial and antibacterial reinforced mixture, uniformly stirring at the speed of 180-220 r/min for 4-6 min, then adding an adhesive, uniformly stirring at the speed of 180-220 r/min for 7-10 min, and standing the antibacterial and antibacterial reinforced mixture for 2-4 h to enable the antibacterial and antibacterial reinforced mixture to naturally precipitate;

e: preparing a base, namely putting a naturally precipitated antibacterial and antibacterial reinforced mixture into a base reactor, uniformly suspending materials in the antibacterial and antibacterial reinforced mixture through ultrasonic dispersion, then putting the suspended materials into a base mold, heating the base mold to 75-85 ℃, heating for 12-24 min to gradually agglomerate the suspended materials, then heating to 90-98 ℃, and heating at constant temperature for 45-70 min to prepare a curing base;

f: and (3) demolding, namely separating the cured base support from the mold, standing to reduce the temperature to normal temperature, then sequentially performing coarse grinding and fine grinding on the surface of the base support to smooth the surface of the base support, then soaking the base support in distilled water at 65-80 ℃ for 10-30 s, and then drying the surface of the base support through a high-pressure air gun.

9. The method for preparing a medical cosmetic antibacterial denture base material according to claim 8, wherein:

in the step A, the polymethyl methacrylate crushed aggregates are sieved by a sieve with 70-90 meshes.

10. The method for preparing a medical cosmetic antibacterial denture base material according to claim 8, wherein:

in the step D, after the antibacterial and antibacterial reinforced mixture is stood still, 2-4 parts of preservative (by mass percentage) are added, and the mixture is uniformly stirred at the speed of 180-200 r/min for 3-5 min.

Technical Field

The invention relates to the technical field of preparation of medical beauty antibacterial denture base materials, in particular to a medical beauty antibacterial denture base material and a preparation method thereof.

Background

The denture is a general term for a prosthesis made after partial or all teeth of the upper and lower jaws are lost in medicine. The artificial tooth is divided into removable type and fixed type. The fixed denture can not be taken by a patient, the removable denture, namely the movable denture, can be taken by the patient conveniently, the denture base belongs to one part of the removable partial denture, so that the artificial tooth is connected with the denture, the mechanical performance of the denture base usually determines the use comfort of the user, on the other hand, the existing denture base has higher production cost, the bacteriostatic and antibacterial effects of the denture base also usually determine the diet health problem of the user, and the symptoms of bacteria breeding or inflammation in the oral cavity seriously affect the oral health and daily life of the user, and in addition.

Therefore, it is necessary to invent a medical cosmetic antibacterial denture base material and a preparation method thereof to solve the above problems.

Disclosure of Invention

Technical problem to be solved

Aiming at the defects of the prior art, the invention provides a medical beauty antibacterial denture base material and a preparation method thereof, and solves the problems that the prior denture base has poor comfort stability and high industrial production cost, the food health of a user is influenced due to the poor antibacterial effect of the denture base, and oral bacteria are easy to breed in a large amount or cause oral inflammation, so that the oral health and daily life of the user are seriously influenced.

(II) technical scheme

In order to achieve the purpose, the invention is realized by the following technical scheme:

a medical and cosmetic antibacterial denture base material comprises the following components (by mass percent): 20-40 parts of acrylic resin, 40-50 parts of polymethyl methacrylate, 2-4 parts of a first reinforcing agent, 0.8-1.6 parts of a second reinforcing agent, 4-8 parts of a binder, 25-35 parts of deionized water, 0.5-0.7 part of a dispersing agent, 8-12 parts of a bacteriostatic agent and 6-10 parts of an antibacterial agent.

Optionally, the composition comprises the following components (in percentage by mass): 20 parts of acrylic resin, 50 parts of polymethyl methacrylate, 2 parts of a first reinforcing agent, 0.8 part of a second reinforcing agent, 4 parts of an adhesive, 25 parts of deionized water, 0.5 part of a dispersing agent, 8 parts of a bacteriostatic agent and 6 parts of an antibacterial agent.

Optionally, the composition comprises the following components (in percentage by mass): 30 parts of acrylic resin, 45 parts of polymethyl methacrylate, 3 parts of a first reinforcing agent, 1 part of a second reinforcing agent, 6 parts of an adhesive, 30 parts of deionized water, 0.6 part of a dispersing agent, 10 parts of a bacteriostatic agent and 10 parts of an antibacterial agent.

Optionally, the composition comprises the following components (in percentage by mass): 40 parts of acrylic resin, 40 parts of polymethyl methacrylate, 4 parts of a first reinforcing agent, 1.6 parts of a second reinforcing agent, 7 parts of an adhesive, 35 parts of deionized water, 0.7 part of a dispersing agent, 12 parts of a bacteriostatic agent and 10 parts of an antibacterial agent.

Optionally, the composition comprises the following components (in percentage by mass): 40 parts of acrylic resin, 50 parts of polymethyl methacrylate, 4 parts of a first reinforcing agent, 1.5 parts of a second reinforcing agent, 8 parts of an adhesive, 35 parts of deionized water, 0.7 part of a dispersing agent, 10 parts of a bacteriostatic agent and 10 parts of an antibacterial agent.

Alternatively to this, the first and second parts may,

the first reinforcing agent is chromium oxide, and the second reinforcing agent is lead-free boron carbide ceramic;

the bacteriostatic agent is chitosan fiber, and the antibacterial agent is a nano titanium dioxide silver-loaded antibacterial agent.

Alternatively to this, the first and second parts may,

the adhesive is polyvinyl acetate, and the dispersing agent is polyvinyl alcohol.

A preparation method of a medical cosmetic antibacterial denture base material comprises the following steps:

a: preparing a base material, namely firstly putting polymethyl methacrylate into a crusher for crushing, then crushing the crushed polymethyl methacrylate into powder by a ball mill, after sieving, putting the polymethyl methacrylate powder into a stirrer with a heating and heat-insulating function, simultaneously adding acrylic resin, stirring for 12-15 min at the speed of 150-180 r/min, and uniformly mixing the acrylic resin and the polymethyl methacrylate to prepare the denture base material;

b: mixing reinforcing materials, namely putting a first reinforcing agent and a second reinforcing agent into a denture base material, heating to 67-85 ℃, stirring at the speed of 170-200 r/min for 10-14 min, and mixing the first reinforcing agent and the second reinforcing agent with the denture base material to prepare a reinforcing mixture;

c: adding a bacteriostatic agent and an antibacterial agent into a ball mill, blending the bacteriostatic agent and the antibacterial agent by the ball mill to prepare a bacteriostatic and antibacterial mixed material, adding the bacteriostatic and antibacterial mixed material into a reinforced mixed material, heating the mixed material to 30-50 ℃, mixing the reinforced mixed material and the bacteriostatic and antibacterial mixed material by a stirrer at the rotating speed of 170-200 r/min for 3-5 min to prepare a bacteriostatic and antibacterial reinforced mixed material;

d: uniformly mixing and melting, pouring deionized water into the antibacterial and antibacterial reinforced mixture, keeping the heating temperature at 20-30 ℃, then putting a dispersing agent into the antibacterial and antibacterial reinforced mixture, uniformly stirring at the speed of 180-220 r/min for 4-6 min, then adding an adhesive, uniformly stirring at the speed of 180-220 r/min for 7-10 min, and standing the antibacterial and antibacterial reinforced mixture for 2-4 h to enable the antibacterial and antibacterial reinforced mixture to naturally precipitate;

e: preparing a base, namely putting a naturally precipitated antibacterial and antibacterial reinforced mixture into a base reactor, uniformly suspending materials in the antibacterial and antibacterial reinforced mixture through ultrasonic dispersion, then putting the suspended materials into a base mold, heating the base mold to 75-85 ℃, heating for 12-24 min to gradually agglomerate the suspended materials, then heating to 90-98 ℃, and heating at constant temperature for 45-70 min to prepare a curing base;

f: and (3) demolding, namely separating the cured base support from the mold, standing to reduce the temperature to normal temperature, then sequentially performing coarse grinding and fine grinding on the surface of the base support to smooth the surface of the base support, then soaking the base support in distilled water at 65-80 ℃ for 10-30 s, and then drying the surface of the base support through a high-pressure air gun.

Optionally, in the step a, the crushed polymethyl methacrylate is sieved by a sieve with 70-90 meshes.

Optionally, in the step D, after the mixture is left to stand, 2 to 4 parts of preservative (by mass percentage) are added, and the mixture is uniformly stirred at a speed of 180 to 200r/min for 3 to 5 min.

(III) advantageous effects

The invention provides a medical beauty antibacterial denture base material and a preparation method thereof, and the material has the following beneficial effects:

(1) the invention uses polymethyl methacrylate and acrylic resin as basic materials, so that the production cost of the denture base is greatly reduced, the economic burden of a user is reduced, meanwhile, the bacteriostatic agent chitosan fiber and the antibacterial agent nano titanium dioxide silver-carrying antibacterial agent are used for keeping the hardness of the denture base, keeping the wearing comfort and having stronger stability, and inhibiting the bacteria proliferation in the oral cavity, inhibiting the adhesion of bacteria on the surface of the denture base and further improving the antibacterial and bacteriostatic effects of the denture base, the nano titanium dioxide silver-carrying antibacterial agent has stable heat resistance and good chemical stability, can kill bacteria and viruses, can eliminate the residues of the bacteria and the viruses by complete decomposition, has wide antibacterial range and lasting antibacterial effect, thereby improving the cleanliness of the oral cavity of the denture user, and avoiding the oral cavity infection of the user caused by bacteria, the use is healthier.

(2) The invention enhances the stability and hardness of the base through the first enhancer chromium oxide, improves the supporting strength of the denture during shearing through the second enhancer lead-free boron carbide ceramic, and enhances the connection stability between the denture and the base, thereby ensuring the mechanical strength of the denture in use and the use comfort of a user.

(3) The invention has simple process, low equipment requirement and stronger operability, and greatly reduces the production cost of the denture base, thereby having good social popularization benefit.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.