阅读说明：本技术 一种基于储存温度和储存时间预测乳粉中羟甲基糠醛和糠醛含量的方法 (Method for predicting content of hydroxymethylfurfural and furfural in milk powder based on storage temperature and storage time ) 是由 邢倩倩 游春苹 刘振民 扶晓菲 于 2020-07-01 设计创作，主要内容包括：本发明涉及食品领域,特别是涉及一种基于储存温度和储存时间预测乳粉中羟甲基糠醛和糠醛含量的方法。本发明提供一种基于储存温度和储存时间预测乳粉中羟甲基糠醛和糠醛含量的方法,包括：(1)提供乳粉样品中羟甲基糠醛的初始含量和/或糠醛的初始含量；(2)根据式(a)计算获得储存后样品中羟甲基糠醛的含量；(3)根据式(b)计算获得储存后样品中糠醛的含量。本发明所提供的基于储存温度和储存时间预测乳粉中羟甲基糠醛和糠醛含量的方法,具有适用温度广、适用时间长等特点,且可以准确预测特定时间和温度范围内的乳粉中羟甲基糠醛和糠醛含量的含量。(The invention relates to the field of food, in particular to a method for predicting the content of hydroxymethyl furfural and furfural in milk powder based on storage temperature and storage time. The invention provides a method for predicting the content of hydroxymethylfurfural and furfural in milk powder based on storage temperature and storage time, which comprises the following steps: (1) providing an initial content of hydroxymethylfurfural and/or an initial content of furfural in a milk powder sample; (2) calculating and obtaining the content of the hydroxymethylfurfural in the stored sample according to the formula (a); (3) and (c) calculating according to the formula (b) to obtain the content of the furfural in the stored sample. The method for predicting the contents of the hydroxymethylfurfural and the furfural in the milk powder based on the storage temperature and the storage time has the characteristics of wide application temperature, long application time and the like, and can accurately predict the contents of the hydroxymethylfurfural and the furfural in the milk powder within a specific time and temperature range.)

1. A method for predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time, comprising:

(1) providing an initial content of hydroxymethylfurfural and/or an initial content of furfural in a milk powder sample;

(2) calculating and obtaining the content of the hydroxymethylfurfural in the stored sample according to the formula (a);

(3) calculating according to the formula (b) to obtain the content of furfural in the stored sample;

C_f＝e^(a1-b1/T)t+C₀(a)

C_f’＝e^(a2-b2/T)t+C₀’ (b)

wherein, C_fAnd C₀Respectively representing the content of the hydroxymethylfurfural in the stored sample and the initial content of the hydroxymethylfurfural in the sample;

C_f' and C₀' the content of furfural in the sample after storage and the initial content of furfural in the sample are respectively;

t is the storage temperature;

t is the storage time;

a1＝30.555±10，b1＝8717.4±2000；

a2＝33.895±5，b2＝10500±1000。

2. the method for predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time of claim 1, wherein a1 is 30.555 ± 1, b1 is 8717.4 ± 100, a2 is 33.895 ± 1, and b2 is 10500 ± 100.

3. The method for predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time of claim 1, wherein in the formula (a), C_fHas the unit of mu g/100g, C₀In units of μ g/100g, T in units of K, and T in units of days.

4. The method for predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time of claim 1, wherein in the formula (b), C_fThe unit of' is μ g/100g, C₀The unit of' is mug/100g, T in units of K and T in units of days.

5. The method for predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time as claimed in claim 1, wherein the storage temperature is 20-70 ℃.

6. The method for predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time of claim 1 wherein the storage time is 720 days or less.

7. The method for predicting hydroxymethylfurfural and furfural content of milk powder based on storage temperature and storage time of claim 1 wherein the milk powder is selected from the group consisting of whole milk powder.

8. A computer-readable storage medium, on which a computer program is stored, which when executed by a processor implements the method of predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time according to any one of claims 1 to 7.

9. An apparatus, comprising: a processor and a memory, the memory storing a computer program, the processor executing the computer program stored by the memory to cause the apparatus to perform the method of predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time of any one of claims 1 to 7.

10. An apparatus, the apparatus comprising:

an initial content providing module, which is used for providing an initial content of hydroxymethyl furfural and/or an initial content of furfural in the milk powder sample;

the hydroxymethylfurfural content calculation module is used for calculating and obtaining the content of the hydroxymethylfurfural in the stored sample according to the formula (a); the furfural content calculation module is used for calculating and obtaining the content of furfural in the stored sample according to the formula (b);

C_f＝e^(a1-b1/T)t+C₀(a)

C_f’＝e^(a2-b2/T)t+C₀’ (b)

wherein, C_fAnd C₀Respectively representing the content of the hydroxymethylfurfural in the stored sample and the initial content of the hydroxymethylfurfural in the sample;

C_f' and C₀' the content of furfural in the sample after storage and the initial content of furfural in the sample are respectively;

t is the storage temperature;

t is the storage time;

a1＝30.555±10，b1＝8717.4±2000；

a2＝33.895±5，b2＝10500±1000。

Technical Field

The invention relates to the field of food, in particular to a method for predicting the content of hydroxymethyl furfural and furfural in milk powder based on storage temperature and storage time.

Background

The milk powder is the best cow's milk substitute recognized by people, wherein the infant formula milk powder is the main part of the milk powder market, and the problem of solving the quality safety problem of the milk powder is also a problem which is greatly concerned by the society. As one of the normal-temperature dairy products, the recommended storage mode of the milk powder is to store the milk powder at room temperature in a dark place, so that certain high-temperature and high-humidity conditions cannot be avoided in the storage process. During the storage of the milk powder, the physical and chemical reactions such as the denaturation and aggregation of whey protein, the isomerization and degradation of lactose, the maillard reaction and the like occur with the passage of time. The Maillard reaction can produce furfuryl acid, furfural compounds, glycosylation end products and the like. If a large amount of the substance is ingested, the heart, the liver and the kidney and other organs can be damaged, such as diabetes, renal failure, Alzheimer's disease and the like, inflammation is induced, oxidative stress is enhanced, and atherosclerosis is promoted. Therefore, if a method can quickly predict the content of the furfural compounds in the milk powder under different storage conditions, the method can greatly help to control the quality and the shelf life of the milk powder.

Disclosure of Invention

In view of the above-mentioned drawbacks of the prior art, an object of the present invention is to provide a method for predicting the content of hydroxymethylfurfural and furfural in milk powder based on storage temperature and storage time, which solves the problems in the prior art.

To achieve the above and other related objects, the present invention provides, in one aspect, a method for predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time, comprising:

(1) providing an initial content of hydroxymethylfurfural and/or an initial content of furfural in a milk powder sample;

(2) calculating and obtaining the content of the hydroxymethylfurfural in the stored sample according to the formula (a);

(3) calculating according to the formula (b) to obtain the content of furfural in the stored sample;

C_f＝e^(a1-b1/T)t+C₀(a)

C_f’＝e^(a2-b2/T)t+C₀’ (b)

wherein, C_fAnd C₀Respectively representing the content of the hydroxymethylfurfural in the stored sample and the initial content of the hydroxymethylfurfural in the sample;

C_f' and C₀' the content of furfural in the sample after storage and the initial content of furfural in the sample are respectively;

t is the storage temperature;

t is the storage time;

a1＝30.555±10，b1＝8717.4±2000；

a2＝33.895±5，b2＝10500±1000。

in some embodiments of the present invention, a1 ═ 30.555 ± 1, b1 ═ 8717.4 ± 100, a2 ═ 33.895 ± 1, and b2 ═ 10500 ± 100.

In some embodiments of the invention, in formula (a), C_fHas the unit of mu g/100g, C₀In units of μ g/100g, T in units of K, and T in units of days.

In some embodiments of the invention, in formula (b), C_fThe unit of' is μ g/100g, C₀Unit of' is μ g/100g, unit of T is K, unit of T is day.

In some embodiments of the present invention, the storage temperature is 20 to 70 ℃.

In some embodiments of the invention, the storage time is 720 days or less.

In some embodiments of the invention, the milk powder is selected from whole milk powder.

Another aspect of the present invention provides a computer-readable storage medium, on which a computer program is stored, which when executed by a processor, implements the above-described method for predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time.

In another aspect, the invention provides an apparatus comprising: a processor and a memory, the memory being configured to store a computer program, the processor being configured to execute the computer program stored by the memory to cause the apparatus to perform the above-described method of predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time.

Another aspect of the present invention provides an apparatus, which may include:

an initial content providing module, which is used for providing an initial content of hydroxymethyl furfural and/or an initial content of furfural in the milk powder sample;

the hydroxymethylfurfural content calculation module is used for calculating and obtaining the content of the hydroxymethylfurfural in the stored sample according to the formula (a);

the furfural content calculation module is used for calculating and obtaining the content of furfural in the stored sample according to the formula (b);

C_f＝e^(a1-b1/T)t+C₀(a)

C_f’＝e^(a2-b2/T)t+C₀’ (b)

wherein, C_fAnd C₀Respectively representing the content of the hydroxymethylfurfural in the stored sample and the initial content of the hydroxymethylfurfural in the sample;

C_f' and C₀' the content of furfural in the sample after storage and the initial content of furfural in the sample are respectively;

t is the storage temperature;

t is the storage time;

a1＝30.555±10，b1＝8717.4±2000；

a2＝33.895±5，b2＝10500±1000。

drawings

Fig. 1 is a schematic diagram showing a model verification result of HMF in hydroxymethylfurfural in example 2 of the present invention.

Fig. 2 is a schematic diagram showing a model verification result of furfural F in example 2 of the present invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments, and other advantages and effects of the present invention will be apparent to those skilled in the art from the disclosure of the present specification.

Through a large amount of researches, the inventor establishes a mathematical model of the content change of furfural compounds (hydroxymethyl furfural CAS NO.67-47-0 and furfural CAS NO.98-01-1) in the storage temperature, the storage time and the storage process aiming at the milk powder, and can accurately predict the content change of the furfural compounds in the milk powder in the storage process at various temperatures based on the mathematical model, thereby completing the invention.

The invention provides a method for predicting the content of hydroxymethyl furfural and furfural in milk powder based on storage temperature and storage time, which comprises the following steps:

(1) providing an initial content of hydroxymethylfurfural and/or an initial content of furfural in a milk powder sample;

(2) calculating and obtaining the content of the hydroxymethylfurfural in the stored sample according to the formula (a);

(3) calculating according to the formula (b) to obtain the content of furfural in the stored sample;

C_f＝e^(a1-b1/T)t+C₀(a)

C_f’＝e^(a2-b2/T)t+C₀’ (b)

wherein, C_fAnd C₀The content of the hydroxymethylfurfural in the sample after storage and the initial content of the hydroxymethylfurfural in the sample, C_fMay have a unit of μ g/100g, C₀The unit of (d) may be μ g/100 g;

C_f' and C₀' Furfural content in the sample after storage and initial Furfural content in the sample, C_fThe unit of' may be μ g/100g, C₀The unit of' may be μ g/100 g;

t is the storage temperature, and the unit of T can be K;

t is the storage time, and the unit of t can be days;

a1 can be 30.555 + -10, 30.555 + -5, 30.555 + -3, 30.555 + -1, 30.555 + -0.8, 30.555 + -0.6, 30.555 + -0.4, 30.555 + -0.2 or 30.555 + -0.1;

the value of b1 can be 8717.4 + -2000, 8717.4 + -1500, 8717.4 + -1000, 8717.4 + -800, 8717.4 + -600, 8717.4 + -400, 8717.4 + -200, 8717.4 + -100, 8717.4 + -80, 8717.4 + -60, 8717.4 + -40, 8717.4 + -20, or 8717.4 + -10;

the value of a2 can be 33.895 + -5, 33.895 + -3, 33.895 + -1, 33.895 + -0.8, 33.895 + -0.6, 33.895 + -0.4, 33.895 + -0.2 and 33.895 + -0.1;

the value of b2 can be 10500 + -1000, 10500 + -800, 10500 + -600, 10500 + -400, 10500 + -200, 10500 + -100, 10500 + -80, 10500 + -60, 10500 + -40, 10500 + -20, or 10500 + -10.

As described above, the content of the furfural substances in the milk powder after being stored for a certain time can be obtained according to the equation of the formula a and the equation of the formula b. The content of the hydroxymethyl furfural and the change of the content of the furfural in the storage process of the milk powder have close relation with the storage temperature and the storage time of the milk powder, and other conditions (such as humidity and the like) have no obvious influence on the content change of furfural substances. Generally, the longer the storage time and/or the higher the storage temperature of the milk powder, the higher the content of hydroxymethylfurfural and/or the content of furfural. However, this variation relationship is not a simple linear relationship. Through a pre-established relation equation, the content change of the furfural compounds in the milk powder in the storage process at each temperature can be more accurately reflected by a zero-order reaction model established through the storage temperature and the storage time.

In the method for predicting the content of hydroxymethylfurfural and furfural in milk powder based on the storage temperature and the storage time, the milk powder is usually prepared into the obtained powdered dairy product by removing almost all water in milk through a proper treatment process and drying. These treatment processes may generally include raw material pretreatment, concentration, sterilization, drying, and the like. The kind of the milk powder can be full-fat milk powder and the like, and the full-fat milk powder can be prepared or not, and can be the full-fat milk powder which is generally in accordance with the definition of the relevant standard of GB 19644-2010.

In the method for predicting the content of hydroxymethylfurfural and furfural in milk powder based on the storage temperature and the storage time, the value range of the storage temperature in the equation a and the equation b can be specifically 20-70 ℃, 20-30 ℃, 30-40 ℃, 40-50 ℃, 50-60 ℃ or 60-70 ℃. The common storage temperature of the milk powder can be 25-40 ℃, so the method provided by the application can be suitable for various common storage temperature conditions of the milk powder.

In the method for predicting the content of hydroxymethylfurfural and furfural in milk powder based on the storage temperature and the storage time, the value of the storage time in the equation a and the equation b can be less than or equal to 720 days, less than or equal to 30 days, 30-60 days, 60-90 days, 90-180 days, 180-360 days, 360-540 days or 540-720 days. The shelf life of the milk powder is usually not more than 360-540 days, so the method provided by the application can cover the shelf life of the milk powder in a wider range.

A second aspect of the present invention provides a computer-readable storage medium having stored thereon a computer program which, when executed by a processor, implements the method for predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time provided by the first aspect of the present invention.

A third aspect of the invention provides an apparatus comprising: a processor and a memory, the memory being configured to store a computer program, the processor being configured to execute the computer program stored by the memory to cause the apparatus to perform the method for predicting hydroxymethylfurfural and furfural content in milk powder based on storage temperature and storage time as provided by the first aspect of the present invention.

A fourth aspect of the present invention provides an apparatus, which may comprise:

an initial content providing module, which is used for providing an initial content of hydroxymethyl furfural and/or an initial content of furfural in the milk powder sample;

the hydroxymethylfurfural content calculation module is used for calculating and obtaining the content of the hydroxymethylfurfural in the stored sample according to the formula (a);

the furfural content calculation module is used for calculating and obtaining the content of furfural in the stored sample according to the formula (b);

C_f＝e^(a1-b1/T)t+C₀(a)

C_f’＝e^(a2-b2/T)t+C₀’ (b)

wherein, C_fAnd C₀Respectively representing the content of the hydroxymethylfurfural in the stored sample and the initial content of the hydroxymethylfurfural in the sample;

C_f' and C₀' Furfural content in the stored samplesAnd the initial content of furfural in the sample;

t is the storage temperature;

t is the storage time;

a1＝30.555±10，b1＝8717.4±2000；

a2＝33.895±5，b2＝10500±1000。

in the present invention, the operation principle of each module in the above apparatus may refer to the method for predicting the content of hydroxymethylfurfural and furfural in milk powder based on the storage temperature and the storage time provided by the first aspect of the present invention, which is not described herein again.

The method for predicting the content of the hydroxymethylfurfural and furfural in the milk powder based on the storage temperature and the storage time has the characteristics of wide application temperature, long application time and the like, can accurately predict the content of the hydroxymethylfurfural and furfural in the milk powder within a specific time and temperature range, can provide favorable basis for the prediction and evaluation of the shelf life of the milk powder, the limit standard of furfural compounds and the like, and has good industrial prospect.

The invention of the present application is further illustrated by the following examples, which are not intended to limit the scope of the present application.