阅读说明：本技术 基于吡啶酮的表观遗传修饰剂及其用途 (Pyridone-based epigenetic modifiers and uses thereof ) 是由 G·R·撒切尔 熊瑞 赵颎 李洋峰 于 2018-12-01 设计创作，主要内容包括：本文描述了基于吡啶酮的化合物、其衍生物以及其药物制剂。在一些方面中,基于吡啶酮的化合物、其衍生物和/或其药物制剂可以被施用至有相应需要的受试者。在一些方面中,基于吡啶酮的化合物、其衍生物和/或其药物制剂可以调节BRD蛋白和/或BET蛋白的活性和/或功能。(Described herein are pyridone-based compounds, derivatives thereof, and pharmaceutical formulations thereof. In some aspects, the pyridone-based compounds, derivatives thereof, and/or pharmaceutical formulations thereof can be administered to a subject in need thereof. In some aspects, the pyridone-based compounds, derivatives thereof, and/or pharmaceutical formulations thereof may modulate the activity and/or function of a BRD protein and/or a BET protein.)