阅读说明：本技术 一种断面平整安瓿 (Ampoule with smooth section ) 是由 薛刚强 郝景书 潘新艳 高建军 薛梅 于 2020-07-29 设计创作，主要内容包括：本发明涉及一种断面平整安瓿,其包括自下而上设置的瓶底、瓶身、肩部、颈部、泡部和丝部,所述肩部曲线的形状为自下而上先凹后凸的渐变曲线,本发明所提供的断面平整安瓿能够符合国内和国标玻璃安瓿的使用要求,满足安瓿瓶折断力测试,有利于提高玻璃安瓿瓶颈部掰断后的断面平整度,提高玻璃安瓿颈部折断所需施加折断力的大小一致性,提高了安瓿瓶在用于水针剂生产中的利用率,保证了安瓿瓶在使用中的安全性,降低医疗事故发生,本发明同时适用于对颈部折断后有颈部断面平整度要求的其他易折类容器。(The invention relates to a flat section ampoule, which comprises a bottom, a body, a shoulder, a neck, a bubble part and a filament part, wherein the shoulder curve is a gradual change curve which is concave from bottom to top and then convex.)

1. The ampoule with a smooth section is characterized by comprising a bottom, a body, a shoulder, a neck, a soaking part and a filament part which are arranged from bottom to top, wherein the shape of the shoulder curve is a gradual curve which is concave from bottom to top firstly and then convex.

2. The ampoule of claim 1, wherein the distance H1 between the peak of the convex curve of the outer wall shoulder curve and the line segment between the two ends of the convex curve and the length L of the line segment between the two ends of the convex curve₁The ratio is 0.020-0.100, the ratio of the distance H2 from the lowest point of the concave curve of the outer wall shoulder curve to the line segment between the two ends of the concave curve to the length L2 of the line segment between the two ends of the concave curve is 0.040-0.130, and the ratio of the length of the line segment L1 between the two ends of the convex curve of the outer wall to the length of the line segment L2 between the two ends of the concave curve is 0.300-0.800.

3. The ampoule of claim 1, wherein the ratio of the distance H3 between the peak of the convex curve of the inner wall shoulder curve and the line segment between the two ends of the convex curve to the length L3 between the two ends of the convex curve is 0.010-0.075, the ratio of the distance H4 between the lowest point of the concave curve of the inner wall shoulder curve and the line segment between the two ends of the concave curve to the length L4 between the two ends of the concave curve is 0.030-0.105, and the ratio of the length of the line segment L3 between the two ends of the inner wall convex curve and the line segment L4 between the two ends of the concave curve is 0.500-1.000.

4. The flat ampoule of claim 1, wherein the neck curve has a best fit radius R of 0.3mm to 3.0 mm.

5. The ampoule of claim 1, wherein the ratio of the distance D1 between the neck of the outer wall and the lower end face of the shoulder to the difference D2 between the radii of the neck of the outer wall and the lower end face of the shoulder is 1.105-1.303.

6. The ampoule of claim 1, wherein the ratio of the distance D3 between the neck of the inner wall and the lower end surface of the shoulder to the difference D4 between the radius of the neck of the inner wall and the lower section of the shoulder is 1.095-1.262.

7. The ampoule of claim 1, wherein the length P1P2 of the line from the neck of the outer wall to the lower end of the shoulder curve is 0.991-13.487 mm.

8. The ampoule of claim 1, wherein the length P3P4 of the line from the neck of the inner wall to the lower end of the shoulder curve is 1.062-14.456 mm.

9. The ampoule of claim 1, wherein the ratio of the length L1 of the line segment between the two ends of the convex curve of the outer wall to the length P1P2 of the line segment from the neck of the outer wall to the lower end of the curve of the shoulder is 0.232-0.470.

10. The ampoule of claim 1, wherein the ratio of the length L3 of the line segment between the two ends of the convex curve of the inner wall to the length P3P4 of the line connecting the neck of the inner wall to the lower end of the curve of the shoulder is 0.334-0.530.

Technical Field

The invention belongs to the technical field of materials and containers for medicine packaging, and particularly relates to an ampoule with a flat section.

Background

The ampoule bottle is a sealed small bottle made of high-quality thin glass, is commonly used for storing medicines for injection, vaccines, serum and the like, and has the capacity of 1-25 ml generally. According to the YBB national medicinal packaging container material standard and related international relevant standards, the prior glass ampoule is divided into a point-nicked curved neck easy-to-break glass ampoule and a color ring curved neck easy-to-break glass ampoule, the color ring curved neck easy-to-break glass ampoule is formed by adding a glass colored glaze ring with a linear thermal expansion coefficient larger than that of ampoule glass at the position of the ampoule curved neck, and after an annealing process, the colored glaze ring is melted at the ampoule neck. The method has the advantages of complex process, increased cost, influence of the outer diameter and the thickness of the neck of the ampoule, and unsatisfactory effect when applied to the ampoule with the specification of 5mL or above. Nick point is broken off with fingers and thumb to the crooked neck glass ampoule of point score, and the bottleneck makes the neck fracture for the impetus, and the easy broken glass ampoule of the crooked neck of point score compares in color ring ampoule range of application extensively, but because traditional bent neck is easy broken glass ampoule neck shape design unreasonable, causes the easy broken glass ampoule of crooked neck and the difficult back ampoule neck section unevenness of rupture, still has the risk of hindering hand and piece entering liquid.

The inventor of the application filed for the patent of the bent-neck easy-to-break glass ampoule in 2015, and by adjusting parameters such as the shape of the shoulder, the shape of the shoulder and the shape of a connecting arc between the shoulder and the bulb, the flatness of the section is obviously improved, and the use safety is improved. At present, except that the section flatness of the broken neck of the glass ampoule is used as an evaluation index of ampoule quality, the breaking force applied by breaking the neck of the glass ampoule is an important performance parameter for evaluating the quality of the ampoule, and the invention provides a group for deeply and comprehensively researching the structure of the ampoule based on the research foundation in order to further improve the section flatness and the breaking force conformity of the broken neck of the ampoule.

Disclosure of Invention

The invention aims to overcome the defects in the prior art and provide a flat glass ampoule with a flatter neck section and more excellent breaking force performance.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows:

the ampoule with a smooth section comprises a bottom, a body, a shoulder, a neck, a bubble part and a filament part which are arranged from bottom to top, wherein the shape of the shoulder curve is a gradual change curve which is concave from bottom to top firstly and then convex.

As some preferred embodiments of the present invention, the ratio of the distance H1 from the highest point of the convex curve of the outer wall shoulder curve to the line segment between the two ends of the convex curve to the length L1 of the line segment between the two ends of the convex curve is 0.020 to 0.100, the ratio of the distance H2 from the lowest point of the concave curve of the outer wall shoulder curve to the line segment between the two ends of the concave curve to the length L2 of the line segment between the two ends of the concave curve is 0.040 to 0.130, and the ratio of the length of the line segment L1 between the two ends of the outer wall convex curve to the length of the line segment L2 between the two ends of the.

As some preferred embodiments of the present invention, the ratio of the distance H3 from the highest point of the convex curve of the inner wall shoulder curve to the line segment between the two ends of the convex curve to the length L3 of the line segment between the two ends of the convex curve is 0.010 to 0.075, the ratio of the distance H4 from the lowest point of the concave curve of the inner wall shoulder curve to the line segment between the two ends of the concave curve to the length L4 of the line segment between the two ends of the concave curve to the length L4 of the line segment between the two ends of the concave curve is 0.030 to 0.105, and the ratio of the length L3 of the line segment between the two ends of the inner wall.

As some preferred embodiments of the present invention, the neck curve has a best-fit radius R of 0.3mm to 3.0 mm.

As some preferred embodiments of the invention, the ratio of the distance D1 from the neck part of the outer wall to the lower end face of the shoulder part to the radius difference D2 between the neck part of the outer wall and the lower end face of the shoulder part is 1.105-1.303.

As some preferred embodiments of the invention, the ratio of the distance D3 from the neck part of the inner wall to the lower end face of the shoulder part to the radius difference D4 of the lower section of the neck part of the inner wall and the lower section of the shoulder part is 1.095-1.262.

As some preferred embodiments of the present invention, the length P1P2 of the line connecting the neck of the outer wall to the lower end of the shoulder curve is 0.991 to 13.487 mm.

As some preferred embodiments of the present invention, the length P3P4 of the connecting line from the neck part of the inner wall to the lower end part of the shoulder curve is 1.062-14.456 mm.

As some preferred embodiments of the present invention, the ratio of the length L1 of the line segment between the two ends of the convex curve of the outer wall to the length P1P2 of the line connecting the neck of the outer wall to the lower end of the curve of the shoulder is 0.232-0.470.

As some preferred embodiments of the present invention, the ratio of the length L3 of the line segment between the two ends of the curve of the convex portion of the inner wall to the length P3P4 of the line connecting the neck portion of the inner wall to the lower end portion of the curve of the shoulder portion is 0.334-0.530.

The ampoule bottle be provided with the nick on the neck, the length of nick, body external diameter, body full height, end to neck height, end to shoulder height, silk external diameter, bubble external diameter, neck external diameter etc. main appearance size all are in national standard range.

Explanation of technical terms

The lengths of the invention are measured by a three-dimensional scanner with the precision of +/-0.005 mm, so that the lengths of the parameters have errors of +/-0.005 mm, and the invention is suitable for the lengths of the invention within the error range.

Shoulder curves of the invention: is a section of a curve formed by the outer wall of the ampoule in an axial section passing through the axis of the ampoule bottle. The starting point of the shoulder curve of the outer wall is the connecting point of the shoulder and the neck, namely a point P1 in figure 2, the terminal point is the terminal point of the transition smooth curve extending downwards, when the shoulder and the bottle body are squeezed to form a folding, the terminal point is the squeezing folding position of the shoulder and the bottle body, when the shoulder and the bottle body are not squeezed, the terminal point is the connecting point of the shoulder and the bottle body transition curve, namely a point P2 in figure 2. The starting point of the shoulder curve of the inner wall is the connecting point of the shoulder and the neck, namely a point P3 in fig. 2, the terminal point is the terminal point of the transition smooth curve extending downwards, when the shoulder and the bottle body are squeezed to form a fold, the terminal point is the squeezing fold of the shoulder and the bottle body, when the shoulder and the bottle body are not squeezed to form a fold, the terminal point is the connecting point of the shoulder and the transition curve of the bottle body, namely a point P4 in fig. 2, and the starting point is shown in fig. 2.

The shoulder curve is a gradual curve which is concave first and convex second from bottom to top, and means that a curve formed by the outer wall of the shoulder of the ampoule bottle in an axial section passing through the axle center of the ampoule bottle is a curve which is concave first and convex second from bottom to top, a point M1 is an intersection point of a concave curve and a convex curve and is an automatic point taking point during measurement of a three-dimensional scanner, the curve P2M1 is positioned on one side of a straight line P2M1 close to the bottle body, and the curve M1P1 is positioned on one side of the straight line P1M1 far away from the bottle body. The curve formed by the inner wall of the ampoule shoulder is a curve which is concave from bottom to top and then convex, the point M2 is the intersection point of the concave curve and the convex curve, the curve P4M2 is positioned on the side of the straight line P4M2 close to the bottle body, and the curve M2P3 is positioned on the side of the straight line M2P3 far away from the bottle body, which is shown in figure 2.

The best-fit radius R of the neck curve is the fit radius of the neck curve, and refers to the best-fit radius of a transition curve formed by the upward extension or the downward extension of the narrowest part of the neck, P1P5 is the arc length of the neck curve, and P5 is the intersection point of the neck curve and the bulb curve in a smooth transition mode, and is shown in figure 2.

L1 is the length of the segment P1M1 between two ends of the convex part curve of the outer wall shoulder curve. H1 is the distance from the highest point of the convex curve of the outer wall shoulder curve to the segment P1M1 between the two ends of the convex curve, L2 is the length of the segment P2M1 between the two ends of the concave curve of the outer wall shoulder curve, and H2 is the distance from the lowest point of the concave curve of the outer wall shoulder curve to the segment P2M1 between the two ends of the concave curve, as shown in FIG. 2.

L3 is the length of the line segment P3M2 between the two ends of the convex part curve of the inner wall shoulder curve, H3 is the distance from the highest point of the convex part curve of the inner wall shoulder curve to the line segment P3M2 between the two ends of the convex part curve, L4 is the length of the line segment P4M2 between the two ends of the concave part curve of the inner wall shoulder curve, and H4 is the distance from the lowest point of the concave part curve of the inner wall shoulder curve to the line segment P4M2 between the two ends of the concave part curve, as shown in figure 2.

D1 is the distance from the neck of the outer wall to the lower end face of the shoulder, namely the distance from P1 to the projection point of the lower end face of the shoulder. D2 is the difference in radius between the lower end faces of the neck and shoulder portions of the outer wall. As shown in fig. 2.

D3 is the distance from the neck of the inner wall to the lower end surface of the shoulder, namely the distance from P3 to the projection point of the lower end surface of the shoulder. D4 is the difference in radius of the lower end face of the neck and shoulder portions of the inner wall. As shown in fig. 2.

The breaking force of the ampoule bottle is an important performance parameter for judging the quality of the ampoule bottle, the breaking force required to be applied for breaking the neck of the glass ampoule bottle is required to be more consistent on the premise of meeting the national standard requirement, and the yield and the safety of the glass ampoule bottle in the production and transportation process of the injection are ensured. Previous studies by the present team have shown that the shoulder is shaped in a concave curve into the body, which is more likely to form a force-prone ring at the neck of the ampoule than a drum shoulder. However, in later studies, it was found that there is still room for improvement, although the flatness of the cross section can be improved to some extent. Attempts have been made to adjust the thickness of the concave curve in order to improve the breaking force performance, and neither of these effects has been satisfactory by thickening or thinning. On the basis, the shape of the shoulder curve is investigated, and the fact that the upper part of the concave curve is convexly designed is found to have certain contribution to the fracture force performance, so that the neck curve fitting radius R is further optimized, and the neck curve fitting radius R also has certain contribution to the fracture force uniformity and the section flatness. Therefore, the ratio of the concave curve to the convex curve and the contribution of the curve shape to the breaking force performance and the existence of the breaking force performance are searched, and the technical scheme of the invention is obtained.

Adopt the produced beneficial effect of above-mentioned technical scheme to lie in:

the ampoule with a flat section provided by the invention can meet the breaking force test of the ampoule bottle and meet the use requirements of national and non-national standard glass ampoules. The method is favorable for improving the section flatness of the broken glass ampoule bottle neck, improving the consistency of the breaking force required by the breaking of the glass ampoule bottle neck, effectively reducing the breakage rate of the ampoule bottle in the operation of filling and sealing liquid medicine and the transportation of the filled and sealed water injection, improving the safety of the water injection and reducing the occurrence of medical accidents.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic diagram of the shoulder curve of the present invention;

in the drawings:

1 bottle bottom, 2 bottle bodies, 3 bottle body shoulders, 4 neck parts, 5 bubble parts and 6 silk parts.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in detail and fully with reference to the following embodiments.

As shown in fig. 1 and 2, an ampoule with a flat section comprises a bottom 1, a body 2, a shoulder 3, a neck 4, a bubble portion 5 and a filament portion 6, which are arranged in sequence from bottom to top, wherein the neck 4 is the thinnest part of the outer diameter of the ampoule and is also the part with the largest curvature between the shoulder 3 and the bubble portion 5 in a curve formed by the outer wall of the ampoule in the axial section, the neck 4 is provided with nicks, the nicks are 1 mm-4 mm long, the shoulder curve is a gradually-changing curve which is concave from bottom to top and then convex, and other dimensions are according to the packaging material and container standard of direct contact medicines issued by the national food and drug administration, but are not limited to the above standard.

The ratio of the distance H1 from the highest point of the convex part curve of the outer wall shoulder curve to the line segment between the two ends of the convex part curve to the length L1 of the line segment between the two ends of the convex part curve is 0.020-0.100, the ratio of the distance H2 from the lowest point of the concave part curve of the outer wall shoulder curve to the line segment between the two ends of the concave part curve to the length L2 of the line segment between the two ends of the concave part curve is 0.040-0.130, and the ratio of the length L2 of the line segment between the line segment L1 between the two ends of the convex part curve of the outer wall and the two.

The ratio of the distance H3 from the highest point of the convex part curve of the inner wall shoulder curve to the line segment between the two ends of the convex part curve to the length L3 of the line segment between the two ends of the convex part curve is 0.010-0.075, the ratio of the distance H4 from the lowest point of the concave part curve of the inner wall shoulder curve to the line segment between the two ends of the concave part curve to the length L4 of the line segment between the two ends of the concave part curve is 0.030-0.105, and the ratio of the length L4 of the line segment between the line segment L3 between the two ends of the convex part curve and the two ends.

The best fitting radius of the neck curve is that R is 0.3 mm-3.0 mm.

The ratio of the distance D1 from the neck part of the outer wall to the lower end face of the shoulder part to the radius difference D2 between the neck part of the outer wall and the lower end face of the shoulder part is 1.105-1.303.

The ratio of the distance D3 from the neck part of the inner wall to the lower end face of the shoulder part to the radius difference D4 between the neck part of the inner wall and the lower end face of the shoulder part is 1.095-1.262.

The length P1P2 of the line from the neck of the outer wall to the lower end of the shoulder curve is 0.991-13.487 mm.

The length P3P4 of the connecting line from the neck part of the inner wall to the lower end part of the shoulder curve is 1.062-14.456 mm.

The ratio of the length L1 of the line segment between the two ends of the convex curve of the outer wall to the length P1P2 of the connecting line from the neck of the outer wall to the lower end of the curve of the shoulder is 0.232-0.470.

The ratio of the length L3 of the line segment between the two ends of the convex curve of the inner wall to the length P3P4 of the connecting line of the neck part of the inner wall to the lower end part of the curve of the shoulder part is 0.334-0.530.