阅读说明：本技术 一种替代抗生素预防仔猪腹泻的饲料添加剂 (Feed additive for replacing antibiotics to prevent piglet diarrhea ) 是由 单玉平 蒋向君 刘文博 李锋 董燕萍 张雪君 周庆雨 史慧 顾宝勇 于 2020-05-08 设计创作，主要内容包括：本发明公开了一种替代抗生素预防仔猪腹泻的饲料添加剂,该替代抗生素预防仔猪腹泻的饲料添加剂按照重量份数计算,包括以下原料：甘草10-15份、马齿苋10-18份、复合蛋白粉10-20份、蒙脱石15-18份、双歧杆菌益生菌8-10份、复合维生素3-5份、陈皮2-3份、甜味剂1-3份；本发明所述的一种替代抗生素预防仔猪腹泻的饲料添加剂,通过使用中草药、益生菌以及蛋白质,使其具有替代抗生素的作用,其中复合蛋白粉能够增加仔猪免疫力,改善仔猪的胃肠道菌群,另外,复合益生菌、复合维生素以及蒙脱石相结合,具有修复受损肠粘膜,增强消化吸收功能,可有效地预防断奶仔猪腹泻。该添加剂制作成本低,操作工序简单。(The invention discloses a feed additive for replacing antibiotics to prevent piglet diarrhea, which comprises the following raw materials in parts by weight: 10-15 parts of liquorice, 10-18 parts of purslane, 10-20 parts of compound protein powder, 15-18 parts of montmorillonite, 8-10 parts of bifidobacterium probiotics, 3-5 parts of compound vitamin, 2-3 parts of dried orange peel and 1-3 parts of sweetener; the feed additive for preventing the diarrhea of the piglets by replacing the antibiotics has the function of replacing the antibiotics by using the Chinese herbal medicines, the probiotics and the protein, wherein the compound protein powder can increase the immunity of the piglets and improve the gastrointestinal flora of the piglets, and in addition, the compound probiotics, the compound vitamins and the montmorillonite are combined, so that the feed additive has the functions of repairing damaged intestinal mucosa, enhancing the digestion and absorption and can effectively prevent the diarrhea of the weaned piglets. The additive has low production cost and simple operation process.)

1. The feed additive for replacing antibiotics to prevent piglet diarrhea is characterized by comprising the following raw materials in parts by weight: 10-15 parts of liquorice, 10-18 parts of purslane, 10-20 parts of compound protein powder, 15-18 parts of montmorillonite, 8-10 parts of bifidobacterium probiotics, 3-5 parts of compound vitamin, 2-3 parts of dried orange peel and 1-3 parts of sweetener.

2. The feed additive for preventing piglet diarrhea instead of antibiotics according to claim 1, is characterized in that: the feed additive for replacing antibiotics to prevent piglet diarrhea comprises the following steps:

firstly, crushing soybeans, mixing the crushed soybeans with freeze-dried earthworm powder at a ratio of 5:1, adding water to prepare a 15-30 wt% mixed solution, uniformly stirring, adjusting the pH of the mixed solution to 5.0-7.5, adding alkaline protease, heating to 50-60 ℃, carrying out enzymolysis for 3-5h, filtering, concentrating the filtrate, and carrying out spray drying to obtain the compound protein powder;

step two, crushing treatment, namely crushing the dried orange peel, the liquorice and the purslane in sequence, mixing and sieving to obtain a mixture A, wherein a sieve is 25-40 meshes;

step three, merging and decocting, mixing the obtained mixture A with montmorillonite, uniformly stirring, adding water for decocting for 150min for 120-;

step four, mixing and drying, namely mixing the compound protein powder obtained in the step one with bifidobacteria probiotics and compound vitamin in sequence, uniformly stirring, and then putting into a vacuum freeze dryer at the temperature of-50 ℃ to-30 ℃ for 40-50min to obtain a mixture C for later use;

step five, extraction treatment, namely respectively putting the mixture B obtained in the step three and the sweetening agent into the mixture C obtained in the step four to heat and stir for 20-30min at 45-60 ℃, heating and extracting after uniformly stirring, then performing ultrasonic treatment, performing ultrasonic centrifugation and taking supernatant to finish the preparation of the feed additive for preventing piglet diarrhea by replacing antibiotics; finally obtaining the feed additive for preventing the piglet diarrhea.

3. The feed additive for preventing piglet diarrhea instead of antibiotics according to claim 1, is characterized in that: the compound vitamin is a mixture of vitamin B, vitamin C and vitamin E, and the ratio of the vitamin B to the vitamin C to the vitamin E is 2:2: 1.

4. The feed additive for preventing piglet diarrhea instead of antibiotics according to claim 2, is characterized in that: in the fifth step, the sweetener is 4 to 5 percent of neotame, and the carrier is anhydrous glucose.

5. The feed additive for preventing piglet diarrhea instead of antibiotics according to claim 2, is characterized in that: in the step five, the frequency of ultrasonic treatment is 25-40KHz, the ultrasonic power is 1050-1250w, and the treatment time is 30-45 min.

6. The feed additive for preventing piglet diarrhea instead of antibiotics according to claim 2, is characterized in that: the additive amount of the feed additive is 0.05-0.2% of the feed, and when the piglets are diarrhea, the additive amount of the feed additive is 0.2-0.35% of the feed.

Technical Field

The invention belongs to the technical field of feed additives, and particularly relates to a feed additive for replacing antibiotics to prevent piglet diarrhea.

Background

In the pig raising production, the diarrhea of piglets becomes one of the serious problems, which not only increases the medicine cost and causes the death of the piglets, but also causes the growth and development of the tolerant pigs to be influenced, and causes of diarrhea of the piglets are complex, and the diarrhea can be caused by single factors or multiple factors.

After the piglets have diarrhea, the breeders usually adopt the medicine containing the antibiotics to treat the piglets immediately, and use the antibiotics for a long time, so that the growth and development of the piglets are influenced to a certain extent, and meanwhile, the breeding cost is increased. Therefore, the feed additive for preventing the piglet diarrhea instead of the antibiotic is provided.

Disclosure of Invention

The invention mainly aims to provide a feed additive for preventing piglet diarrhea instead of antibiotics, which can effectively solve the problems in the background technology.

In order to achieve the purpose, the invention adopts the technical scheme that:

the feed additive for replacing antibiotics to prevent piglet diarrhea comprises the following raw materials in parts by weight: 10-15 parts of liquorice, 10-18 parts of purslane, 10-20 parts of compound protein powder, 15-18 parts of montmorillonite, 8-10 parts of bifidobacterium probiotics, 3-5 parts of compound vitamin, 2-3 parts of dried orange peel and 1-3 parts of sweetener.

Preferably, the feed additive for preventing piglet diarrhea instead of antibiotics comprises the following steps:

firstly, crushing soybeans, mixing the crushed soybeans with freeze-dried earthworm powder at a ratio of 5:1, adding water to prepare a 15-30 wt% mixed solution, uniformly stirring, adjusting the pH of the mixed solution to 5.0-7.5, adding alkaline protease, heating to 50-60 ℃, carrying out enzymolysis for 3-5h, filtering, concentrating the filtrate, and carrying out spray drying to obtain the compound protein powder;

step two, crushing treatment, namely crushing the dried orange peel, the liquorice and the purslane in sequence, mixing and sieving to obtain a mixture A, wherein a sieve is 25-40 meshes;

step three, merging and decocting, mixing the obtained mixture A with montmorillonite, uniformly stirring, adding water for decocting for 150min for 120-;

step four, mixing and drying, namely mixing the compound protein powder, the bifidobacterium probiotics and the compound vitamin obtained in the step one in sequence, uniformly stirring, and then putting into a vacuum freeze dryer at the temperature of between 50 ℃ below zero and 30 ℃ below zero for 40 to 50min to obtain a mixture C for later use;

step five, extraction treatment, namely respectively putting the mixture B obtained in the step three and the sweetening agent into the mixture C obtained in the step four to heat and stir for 20-30min at 45-60 ℃, heating and extracting after uniformly stirring, then performing ultrasonic treatment, performing ultrasonic centrifugation and taking supernatant to finish the preparation of the feed additive for preventing piglet diarrhea by replacing antibiotics; finally obtaining the feed additive for preventing the piglet diarrhea.

Preferably, the vitamin complex is a mixture of vitamin B, vitamin C and vitamin E, and the ratio of vitamin B to vitamin C to vitamin E is 2:2: 1.

Preferably, in the fifth step, the sweetener is 4% -5% of neotame, and the carrier is anhydrous glucose.

Preferably, in the step five, the frequency of the ultrasonic treatment is 25-40KHz, the ultrasonic power is 1050- & 1250w, and the treatment time is 30-45 min.

Preferably, the addition amount of the feed additive is 0.05-0.2% of the feed, and when the piglets are diarrhea, the addition amount of the feed additive is 0.2-0.35% of the feed.

Compared with the prior art, the invention has the following beneficial effects: the feed additive for preventing the diarrhea of the piglets replaces antibiotics by using Chinese herbal medicines, probiotics and proteins, so that the feed additive has the function of replacing the antibiotics, wherein the compound protein powder can enhance the immunity of the piglets and improve the gastrointestinal flora of the piglets, and in addition, the compound probiotics, the compound vitamins and the montmorillonite are combined, so that the feed additive has the functions of repairing damaged intestinal mucosa, enhancing the digestion and absorption and can effectively prevent the diarrhea of the weaned piglets. The additive has the advantages of convenient collection of raw materials, simple process, convenient operation and low manufacturing cost, can effectively improve the economic benefit of culturists, and has good application prospect.

Detailed Description

In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.