Method for improving resolution of confocal scanning optical imaging image

文档序号:120308 发布日期:2021-10-22 浏览:25次 中文

阅读说明:本技术 一种提高共聚焦扫描光学成像图像分辨率的方法 (Method for improving resolution of confocal scanning optical imaging image ) 是由 李超宏 于 2021-07-15 设计创作,主要内容包括:本发明涉及光学成像系统领域,具体涉及一种提高共聚焦扫描光学成像图像分辨率的方法,包括:共聚焦扫描光学成像通过扫描振镜的快轴和扫描振镜的慢轴进行扫描;从待测物的第一端至第二端的扫描过程中,扫描振镜的快轴的扫描电压为先上升后下降的扫描方式。(The invention relates to the field of optical imaging systems, in particular to a method for improving the resolution of a confocal scanning optical imaging image, which comprises the following steps: scanning is carried out on confocal scanning optical imaging through a fast axis of a scanning galvanometer and a slow axis of the scanning galvanometer; in the scanning process from the first end to the second end of the object to be detected, the scanning voltage of the fast axis of the scanning galvanometer is in a scanning mode of ascending first and then descending.)

1. A method of increasing resolution of a confocal scanning optical imaging image, the method comprising:

scanning is carried out on confocal scanning optical imaging through a fast axis of a scanning galvanometer and a slow axis of the scanning galvanometer;

in the scanning process from the first end to the second end of the object to be detected, the scanning voltage of the fast axis of the scanning galvanometer is in a scanning mode of ascending first and then descending.

2. The method of claim 1, wherein the scanning voltage of the fast axis of the scanning galvanometer is symmetric.

3. The method for improving the resolution of confocal scanning optical imaging images as claimed in claim 1, wherein the scanning voltage and the scanning angle of the fast axis of the scanning galvanometer are proportional.

4. The method for improving the resolution of confocal scanning optical imaging images as claimed in claim 1, wherein the scanning voltage and angle of the slow axis of the scanning galvanometer are proportional.

5. The method of claim 1, wherein the scanning galvanometer is driven by a power source to generate a driving signal.

6. The method of improving resolution of confocal scanning optical imaging images of claim 1, wherein said driving signals are divided into horizontal driving signals and vertical driving signals.

7. The method of claim 6, wherein the horizontal driving signal drives a fast axis of the scanning galvanometer.

8. The method for improving resolution of confocal scanning optical imaging images of claim 6, wherein said vertical drive signal drives the slow axis motion of the scanning galvanometer.

9. A confocal scanning optical imager, said confocal scanning optical imager employing the method of any one of claims 1-8 for improving resolution of confocal scanning optical imaging images.

Technical Field

The invention relates to the field of optical imaging systems, in particular to a method for improving the resolution of a confocal scanning optical imaging image.

Background

At present, most fundus laser confocal scanning imaging adopts a galvanometer as an optical scanning device, for example, patent CN107692963A (a confocal scanning laser ophthalmoscope) as a module shown in fig. 106 is a scanning device in the optical system, laser is focused at different positions of the fundus by scanning of the galvanometer, then the backward scattering light of the fundus returns to be split by a beam splitter 108, part of light enters a module 107, the module 107 contains a pinhole and a detector, thereby completing detection of signals at different positions of the fundus, and finally, the signals are synthesized into a two-dimensional fundus image with a certain range through an algorithm.

At present, based on a galvanometer scanning system, because the distance difference between the fast axis and the slow axis of the galvanometer can cause the pillow-shaped distortion of a scanning area, when the fundus is scanned, the driving voltage of the galvanometer and the scanning angle of the galvanometer meet the linear relation when the galvanometer works, because the distortion is generated, when the fundus is scanned, the length of a scanning line corresponding to the same voltage range is larger, and through the arrangement, the resolution ratio of a central view field image is larger than that of a peripheral view field image.

In view of the above problems, it is desirable to provide an optical method for improving the resolution of a confocal scanning optical imaging image, so as to solve the above technical problem of low peripheral resolution of the image.

Disclosure of Invention

In a first aspect of the present invention, a method for improving the resolution of a confocal scanning optical imaging image is disclosed, which includes:

scanning is carried out on confocal scanning optical imaging through a fast axis of a scanning galvanometer and a slow axis of the scanning galvanometer;

in the scanning process from the first end to the second end of the object to be detected, the scanning voltage of the fast axis of the scanning galvanometer is in a scanning mode of ascending first and then descending.

In a preferred embodiment, the scanning voltage of the fast axis of the scanning galvanometer is in a bilateral symmetry scanning mode.

In a preferred embodiment, the scanning voltage and the angle of the fast axis of the scanning galvanometer are proportional.

In a preferred embodiment, the scanning voltage and the angle of the slow axis of the scanning galvanometer are proportional.

In a preferred embodiment, the scanning galvanometer is driven by a power supply to generate a driving signal.

In a preferred embodiment, the driving signals are divided into horizontal driving signals and vertical driving signals.

In a preferred embodiment, the horizontal drive signal drives the fast axis motion of the scanning galvanometer.

In a preferred embodiment, the vertical drive signal drives the slow axis motion of the scanning galvanometer.

A second aspect of the present invention provides a confocal scanning optical imager, which employs the above method for improving the resolution of the confocal scanning optical imaging image.

Compared with the prior art, the scanning mode of the scanning galvanometer is innovatively designed, and the peripheral resolution of the image can be effectively improved by adopting the scanning mode.

Drawings

FIG. 1 is a schematic diagram of a scanning mode in which the scanning voltage of the fast axis of the scanning galvanometer rises first and then falls.

Figure 2 is a schematic illustration of a pincushion distortion.

Fig. 3 is a schematic diagram of a galvanometer scanning mode in the prior art.

Detailed Description

In order to make the technical solution of the present invention clearer, the technical solution of the present invention is further described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention. It should be noted that the embodiments and features of the embodiments may be combined with each other without conflict.

In a first aspect of the present invention, a method for improving the resolution of a confocal scanning optical imaging image is disclosed, which includes:

scanning is carried out on confocal scanning optical imaging through a fast axis of a scanning galvanometer and a slow axis of the scanning galvanometer;

in the scanning process from the first end to the second end of the image, the scanning voltage of the fast axis of the scanning galvanometer is in a scanning mode of ascending first and then descending.

The term "Confocal scanning optical imaging", abbreviated as "Confocal scanning laser optical imaging" (CSLO), is used for scanning imaging with laser, and has the advantages of fast and simple shooting, little influence from pupil size, and the like.

The confocal scanning optical imaging is taken as an optical scanning device through a scanning galvanometer, the scanning galvanometer is divided into a fast axis and a slow axis, the fast axis of the scanning galvanometer is transverse scanning, and the scanning speed of the scanning galvanometer is higher and is called as the fast axis; the slow axis of the scanning galvanometer is longitudinal scanning, and the scanning speed of the scanning galvanometer is relatively slow and is called as the slow axis. The confocal scanning optical imaging scans an object to be measured through a fast axis of a scanning galvanometer and a slow axis of the scanning galvanometer, and then the whole image is drawn.

As shown in fig. 1, during the scanning process from the first end to the second end of the object, the scanning voltage of the fast axis of the scanning galvanometer is in a first-rising and then-falling scanning mode.

The term "object to be measured" is a generic term of an object to be measured, and may be an image or an object. In the invention, the eye is preferably selected, a confocal scanning optical imager is adopted to shoot the fundus photo, and the resolution of the fundus photo is improved by improving the resolution of the image around the confocal scanning optical imaging, so that the details around the fundus photo are clearer and the eye can be conveniently checked by a doctor.

The term "first end" refers to the starting position of the scan of the test object. In the present invention, the first end generally refers to the upper end of the image, but may refer to the lower end of the image.

The term "second end" refers to the end point of the scan of the test object. In the present invention, the second end generally refers to the lower end of the image, but may refer to the upper end of the image.

The scan lengths of the first and second ends may or may not be the same.

The image obtained by scanning the fundus by the confocal scanning optical imager can be round, rectangular or square.

Based on the mechanical structure of the scanning galvanometer, because a certain distance difference exists between the fast axis and the slow axis of the scanning galvanometer, and meanwhile, in the prior art, the scanning voltage is kept constant, as shown in fig. 3, and the distance difference can cause pincushion distortion to occur in a scanning area, as shown in fig. 2, that is, a scanned image is pincushion. This technical problem was described in the article "pincushion distortion correction algorithm for galvanometer scanning system"; the authors: zhao Yi, Lu inherits the essence; a periodical: chinese laser Vol.30, No.3 is also reported. In order to solve the technical problem that an image obtained by actual scanning in the invention is circular, rectangular or square, peripheral regions of the image, such as 4 corner regions of a pillow shape, occupy the image resolution due to the existence of pillow shape distortion, so that the overall image resolution is reduced, the applicant selects a scanning voltage matched with the scanned image according to the length of the scanned image. In a preferred embodiment, the scanned image is circular or rectangular (the length is smaller than the width), and during the scanning process of the scanning galvanometer from top to bottom, the scanning voltage of the fast axis of the scanning galvanometer is in a scanning mode of firstly rising and then falling.

The scanning voltage of each scanning galvanometer corresponds to the transverse scanning length corresponding to the image, for example, in the process of each transverse scanning, the transverse scanning is ensured to be collected and scanned by 1024 or 2048 times, while in the traditional scanning mode, due to the pillow-shaped distortion, the scanning of the peripheral image is lower than 1024 or 2048 times, the scanning times can be effectively utilized by the method, the scanning times are all adjusted to be within the range of the effective image, and the resolution of the peripheral image is effectively improved.

In a preferred embodiment, the scanning voltage of the fast axis of the scanning galvanometer is in a bilateral symmetry scanning mode.

In a preferred embodiment, the scanning voltage and the angle of the fast axis of the scanning galvanometer are proportional.

In a preferred embodiment, the scanning voltage and the angle of the slow axis of the scanning galvanometer are proportional.

In a preferred embodiment, the scanning galvanometer is driven by a power supply to generate a driving signal.

In a preferred embodiment, the driving signals are divided into horizontal driving signals and vertical driving signals.

In a preferred embodiment, the horizontal drive signal drives the fast axis motion of the scanning galvanometer.

In a preferred embodiment, the vertical drive signal drives the slow axis motion of the scanning galvanometer.

A second aspect of the present invention provides a confocal scanning optical imager, which employs the above method for improving the resolution of the confocal scanning optical imaging image.

Compared with the prior art, the scanning mode of the scanning galvanometer is innovatively designed, and the peripheral resolution of the image can be effectively improved by adopting the scanning mode.

It is to be noted that the foregoing is only illustrative of the preferred embodiments of the present invention and the technical principles employed. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.

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