阅读说明：本技术 一种治疗白血病的药物组合物 (Pharmaceutical composition for treating leukemia ) 是由 张鹏 唐春花 邢宽 何志健 谢珍 倪海钰 周权 何贵伦 安雪茹 李平 江晓琴 于 2020-04-29 设计创作，主要内容包括：本发明公开了一种治疗白血病的药物组合物,由以下重量份的原料组成：生黄茋10-20份、白术5-10份、陈皮5-10重量份、白芍1-9份、青黄散5-8份、梅花点舌丸10-15份。该治疗白血病的药物组合物配方合理,抗癌生血、提高造血能力,减少白细胞的增长,增强体质免疫力,疗效明显,其有效率达到80％以上,没有副作用,而且个组分原料价格低,使得治疗费用低,减轻患者的经济负担。(The invention discloses a pharmaceutical composition for treating leukemia, which comprises the following raw materials in parts by weight: 10-20 parts of radix astragali stilbene, 5-10 parts of rhizoma atractylodis macrocephalae, 5-10 parts of dried orange peel, 1-9 parts of white paeony root, 5-8 parts of green yellow powder and 10-15 parts of plum blossom tongue-dropping pills. The pharmaceutical composition for treating leukemia has reasonable formula, anticancer and hematopoiesis effects, can improve hemopoietic capacity, reduce increase of leucocyte, enhance physique immunity, and has obvious curative effect, the effective rate of the pharmaceutical composition reaches more than 80%, no side effect, and low price of component raw materials, so that the therapeutic cost is low, and the economic burden of patients is relieved.)

1. A pharmaceutical composition for treating leukemia, which is characterized in that: the composition is characterized by comprising the following raw materials in parts by weight:

10-20 parts of radix astragali stilbene, 5-10 parts of rhizoma atractylodis macrocephalae, 5-10 parts of pericarpium citri reticulatae, 1-9 parts of radix paeoniae alba, 5-8 parts of green yellow powder and 10-15 parts of plum blossom tongue-dropping pills.

2. The pharmaceutical composition for treating leukemia according to claim 1, wherein: the main raw materials of the powder are cortex phellodendri and indigo naturalis, and the mass ratio of the cortex phellodendri to the indigo naturalis is 60: 1.

3. The pharmaceutical composition for treating leukemia according to claim 1, wherein: the plum blossom tongue pill comprises the following components in parts by weight:

2-8 parts of white plum blossom, 2-8 parts of toad venom, 1-6 parts of frankincense, 1-6 parts of myrrh, 0.5-4 parts of dragon's blood, 0.7-3 parts of borneol, 1-2 parts of cinnabar, 0.3-2 parts of realgar, 0.6-1 part of abalone shell, 1-1.5 parts of borax, 3-6 parts of agilawood, 4-6 parts of semen lepidii, 2-4 parts of bezoar, 2-5 parts of bear gall, 1-3 parts of musk and 3-9 parts of pearl powder.

4. The pharmaceutical composition for treating leukemia according to claim 1, wherein: the composition is characterized by comprising the following raw materials in parts by weight:

10 parts of radix astragali, 10 parts of rhizoma atractylodis macrocephalae, 10 parts of dried orange peel, 9 parts of white paeony root, 8 parts of green yellow powder and 15 parts of plum blossom tongue-dropping pills.

5. The pharmaceutical composition for treating leukemia according to claim 1, wherein: the composition is characterized by comprising the following raw materials in parts by weight:

15 parts of radix astragali, 8 parts of bighead atractylodes rhizome, 7 parts of dried orange peel, 5 parts of white paeony root, 6 parts of green yellow powder and 12 parts of plum blossom tongue-dropping pills.

6. The pharmaceutical composition for treating leukemia according to claim 1, wherein: the composition is characterized by comprising the following raw materials in parts by weight:

18 parts of radix astragali, 7 parts of rhizoma atractylodis macrocephalae, 8 parts of dried orange peel, 4 parts of white paeony root, 7 parts of green yellow powder and 14 parts of plum blossom tongue-dropping pill.

7. The pharmaceutical composition for treating leukemia according to claim 1, wherein: the composition is characterized by comprising the following raw materials in parts by weight:

20 parts of radix astragali, 5 parts of rhizoma atractylodis macrocephalae, 5 parts of dried orange peel, 1 part of white paeony root, 5 parts of green yellow powder and 10 parts of plum blossom tongue-dropping pills.

Technical Field

The invention belongs to the technical field of biomedical medicines, and particularly relates to a pharmaceutical composition for treating leukemia.

Background

Leukemia (L eukemia) is a malignant tumor of hematopoietic system, and is characterized in that the leukocytes and their immature cells also have the progressive and uncontrolled abnormal proliferation of immature erythrocytes or megakaryocytes (i.e. leukemia cells) in bone marrow or other hematopoietic tissues, infiltrate into various tissues and organs of the whole body, and enter into peripheral blood.

Leukemia has no clear direct etiology, and the pathogenesis is generally considered to be caused by the combined action of genetic factors (internal factors) and environmental factors (external factors). Of all the leukemia causative factors known, chemical exposure (e.g., exposure to dyes, nail varnishes, optical brighteners, dyes, etc., and the administration of certain antineoplastic cytotoxic drugs such as mechlorethamine, cyclophosphamide, etc.), viral infection (e.g., RNA virus infection), radiation injury (e.g., exposure to ionizing radiation), smoking, genetic susceptibility (e.g., chromosomal aberrations) are the most common causes.

The existing treatment means have the problems of poor treatment effect and high cost, so a novel pharmaceutical composition for treating leukemia is needed to solve the problems.

Disclosure of Invention

The present invention aims at providing one kind of medicine composition for treating leukemia to solve the problems of the background technology.

In order to achieve the purpose, the invention provides the following technical scheme: a pharmaceutical composition for treating leukemia comprises the following raw materials in parts by weight:

10-20 parts of radix astragali stilbene, 5-10 parts of rhizoma atractylodis macrocephalae, 5-10 parts of dried orange peel, 1-9 parts of white paeony root, 5-8 parts of green yellow powder and 10-15 parts of plum blossom tongue-dropping pills.

Wherein:

the raw radix astragali stilbene is sweet in taste and slightly warm in nature, and has the following effects: invigorating qi, invigorating yang, invigorating defensive system, consolidating superficial resistance, removing toxic substance, promoting granulation, inducing diuresis, and relieving edema, and can be used for treating spontaneous perspiration, night sweat, blood arthralgia, edema, carbuncle, cellulitis, internal injury, fatigue, spleen deficiency, diarrhea, rectocele, and all the symptoms of qi deficiency and blood deficiency.

Bighead atractylodes rhizome, with bitter taste and mild nature, has the effects of strengthening spleen and supplementing qi, eliminating dampness and promoting diuresis, arresting sweating and preventing miscarriage, and is used for treating spleen deficiency, anorexia, dyspepsia, diarrhea, edema, spontaneous perspiration and threatened abortion.

Tangerine peel, pericarpium Citri Reticulatae is bitter and pungent in flavor, warm in nature, and can regulate qi, invigorate spleen, dry dampness and resolve phlegm, and is indicated for abdominal distention, poor appetite, vomiting and diarrhea, cough and profuse sputum.

Qinghuang san has different degrees of inhibition on L615, S180 cell DNA and RNA.

The plum blossom tongue drop pill has obvious effect of inhibiting leukemia cells.

Preferably, the main raw materials of the powder are golden cypress and natural indigo, and the adding ratio of the golden cypress and the natural indigo is 60: 1.

In any of the above schemes, the preferable composition and weight parts of the plum blossom tongue pill are as follows:

2-8 parts of white plum blossom, 2-8 parts of toad venom, 1-6 parts of frankincense, 1-6 parts of myrrh, 0.5-4 parts of dragon's blood, 0.7-3 parts of borneol, 1-2 parts of cinnabar, 0.3-2 parts of realgar, 0.6-1 part of abalone shell, 1-1.5 parts of borax, 3-6 parts of agilawood, 4-6 parts of semen lepidii, 2-4 parts of bezoar, 2-5 parts of bear gall, 1-3 parts of musk and 3-9 parts of pearl powder.

In any of the above schemes, the composition is preferably prepared from the following raw materials in parts by weight:

10 parts of radix astragali, 10 parts of rhizoma atractylodis macrocephalae, 10 parts of dried orange peel, 9 parts of white paeony root, 8 parts of green yellow powder and 15 parts of plum blossom tongue-dropping pills.

In any of the above schemes, the composition is preferably prepared from the following raw materials in parts by weight:

15 parts of radix astragali, 8 parts of bighead atractylodes rhizome, 7 parts of dried orange peel, 5 parts of white paeony root, 6 parts of green yellow powder and 12 parts of plum blossom tongue-dropping pills.

In any of the above schemes, the composition is preferably prepared from the following raw materials in parts by weight:

18 parts of radix astragali, 7 parts of rhizoma atractylodis macrocephalae, 8 parts of dried orange peel, 4 parts of white paeony root, 7 parts of green yellow powder and 14 parts of plum blossom tongue-dropping pill.

In any of the above schemes, the composition is preferably prepared from the following raw materials in parts by weight:

20 parts of radix astragali, 5 parts of rhizoma atractylodis macrocephalae, 5 parts of dried orange peel, 1 part of white paeony root, 5 parts of green yellow powder and 10 parts of plum blossom tongue-dropping pills.

The invention has the technical effects and advantages that: the pharmaceutical composition for treating leukemia has reasonable formula, anticancer and hematopoiesis effects, can improve hemopoietic capacity, reduce increase of leucocyte, enhance physique immunity, and has obvious curative effect, the effective rate of the pharmaceutical composition reaches more than 80%, no side effect, and low price of component raw materials, so that the therapeutic cost is low, and the economic burden of patients is relieved.

Detailed Description

To further illustrate the technical means and effects of the present invention for achieving the predetermined objects, the following detailed description of the preferred embodiments of the pharmaceutical composition for treating leukemia according to the present invention, methods and effects thereof will be provided.