阅读说明：本技术 一种癌症外用止痛组合物及其制备方法和应用 (External analgesic composition for cancer and preparation method and application thereof ) 是由 李松英 郑金霞 于 2020-04-27 设计创作，主要内容包括：本发明提供一种癌症外用止痛组合物及其制备方法和应用,止痛组合物包括以下重量份数的原料：当归8-20份、丹参8-20份、乳香8-20份、没药8-20份、肉桂8-20份、川乌8-20份、草乌8-20份、壁虎8-15份、蜈蚣5-10份、冰片1-5份。本发明根据恶性肿瘤的病因机理,以“益气扶正、散瘀化结”为原则,选取,使用时外贴/外敷在痛处,或者选穴外贴/外敷,能够有效缓解患者的局部疼痛感,无副作用且不会产生依赖性。(The invention provides an external cancer analgesic composition, a preparation method and application thereof, wherein the analgesic composition comprises the following raw materials in parts by weight: 8-20 parts of angelica, 8-20 parts of salvia miltiorrhiza, 8-20 parts of frankincense, 8-20 parts of myrrh, 8-20 parts of cinnamon, 8-20 parts of monkshood, 8-20 parts of kusnezoff monkshood root, 8-15 parts of gecko, 5-10 parts of centipede and 1-5 parts of borneol. The invention selects the principle of 'tonifying qi and strengthening body resistance, dissipating stasis and removing stasis' according to the etiology and mechanism of malignant tumor, and the external application/external application is carried out at the pain part or selected points, thereby effectively relieving the local pain of a patient without side effect and generating dependence.)

1. The external cancer analgesic composition is characterized by comprising the following raw materials in parts by weight:

8-20 parts of angelica, 8-20 parts of salvia miltiorrhiza, 8-20 parts of frankincense, 8-20 parts of myrrh, 8-20 parts of cinnamon, 8-20 parts of monkshood, 8-20 parts of kusnezoff monkshood root, 8-15 parts of gecko, 5-10 parts of centipede and 1-5 parts of borneol.

2. The external cancer analgesic composition of claim 1, which comprises the following raw materials in parts by weight: 10-15 parts of angelica, 10-15 parts of salvia miltiorrhiza, 10-15 parts of frankincense, 10-15 parts of myrrh, 10-15 parts of cinnamon, 10-15 parts of monkshood, 10-15 parts of kusnezoff monkshood root, 10-12 parts of gecko, 8-10 parts of centipede and 2-3 parts of borneol.

3. A method for preparing the external analgesic composition for cancer as set forth in claim 1, which comprises the steps of: grinding and sieving the raw materials respectively to obtain medicinal powder, and mixing the medicinal powder according to the raw material ratio.

4. The method for preparing a topical analgesic composition for cancer as claimed in claim 3, wherein 100-300 parts of yellow wine is added to the mixed powder and stirred to form a paste.

5. Use of the cancer analgesic composition for external use according to claim 1 or 2 for preparing a cancer analgesic drug.

6. Use of the cancer external analgesic composition as claimed in claim 1 or 2 for preparing a qi-replenishing stasis-dissipating cancer analgesic drug.

7. The use of claim 6, wherein the cancer pain relieving drug is a topical drug, and the topical drug is a paste or patch.

Technical Field

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an external cancer analgesic composition.

Background

Cancer patients often have pain symptoms at the middle and late stages, and the patients are greatly afflicted. At present, most of cancer pain relieving methods are injection or oral pain relieving medicines, and the existing pain relieving medicines can relieve the pain of patients, but have strong side effects, can generate medicine dependence effects and are not suitable for long-term administration.

Disclosure of Invention

Based on the above background problems, the present invention aims to provide an analgesic composition for external use for cancer, which has no side effects, no dependency, and is capable of effectively relieving pain; the invention also aims to provide a preparation method and application of the external cancer analgesic composition.

In one aspect, the embodiment of the invention provides an external cancer analgesic composition, which comprises the following raw materials in parts by weight:

8-20 parts of angelica, 8-20 parts of salvia miltiorrhiza, 8-20 parts of frankincense, 8-20 parts of myrrh, 8-20 parts of cinnamon, 8-20 parts of monkshood, 8-20 parts of kusnezoff monkshood root, 8-15 parts of gecko, 5-10 parts of centipede and 1-5 parts of borneol.

In one embodiment, the external cancer analgesic composition comprises the following raw materials in parts by weight:

10-15 parts of angelica, 10-15 parts of salvia miltiorrhiza, 10-15 parts of frankincense, 10-15 parts of myrrh, 10-15 parts of cinnamon, 10-15 parts of monkshood, 10-15 parts of kusnezoff monkshood root, 10-12 parts of gecko, 8-10 parts of centipede and 2-3 parts of borneol.

The effects of the raw materials selected in the embodiment of the invention are as follows:

chinese angelica: enriching blood, promoting blood circulation, regulating menstruation, relieving pain, loosening bowel to relieve constipation; it can be used for treating blood deficiency, sallow complexion, giddiness, palpitation, menoxenia, amenorrhea, dysmenorrhea, asthenia cold, abdominal pain, rheumatalgia, traumatic injury, superficial infection, pyocutaneous disease, intestinal dryness, and constipation.

Red sage root: promoting blood circulation, removing blood stasis, dredging channels, relieving pain, clearing heart fire, relieving restlessness, cooling blood, and eliminating carbuncle; can be used for treating thoracic obstruction, heart pain, abdominal pain, hypochondriac pain, abdominal mass, pain due to arthralgia, vexation, insomnia, menoxenia, dysmenorrhea, amenorrhea, and pyocutaneous disease with swelling and pain.

Frankincense: promoting blood circulation, promoting qi circulation, relieving pain, eliminating swelling, and promoting granulation; it can be used for treating thoracic obstruction, cardialgia, gastralgia, dysmenorrhea, amenorrhea, puerperal stagnation, abdominal pain, rheumatic arthralgia, spasm of muscles and tendons, traumatic injury, carbuncle, swelling, and pyocutaneous disease.

Myrrh: removing blood stasis, relieving pain, eliminating swelling, and promoting granulation; it can be used for treating thoracic obstruction, cardialgia, gastralgia, dysmenorrhea, amenorrhea, puerperal stagnation, abdominal mass, rheumatic arthralgia, traumatic injury, carbuncle, swelling, and pyocutaneous disease.

Cinnamon: dispel cold to alleviate pain, warm and dredge meridians; can be used for treating sexual impotence, cold womb, lumbago, knee psychroalgia, asthma due to kidney deficiency, floating of deficient yang, giddiness, conjunctival congestion, cold pain of heart and abdomen, vomiting and diarrhea due to deficiency cold, cold hernia, abdominal pain, dysmenorrhea, and amenorrhea.

Radix aconiti: dispelling pathogenic wind, removing dampness, warming channels and relieving pain; it can be used for treating arthralgia due to wind-cold-dampness, arthralgia, psychroalgia of heart and abdomen, cold hernia, and pain due to anesthesia.

Kusnezoff monkshood root: dispelling pathogenic wind, removing dampness, warming channels and relieving pain; it can be used for treating arthralgia due to wind-cold-dampness, arthralgia, psychroalgia of heart and abdomen, cold hernia, and pain due to anesthesia.

Gecko: dispelling pathogenic wind, activating collaterals, resolving hard mass; it can be used for treating apoplexy, paralysis, rheumatic arthralgia, osteomyelitis, lymphoid tuberculosis, esophageal cancer, lung cancer, primary liver cancer, intestinal cancer, etc.

Centipede: calming endogenous wind, relieving spasm, dredging collaterals, relieving pain, removing toxic substances, and resolving hard mass; it can be used for treating stirring of liver-wind, spasm, convulsion, infantile convulsion, and apoplexyHemiplegia, tetanus, stubborn rheumatism, migraine, sore and ulcer, scrofula, snake and insect bite.

Borneol: fragrant dispersion, resuscitation inducing, refreshing, heat clearing, toxic materials removing, eyesight improving, and nebula removing; can be used for treating fever, hyperpyrexia, coma, apoplexy, phlegm syncope, convulsion, summer-heat, dampness, obstruction of the channels, laryngopharyngitis, deafness, aphtha, dental swelling, skin ulcer, carbuncle, hemorrhoid, conjunctival congestion, swelling and pain, nebula, and ophthalmopathy.

The invention is based on the etiology and mechanism of malignant tumor, and based on the principle of 'benefiting qi and strengthening body resistance, dissipating blood stasis and resolving masses', when in use, the external plaster/external application is applied on the pain part or the selected acupoint, the local pain of the patient can be effectively relieved, and the plaster has no side effect and does not generate dependence.

In another aspect, the present invention also provides a method for preparing the above analgesic composition for external use for cancer, comprising the following steps: grinding and sieving the raw materials respectively to obtain medicinal powder, and mixing the medicinal powder according to the raw material ratio.

In one embodiment, 100-300 parts of yellow wine is added into the mixed medicinal powder and stirred to form paste.

In addition, the embodiment of the invention also provides application of the cancer external analgesic composition in preparing a cancer analgesic drug.

Preferably, the application of the cancer external analgesic composition in preparing a qi-tonifying stasis-dissipating cancer analgesic drug is provided.

Preferably, the cancer pain relieving medicine is an external medicine, and the external medicine is an ointment or a patch.

Compared with the prior art, the invention has the following effects:

the traditional Chinese medicine composition has the effects of tonifying qi, strengthening body resistance, dissipating blood stasis and removing stasis through compatibility of medicines, so that the local pain of a patient is effectively relieved, and the traditional Chinese medicine composition has no side effect and cannot generate dependence.

Detailed Description

The invention provides an external cancer analgesic composition, which comprises the following raw materials in parts by weight: 8-20 parts of angelica, 8-20 parts of salvia miltiorrhiza, 8-20 parts of frankincense, 8-20 parts of myrrh, 8-20 parts of cinnamon, 8-20 parts of monkshood, 8-20 parts of kusnezoff monkshood root, 8-15 parts of gecko, 5-10 parts of centipede and 1-5 parts of borneol.

The invention selects the principle of 'tonifying qi and strengthening body resistance, dissipating stasis and removing stasis' according to the etiology and mechanism of malignant tumor, and the external application/external application is carried out at the pain part or selected points, thereby effectively relieving the local pain of a patient without side effect and generating dependence.

The invention will be elucidated by means of specific embodiments.