吡啶羰基衍生物及其作为trpc 6抑制剂的治疗用途
阅读说明:本技术 吡啶羰基衍生物及其作为trpc 6抑制剂的治疗用途 (Pyridinecarbonyl derivatives and their therapeutic use as TRPC6 inhibitors ) 是由 T·布伊苏 D·戈特施林 N·海涅 L·L·史密斯基南 M·D·洛 H·拉扎维 C·R· 于 2018-10-25 设计创作,主要内容包括:本发明涉及式(I)的化合物,<Image he="337" wi="700" file="DDA0002469253940000011.GIF" imgContent="drawing" imgFormat="GIF" orientation="portrait" inline="no"></Image>及其药学上可接受的盐,其中R<Sup>1</Sup>至R<Sup>7</Sup>、A、Y及L如本文所定义。本发明还涉及包含这些化合物的药物组合物、使用这些化合物来治疗各种疾病及病症的方法、用于制备这些化合物的方法以及这些方法中所用的中间体。(The invention relates to compounds of formula (I), and pharmaceutically acceptable salts thereof, wherein R 1 To R 7 A, Y and L are as defined herein. The invention is also directed to pharmaceutical compositions comprising these compounds, to methods of using these compounds to treat various diseases and disorders, to processes for preparing these compounds, and to intermediates used in these processes.)