阅读说明：本技术 一种丝素蛋白美肌护理液及其制备方法 (Silk fibroin skin beautifying care solution and preparation method thereof ) 是由 胡伟 许旭芳 陈耀祖 于 2020-06-18 设计创作，主要内容包括：本发明公开了一种丝素蛋白美肌护理液及其制备方法,由以下重量份数的原料制成：丝素蛋白纳米乳5%-8%、益生菌0.1%-0.5%、抗氧化剂1.0%-5.0%、月桂酰燕麦氨基酸钠25.0%-35.0%、APG表面活性剂5.0%-8.0%、油溶性油脂10%-20%、多元醇溶剂2%-6%、皮肤调理剂0.5%-1.0%、防腐剂0.5%-1%,乳酸0.5%-1%、沉香精油0.5%-1%,余量为纯水,丝素蛋白纳米乳和纳米脂质体四氢姜黄素的协同作用,能有效抑制氧自由基的生成并能清除已经形成的自由基,另外乳酸杆菌和乳酸可以协同调节私处pH值,月桂酰燕麦氨基酸钠和APG癸基葡糖苷协同作用,泡沫柔软丰富,手感温和、舒适,辛酸/癸酸甘油酯、多元醇溶剂、辛酰甘氨酸可以增强保湿性,本发明作为上层乳状、下层水状的护理液,融合身体乳与清洁泡沫双重功能,带来的洁净、滋润、防护的效果。(The invention discloses a silk fibroin skin beautifying care solution and a preparation method thereof, wherein the silk fibroin skin beautifying care solution is prepared from the following raw materials in parts by weight: 5-8% of silk fibroin nanoemulsion, 0.1-0.5% of probiotics, 1.0-5.0% of antioxidant, 25.0-35.0% of sodium lauroyl oat amino acid, 5.0-8.0% of APG surfactant, 10-20% of oil-soluble grease, 2-6% of polyalcohol solvent, 0.5-1.0% of skin conditioner, 0.5-1% of preservative, 0.5-1% of lactic acid, 0.5-1% of agilawood essential oil and the balance of pure water, the synergistic effect of the silk fibroin nanoemulsion and nanoliposome tetrahydrocurcumin can effectively inhibit the generation of oxygen free radicals and eliminate the formed free radicals, in addition, the pH value of a private part can be synergistically adjusted by lactobacillus and lactic acid, the synergistic effect of the sodium lauroyl oat amino acid and APG decyl glucoside is realized, the foam is soft and rich, the hand feeling is mild and comfortable, and caprylic/capric glyceride, The polyhydric alcohol solvent and the caprylyl glycine can enhance the moisture retention, and the lotion is used as a nursing liquid with an upper layer of milky and a lower layer of watery, combines the double functions of body milk and cleaning foam, and brings the effects of cleaning, moistening and protecting.)

1. The silk fibroin skin beautifying care solution is characterized by being prepared from the following raw materials in parts by weight: 5-8% of silk fibroin nanoemulsion, 0.1-0.5% of probiotics, 1.0-5.0% of antioxidant, 25.0-35.0% of sodium lauroyl oat amino acid as foaming component, 5.0-8.0% of APG surfactant, 10-20% of oil-soluble grease, 2-6% of polyalcohol solvent, 0.5-1.0% of skin conditioner, 0.5-1% of preservative, 0.5-1% of lactic acid, 0.5-1% of agilawood essential oil and the balance of pure water.

2. The care solution according to claim 1, characterized in that the probiotic bacteria are lactobacilli.

3. The solution according to claim 1, characterized in that the antioxidant is nanoliposome tetrahydrocurcumin.

4. The solution of claim 1 wherein the APG surfactant is decyl glucoside.

5. The care solution according to claim 1, wherein the oil-soluble oil is caprylic capric glyceride.

6. The care solution according to claim 1, wherein the polyol solvent is a mixture of glycerol, butylene glycol and propylene glycol in a weight ratio of 1:1: 1.

7. The solution of claim 1, wherein the skin conditioning agent is caprylylglycine.

8. The care solution of claim 1, wherein the preservative is a mixture of glyceryl caprylate, caprylyl hydroxamic acid, p-hydroxyacetophenone and butylene glycol in a weight ratio of 1:1:1: 1.

9. A process for preparing a care solution according to any of claims 1 to 8, characterized in that it comprises the following steps:

(1) firstly, adding the lauroyl oat amino acid sodium, decyl glucoside and pure water in the weight fractions into a main stirring kettle, and stirring for 5-10 minutes at the rotating speed of 50-60r/min to prepare a component A;

(2) adding the silk fibroin nanoemulsion, the lactobacillus, the nanoliposome tetrahydrocurcumin, the glyceryl caprylate, the caprylyl hydroxamic acid, the p-hydroxyacetophenone, the butanediol and the agilawood essential oil in parts by weight into a first stirrer, stirring for 5-10 minutes at a rotating speed of 50-60r/min until the mixture is uniformly mixed, and keeping the temperature to be lower than 45 ℃ to prepare a component B;

(3) adding the skin conditioner and the polyalcohol solvent in the weight parts into a second stirrer, heating to 75-80 ℃, and stirring at a rotation speed of 50-60r/min until the mixture is clear and transparent to obtain a component C;

(4) firstly, adding the component B into a main stirring kettle, and continuously stirring for 20-30 minutes at a rotating speed of 50-60 r/min; adding the component C into a main stirring kettle, and continuously stirring for 5-10 minutes at a rotating speed of 50-60 r/min; then adding the oil-soluble grease with the weight fraction into a main stirring kettle, and uniformly stirring for 20-30 minutes at a rotating speed of 50-60 r/min; then adding the lactic acid with the weight fraction into a main stirring kettle, uniformly stirring for 10-15 minutes at the rotating speed of 50-60r/min, uniformly stirring, standing, and discharging.

Technical Field

The invention relates to a care solution, in particular to a silk fibroin skin beautifying care solution and a preparation method thereof.

Background

Women private parts are in moist and sultry environment for a long time, bacteria are easy to breed, so that red swelling, pruritus or inflammation are generated, vaginal flora imbalance and microecological balance problems are solved, the life quality of women is seriously influenced, women in a sub-health state use some nursing liquid products, mild common gynecological diseases of women can be relieved and treated, a firm defense system is built for self health, besides medicinal private part nursing liquid for treating, many types of private part nursing liquid for daily cleaning and health care are derived, the novel private part nursing liquid can clean and moisten the private parts, and the requirement of daily maintenance and nursing is met.

The private skin is delicate and sensitive, the irritation components such as alcohol and spice contained in the general private care solution can cause irritation to the skin, in addition, some products which are claimed to whiten the private parts are on the market, the private parts are turned to be tender by adding tender red, the principle of the product is similar to dyeing, namely the original color is covered and dyed to be pink, so the effect duration of the product is short, skin allergy is easily caused, the product is more harmful to women in pregnancy, lactation and menstrual period, and metabolism is even influenced, and therefore, the private care solution with low sensitivity and safety is necessary to be designed.

Disclosure of Invention

In order to overcome the defects of the prior art, the invention provides a silk fibroin skin beautifying care solution and a preparation method thereof.

The technical scheme adopted by the invention for solving the technical problems is as follows:

the silk fibroin skin beautifying care solution is prepared from the following raw materials in parts by weight: 5-8% of silk fibroin nanoemulsion, 0.1-0.5% of probiotics, 1.0-5.0% of antioxidant, 25.0-35.0% of sodium lauroyl oat amino acid as foaming component, 5.0-8.0% of APG surfactant, 10-20% of oil-soluble grease, 2-6% of polyalcohol solvent, 0.5-1.0% of skin conditioner, 0.5-1% of preservative, 0.5-1% of lactic acid, 0.5-1% of agilawood essential oil and the balance of pure water.

The probiotic is lactobacillus.

The antioxidant is nanoliposome tetrahydrocurcumin.

The APG surfactant is decyl glucoside.

The oil-soluble grease is caprylic capric glyceride.

The polyalcohol solvent is a mixture of glycerol, butanediol and propylene glycol in a weight ratio of 1:1: 1.

The skin conditioner is caprylyl glycine.

The preservative is a mixture of glyceryl caprylate, caprylyl hydroxamic acid, p-hydroxyacetophenone and butanediol in a weight ratio of 1:1:1: 1.

A method for preparing the silk fibroin skin beautifying care solution comprises the following steps:

(1) firstly, adding the lauroyl oat amino acid sodium, decyl glucoside and pure water in the weight fractions into a main stirring kettle, and stirring for 5-10 minutes at the rotating speed of 50-60r/min to prepare a component A;

(2) adding the silk fibroin nanoemulsion, the lactobacillus, the nanoliposome tetrahydrocurcumin, the glyceryl caprylate, the caprylyl hydroxamic acid, the p-hydroxyacetophenone, the butanediol and the agilawood essential oil in parts by weight into a first stirrer, stirring for 5-10 minutes at a rotating speed of 50-60r/min until the mixture is uniformly mixed, and keeping the temperature to be lower than 45 ℃ to prepare a component B;

(3) adding the skin conditioner and the polyalcohol solvent in the weight parts into a second stirrer, heating to 75-80 ℃, and stirring at a rotation speed of 50-60r/min until the mixture is clear and transparent under visual observation and has no impurities to obtain a component C;

(4) firstly, adding the component B into a main stirring kettle, and continuously stirring for 20-30 minutes at a rotating speed of 50-60 r/min; adding the component C into a main stirring kettle, and continuously stirring for 5-10 minutes at a rotating speed of 50-60 r/min; then adding the oil-soluble grease with the weight fraction into a main stirring kettle, and uniformly stirring for 20-30 minutes at a rotating speed of 50-60 r/min; then adding the lactic acid with the weight fraction into a main stirring kettle, uniformly stirring for 10-15 minutes at the rotating speed of 50-60r/min, uniformly stirring, standing still, and preparing the upper-layer milky care solution and the lower-layer aqueous care solution.

The invention has the beneficial effects that: the silk fibroin nano-emulsion and the nanoliposome tetrahydrocurcumin have synergistic effect, can effectively inhibit the generation of oxygen free radicals and can clear formed free radicals, has obvious antioxidation, in addition, lactobacillus and lactic acid can synergistically regulate the pH value of a private part and improve the microecological balance of skin, and lauroyl sodium aveoaminate and APG decyl glucoside have synergistic effect, so that the foam is soft and rich, the hand feeling is mild and comfortable, and the caprylic/capric glyceride, the polyalcohol solvent and the caprylyl glycine can enhance the moisture retention property.

Detailed Description

The following examples further illustrate the practice and advantages of the present invention, and should not be construed as limiting the scope of the invention.

In the present example, the temperature and pressure are not particularly emphasized, and both are normal temperature and normal pressure.

The silk fibroin nanoemulsion is silk fibroin processed by a nanotechnology, and the preparation method of the silk fibroin nanoemulsion comprises the following steps: adding the silk fibroin solution with the molecular weight of below 40kDa into an oil phase, uniformly mixing, wherein the ratio of the silk fibroin solution to the oil phase is 1:20 to obtain a colostrum solution, and then carrying out homogeneous active microjet treatment on the colostrum solution to obtain the silk fibroin nanoemulsion.

The probiotics are lactobacillus which is obtained from plants and separated from rice made in Japan, is known as the most important probiotic member in normal flora of vagina and plays a key role in maintaining self-cleaning and resisting infection of vagina.

The antioxidant is nanoliposome tetrahydrocurcumin, is obtained by hydrogenating curcumin separated from rhizome of Curcuma longa of Zingiberaceae, has strong activity of inhibiting tyrosinase, can effectively inhibit generation of oxygen free radicals and remove formed free radicals, and has obvious antioxidation effect.

The sodium lauroyl oat amino acid is an amino acid surfactant, has strong foaming power and hard water resistance, can form cream foam, and is mild and comfortable.

The APG surfactant is decyl glucoside, which is one of novel nonionic surfactants APG, has the characteristics of common nonionic and anionic surfactants, is extracted from plants, has low irritation and stability, and ensures that the finished product has rich, fine and stable foam.

The oil-soluble grease is caprylic acid/capric acid glyceride, can be used as a base material of moisturizing factors, is easily absorbed by skin, enables the skin to be smooth and glossy, and plays a good role in the uniformity and fineness of cosmetics.

The polyalcohol solvent is glycerol, butanediol, and propylene glycol, and can enhance moisture retention, and polyalcohol also has great influence on appearance property and stability of final product.

The skin conditioner is caprylyl glycine, has good affinity to skin, has good antibacterial effect, has strong inhibiting effect on staphylococcus aureus, propionibacterium acnes and the like, and can effectively inhibit the activation of elastase, prevent the decomposition of elastin, reduce skin wrinkles and regulate the secretion of skin oil.

The antiseptic is one or mixture of two or more of glyceryl caprylate, caprylyl hydroximic acid, p-hydroxyacetophenone and butanediol, and has low irritation to skin, good antibacterial property, and improved moisture keeping effect.

The agilawood essential oil (produced by Guangzhou national Wei Biotechnology Co., Ltd.) is precious agilawood volatile oil obtained by distilling agilawood and is a natural perfume, researches show that valerenic acid contained in the agilawood has obvious tranquilizing and allaying excitement activity, alpha-santalol and agarol have chlorpromazine-like stabilizing effect, and atractylol has activities of improving cerebral blood circulation, metabolism and the like.