阅读说明：本技术 一种离子风产生装置及其应用 (Ion wind generating device and application thereof ) 是由 龚涛 钟伦超 钱翔 唐飞 王晓浩 于 2020-04-20 设计创作，主要内容包括：本申请属于物质分析技术领域,特别是涉及一种离子风产生装置及其应用。传统的离子源的分析方法是把有机物在固体表面利用区位提取技术先将固体表面的有机物进行提取到液相,然后选择合适的方法进行分析。这种方法费时费力,同时在提取的过程中也很难保证有机物在固体表面上的准确的分布。本申请提供了一种离子风产生装置,包括离子风产生组件和气体放电组件,所述离子风产生组件与所述气体放电组件连接；所述离子风产生组件包括第一电极和第二电极,所述第一电极包括若干放电针,所述第一电极与所述气体放电组件连接,所述第二电极与所述气体放电组件连接。可以实现在大气压下多个放电针的同时电晕放电,大大增加了随之产生的离子风数量。(The application belongs to the technical field of material analysis, and particularly relates to an ion wind generation device and application thereof. The traditional ion source analysis method is to extract organic matters on the solid surface to a liquid phase by utilizing a zone extraction technology on the solid surface, and then, a proper method is selected for analysis. This method is time consuming and laborious and it is difficult to ensure accurate distribution of the organic matter on the solid surface during the extraction process. The application provides an ion wind generating device, which comprises an ion wind generating assembly and a gas discharging assembly, wherein the ion wind generating assembly is connected with the gas discharging assembly; the ion wind generation assembly comprises a first electrode and a second electrode, the first electrode comprises a plurality of discharge needles, the first electrode is connected with the gas discharge assembly, and the second electrode is connected with the gas discharge assembly. The corona discharge can be realized at the same time of a plurality of discharge needles under the atmospheric pressure, and the quantity of the ion wind generated therewith is greatly increased.)

1. An ion wind generating device, characterized in that: the device comprises an ion wind generating assembly and a gas discharging assembly, wherein the ion wind generating assembly is connected with the gas discharging assembly;

the ion wind generation assembly comprises a first electrode and a second electrode, the first electrode comprises a plurality of discharge needles, the first electrode is connected with the gas discharge assembly, and the second electrode is connected with the gas discharge assembly.

2. The ionic wind generating apparatus according to claim 1, wherein: the first electrode is in a shape of a crown, and the second electrode is in a shape of a net.

3. The ionic wind generating apparatus according to claim 2, wherein: the first electrode is arranged at one end of the ion wind generating assembly, the second electrode is arranged at the other end of the ion wind generating assembly, the second electrode is a stainless steel net, and the first electrode is cylindrical.

4. The ionic wind generating apparatus according to claim 2, wherein: the first electrode comprises a circular ring and tooth tips, the tooth tips are arranged on the circular ring, the diameter of the circular ring is 21.4 millimeters, and the number of the tooth tips is 40.

5. The ionic wind generating apparatus according to claim 3, wherein: the first electrode may be slip fit.

6. The ionic wind generating device according to any one of claims 1 to 5, further comprising: the ion wind generation assembly is 60 millimeters in inner diameter and 60 millimeters in length, and is a cylindrical cavity.

7. The ionic wind generating apparatus according to claim 6, wherein: the gas discharge assembly comprises a cathode crown, a ballast resistor, a direct-current high-voltage power supply, a test resistor and an anode ring which are sequentially connected, the direct-current high-voltage power supply is connected with the discharge resistor, the ballast resistor, the discharge resistor and the test resistor are sequentially connected, the test resistor is connected with an oscilloscope, the discharge resistor, the oscilloscope and the anode ring are connected, the first electrode is connected with the cathode crown, and the second electrode is connected with the anode ring.

8. The ionic wind generating apparatus according to claim 6, wherein: the wind speed of the ion wind generated by the ion wind generating device is 1.1 m/s.

9. Use of an ion wind generating device, characterized by: the ion wind generating device is applied to a mass spectrometer.

Technical Field

The application belongs to the technical field of material analysis, and particularly relates to an ion wind generation device and application thereof.

Background

High-field asymmetric waveform ion mobility spectrometry (FAIMS) is a characteristic that separation and detection of different chemical species are realized by the change of ion mobility along with the change of electric field intensity. The FAIMS system mainly comprises three components of an ion source, a migration area and a detection area. The ion source is a technology for ionizing a sample into ions, has important functions on subsequent analysis, analysis and detection, and is a very important component in a FAMIS system. The FAMIS technology provides a possible differential ion mobility spectrometry for the rapid detection of substances in the atmospheric environment, and is a new technology for rapidly separating and identifying gas-phase ions in the atmospheric environment.

Based on the characteristic that the nonlinear change of ion mobility is highlighted under a high field, an asymmetric high electric field is constructed in the ion advancing direction, and a spectrogram is generated by utilizing scanning electric field compensation voltage and ion signals, so that gas-phase trace substance detection for separating and identifying substance ions is carried out. After research and development of scientific research and commercial institutions of various countries for several decades, the technology has become one of the mainstream gas phase detection means, and is widely used for biological medicine of explosives and drugs, environmental monitoring and the like.

The traditional ion source analysis method is to extract organic matters on the solid surface to a liquid phase by utilizing a zone extraction technology on the solid surface, and then, a proper method is selected for analysis. This method is time consuming and laborious and it is difficult to ensure accurate distribution of the organic matter on the solid surface during the extraction process.

Disclosure of Invention

1. Technical problem to be solved

The traditional ion source-based analysis method is characterized in that organic matters on the solid surface are extracted into a liquid phase by utilizing a zone extraction technology on the solid surface, and then an appropriate method is selected for analysis. The method is time-consuming and labor-consuming, and meanwhile, the problem that the accurate distribution of organic matters on the surface of the solid is difficult to ensure in the extraction process is solved.

2. Technical scheme

In order to achieve the above object, the present application provides an ion wind generating apparatus, comprising an ion wind generating assembly and a gas discharge assembly, wherein the ion wind generating assembly is connected with the gas discharge assembly;

the ion wind generation assembly comprises a first electrode and a second electrode, the first electrode comprises a plurality of discharge needles, the first electrode is connected with the gas discharge assembly, and the second electrode is connected with the gas discharge assembly.

Another embodiment provided by the present application is: the first electrode is in a shape of a crown, and the second electrode is in a shape of a net.

Another embodiment provided by the present application is: the first electrode is arranged at one end of the ion wind generating assembly, the second electrode is arranged at the other end of the ion wind generating assembly, the second electrode is a stainless steel net, and the first electrode is cylindrical.

Another embodiment provided by the present application is: the first electrode comprises a circular ring and tooth tips, the tooth tips are arranged on the circular ring, the diameter of the circular ring is 21.4 millimeters, and the number of the tooth tips is 40.

Another embodiment provided by the present application is: the first electrode may be slip fit.

Another embodiment provided by the present application is: the ion wind generation assembly is 60 millimeters in inner diameter and 60 millimeters in length, and is a cylindrical cavity.

Another embodiment provided by the present application is: the gas discharge assembly comprises a cathode crown, a ballast resistor, a direct-current high-voltage power supply, a test resistor and an anode ring which are sequentially connected, the direct-current high-voltage power supply is connected with the discharge resistor, the ballast resistor, the discharge resistor and the test resistor are sequentially connected, the test resistor is connected with an oscilloscope, the discharge resistor, the oscilloscope and the anode ring are connected, the first electrode is connected with the cathode crown, and the second electrode is connected with the anode ring.

Another embodiment provided by the present application is: the wind speed of the ion wind generated by the ion wind generating device is 1.1 m/s.

The application also provides an application of the ion wind generating device, and the ion wind generating device is applied to a mass spectrometer.

3. Advantageous effects

Compared with the prior art, the ionic wind generating device and the application thereof have the beneficial effects that:

the ion wind generating device provided by the application can be operated under the environment of atmospheric pressure, and is the biggest characteristic of a novel direct ion source, and the analysis method does not need to carry out a complex pretreatment process on a sample, so that the ion wind generating device has the characteristics of simplicity in operation, quickness and the like. Based on the advantages, the ion source can be applied to the in-situ analysis of solid surface samples, and target molecules can be directly extracted in a complex matrix.

The application provides an ion wind generating device, designs a needle-net discharge ion source through the gas discharge principle, realizes under open atmospheric pressure environment, and the research is carried out to the discharge characteristic of needle-net ion source.

The application of the ion wind generating device provided by the application can complete ionization of a sample as an ion source, and meanwhile, ions of the sample can enter the mass analyzer from the ion source along with the flow of ion wind, so that the ion source and the sample introduction system are combined into a whole, the size of a mass spectrometer is reduced, the process of mass spectrometry is simplified, and the ion wind generating device is expected to be applied to a miniaturized and portable mass spectrometer.

Drawings

FIG. 1 is a schematic structural view of an ion wind generating assembly according to the present application;

FIG. 2 is a schematic view of a gas discharge assembly according to the present application;

FIG. 3 is a schematic diagram of the glow corona state of the present application;

in the figure: the device comprises a 1-ion wind generating assembly, a 2-gas discharging assembly, a 3-first electrode, a 4-second electrode, a 5-cathode crown, a 6-ballast resistor, a 7-direct current high-voltage power supply, an 8-test resistor, a 9-anode ring, a 10-discharging resistor and an 11-oscilloscope.

Detailed Description

Hereinafter, specific embodiments of the present application will be described in detail with reference to the accompanying drawings, and it will be apparent to those skilled in the art from this detailed description that the present application can be practiced. Features from different embodiments may be combined to yield new embodiments, or certain features may be substituted for certain embodiments to yield yet further preferred embodiments, without departing from the principles of the present application.

FAIMS systems may employ different ion source designs, such as electrospray ionization sources, vacuum ultraviolet lamp ion sources, and electrospray ion sources, among others. Although radioactive ion sources have the advantages of simplicity, no need for power supplies, and the like, the disadvantages of purchase, transportation, and scrapping seriously affect their application in FAIMS systems. Therefore, no radioactive ion source is selected in our system. Although the ultraviolet lamp ion source and the laser desorption ion source have the advantages of no radioactive pollution, stable work and the like, the ultraviolet lamp ion source and the laser desorption ion source are large in size and cannot be processed by an MEMS. The commonly used ultraviolet lamp can provide photon energy at 10.6eV, and only can ionize substances with ionization energy lower than 10.6eV, and the application range is relatively narrow. The electrospray ion source has obvious advantages, substances capable of being ionized are wide, but the electrospray ionization source can not work without solvents, water molecules exist along with the substances and are difficult to eliminate, and the influence on the FAIMS work is huge. The ion source of the vacuum ultraviolet lamp has the characteristics of less fragments, stable performance and the like, but the ionization energy of the ion source is low, and only substances with lower ionization energy can be ionized.

Referring to fig. 1 to 3, the present application provides an ion wind generating device, including an ion wind generating assembly 1 and a gas discharge assembly 2, where the ion wind generating assembly 1 is connected to the gas discharge assembly 2;

the ion wind generation assembly 1 comprises a first electrode 3 and a second electrode 4, the first electrode 1 comprises a plurality of discharge needles, the first electrode 3 is connected with the gas discharge assembly 2, and the second electrode 4 is connected with the gas discharge assembly 2.

Further, the first electrode 3 is in a shape of a crown, and the second electrode 4 is in a shape of a net.

Further, the first electrode 3 is disposed at one end of the ion wind generating assembly 1, the second electrode 4 is disposed at the other end of the ion wind generating assembly 1, the second electrode 4 is a stainless steel mesh, and the first electrode 3 is cylindrical.

Further, the first electrode 3 comprises a circular ring and 40 tooth tips, wherein the tooth tips are arranged on the circular ring, the diameter of the circular ring is 21.4 millimeters, and the number of the tooth tips is 40.

Further, the first electrode 3 may be slip-fitted.

Further, the ion wind generating assembly 1 has an inner diameter of 60mm and a length of 60mm, and is a cylindrical cavity.

Further, the gas discharge assembly 2 comprises a cathode crown 5, a ballast resistor 6, a direct-current high-voltage power supply 7, a test resistor 8 and an anode ring 9 which are connected in sequence, the direct-current high-voltage power supply 7 is connected with a discharge resistor 10, the ballast resistor 6, the discharge resistor 10 and the test resistor 8 are connected in sequence, the test resistor 8 is connected with an oscilloscope 11, the discharge resistor 10 and the oscilloscope 11 are connected with the anode ring 9, the first electrode 3 is connected with the cathode crown 5, and the second electrode 4 is connected with the anode ring 9.

And a direct-current high-voltage power supply 7 of 0-5 kv is adopted to supply power to the system. As shown in fig. 2, the voltage-current signal was measured by connecting a 100 Ω test resistor 8 in series with the external circuit and observed using an oscilloscope 11(Tektronix TDS1001B,40 MHz). The applied high voltage direct current signal passes through a high voltage probe (Tektronix P6015A,1000X) and then is input into an oscilloscope 11.

Further, the wind speed of the ion wind generated by the ion wind generating device is 1.1 m/s.

The present application provides the use of an ion wind generating device for application to a mass spectrometer.

And optimized parameter values are obtained through designed experiments, so that the efficiency of the method can be maximized in practical application. In the experimental process, in order to facilitate air intake, 40 teeth are machined on a circular ring with the diameter of 21.4mm by using a precision machining method to form a crown structure, each tooth tip is used as a discharge needle, namely the first electrode 3, and the whole circular ring also meets the structural requirement of multiple needles. The whole ion wind generating assembly 1 is structurally designed into a cylindrical cavity with the inner diameter of 60mm and the length of 60mm, a stainless steel net is installed at one end of the cavity to serve as an anode, and a cylindrical structure capable of being matched in a sliding mode is designed at the other end of the cavity and used for adjusting the distance between the multi-needle structure and the anode net. An ion wind device is shown in fig. 1.

Since gas discharge is the basis of generation of ion wind in the entire apparatus, whether stable corona discharge can be obtained is important for generation of ion wind. By utilizing the process principle of observing corona and spark discharge, on one hand, a discharge point can be observed through a darkroom experiment, on the other hand, the oscilloscope 11 can be connected in a circuit, and the discharge phenomenon can be indirectly observed by observing the change of the oscilloscope 11.

It can be seen from the darkroom that the conversion from corona discharge to spark discharge requires several stages of development: at the beginning, the discharge needle, namely the space between the first electrode 3 and the stainless steel mesh, namely the second electrode 4, is not accompanied with luminescence, and is in a dark current state; as the voltage rises at the cathode, i.e. the first electrode 3, and at the anode, i.e. the second electrode 4, a purple light spot is observed by the naked eye, which is the glow corona of the gas discharge, when a current of the order of microamperes passes, after which a brush-like light-emitting beam is pulsed from the needle end; as the voltage rises again, the discharge in the corona emitting region will become a current flow column. When the voltage of the discharge needle is adjusted to be about-4310V, purple light spots appear near the discharge needle, namely, the discharge needle is in a glow corona state.

The device can realize corona discharge of a plurality of discharge needles under atmospheric pressure, thereby greatly increasing the quantity of ion wind generated therewith. Through measurement, the highest wind speed of the ion wind generated by the device can reach 1.1 m/s. Meanwhile, as is well known, the structure of the mass spectrometer is divided into a sample introduction system, an ion source, a mass analyzer and the like, the ion wind device provided by the application not only can be used as the ion source to complete ionization of a sample, but also can enable the sample ions to be introduced into the mass analyzer from the ion source along with the flowing of the ion wind, so that the ion source and the sample introduction system are combined into a whole, the size of the mass spectrometer is reduced, the process of mass spectrometry is simplified, and the mass spectrometer is expected to be applied to the miniaturized and portable mass spectrometer.

A High-field Asymmetric Waveform ion mobility Spectrometry (FAIMS) has the advantages of High speed, low power consumption, High sensitivity, portability and the like, and is receiving more and more attention in the field of substance detection. The basic principle is as follows: and detecting the concentration and the type of the substance according to the difference of the mobility of the ions under the radio frequency high-voltage electric field. For detecting low concentrations of gases, typical FAIMS systems can generally detect signal strengths on the order of pA. In the process of high-sensitivity detection, a multi-needle-net corona discharge structure is provided, and the multi-needle-net corona discharge structure is favorably applied to portable analytical instruments such as FAIMS, a mass spectrometer, ion mobility spectrometry and the like, so that the dual effects of an open type micro air pump and an ion source are realized, and the miniaturization of the ion source is a key technology for the miniaturization, integration and functionalization of the analytical instruments. The needle net integrated high-field asymmetric waveform ion system consists of an ionization region, a migration region and an ion detection region. The ion source is made of a mesh structure, ions are focused towards the middle of the polar plate before entering the migration zone under the action of the focusing electrode in the ionization zone, ion loss is reduced, the intensity of detection current is improved, and the defect that the conventional flat-plate FAIMS cannot realize ion focusing is overcome to a certain extent. Under the open atmospheric environment, stable corona discharge can be realized by applying controllable negative direct current voltage to the net through multiple needles, so that ionization of substances is realized. And the ion wind with certain flow rate generated by corona discharge can simultaneously realize the dual effects of sample introduction of the sample wafer and ion driving after ionization of substances. A high-field asymmetric square wave radio frequency power supply is adopted to provide working voltage for a FAIMS chip migration area, and the amplitude and the frequency of the high-field asymmetric square wave radio frequency power supply can meet the requirements of a miniature FAIMS chip on high-field asymmetric voltage waveforms. The ion detection area of the designed FAIMS chip adopts a cylindrical array type micro Faraday cylinder, has the characteristics of large gas receiving area, sufficient ion absorption, capability of working in an atmospheric pressure environment, integration with the FAIMS chip and the like, can detect positive and negative ions simultaneously, and can realize the functions of ion separation and filtration.

Common asymmetric structures are needle-plate structures, concentric spheres, thread-plate structures, and thread-barrel structures. Corona ion sources of pin-plate construction have found a great number of applications in IMS (ion mobility spectrometry). The ion wind design of the multi-needle-net structure can combine an ion source and a sample introduction system in the traditional mass spectrometer, thereby simplifying the process of mass spectrometry, reducing the volume of the mass spectrometer and being expected to be applied to a portable mass spectrometer for real-time on-line analysis. The ion wind with a multi-needle-net structure can mainly complete two functions of discharging and sample feeding. As a discharge cell, an ion wind of a "multi-pin-mesh" structure generates ions mainly by gas discharge. It is mainly composed of a plurality of discharge needles and a net. The mechanical mechanism of the discharge device is very important for the discharge of the electrode and the generation of ion wind, and in this structure, the precision of the electrode has a great influence on the discharge. It has been demonstrated that an asymmetric "pin-plate" structure can operate stably in atmospheric pressure conditions to achieve corona discharge to produce ionic wind. In order to generate ion wind and obtain larger wind speed, we use the design of multiple discharge needles to discharge to one plane at the same time, and the wind speed of the ion wind is expected to be multiplied. In order to achieve the purpose, the most important thing is to ensure the parallelism between the plane of the needle points of the discharge needles and the plane of the mesh, otherwise, as the voltage applied to the discharge needles gradually increases, the discharge needles nearest to the mesh will start to discharge firstly, and other discharge needles do not reach the discharge condition, so that the requirement of simultaneous discharge of multiple needles cannot be met, and the wind speed of the ion wind cannot be increased. Therefore, the needle point of the discharge needle and the flatness of the net have higher precision requirement.

The ion wind with a multi-needle-net structure can mainly complete two functions of discharging and sample feeding. As a discharge cell, an ion wind of a "multi-pin-mesh" structure generates ions mainly by gas discharge. The asymmetric needle-plate structure can stably work under the atmospheric pressure environment, so that the corona discharge is realized to generate ion wind. In order to facilitate air intake, a plurality of teeth are machined on the circular ring by a precision machining method to form a crown structure, each tooth tip is used as a discharge needle, and the whole circular ring also meets the structural requirement of multiple needles. The whole ion wind device is structurally designed into a cylindrical cavity, a stainless steel net is installed at one end of the cavity to serve as an anode, and a cylindrical structure capable of being matched in a sliding mode is designed at the other end of the cavity and used for adjusting the distance between the multi-needle structure and the anode net.

Although the present application has been described above with reference to specific embodiments, those skilled in the art will recognize that many changes may be made in the configuration and details of the present application within the principles and scope of the present application. The scope of protection of the application is determined by the appended claims, and all changes that come within the meaning and range of equivalency of the technical features are intended to be embraced therein.