阅读说明：本技术 一种改善月经疼痛的植物提取组合物 (Plant extract composition for improving menstrual pain ) 是由 殷世清 王桂波 吴海燕 于 2019-12-23 设计创作，主要内容包括：本发明提供了一种改善月经疼痛的植物提取组合物,该组合物由如下重量份的原料制成：丁香花提取物5-15份,艾草提取物10-20份,快乐鼠尾草提取物10-20份。本发明所述的改善月经疼痛的植物提取组合物,具有改善行经前后或月经期出现下腹部疼痛、坠胀、腰酸或其他不适,改善生活质量。(The invention provides a plant extract composition for improving menstrual pain, which is prepared from the following raw materials in parts by weight: 5-15 parts of clove flower extract, 10-20 parts of wormwood extract and 10-20 parts of clary sage extract. The plant extract composition for improving menstrual pain disclosed by the invention has the effects of improving lower abdominal pain, sagging distention, waist soreness or other discomforts before and after menstruation or during menstruation and improving the quality of life.)

1. A phytoextraction composition for ameliorating menstrual cramping comprising: the composition is prepared from the following raw materials in parts by weight:

5-15 parts of a clove flower extract,

15-20 parts of a wormwood extract,

10-20 parts of salvia sclarea extract.

2. The phytoextraction composition for ameliorating menstrual pain according to claim 1, wherein: the composition is prepared from the following raw materials in parts by weight:

5-15 parts of a clove flower extract,

10-20 parts of a wormwood extract,

10-20 parts of salvia sclarea extract.

3. The phytoextraction composition for ameliorating menstrual pain according to claim 1, wherein: the composition is prepared from the following raw materials in parts by weight:

10-15 parts of a clove flower extract,

15-18 parts of a wormwood extract,

15-20 parts of salvia sclarea extract.

4. The phytoextraction composition for ameliorating menstrual pain according to claim 2, wherein: the composition is prepared from the following raw materials in parts by weight:

10 parts of a clove flower extract, namely,

15 parts of a wormwood extract, namely 15 parts of,

15 parts of clary sage extract.

5. The method for preparing a plant extract composition for relieving menstrual pain according to any one of claims 1 to 4, wherein: the method comprises the following steps: and uniformly mixing the clove extract, the wormwood extract and the clary sage extract to obtain the composition.

6. The method for preparing a plant extract composition for relieving menstrual pain according to claim 5, wherein: the clove flower extract is prepared by the method comprising the following steps: vacuum freeze drying flos Caryophylli, pulverizing, sieving with 60 mesh sieve, and sieving with CO₂Supercritical extraction process for CO regulation₂The circulation flow is 22L/h, the extraction temperature is 40 ℃, the extraction pressure is 10MPa, the extraction is carried out for 4 hours, ethanol is used as an entrainer, the mass concentration is 60 percent, and the extraction product and CO are separated₂Evacuation of CO₂And obtaining the clove flower extract.

7. The method for preparing a plant extract composition for relieving menstrual pain according to claim 5, wherein: performing vacuum freeze-drying on wormwood, crushing, sieving by using a 60-mesh sieve, adopting a CO2 supercritical extraction process, adjusting the circulation flow of CO2 to be 20L/h, the extraction temperature to be 35 ℃, the extraction pressure to be 16MPa, extracting for 80 minutes, using ethanol as an entrainer with the mass concentration of 60%, separating an extraction product from CO2, and emptying CO2 to obtain the wormwood extract.

8. The method for preparing a plant extract composition for relieving menstrual pain according to claim 5, wherein: the clary sage extract is prepared by the method comprising the following steps: taking clary sage particles of 40-60 meshes, distilling for 1.5h, with a material-liquid ratio of 1:8, soaking for 1.5h, and extracting with 2% (w/w) NaCl as a distillation aid for 30s under the assistance of microwave to obtain a clary sage extract extracted by steam distillation.

Technical Field

The invention belongs to the field of plant compositions, and particularly relates to a plant extract composition for improving menstrual pain.

Background

Primary dysmenorrhea is one of the most common gynecological diseases, and brings serious influence on physical and mental health and work and study of women, so that effective prevention and treatment of primary dysmenorrhea is a problem facing the medical interface. The etiology of primary dysmenorrhea is complex, and researchers at home and abroad have more and more researches on pathogenesis and treatment in recent years. Modern medicine has the defects of more adverse reactions and the like in the process of treating dysmenorrhea, and the traditional Chinese medicine has unique advantages in the aspect of treating primary dysmenorrhea.

The incidence of the current dysmenorrhea in China is 33.1%, wherein the primary dysmenorrhea accounts for 53.2%, the incidence of severe dysmenorrhea is 13.55%, the work and life quality of patients are seriously affected to different degrees, western medicine clinical treatment medicines mainly take non-steroidal anti-inflammatory drugs, oral contraceptives, calcium ion antagonists and β -receptor agonists can also be used for relieving symptoms, but the medicines have adverse reactions and clinical application limitations to different degrees, and the conventional treatment has a failure rate of about 20% -25% as reported by literature.

Disclosure of Invention

In view of the above, the present invention aims to provide a plant extract composition for relieving menstrual pain, which is applied to relieve menstrual pain, can be transdermally absorbed easily, has no side effects, and can be used for a long time.

In order to achieve the purpose, the technical scheme of the invention is realized as follows:

a plant extract composition for improving menstrual pain is prepared from the following raw materials in parts by weight:

5-15 parts of a clove flower extract,

15-20 parts of a wormwood extract,

10-20 parts of salvia sclarea extract.

Preferably, the composition is prepared from the following raw materials in parts by weight:

5-15 parts of a clove flower extract,

10-20 parts of a wormwood extract,

10-20 parts of salvia sclarea extract.

3. The phytoextraction composition for ameliorating menstrual pain according to claim 1, wherein: the composition is prepared from the following raw materials in parts by weight:

10-15 parts of a clove flower extract,

15-18 parts of a wormwood extract,

15-20 parts of salvia sclarea extract.

Preferably, the composition is prepared from the following raw materials in parts by weight:

10 parts of a clove flower extract, namely,

15 parts of a wormwood extract, namely 15 parts of,

15 parts of clary sage extract.

The preparation method of the plant extract composition for improving menstrual pain comprises the following steps: and uniformly mixing the clove extract, the wormwood extract and the clary sage extract to obtain the composition.

Further, the clove flower extract is prepared by the method comprising the following steps: by using CO₂The supercritical extraction process comprises vacuum lyophilizing flos Caryophylli, pulverizing, sieving with 60 mesh sieve, and extracting with CO₂Supercritical extraction process for CO regulation₂The circulation flow is 22L/h, the extraction temperature is 40 ℃, the extraction pressure is 10MPa, the extraction is carried out for 4 hours, ethanol is used as an entrainer, the mass concentration is 60 percent, and the extraction product and CO are separated₂Evacuation of CO₂And obtaining the clove flower extract.

Further, the wormwood extract is prepared by the method comprising the following steps: the method comprises the steps of adopting a CO2 supercritical extraction process, carrying out vacuum freeze-drying on the wormwood, crushing, sieving by a 60-mesh sieve, adopting a CO2 supercritical extraction process, adjusting the circulation flow of CO2 to be 20L/h, the extraction temperature to be 35 ℃, the extraction pressure to be 16MPa, extracting for 80 minutes, using ethanol as an entrainer with the mass concentration of 60%, separating an extraction product and CO2, and exhausting CO2 to obtain the wormwood extract.

Further, the clary sage extract is prepared by the method comprising the following steps: the method comprises extracting clary sage granules with steam of 40-60 meshes for 1.5h under the condition of material-liquid ratio of 1:8, soaking for 1.5h, distilling with 2% (w/w) NaCl as auxiliary agent, and extracting with microwave for 30 s. To obtain the clary sage extract extracted by steam distillation.

Clove flower extract: has good functions of sterilizing, easing pain, promoting digestion and the like, plays an indispensable role in medical operations and spices, can be disinfected and eased by clove for a long time by dentists, can promote uterine contraction and reduce fear during menstruation.

The wormwood extract: has the effects of regulating qi and blood, warming channels, dispelling cold and dampness, and relieving pain. Can promote abdominal blood circulation, has good menstruation inducing effect, and can relieve dysmenorrhea caused by cold womb.

Clary sage extract: contains female hormone, is helpful for female reproductive system, is a good tonic for balancing uterus and hormone, and has effects of caring uterus, relieving premenstrual syndrome, regulating dysmenorrhea and hypomenorrhea, promoting menstrual cycle regularity, and further improving conception probability.

The using method comprises the following steps:

relieving physiological syndrome: taking 5 drops of extract in the morning and evening, adding appropriate amount of base oil, massaging the waist, Shenshu, Mingmen and Baliao parts, massaging the abdomen, strengthening the part below the navel, and kneading until fever occurs (the use is suspended in 1-6 days when menstruation comes)

In severe menstrual pain: apply 10 drops of the extract, apply the essential oil directly to the thumb, and then, Rou and an on Weizhong and Chengshan acupoints, and conduct the two feet simultaneously for about 3 minutes.

Relieving pain: applying 5 drops of the extract every week on a hot towel or electric blanket for hot compress for 15-20 min.

Compared with the prior art, the plant extract composition for improving menstrual pain has the following advantages:

(1) the plant extract composition for improving menstrual pain has the advantages of super-strong permeability, high absorption rate and 100% safety. The gel can penetrate into skin and human body internal circulation without chemical residue, has small molecular structure, is more acceptable to skin, and can penetrate into skin dermis and subcutaneous tissue in 3-5 seconds; enters the blood and lymphatic system of the human body for 4 to 12 hours for a week around the human body after 5 to 8 minutes, and is freely discharged out of the human body with the toxin. The stimulating component has the effects of repairing and regenerating, eliminating various bad molecules of obstacle face cells, and most importantly, the stimulating component is natural, pure and free of side effects, and can be safely and safely used for a long time.

(2) The plant extract composition for improving menstrual pain has the effects of rejuvenation, resisting aging, fading spots, promoting cell regeneration, repairing pits and scars, and is beneficial to wound healing, pore shrinking and skin tightening.

Detailed Description

Unless defined otherwise, technical terms used in the following examples have the same meanings as commonly understood by one of ordinary skill in the art to which the present invention belongs. The test reagents used in the following examples, unless otherwise specified, are all conventional biochemical reagents; the experimental methods are conventional methods unless otherwise specified.

The present invention will be described in detail with reference to examples.