阅读说明：本技术 一种消毒泡腾片及其制备方法和应用 (Disinfection effervescent tablet and preparation method and application thereof ) 是由 刘昕 欧海航 许景致 彭小珍 王弋 于 2019-10-17 设计创作，主要内容包括：本发明属于消毒杀菌的技术领域,涉及一种消毒泡腾片及其制备方法和应用。本发明的消毒泡腾片的组分包括单过硫酸氢钾、有机酸、碳酸盐以及泡腾片辅料；还提供了一种消毒泡腾片的制备方法如下：1)溶解：将单过硫酸氢钾、有机酸、碳酸盐以及泡腾片辅料组分于醇类试剂中溶解并分散均匀,形成混合溶剂；2)干燥：烘干混合溶剂形成干燥的结块；3)磨粉：将结块进行冷却碾压、磨粉过筛,形成均质的粉料,将粉料进行压片即得泡腾片；本发明的消毒泡腾片的使用简单方便,放入水中可在短时间内实现完全溶解,不会产生残留物,形成片剂能够降低运输、搬运和贮存的成本,还能够防止因调整必要的浓度或剂量导致的浪费。(The invention belongs to the technical field of disinfection and sterilization, and relates to a disinfection effervescent tablet and a preparation method and application thereof. The components of the disinfection effervescent tablet comprise potassium monopersulfate, organic acid, carbonate and effervescent tablet auxiliary materials; also provides a preparation method of the disinfection effervescent tablet, which comprises the following steps: 1) dissolving: dissolving potassium monopersulfate, organic acid, carbonate and effervescent tablet auxiliary material components in an alcohol reagent, and uniformly dispersing to form a mixed solvent; 2) and (3) drying: drying the mixed solvent to form a dried cake; 3) grinding: cooling and rolling the agglomerates, grinding and sieving to form homogeneous powder, and tabletting the powder to obtain effervescent tablets; the disinfectant effervescent tablet is simple and convenient to use, can be completely dissolved in water in a short time without generating residues, can reduce the transportation, transportation and storage costs by forming the tablet, and can prevent waste caused by adjusting necessary concentration or dosage.)

1. A disinfection effervescent tablet is characterized in that the components of the disinfection effervescent tablet comprise potassium monopersulfate, organic acid, carbonate and effervescent tablet auxiliary materials.

2. A disinfecting effervescent tablet as claimed in claim 1, wherein the components include, by weight, 20-50% of potassium monopersulfate, 10-45% of organic acid, 5-25% of carbonate, and the balance up to 100% of effervescent tablet excipients.

3. A disinfecting effervescent tablet as claimed in claim 1 or claim 2, wherein the organic acid comprises sulfanilic acid and adipic acid-based compound containing adipic acid groups.

4. A disinfecting effervescent tablet as claimed in claim 1 or claim 2, wherein the effervescent tablet excipients include adhesives, flavoring agents, toners, surfactants and stabilizers.

5. A disinfecting effervescent tablet as claimed in claim 4, wherein the adhesive comprises one or a combination of polystyrene pyrrolidone and hydroxypropyl methylcellulose.

6. The effervescent disinfecting tablet of claim 4, wherein the surfactant comprises one or a combination of sulfamate, α -olefin sulfonate.

7. A disinfecting effervescent tablet as claimed in claim 4, wherein the stabilizer comprises one or both of hexametaphosphate and sodium chloride.

8. The preparation method of the disinfection effervescent tablet is characterized by comprising the following steps:

1) dissolving: dissolving potassium monopersulfate, organic acid, carbonate and effervescent tablet auxiliary material components in an alcohol reagent, and uniformly dispersing to form a mixed solvent;

2) and (3) drying: drying the mixed solvent to form a dried cake;

3) grinding: cooling and rolling the agglomerates, grinding and sieving to form homogeneous powder, and tabletting the powder to obtain the effervescent tablets.

9. The preparation method of the disinfection effervescent tablet as claimed in claim 8, wherein the cooling temperature range of the cooling and rolling in the step 3) is 0-10 ℃.

10. An effervescent disinfectant tablet as claimed in any one of claims 1 to 7 for use in disinfection and destruction of bacteria including Streptococcus suis type 2, Escherichia coli, Trichophyton mentagrophytes Salmonella typhimurium, viruses including classical swine fever virus, avian influenza virus, porcine reproductive respiratory syndrome virus, canine parvovirus, and parasites including Trichomonas molitorum.

Technical Field

The invention belongs to the technical field of disinfection and sterilization, and particularly relates to a disinfection effervescent tablet and a preparation method and application thereof.

Background

Potassium monopersulfate is a novel disinfectant of non-chlorine composite active oxygen, and the molecular formula of the novel disinfectant is KHSO₅The molecular structure is shown in FIG. 1.

The foaming bactericide is carbon dioxide (CO)₂) The micropollution gas generator of (1) in a purified manner, by dissolving the main component and other auxiliary components (in the form of tablets), allows the organic acid to dissolve itself when in contact with water, while decomposing carbonates. On the other hand, potassium monoperoxysulfate compounds are generally a disinfectant, have a function of a strong chlorine-free (non-chlorine) oxidizing agent in industry, and are applicable to various fields. Such as tanning chemical adjuvants (tanning chemicals), denture cleaners, swimming pool disinfectants (swimming pool oxidants), circuit board etchants (circuit board etchants) and the like in leather manufacturing processes. In addition, potassium monoperoxysulphate compounds may also find application in veterinary (veterinary) medicine.

Disclosure of Invention

In view of the above problems, the present invention aims to provide a disinfection effervescent tablet, a preparation method and an application thereof.

The technical content of the invention is as follows:

a disinfection effervescent tablet comprises potassium monopersulfate, organic acid, carbonate and effervescent tablet auxiliary materials, wherein the potassium monopersulfate has a main disinfection and sterilization effect, and the organic acid and the carbonate are main components generated by bubbles;

the effervescent tablet comprises, by weight, 20-50% of potassium monopersulfate, 10-45% of organic acid, 5-25% of carbonate and the balance of effervescent tablet auxiliary materials to 100%.

Further, the air conditioner is provided with a fan,

the organic acid comprises sulfanilic acid and adipic acid compounds containing adipic acid groups, including adipic acid;

the effervescent tablet auxiliary materials comprise an adhesive, a flavoring agent, a toner, a surfactant and a stabilizer;

the adhesive comprises one or a combination of polystyrene pyrrolidone and hydroxypropyl methyl cellulose;

the surfactant comprises one or a combination of sulfamate and α -olefin sulfonate, and comprises sodium sulfamate and α -olefin sodium sulfonate;

the stabilizer comprises hexametaphosphate (sodium hexametaphosphate) and sodium chloride, wherein the sodium chloride also has the function of serving as an oxidation auxiliary agent, and has certain stability in a solid state when being used as the stabilizer and is stably stored by combining solid peroxide; as sodium chloride, when dissolved in water, it charges the solution and promotes the decomposition of the oxide.

The invention also provides a preparation method of the disinfection effervescent tablet, which comprises the following steps:

1) dissolving: dissolving potassium monopersulfate, organic acid, carbonate and effervescent tablet auxiliary material components in an alcohol reagent, and uniformly dispersing to form a mixed solvent;

2) and (3) drying: drying the mixed solvent to form a dried cake;

3) grinding: cooling and rolling the agglomerates, grinding and sieving to form homogeneous powder, and tabletting the powder to obtain effervescent tablets;

the cooling temperature range of the cooling and rolling in the step 3) is 0-10 ℃, the cooling and rolling operation is to cool the rolling roller by using cold water at 0-10 ℃, and the rolling roller after cooling is used for rolling the lumps, so that the active ingredients are not easy to decompose, and the active ingredients are kept.

The invention also provides a disinfection effervescent tablet which can be applied to disinfection and killing of bacteria, viruses, mycoplasma and parasites, wherein the bacteria comprise streptococcus suis type 2, escherichia coli, trichophyton mentagrophytes, salmonella typhimurium and the like, the viruses comprise classical swine fever viruses, avian influenza viruses, porcine reproductive and respiratory syndrome viruses, canine parvoviruses and the like, and the parasites comprise trichomonas and the like.

The invention has the following beneficial effects:

the components of the disinfection effervescent tablet comprise the surfactant which can promote the dissolution of potassium monopersulfate, accelerate the reaction of effective components and avoid incomplete dissolution, the stabilizer in the components is used for maintaining the stable existence of the potassium monopersulfate and preventing the potassium monopersulfate from losing efficacy, and the adhesive in the components can effectively bond each component, so that the effervescent tablet is stable, and can be quickly dissolved in water and does not remain when being used;

the disinfectant effervescent tablet is simple and convenient to use, can be completely dissolved in water in a short time without generating residues, can reduce the transportation, transportation and storage costs by forming the tablet, and can prevent waste caused by adjusting necessary concentration or dosage.

Drawings

FIG. 1 is a molecular structure diagram of potassium monopersulfate.

Detailed Description

The present invention is described in further detail in the following description of specific embodiments and the accompanying drawings, it is to be understood that these embodiments are merely illustrative of the present invention and are not intended to limit the scope of the invention, which is defined by the appended claims, and modifications thereof by those skilled in the art after reading this disclosure that are equivalent to the above described embodiments.

All the raw materials and reagents of the invention are conventional market raw materials and reagents unless otherwise specified.