阅读说明：本技术 一种采血装置 (Blood sampling device ) 是由 许铭飞 顾问 杜利军 耿天放 邓冠华 张宇彬 陈仕勇 罗江兰 卢旭玲 于 2019-09-26 设计创作，主要内容包括：本发明公开一种适用于微量血样收集的多功能采血装置,包括采血管和密封件；密封件安装在采血管上,通过该密封件实现静脉穿刺真空采血；采血管分为采血部和收集部,采血部设有导血管口,导血管口设有外缘和引流斜坡导引液体进入收集部收集；收集部的底部闭合。本发明在密封件与采血管连接时用于采集静脉血,在采血部与密封件分离时,实现末梢采血,因此能够同时满足静脉采血和末梢采血的需求,且能够与现有的自动化贴标和上机仪器匹配,实现了多功能采血和标准化处理。(The invention discloses a multifunctional blood collecting device suitable for collecting a trace amount of blood samples, which comprises a blood collecting tube and a sealing piece, wherein the blood collecting tube is provided with a sealing groove; the sealing element is arranged on the blood collection tube, and the venipuncture vacuum blood collection is realized through the sealing element; the blood collection tube is divided into a blood collection part and a collection part, the blood collection part is provided with a blood guide tube opening, and the blood guide tube opening is provided with an outer edge and a drainage slope to guide liquid to enter the collection part for collection; the bottom of the collecting part is closed. The sealing piece is used for collecting venous blood when the sealing piece is connected with the blood collection tube, and peripheral blood collection is realized when the blood collection part is separated from the sealing piece, so that the requirements of venous blood collection and peripheral blood collection can be met simultaneously, the sealing piece can be matched with the existing automatic labeling and on-machine instrument, and multifunctional blood collection and standardized treatment are realized.)

1. A lancing device, comprising a lancing tube and a seal; the blood collection tube is divided into a blood collection part and a collection part, the blood collection part is provided with a blood guide tube opening, the blood guide tube opening is provided with an outer edge and a drainage slope, and liquid is guided to enter the collection part for collection; the sealing element is arranged on the blood collection tube, when the vein blood collection is carried out, the puncture end of the test tube of the blood collection needle punctures the sealing element, and the blood is guided into the collection part through the puncture needle; the bottom of the collecting part is closed.

2. The blood collection device according to claim 1, wherein the outer edge of the blood collection part is subjected to softening treatment of a chamfer or fillet, the angle of the chamfer or fillet is 30 ° to 60 °, and the length of the corner edge of the chamfer or fillet is in the range of 0.1mm to 1 mm; the length of the blood guide tube opening is 0.5mm to 2 mm.

3. The lancing device according to claim 2, wherein the collection portion comprises an upper test tube section and an inner tube, the upper test tube section comprising a sealing area; the inner pipe comprises an arc-shaped pipe section, an inner pipe body and an inner pipe bottom; the blood sampling device is also provided with an outer tube positioned outside the inner tube, the outer tube comprises an outer tube body and an outer tube bottom, and the length of the arc-shaped tube section is 5mm-30mm and is used for connecting the outer tube body and the inner tube body.

4. The lancing device according to claim 3, wherein the inner tube is a hollow member closed at the bottom; the outer pipe is a hollow part, and the bottom of the outer pipe is closed or not closed; the closed end of inner tube and the closed end of outer tube are hemisphere or parabola shape or arc, the outer tube is transparent material, the surface of outer tube sets up the window, the window is geometry's breach, the length of window is at 3mm to 60 mm.

5. The blood collecting device according to claim 4, wherein the inner tube and the outer tube are of an integral structure or a split structure, the bottom of the inner tube and the bottom of the outer tube are closed, and the inner bottom of the outer tube limits the movement of the inner tube through adhesion or buckling, so that the inner tube is fixed; the inner pipe and the outer pipe are of split structures; the inner pipe interface is positioned at the joint of the arc-shaped pipe section and the upper section of the test tube, and the outer pipe interface is positioned at the part of the upper section of the outer pipe body, which is close to the pipe edge; the inner pipe and the outer pipe are detachably connected through threads or aligned clamping grooves.

6. The lancing device according to claim 2, wherein the contact surface of the lancing portion is a hydrophilic contact surface.

7. The blood sampling device according to any one of claims 1 to 6, wherein the sealing member is an independent elastic member or a combination of an elastic member and a safety cap, the elastic member is disposed inside the safety cap or used as an independent accessory, a through hole is disposed at one end of the safety cap, the center of the through hole coincides with the axis of the safety cap, the through hole is cylindrical or truncated cone-shaped, the diameter of the through hole is 4mm to 8mm, an anti-slip region is disposed on the outer surface of the safety cap, the length of the anti-slip region is 5mm to 12mm, and the anti-slip region is provided with vertical lines, horizontal lines or diagonal lines.

8. The blood sampling device according to claim 7, wherein the outer surface of the elastic member is provided with a sealing groove, the outer edge of the blood sampling tube is in fit connection with the sealing groove, the safety cap of the sealing member is provided with internal threads, the outer wall of the upper section of the test tube of the blood sampling tube is provided with external threads, and the sealing member is in threaded connection with the blood sampling tube; elastic component one end can seal the sealed region of heparin tube test tube upper segment, is provided with the shrinkage pool on the elastic component, the shrinkage pool is parabola shape or arc, the shrinkage pool diameter is 4mm to 8mm, sealed region's length is 3mm to 10mm, the material of elastic component is butyl rubber, brominated butyl rubber or thermoplastic polyurethane elastomer rubber.

9. The lancing device according to claim 8, wherein the lancing device has a specification of 13mm x 50mm, 13mm x 75mm and 13mm x 100mm, is adaptable to an automatic test apparatus, and can perform a blood test in a closed environment, and the amount of the collected blood is in a range of 0.1ml to 2.5 ml.

10. The blood collection device according to claim 8, wherein the material of the blood collection tube is selected from one of cycloolefin copolymer, polyethylene terephthalate, polyethylene, polycarbonate and polypropylene plastic material, the inside of the blood collection tube is added with an additive, the additive is an anticoagulant or a coagulant, the anticoagulant comprises EDTA salt, heparin salt, citrate and double oxalate, the coagulant comprises silica and thrombin, the wall thickness of the inner tube is 0.6mm to 1.2mm, and the diameter of the inner tube body is 5mm to 10 mm.

Technical Field

The invention relates to the technical field of blood collection, in particular to a multifunctional blood collecting device suitable for collecting a trace amount of blood samples.

Background

In recent years, with the development of medical technology, the application of vacuum blood collection test tubes in clinical blood tests is also increasingly widespread. According to clinical needs, vacuum blood collection tube according to the additive difference can be divided into many kinds, such as ethylenediamine tetraacetic acid (EDTA) anticoagulation tube, heparin tube, hemagglutination tube, procoagulant tube etc.. In the process of implementing the invention, the inventor finds that the prior art has at least the following problems:

in the clinical diagnosis and treatment process, due to the needs of various blood tests and monitoring treatment effects, a clinical laboratory usually needs to draw a large amount of blood from a patient, but in actual operation, there are still many blood sampling obstacles, such as a small sample size, hemolysis, blood splashing, excessive residual negative pressure and the like, which are not favorable for the normal operation of clinical detection.

The existing blood sampling modes include venous blood sampling, arterial blood sampling and peripheral blood sampling, wherein the venous blood sampling is the most common, and the vacuum blood sampling tube is used for carrying out the venous blood sampling, so that the sufficient blood sampling amount can be ensured, and the interference of other substances such as tissue fluid on a detection result can be avoided. However, for some special groups with anemia or difficulty in collecting venous blood, the vacuum blood collection tube cannot achieve a good effect in blood collection, and blood hemolysis is often caused by excessive residual negative pressure in the tube, so that the detection progress is influenced. For the infant group, because of the particularity of blood vessels and blood cells, it is difficult to ensure that enough venous blood is collected, and excessive blood collection even easily causes iatrogenic anemia, so that peripheral blood collection is still clinically needed at present.

It is worth mentioning that the common micro-tip tube is difficult to match the requirements of the existing automatic labeling and on-machine instruments, a large amount of manual operations are often needed, the blood sampling efficiency is affected, and the repeated uncovering is easy to cause biological pollution, however, the currently used vacuum blood sampling tube cannot simultaneously meet the requirements of vein and tip blood sampling.

Disclosure of Invention

Aiming at the problems, the invention provides a blood sampling device which can meet the requirements of vein and peripheral blood sampling at the same time, can be matched with the existing automatic labeling and machine loading instruments, reduces manual uncovering operation and reduces biological pollution.

The invention provides a blood sampling device, which comprises a blood sampling tube and a sealing piece; the blood collection tube is divided into a blood collection part and a collection part, the blood collection part is provided with a blood guide tube opening, the blood guide tube opening is provided with an outer edge and a drainage slope, and liquid is guided to enter the collection part for collection; the sealing element is arranged on the blood collection tube, when the vein blood collection is carried out, the puncture end of the test tube of the blood collection needle punctures the sealing element, and the blood is guided into the collection part through the puncture needle; the bottom of the collecting part is closed.

Further, the outer edge of the blood sampling part is subjected to softening treatment of a chamfer or a fillet, the angle of the chamfer or the fillet is 30-60 degrees, and the length range of the corner edge of the chamfer or the fillet is 0.1-1 mm; the length of the blood guide tube opening is 0.5mm to 2 mm.

Further, the collecting part comprises an upper test tube section and an inner tube, the upper test tube section comprises a sealing area; the inner pipe comprises an arc-shaped pipe section, an inner pipe body and an inner pipe bottom; the blood sampling device is also provided with an outer tube positioned outside the inner tube, the outer tube comprises an outer tube body and an outer tube bottom, and the length of the arc-shaped tube section is 5mm-30mm and is used for connecting the outer tube body and the inner tube body.

Further, the inner pipe is a hollow part with a closed bottom; the outer pipe is a hollow part, and the bottom of the outer pipe is closed or not closed; the closed end of inner tube and the closed end of outer tube are hemisphere or parabola shape or arc, the outer tube is transparent material, the surface of outer tube sets up the window, the window is geometry's breach, the length of window is at 3mm to 60 mm.

Furthermore, the inner pipe and the outer pipe are of an integrated structure or a split structure, the bottom of the inner pipe and the bottom of the outer pipe are closed, and the inner bottom of the outer pipe limits the movement of the inner pipe through adhesion or buckling, so that the inner pipe is fixed; the inner pipe and the outer pipe are of split structures; the inner pipe interface is positioned at the joint of the arc-shaped pipe section and the upper section of the test tube, and the outer pipe interface is positioned at the part of the upper section of the outer pipe body, which is close to the pipe edge; the inner pipe and the outer pipe are detachably connected through threads or aligned clamping grooves.

Further, the contact surface of the blood collection part is a hydrophilic contact surface.

Further, the sealing member is the combination of elastic component alone or elastic component and safety helmet, the elastic component sets up the inside of safety helmet or as the accessory of independent utility, safety helmet one end is provided with the through-hole, the center of through-hole with the axis coincidence of safety helmet, the through-hole is cylindrical or round platform shape, the through-hole diameter is 4mm to 8mm, and the surface of the safety helmet of sealing member sets up anti-skidding region, the regional length of antiskid is 5mm to 12mm, and anti-skidding region sets up stria, stria or twill.

Furthermore, a sealing groove is formed in the outer surface of the elastic piece, the outer edge of the blood collection tube is connected with the sealing groove in a matched mode, an internal thread is formed in a safety cap of the sealing piece, an external thread is formed in the outer wall of the upper section of the test tube of the blood collection tube, and the sealing piece is connected with the blood collection tube through the thread; elastic component one end can seal the sealed region of heparin tube test tube upper segment, is provided with the shrinkage pool on the elastic component, the shrinkage pool is parabola shape or arc, the shrinkage pool diameter is 4mm to 8mm, sealed region's length is 3mm to 10mm, the material of elastic component is butyl rubber (IIR), brominated butyl rubber (BIIR) or thermoplastic polyurethane elastomer rubber (TPU).

Furthermore, the specification of the blood sampling device comprises 13mm multiplied by 50mm, 13mm multiplied by 75mm and 13mm multiplied by 100mm, the blood sampling device can be matched with automatic detection equipment, blood testing in a closed environment can be realized, and the vacuum blood sampling amount of the collecting part ranges from 0.1ml to 2.5 ml.

Further, the material of the blood collection tube is selected from one of Cyclo Olefin Copolymer (COC), polyethylene terephthalate (PET), Polyethylene (PE), Polycarbonate (PC) and polypropylene (PP) plastic materials, an additive is added inside the blood collection tube, the additive is an anticoagulant or a coagulant, the anticoagulant comprises EDTA salt, heparin salt, citrate, double oxalate and the like, the coagulant comprises silica and thrombin, the wall thickness of the inner tube is 0.6mm to 1.2mm, and the diameter of the inner tube body is 5mm to 10 mm.

The invention has the beneficial effects that: the invention is a blood sampling device, can meet the requirement of blood sampling of vein and end, mainly used for storing and analyzing the pretreatment of the sample collected clinically, the blood sampling tube has remedied the defect of clinical blood sampling to a great extent, such as the problem of insufficient blood sampling amount, excessive residual negative pressure, blood splash, blood sampling obstacle of children, etc., have provided the more efficient solution for clinical blood collection; the blood collection tube is matched with the existing automatic labeling and loading instrument, manual uncovering operation is reduced, biological pollution is reduced, the arc-shaped tube section can prevent a probe of the instrument from deviating to hit the tube wall, the probe is protected, and the phenomenon of blood wall hanging on the upper section of the test tube can be reduced.

Drawings

FIG. 1 is a schematic view of a vacuum blood collection device according to one embodiment of the present invention;

FIG. 2 is a schematic view of a distal blood collection device according to an embodiment of the present invention;

fig. 3 is a schematic structural view of a split blood collection tube according to an embodiment of the present invention;

FIG. 4 is a schematic structural view of an interference fit seal according to an embodiment of the present invention;

FIG. 5 is a schematic view of a thread form seal according to a second embodiment of the present invention;

wherein: 1-safety cap, 2-blood collection tube, 3-upper test tube section, 4-arc tube section, 5-window, 6-inner tube body, 7-outer tube body, 8-sealing piece, 9-additive, 10-bottom inner tube body, 11-outer edge, 12-blood guide tube opening, 13-drainage slope, 14-silicified contact surface, 15-outer wall thread, 16-sealing area, 17-inner tube interface, 18-outer tube interface, 19-outer tube bottom, 20-anti-skid area, 21-concave hole, 22-top plug, 23-through hole, 24-elastic piece, 25-sealing groove, 26-inner tube and 27-outer tube.

Detailed Description

In order to further understand the present invention, the following detailed description will be made with reference to the following examples, which are only used for explaining the present invention and are not to be construed as limiting the scope of the present invention.

In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted" and "connected" are to be interpreted broadly, e.g., as being either fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, so to speak, as communicating between the two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art. The technical solution of the present invention is further described below with reference to the accompanying drawings and examples.

Other features and advantages of the present invention will be described in more detail in the following examples, which are provided for the purpose of further illustrating the invention and are not intended to limit the scope of the invention.

Embodiment 1 of the blood collecting device of the present invention:

as shown in fig. 1 and 2, a blood collecting device includes a blood collecting tube 2 and a sealing member 8; the sealing member 8 is mounted on the blood collection tube 2; the blood collection tube 2 is divided into a blood collection part and a collection part, the blood collection part is provided with a blood guide tube opening 12, the blood guide tube opening 12 is provided with an outer edge 11 and a drainage slope 13, and liquid is guided to enter the collection part for collection; when the vein is used for blood sampling, the puncture end of the test tube of the blood taking needle pierces the sealing element 8, and the blood is guided into the collection part through the puncture needle; the bottom of the collecting part is closed, and the collecting part can be used for collecting venous blood or supplementing peripheral blood after insufficient venous blood collection and pre-treating blood samples after blood collection.

The outer edge 11 of the blood sampling part is subjected to softening treatment of a chamfer or a fillet, the angle of the chamfer or the fillet is 30-60 degrees, the length range of the corner edge of the chamfer or the fillet is 0.1-1 mm, 1-2 chamfers or fillets are arranged on the outer edge 11, and the softened outer edge 11 can prevent the blood sampling part from being scratched in the blood sampling process; the length of the blood guide tube opening 12 is 0.5 mm-2 mm, and anticoagulant can be sprayed at the blood guide tube opening 12, so that blood is prevented from being accidentally coagulated in the blood collecting process.

The collecting portion comprises an upper test tube section 3 and an inner tube 26, the upper test tube section 3 comprising a sealing area 16; the inner pipe 26 comprises an arc-shaped pipe section 4, an inner pipe body 6 and an inner pipe bottom 10; the blood collection device is further provided with an outer tube 27 located outside the inner tube 26, the outer tube 27 comprising an outer tube body 7 and an outer tube bottom 19.

The inner tube 26 is a hollow member with a closed bottom; the outer pipe 27 is a hollow piece, and the bottom of the outer pipe 27 is closed or not closed; the closed ends of the inner tube 26 and the outer tube 27 are hemispherical, parabolic or arcuate.

The length of the arc-shaped pipe section 4 is 5mm-30mm and is used for connecting the outer pipe body 7 and the inner pipe body 6, and the arc-shaped pipe section 4 can prevent the probe of the instrument from deviating and colliding with the pipe wall and plays a role in protecting the probe.

Inner tube 26 and outer tube 27 formula structure as an organic whole, the socle of outer tube can be the straight cylindric of non-closed binding off, constitutes the integral type structure with the inner tube, matches the dimensional requirement of current test tube instrument to the test tube outer wall when being favorable to protecting the inner tube.

The inner tube bottom 10 and the outer tube bottom 19 are closed, and the inner bottom of the outer tube 27 restricts the movement of the inner tube by adhesion or snap-fit, thereby fixing the inner tube 26.

The contact surface of the blood sampling part is a hydrophilic contact surface.

The specification of the blood sampling device comprises 13mm multiplied by 50mm, 13mm multiplied by 75mm and 13mm multiplied by 100mm, and the vacuum blood sampling amount of the collection part ranges from 0.1ml to 2.5 ml.

Preferably, outer tube 27 is transparent material, outer tube 27's surface sets up window 5, window 5 is geometry's breach, and the breach shape can be selected to rectangular shape, circular or oval etc. the length of window 5 is at 3mm to 60mm for including the visual observation of the blood of gathering including the blood sampling scale.

Preferably, the material of the tube body of the blood collection tube 2 is selected from one of Cyclic Olefin Copolymer (COC), polyethylene terephthalate (PET), Polyethylene (PE), Polycarbonate (PC) and polypropylene (PP) plastic materials.

Preferably, the inside of the blood collection tube 2 is added with an additive 9, the additive is uniformly distributed on the inner wall of the device, the additive 9 is an anticoagulant or a coagulant, the anticoagulant comprises EDTA salt, heparin salt, citrate, double oxalate and the like, and the coagulant comprises silicon dioxide, thrombin and the like.

Preferably, the wall thickness of the inner tube 26 and the outer tube 27 of the blood collection tube 2 is 0.6mm to 1.2mm, the diameter of the inner tube body 6 is 5mm to 10mm, the diameter of the inner tube of the blood collection tube 2 is reduced, the liquid level height of blood can be effectively raised, and the liquid level height of enough blood is raised between 10mm to 30 mm. Outer body 7 size and the conventional blood sampling test tube of heparin tube 2 are unanimous, outer body 7 can match current instrument anchor clamps, and outer tube 27 is smooth transparent material, can match automatic subsides mark system.

Embodiment 2 of the blood collecting device of the present invention:

as shown in fig. 1 to 3, a blood collecting device includes a blood collecting tube 2 and a sealing member 8; the sealing member 8 is mounted on the blood collection tube 2; the blood collection tube 2 is divided into a blood collection part and a collection part, the blood collection part is provided with a blood guide tube opening 12, and the blood guide tube opening 12 is provided with an outer edge 11 and a drainage slope 13 to guide liquid to enter the collection part for collection; when the vein is used for blood sampling, the puncture end of the test tube of the blood taking needle pierces the sealing element 8, and the blood is guided into the collection part through the puncture needle; the bottom of the collecting part is closed, and the collecting part can be used for collecting venous blood or supplementing peripheral blood after insufficient venous blood collection and pre-treating blood samples after blood collection.

The outer edge 11 of the blood sampling part is subjected to softening treatment of a chamfer or a fillet, the angle of the chamfer or the fillet is 30-60 degrees, and the length range of the corner edge of the chamfer or the fillet is 0.1-1 mm; the length of the blood guide tube orifice 12 is 0.5mm to 2 mm.

The collecting portion comprises an upper test tube section 3 and an inner tube 26, the upper test tube section 3 comprising a sealing area 16; the inner pipe 26 comprises an arc-shaped pipe section 4, an inner pipe body 6 and an inner pipe bottom 10; the blood collection device is further provided with an outer tube 27 located outside the inner tube 26, the outer tube 27 comprising an outer tube body 7 and an outer tube bottom 19.

The inner tube 26 is a hollow member with a closed bottom; the outer pipe 27 is a hollow piece, and the bottom of the outer pipe 27 is closed or not closed; the closed ends of the inner tube 26 and the outer tube 27 are hemispherical, parabolic or arcuate.

The length of the arc-shaped pipe section 4 is 5mm-30mm, the arc-shaped pipe section is used for connecting the outer pipe body 7 and the inner pipe body 6, and the arc-shaped pipe section 4 can prevent the probe of the instrument from deviating and colliding with the pipe wall, so that the probe is protected.

The inner pipe 26 and the outer pipe 27 are of split structures; the inner tube interface 17 is located at the joint of the arc-shaped tube section 4 and the upper test tube section 3, and the outer tube interface 18 is located at the part of the upper section of the outer tube body 7 close to the tube edge.

The inner tube 26 and the outer tube 27 are detachably connected through threads or aligned clamping grooves.

The inner tube bottom 10 and the outer tube bottom 19 are closed, and the inner bottom of the outer tube 27 restricts the movement of the inner tube by adhesion or snap-fit, thereby fixing the inner tube 26.

The contact surface of the blood sampling part is a hydrophilic contact surface.

The specifications of the blood sampling device comprise 13mm multiplied by 50mm, 13mm multiplied by 75mm and 13mm multiplied by 100mm, and the vacuum blood sampling amount of the collection part ranges from 0.1ml to 2.5 ml.

Outer tube 27 is transparent material, outer tube 27's surface sets up window 5, window 5 is geometry's breach, and the breach shape can be selected for rectangular shape or circular or oval etc. the length of window 5 is at 3mm to 60mm for the visual observation of the collection blood including the blood sampling scale.

The material of the tube body of the blood collection tube 2 is selected from one of cycloolefin copolymer (COC), polyethylene terephthalate (PET), Polyethylene (PE), Polycarbonate (PC) and polypropylene (PP) plastic materials.

The additive 9 is added into the blood collection tube 2, the additive is uniformly distributed on the inner wall of the device, the additive 9 is an anticoagulant or a coagulant, the anticoagulant comprises EDTA salt, heparin salt, citrate, double oxalate and the like, and the coagulant comprises silicon dioxide, thrombin and the like.

The tube wall thickness of the inner tube 26 and the outer tube 27 of the blood collection tube 2 is 0.6mm to 1.2mm, the diameter of the inner tube body 6 is 5mm to 10mm, the diameter of the inner tube of the blood collection tube 2 is reduced, the liquid level height of blood can be effectively improved, and the liquid level height of enough blood is improved to be 10mm to 30 mm. Outer body 7 size and the conventional blood sampling test tube of heparin tube 2 are unanimous, outer body 7 can match current instrument anchor clamps, and outer tube 27 is smooth transparent material, can match automatic subsides mark system.