阅读说明：本技术 一种化学发光分析仪及其反应装置、磁力摇匀装置 (Chemiluminescence analyzer and reaction device thereof, and magnetic shaking device ) 是由 范文彬 于 2019-11-05 设计创作，主要内容包括：本申请涉及一种用于化学发光分析仪反应装置的磁力摇匀装置,包括一组电磁线圈及其对应的控制电路,所述电磁线圈均匀设置于化学发光分析仪反应装置中各反应杯的周边,所述控制电路连接在对应电磁线圈的两端,用于控制对应的电磁线圈改变电流方向。本发明通过改变电磁线圈的电流方向,使反应物混合更加均匀,同时避免了混合液溅到杯壁,测试结果更加准确、可靠。(The application relates to a magnetic force shakes even device for chemiluminescence analysis appearance reaction unit, including a set of solenoid and the control circuit who corresponds, solenoid evenly sets up the periphery in each reaction cup in chemiluminescence analysis appearance reaction unit, control circuit connects the both ends at corresponding solenoid for the solenoid that the control corresponds changes the current direction. According to the invention, by changing the current direction of the electromagnetic coil, the reactants are mixed more uniformly, the mixed liquid is prevented from splashing on the cup wall, and the test result is more accurate and reliable.)

1. A magnetic shaking device for a reaction device of a chemiluminescence analyzer is characterized by comprising a group of electromagnetic coils and a control circuit for controlling the on-off of each electromagnetic coil, wherein the group of electromagnetic coils are respectively arranged on two sides of each reaction cup in the reaction device of the chemiluminescence analyzer;

the control circuit comprises a microcontroller and switch circuits connected in series in the energizing loops of the electromagnetic coils, and the microcontroller is used for controlling the alternate on-off of the switch circuits corresponding to the electromagnetic coils on the two sides of the reaction cup.

2. The magnetic shaking apparatus for a chemiluminescent analyzer reaction unit of claim 1 wherein the center of each electromagnetic coil is directly opposite to the nanoscale magnetic particle accumulation zone in the reaction cup.

3. The magnetic shaking-up device for the reaction device of the chemiluminescence analyzer according to claim 1, wherein the switch circuit comprises an optical coupler and an MOS circuit, the MOS circuit comprises an MOS tube, the electrical signal output end of the optical coupler is connected with the control end of the MOS tube, and the electrical input end of the optical coupler is connected with the signal output end of the microcontroller.

4. The magnetic shaking apparatus for a chemiluminescence analyzer reaction apparatus according to claim 3, wherein one switch port of the MOS tube is grounded, and the other switch port is connected with the electromagnetic coil; the optocoupler comprises a light emitting diode, the anode of the light emitting diode is connected with the anode of the power supply, and the cathode of the light emitting diode is connected with the signal output end of the microcontroller.

5. The magnetic shaking apparatus for a chemiluminescent analyzer reaction unit according to claim 3 wherein the optical coupler comprises a light emitting diode, the anode of the light emitting diode is connected to the signal output terminal of the microcontroller and the cathode of the light emitting diode is grounded.

6. The magnetic shaking apparatus for a chemiluminescent analyzer reaction unit according to any one of claims 1 to 5 further comprising a heat sink for cooling the chemiluminescent analyzer reaction unit.

7. A chemiluminescent analyzer reaction device comprising the magnetic shaking device of claim 6.

8. A chemiluminescent analyzer comprising the reaction device of claim 7.

Technical Field

The application belongs to the technical field of medical instruments, and particularly relates to a chemiluminescence analyzer and a reaction device and a magnetic shaking device thereof.

Background

The diagnosis method, in vitro diagnosis, which is the most commonly used method in the medical field at present, refers to collecting body fluid, excrement and secretion of a human body to perform chemical composition or chemical reaction analysis so as to judge human body pathological changes. Such as chemiluminescence analysis and molecular diagnosis. The diagnosis methods adopt automatic or semi-automatic instruments to sample and analyze, and give a diagnosis report.

The reaction stage of chemiluminescence immunoassay is an important stage, and whether reagents, magnetic beads and samples react sufficiently or not determines whether the value measured by the instrument can correctly reflect the current state of a patient or not. In the reaction stage, the method mainly used in the current stage is mechanical mixing, the cup-connected reaction cups are moved back and forth by the reaction device and are mixed uniformly, the single-hole reaction cup is shaken by the motor and is mixed uniformly, and the mechanical mixing has the risk of splashing the mixed liquid onto the cup wall to cause inaccurate results.

Disclosure of Invention

The technical problem to be solved by the invention is as follows: in order to solve the problem that the mixed liquid is easy to splash to the cup wall when the mixed liquid in the reaction cup is shaken up in the prior art, so that the detection and analysis results are inaccurate, the chemiluminescence analyzer, the reaction device thereof and the magnetic shaking up device are provided.

The technical scheme adopted by the invention for solving the technical problems is as follows:

the invention provides a magnetic shaking device for a reaction device of a chemiluminescence analyzer, which comprises a group of electromagnetic coils and a control circuit for controlling the on-off of each electromagnetic coil, wherein the group of electromagnetic coils are respectively arranged at two sides of each reaction cup in the reaction device of the chemiluminescence analyzer;

the control circuit comprises a microcontroller and switch circuits connected in series in the energizing loops of the electromagnetic coils, and the microcontroller is used for controlling the alternate on-off of the switch circuits corresponding to the electromagnetic coils on the two sides of the reaction cup.

Further, according to the magnetic shaking device provided by the first aspect of the present invention, the central position of each electromagnetic coil faces the nanometer-scale magnetic particle gathering area in the reaction cup.

As a possible implementation, in the magnetic shaking-up device provided in the first aspect of the present invention, the switch circuit includes an optical coupler and an MOS circuit, the MOS circuit includes an MOS transistor, an electrical signal output end of the optical coupler is connected to a control end of the MOS transistor, and an electrical input end of the optical coupler is connected to a signal output end of the microcontroller.

Further, as a possible embodiment, the magnetic shaking apparatus provided by the first aspect of the present invention, one switch port of the MOS transistor is connected to ground, and the other switch port is connected to the electromagnetic coil; the optocoupler comprises a light emitting diode, the anode of the light emitting diode is connected with the anode of the power supply, and the cathode of the light emitting diode is connected with the signal output end of the microcontroller.

In another possible embodiment, the magnetic shaking apparatus provided by the first aspect of the present invention, the optical coupler includes a light emitting diode, an anode of the light emitting diode is connected to the signal output terminal of the microcontroller, and a cathode of the light emitting diode is connected to ground.

Furthermore, the magnetic shaking device provided by the first aspect of the invention further comprises a heat dissipation device, wherein the heat dissipation device is used for cooling the reaction device for the chemiluminescence analyzer.

The invention provides a reaction device of a chemiluminescence analyzer, which comprises the magnetic shaking-up device.

In a third aspect, the present invention provides a chemiluminescent analyzer comprising the reaction apparatus described above.

The invention has the beneficial effects that: electromagnetic coils are symmetrically arranged on two sides of each reaction cup on the reaction device in an electromagnetic generating mode, and in a reagent reaction stage, the electromagnetic coils on two sides of the reaction cups are alternately controlled by a microcontroller to be electrified, so that magnetic beads continuously run in the reaction cups, reactants are fully reacted by continuous motion of the magnetic beads, the mixing is uniform, the test and analysis results are more reliable, and meanwhile, the mixed liquid is prevented from splashing on the cup walls.

Drawings

The technical solution of the present application is further explained below with reference to the drawings and the embodiments.

FIG. 1 is a schematic structural diagram of an embodiment of the present application;

FIG. 2 is a schematic diagram of a control circuit of an embodiment of the present application;

fig. 3 is a schematic diagram of a control circuit according to another embodiment of the present application.

In the figure, 1 is an electromagnetic coil, 2 is a reaction cup, and 3 is a nano-scale magnetic particle gathering area in the reaction cup

Detailed Description

It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict.

The technical solutions of the present application will be described in detail below with reference to the accompanying drawings in conjunction with embodiments.

The electromagnetic coils are symmetrically arranged on two sides of each reaction cup on the reaction device in an electromagnetic generating mode, and the electromagnetic coils on two sides of the reaction cups are alternately controlled by the microcontroller to be electrified in a reagent reaction stage, so that the nano-scale magnetic particles continuously run in the reaction cups, and reactants are fully reacted.