阅读说明：本技术 一种有助于生发的发际线填充组合物 (Hairline filling composition helpful for hair growth ) 是由 童婧 王辰啸 于 2019-11-18 设计创作，主要内容包括：本发明提供一种有助于生发的发际线填充组合物,包括以下按重量百分比计的原料：1％～5％的米诺地尔、45％～98％粉质原料或油性原料或二者混合物、0.1％～40％通透促进剂、0.1％～10％功能添加剂。本发明能够针对少发、脱发区域进行针对性治疗和修饰,从而促进毛发生长,在使用上非常方便和便携。(The invention provides a hairline filling composition helpful for hair growth, which comprises the following raw materials in percentage by weight: 1 to 5 percent of minoxidil, 45 to 98 percent of powdery raw material or oily raw material or a mixture of the powdery raw material and the oily raw material, 0.1 to 40 percent of permeation enhancer and 0.1 to 10 percent of functional additive. The invention can perform targeted treatment and modification on the hair loss area, thereby promoting the hair growth, and is very convenient and portable in use.)

1. A hairline filling composition for helping hair growth is characterized by comprising the following raw materials in percentage by weight: 1 to 5 percent of minoxidil, 45 to 98 percent of powdery raw material or oily raw material or a mixture of the powdery raw material and the oily raw material, 0.1 to 40 percent of permeation enhancer and 0.1 to 10 percent of functional additive.

2. The hairline filling composition helping hair growth according to claim 1, characterized in that: the hairline filling composition also comprises 0.1-0.5% of essence, 0.5-15% of pigment and 0.02-1% of preservative.

3. The hairline filling composition helping hair growth according to claim 1, characterized in that: the powdery raw material is any one or a mixture of any two or more of talcum powder, kaolin, zinc white powder, titanium dioxide, bentonite, calcium carbonate, calcium bicarbonate, mica, zinc stearate, magnesium stearate and polyethylene powder.

4. The hairline filling composition helping hair growth according to claim 1, characterized in that: the oily raw material is any one or a mixture of any two or more of grease, wax, higher fatty acid, alcohol and ester.

5. The hairline filling composition helping hair growth according to claim 1, characterized in that: the permeation enhancer is any one of or a mixture of any two or more of sulfoxides, pyrrolidones, azones and analogues thereof, soft permeation enhancers, terpenes, amines, amides, cyclodextrins, amino acids and esters thereof, macrocyclic compounds, phospholipids and water.

6. The hairline filling composition helping hair growth according to claim 1, characterized in that: the functional additive comprises one or more additives with effects of promoting microcirculation, metabolism, diminishing inflammation and sterilizing, such as adhesive, lactic acid, sodium lactate, PCA-Na, hyaluronic acid, hydrolyzed collagen, chitin and its derivatives, plant humectant, vitamin E, vitamin D, bioactive polypeptide and human epidermal growth factor.

Technical Field

The invention relates to the field of cosmetics, in particular to a hairline filling composition for promoting hair growth.

Background

Minoxidil is currently the only recognized drug that can be used to treat hair loss. It was first applied to hypertension, is a potassium channel agonist, and can relax vascular smooth muscle, dilate arterioles, decrease peripheral resistance, and thus lower blood pressure. Minoxidil is found to make hair (beard) longer and thicker in the treatment of hypertension. Therefore, the compound is developed and applied as a medicine for treating male pattern baldness. The exact mechanism by which it promotes hair growth is not known and may be by way of enhancing skin blood flow, affecting keratinocyte growth, and the like. The minoxidil preparation on the market is mainly liniment or gel, needs to be used every day, needs 3 months for use, and has the possibility of relapse after stopping the use.

The first generation solvent of the minoxidil hair-growing liquid is mainly ethanol and propylene glycol, the two solvents can dissolve active ingredients minoxidil and have the effect of promoting transdermal drug delivery efficiency, the product contains ethanol and propylene glycol with large dose, part of patients are stimulated to have allergic manifestations such as dandruff, scalp itch, redness and the like, and the second generation solvent of the minoxidil hair-growing liquid is improved to be a non-propylene glycol solvent, so that the side effect of propylene glycol allergy is avoided. But is easy to flow to the non-affected parts such as the hairless forehead when in use. Moreover, the hair restorer needs to be additionally used in daily life and is easy to forget.

The minoxidil-containing cosmetic is mainly shampoo, is inconvenient to use every day, has long hair washing dry time and limited use scene, cannot be used in a targeted manner, and is easy to act on the face and neck where vigorous hair is not expected.

Disclosure of Invention

Aiming at the defects of the prior art, the hairline filling composition beneficial to hair growth is provided, and can be applied by powder or paste, so that the medicine can be accurately quantified, positioned and uniformly administered, and the poor effect or side effect caused by waste and uneven application is avoided. And the effect of modifying the hair loss and hair loss area is achieved by smearing and using the medicine, the compliance of patients and the safety of medicine application are improved, and the treatment effect is realized.

The technical scheme provided by the invention is as follows: a hairline filling composition for promoting hair growth comprises the following raw materials in percentage by weight: 1 to 5 percent of minoxidil, 45 to 98 percent of powdery raw material or oily raw material or a mixture of the powdery raw material and the oily raw material, 0.1 to 40 percent of permeation enhancer and 0.1 to 10 percent of functional additive.

Furthermore, the hairline filling composition also comprises 0.1-0.5% of essence, 0.5-15% of pigment and 0.02-1% of preservative.

Further, the powdery raw material is any one of inorganic powdery raw materials such as talcum powder, kaolin, zinc white powder, titanium dioxide, bentonite, calcium carbonate and calcium bicarbonate, or organic powdery raw materials such as zinc stearate, magnesium stearate and polyethylene powder, or a mixture of any two or more of the inorganic powdery raw materials and the organic powdery raw materials.

Further, the oily raw material is any one of grease, wax, higher fatty acid, alcohol and ester or a mixture of any two or more of the grease, the wax, the higher fatty acid, the alcohol and the ester.

Further, the permeation enhancer is any one of or a mixture of any two or more of sulfoxides, pyrrolidones, Azone (laurocapram) and analogues thereof, soft permeation enhancers, fatty acids and esters thereof, surfactants, terpenes, amines, amides, cyclodextrins, amino acids, macrocyclic compounds, phospholipids and water.

Further, the functional additive includes a glue; one or more additives with microcirculation promoting, metabolism promoting, antiinflammatory, and antibacterial effects are selected from lactic acid, sodium lactate, PCA-Na, hyaluronic acid, hydrolyzed collagen, chitin and its derivatives, plant humectant, vitamin E, vitamin D, bioactive polypeptide, and human epidermal growth factor.

The hairline line filling composition has the beneficial effects that the hairline filling composition contains the minoxidil component, 1) a hair loss patient can play a role in treating hair loss during daily hairline modification, the condition that the existing minoxidil solution prepared on the basis of ethanol has large stimulation on the use of the hair loss patient is avoided, and the hairline filling composition is suitable for people allergic to the ethanol; 2) the situation that the application interval is long, the single use is matched with long hair washing time and the targeted application characteristics are lacked when the minoxidil is used for washing and protecting hair in daily use, and the minoxidil-containing hair conditioner is suitable for people who want to be operated simply and conveniently, consumes short time and strengthens the use of targeted hair loss areas; 3) the hairline-filling composition is suitable for daily use; 4) the targeted therapy can be performed on the area with few hairs and alopecia, so that the hair growth is promoted; 5) is very convenient and portable in use. The effect of promoting hair growth can be achieved when the alopecia area is locally modified by a patient, so that the invention provides great convenience for the alopecia patient, and 6) the functional additive is added, so that the hair-growing liquid has the effects of moisturizing, promoting microcirculation, promoting metabolism, diminishing inflammation and sterilizing.

Detailed Description

The present invention will be further described with reference to the following specific examples.

In the following description of the examples, the powdery raw material is any one of inorganic powdery raw materials such as talc, kaolin, zinc white, titanium dioxide, bentonite, mica, calcium carbonate, and calcium bicarbonate, or organic powdery raw materials such as zinc stearate, magnesium stearate, and polyethylene powder, or a mixture of any two or more of them.

The oily raw material is any one or mixture of two or more of oil, wax, higher fatty acid, alcohol and ester.

The permeation enhancer is any one of or a mixture of any two or more of sulfoxides, pyrrolidones, Azone and analogues thereof, soft permeation enhancers, fatty acids and esters thereof, surfactants, terpenes, amines, amides, cyclodextrins, amino acids, macrocyclic compounds, phospholipids and water.

The functional additive is a glue; one or more additives with microcirculation promoting, metabolism promoting, antiinflammatory, and antibacterial effects are selected from lactic acid, sodium lactate, PCA-Na, hyaluronic acid, hydrolyzed collagen, chitin and its derivatives, plant humectant, vitamin E, vitamin D, bioactive polypeptide, and human epidermal growth factor.