阅读说明：本技术 一种杀灭红火蚁的药剂及其制备方法 (Medicament for killing solenopsis invicta and preparation method thereof ) 是由 宋继文 胡龙祥 宋继斌 刘子 于 2019-11-26 设计创作，主要内容包括：本发明涉及一种杀灭红火蚁的药剂及其制备方法,药剂按重量份包括以下组分：氟虫腈0.13-0.24份,茚虫威/壳聚糖缓释微球2.5-5.5份,防腐剂0.3-0.8份,粘接剂1.5-3.5份,引诱剂30-40份,载体65-85份；所述茚虫威/壳聚糖缓释微球表面包覆有一层可降解膜；所述载体为小麦粉、芝麻粉或玉米粉中的一种或两种以上组合物。药剂的制备方法具体包括以下步骤：S1.将载体与水混合搅拌成乳液状,再将活性成分添加至载体乳液中搅拌均匀,之后加入茚虫威/壳聚糖缓释微球搅拌均匀,制成混合乳液；S2.向混合乳液中依次添加粘接剂、引诱剂以及防腐剂,并搅拌均匀,制成药剂初成品；S3.对药剂初成品进行挤出造粒、冷却、筛分处理,制成药剂成品。本发明具有提高药剂杀蚁持久性的效果。(The invention relates to a medicament for killing solenopsis invicta and a preparation method thereof, wherein the medicament comprises the following components in parts by weight: 0.13-0.24 part of fipronil, 2.5-5.5 parts of indoxacarb/chitosan slow-release microspheres, 0.3-0.8 part of preservative, 1.5-3.5 parts of adhesive, 30-40 parts of attractant and 65-85 parts of carrier; the surfaces of the indoxacarb/chitosan sustained-release microspheres are coated with a layer of degradable film; the carrier is one or more of wheat flour, sesame powder or corn flour. The preparation method of the medicament specifically comprises the following steps: s1, mixing and stirring a carrier and water into emulsion, adding an active ingredient into the carrier emulsion, uniformly stirring, adding indoxacarb/chitosan slow-release microspheres, and uniformly stirring to prepare mixed emulsion; s2, sequentially adding the adhesive, the attractant and the preservative into the mixed emulsion, and uniformly stirring to prepare a primary medicament finished product; and S3, carrying out extrusion granulation, cooling and screening treatment on the primary medicament finished product to prepare a finished medicament product. The invention has the effect of improving the durability of killing ants by the pesticide.)

1. The medicament for killing the solenopsis invicta comprises the following components in parts by weight:

fipronil 0.13-0.24 weight portion

2.5-5.5 parts of indoxacarb/chitosan sustained-release microspheres

0.3 to 0.8 portion of preservative

1.5 to 3.5 portions of adhesive

30-40 parts of attractant

65-85 parts of a carrier;

the surfaces of the indoxacarb/chitosan sustained-release microspheres are coated with a layer of degradable film;

the carrier is one or more of wheat flour, sesame powder or corn flour.

2. The agent for killing solenopsis invicta according to claim 1, wherein: the degradable film is a polylactic acid film.

3. The agent for killing solenopsis invicta according to claim 2, wherein: the preparation method of the polylactic acid film comprises the following steps: adding 1% of bifenthrin clothianidin solution into the polylactic acid emulsion, uniformly stirring, adding 0.5% of acetophenone solution into the polylactic acid emulsion, uniformly stirring, and finally performing plasticizing extrusion, cooling and corona treatment to prepare the polylactic acid film.

4. The agent for killing solenopsis invicta according to claim 2, wherein: the thickness of the polylactic acid film is 750-1250 um.

5. The agent for killing solenopsis invicta according to claim 1, wherein: the preservative is sodium benzoate or potassium sorbate.

6. The agent for killing solenopsis invicta according to claim 1, wherein: the adhesive is gum arabic or sodium alginate.

7. The agent for killing solenopsis invicta according to claim 1, wherein: the attractant comprises the following components in percentage by mass: (0.5-1.5): monosodium glutamate, fennel and molasses of (1-2).

8. The preparation method of the agent for killing solenopsis invicta as claimed in any one of claims 1-7, comprising the following steps:

s1, main material mixing: mixing and stirring a carrier and water into emulsion, adding the active ingredients into the carrier emulsion, uniformly stirring, adding the indoxacarb/chitosan sustained-release microspheres, and uniformly stirring, wherein the stirring temperature in the whole stirring process is 25-40 ℃, and the stirring time is 5-8min, so as to prepare mixed emulsion;

s2, addition of an auxiliary agent: sequentially adding adhesive, attractant and antiseptic into the mixed emulsion, and stirring at 25-35 deg.C for 5-10min to obtain primary product;

s3, primary product post-treatment: and (4) carrying out extrusion granulation, cooling and screening treatment on the primary medicament finished product to prepare a medicament finished product.

Technical Field

The invention relates to the technical field of pesticides, in particular to a medicament for killing solenopsis invicta and a preparation method thereof.

Background

The red imported fire ant is one of ants, belongs to social insects, and has multiple grades, including female ants, male ants and worker ants with reproductive capacity. The red fire ants belong to hymenoptera formicoidae insects, the bodies of the red fire ants are brownish red, the body types of the red fire ants are larger than those of common ants, and the adult bodies of the red fire ants are 3-6 mm long. The latin name of red imported fire ant means "invincible" ant, so that it is known to be difficult to control. The red imported fire ants are widely distributed and are one of the invasive organisms with extremely destructive power. The solenopsis invicta has strong adaptability, poor feeding property and strong fecundity and aggressiveness, and can cause disasters in a short period when newly introduced into an area. The harm caused by the red imported fire ants is mainly as follows: firstly, the safety of agricultural production is endangered, and the red imported fire ants eat seeds, fruits, buds and root systems of crops to destroy the normal growth of plants, so that the crops are seriously reduced in yield and even are completely harvested; secondly, the red fire ants bite people and animals, and people and animals are often hurt by the red fire ants, so that the people feel as painful as fire burns after being bitten by the red fire ants, then blisters appear, and a few allergic people can generate anaphylactic shock and even die; and thirdly, public facilities are damaged, and ant nests are usually built in electrical equipment and other equipment by the red fire ants, so that short circuit of electric wires or facility faults are caused. Therefore, the control of solenopsis invicta has been a major issue of international attention.

At present, chemical agents are mainly adopted at home and abroad for preventing and treating the solenopsis invicta, the existing chemical agents are mainly prepared from insecticidal components, attractants, baits, preservatives and the like, the effect of preventing and treating the solenopsis invicta is better, but obvious defects exist: the long-term action of the chemical agent on the solenopsis invicta can cause the solenopsis invicta to generate drug resistance, and once the solenopsis invicta generates the drug resistance, the insecticidal effect of the insecticidal agent is greatly reduced, so that the insecticidal agent can not continuously act on the solenopsis invicta and can not keep good drug effect for a long time.

Disclosure of Invention

Aiming at the defects in the prior art, the invention aims to provide a medicament for killing solenopsis invicta, which has the effect of improving the durability of the medicament for killing the solenopsis invicta.

The invention also aims to provide a preparation method of the medicament for killing the solenopsis invicta.

The above object of the present invention is achieved by the following technical solutions: a medicinal preparation for killing Formica rufa,

comprises the following components in parts by weight:

fipronil 0.13-0.24 weight portion

2.5-5.5 parts of indoxacarb/chitosan sustained-release microspheres

0.3 to 0.8 portion of preservative

1.5 to 3.5 portions of adhesive

30-40 parts of attractant

65-85 parts of a carrier;

the surfaces of the indoxacarb/chitosan sustained-release microspheres are coated with a layer of degradable film;

the carrier is one or more of wheat flour, sesame powder or corn flour.

By adopting the technical scheme, after the fipronil is acted on the solenopsis invicta for a long time to enable the solenopsis invicta to gradually generate drug resistance, the indoxacarb component released from the indoxacarb/chitosan slow-release microspheres continuously plays a role in killing the solenopsis invicta, so that the lasting termite killing performance of the medicament is improved;

the degradable membrane coated on the surface of the indoxacarb/chitosan slow-release microspheres is used for delaying the slow release time of indoxacarb, and after the degradable membrane is degraded, the indoxacarb in the indoxacarb/chitosan slow-release microspheres begins to release, so that the phenomenon that the indoxacarb releases and fipronil jointly acts on solenopsis invicta to cause the loss of time interval between the indoxacarb and the solenopsis invicta just after the medicament is put into use is avoided, the precedence of the termite killing effect of the fipronil and the indoxacarb is ensured, and the lasting termite killing performance of the medicament is prolonged.

The present invention in a preferred example may be further configured to: the degradable film is a polylactic acid film.

By adopting the technical scheme, the polylactic acid film is insoluble in water, so that the stability of the polylactic acid film in rainy and snowy weather is ensured;

the polylactic acid film has good biocompatibility, so that the compounding difficulty with the indoxacarb/chitosan sustained-release microspheres is reduced; the polylactic acid film has higher degradation speed, thereby avoiding that the indoxacarb can not replace fipronil immediately to continuously kill the solenopsis invicta after the pesticide effect of the fipronil is reduced.

The present invention in a preferred example may be further configured to: the preparation method of the polylactic acid film comprises the following steps: adding 1% of bifenthrin clothianidin solution into the polylactic acid emulsion, uniformly stirring, adding 0.5% of acetophenone solution into the polylactic acid emulsion, uniformly stirring, and finally performing plasticizing extrusion, cooling and corona treatment to prepare the polylactic acid film.

By adopting the technical scheme, the bifenthrin clothianidin is an active ingredient with a good ant killing effect, and is added into the polylactic acid emulsion, so that the bifenthrin clothianidin has an effect of assisting fipronil in killing ants on one hand; on the other hand, when the pesticide is just put into use, if the red fire ants gnaw the polylactic acid film, the bifenthrin clothianidin kills the red fire ants, so that the red fire ants have memory, the possibility of gnawing the polylactic acid film at the later stage is reduced, the red fire ants are prevented from gnawing the polylactic acid film to break, and the indoxacarb is prevented from being released in advance.

The present invention in a preferred example may be further configured to: the thickness of the polylactic acid film is 750-1250 um.

By adopting the technical scheme, the thickness of the polylactic acid film is controlled within a certain range, so that the degradation time of the polylactic acid film is controlled, the release time of the indoxacarb is adjusted, and the lasting termite killing performance of the pesticide is ensured.

The present invention in a preferred example may be further configured to: the preservative is sodium benzoate or potassium sorbate.

By adopting the technical scheme, the sodium benzoate has strong antibacterial power and low price; the potassium sorbate has strong antibacterial power and low toxicity, so one of the two is selected as the preservative.

The present invention in a preferred example may be further configured to: the adhesive is gum arabic or sodium alginate.

By adopting the technical scheme, the gum arabic and the sodium alginate are both plant-shaped adhesives, and the gum arabic and the sodium alginate have good gluing effect and certain food calling property, so that one of the gum arabic and the sodium alginate is selected as an adhesive for use.

The present invention in a preferred example may be further configured to: the attractant comprises the following components in percentage by mass: (0.5-1.5): monosodium glutamate, fennel and molasses of (1-2).

By adopting the technical scheme, the monosodium glutamate is delicious in taste, rich in taste level and good in food calling effect; the fragrance emitted by the fennel has the function of attracting the solenopsis invicta to seek food; the molasses has sweet taste and has the function of improving the appetite of the solenopsis invicta;

the addition amount of the three is controlled within a proper range to improve the taste of the attractant, so that the attraction effect of the attractant on the solenopsis invicta is improved.

The second purpose of the invention is realized by the following technical scheme: a preparation method of a medicament for killing solenopsis invicta comprises the following steps:

s1, main material mixing: mixing and stirring a carrier and water into an emulsion, adding fipronil into the carrier emulsion, uniformly stirring, adding indoxacarb/chitosan slow-release microspheres, uniformly stirring, wherein the stirring temperature in the whole stirring process is 25-40 ℃, and the stirring time is 5-8min, so as to prepare a mixed emulsion;

s2, addition of an auxiliary agent: sequentially adding adhesive, attractant and antiseptic into the mixed emulsion, and stirring at 25-35 deg.C for 5-10min to obtain primary product;

s3, primary product post-treatment: and (4) carrying out extrusion granulation, cooling and screening treatment on the primary medicament finished product to prepare a medicament finished product.

In summary, the invention includes at least one of the following beneficial technical effects:

1. the indoxacarb and the fipronil released from the indoxacarb/chitosan sustained-release microspheres are two active ingredients for killing ants, after the solenopsis invicta has drug resistance to the fipronil, the indoxacarb continuously plays a role in killing the solenopsis invicta after the fipronil, so that the lasting termite killing performance of the medicament is improved;

2. the degradable membrane is used for delaying the release time of the indoxacarb/chitosan slow-release microsphere indoxacarb, so that the indoxacarb can play a role in killing ants after the fipronil;

3. the bifenthrin clothianidin is added into the polylactic acid emulsion, so that the bifenthrin clothianidin has the effect of assisting fipronil in killing ants on one hand; on the other hand, the red fire ants are prevented from eating the polylactic acid film to break, so that the indoxacarb is prevented from being released in advance;

4. the thickness of the polylactic acid film is controlled within a certain range, so that the degradation time of the polylactic acid film is controlled, the release time of the indoxacarb is adjusted, and the lasting termite killing performance of the pesticide is ensured.

Drawings

Fig. 1 is a flow chart of the production process in this example.

Detailed Description

The present invention will be described in further detail with reference to the accompanying drawings.