阅读说明：本技术 采用改进的数据处理技术对组织异常进行体素内不相干运动mri三维定量检测 (Three-dimensional quantitative detection of intra-voxel incoherent motion MRI of tissue abnormalities using improved data processing techniques ) 是由 王毅翔 陈蔚天 李瑶 邓敏 梁志信 于 2018-05-15 设计创作，主要内容包括：使用体素内不相干运动(IVIM)MRI技术可以检测肝纤维化。例如,可以使用弥散加权MRI成像序列对患者的肝脏进行扫描。可以将MRI扫描中获得的信号强度数据拟合为双指数模型信号衰减,该模型表示与灌注相关的“快速”部分及与组织中弥散相关的“慢速”部分的组合。这允许提取表示慢速和快速弥散速率的参数,以及快速和慢速部分的分数贡献。在多维空间(例如,三维空间)中对这些参数的组合进行分析产生了可以区分健康肝脏和纤维化肝脏的度量。(Liver fibrosis can be detected using the intra-voxel incoherent motion (IVIM) MRI technique. For example, a diffusion weighted MRI imaging sequence may be used to scan the patient's liver. The signal intensity data obtained in an MRI scan may be fitted to a bi-exponential model of the signal attenuation, which model represents a combination of a "fast" part related to perfusion and a "slow" part related to diffusion in the tissue. This allows extraction of parameters representing slow and fast diffusion rates, as well as fractional contributions of fast and slow parts. Analysis of the combination of these parameters in a multidimensional space (e.g., a three-dimensional space) yields a metric that can distinguish between healthy and fibrotic livers.)