阅读说明：本技术 用于诊断和治疗的系统和方法 (System and method for diagnosis and treatment ) 是由 J·N·斯塔尔 S·博思 王理 于 2017-12-13 设计创作，主要内容包括：用于在医疗过程中确定病床形变量的方法。所述方法可以包括确定病床在参考点处的第一形变量,所述第一形变量对应于所述病床的第一工作位置。所述方法还可以包括确定所述病床在所述参考点处的第二形变量,所述第二形变量对应于所述病床的第二工作位置。所述方法还可以包括确定所述第一形变量和所述第二形变量之间的差值；根据所述第一形变量和所述第二形变量之间的差值,调整所述病床的所述第一工作位置和所述第二工作位置中的一个。(A method for determining the amount of bed deformation during a medical procedure. The method may include determining a first amount of deformation of a patient's bed at a reference point, the first amount of deformation corresponding to a first operating position of the patient's bed. The method may further include determining a second shape variable of the patient's bed at the reference point, the second shape variable corresponding to a second operating position of the patient's bed. The method may further comprise determining a difference between the first and second deformation quantities; adjusting one of the first and second working positions of the patient bed according to a difference between the first and second deformation amounts.)

1. A method performed at a computing device having at least one processor, at least one computer-readable storage medium, and a communication port connected to a medical device including a patient bed, the method comprising:

determining a first amount of deformation of a patient's bed at a reference point, the first amount of deformation corresponding to a first operating position of the patient's bed;

determining a second shape variable of the patient's bed at the reference point, the second shape variable corresponding to a second operating position of the patient's bed;

determining a difference between the first and second deformation quantities; and

adjusting one of the first and second working positions of the patient bed according to a difference between the first and second deformation amounts.

2. The method of claim 1, wherein the first operative position of the patient bed is associated with an imaging position and the second operative position of the patient bed is associated with a treatment position.

3. The method of claim 1, wherein the determining the first amount of deformation of the patient bed at the reference point comprises:

obtaining a first radiation image acquired by an imaging device, the first radiation image including the reference point, the reference point aligned with an isocenter of the imaging device; and

determining the first amount of deformation of the patient's bed in a first operative position from the first radiation image acquired by the imaging device.

4. The method of claim 3, wherein determining the first amount of deformation of the patient bed in the first operative position from the first radiation image acquired by the imaging device, further comprises:

determining first coordinates of the reference point in the first radiation image, the first coordinates of the reference point corresponding to the first amount of deformation of the patient bed at the reference point;

determining second coordinates of the reference point in the first radiation image, the second coordinates corresponding to an ideal state in which the patient bed is not deformed; and

and determining the first deformation amount of the sickbed in the first working position according to the first coordinate and the second coordinate.

5. The method of claim 1, wherein the determining the first amount of deformation of the patient bed at the reference point comprises:

determining a first distance of a reference point of the patient bed to the at least one first measuring device in the first working position by using the at least one first measuring device, the reference point being aligned with an isocenter of an imaging device; and

determining a first amount of deformation of the patient bed in the first operative position based on the first distance.

6. The method of claim 5, wherein the first measurement device comprises at least one of an optical detection device, a range finder, or an electromagnetic induction device.

7. The method of claim 5, wherein the determining the second shape variable of the patient's bed at the reference point comprises:

determining a second distance of a reference point of the patient's bed to the at least one first measuring device in the second working position by using the at least one first measuring device, the reference point being aligned with an isocenter of a treatment device;

and determining a second shape variable of the patient bed in the second working position according to the second distance.

8. The method of claim 1, wherein the determining the second shape variable of the patient's bed at the reference point comprises:

determining a second distance of the reference point of the patient bed to the at least one second measuring device in the second working position by using the at least one second measuring device, the reference point being aligned with the isocenter of the treatment device;

and determining the second shape variable of the sickbed in the second working position according to the second distance.

9. The method of claim 1, wherein the determining the second shape variable of the patient's bed at the reference point comprises:

obtaining a second radiation image acquired by a detector of a treatment device, wherein the detector is aligned or angled with a treatment radiation source, the second radiation image including the reference point, the reference point being aligned with an isocenter of the treatment device; and

determining the second shape variable of the patient's bed in the second operating position from a second radiation image acquired by the treatment device.

10. The method of claim 8, wherein the at least one second measurement device comprises at least one of an optical detection device, a range finder, or an electromagnetic induction device.

11. The method of claim 10, wherein the optical detection device comprises at least one charge-coupled device (CCD).

12. The method of claim 10, wherein the electromagnetic induction device comprises a magnetic induction coil, an electromagnetic transmitter (EML), and an electromagnetic receiver, the magnetic induction coil being connected to the patient bed.

13. The method of claim 10, wherein the rangefinder comprises at least one of an ultrasonic rangefinder, a laser rangefinder, or a radar rangefinder.

14. A method performed at a computing device having at least one processor, at least one computer-readable storage medium, and a communication port connected to a medical device including a patient bed, the method comprising:

determining the displacement of the patient bed between the first working position and the second working position in the first coordinate direction by using at least one measuring device;

determining the deformation quantity of the sickbed at the reference point according to the displacement quantity of the sickbed in the first coordinate direction, wherein the deformation quantity of the sickbed at the reference point corresponds to the second working position; and

and adjusting the second working position of the sickbed according to the deformation of the sickbed in the first coordinate direction.

15. The method of claim 14, wherein the at least one measurement device comprises at least one of an optical detection device, a range finder, or an electromagnetic induction device.

16. The method of claim 15, the first operative position of the patient bed being associated with an imaging position and the second operative position of the patient bed being associated with a treatment position.

17. A system for a medical device, comprising:

a Computed Tomography (CT) device located at a first location;

a Radiation Therapy (RT) device at a second location, the radiation therapy device connected to the computed tomography device, the computed tomography device and the radiation therapy device sharing a common bore;

a patient bed including a motion assembly configured to move the patient bed between the first position and the second position through the aperture; and

a range finder associated with the patient bed, the range finder configured to acquire data relating to a position of the patient bed at a reference point when in the second position,

wherein the computer tomography apparatus is configured to acquire data related to the position of the patient bed at the reference point when in the first position based on

Determining an amount of deformation of the patient's bed in the second position at the reference point relative to the patient's bed in the first position based on the data relating to the position of the patient's bed at the reference point in the second position and the data relating to the position of the patient's bed at the reference point in the first position.

18. The method of claim 17, wherein the data relating to the position of the reference point on the patient bed in the second position and the data relating to the position of the reference point on the patient bed in the first position determine an amount of deformation of the patient bed in the second position at the reference point relative to the patient bed in the first position, further comprising:

determining a first amount of deformation of the patient's bed at the reference point from data relating to the position of the reference point on the patient's bed at the first position, the first amount of deformation corresponding to the first position;

determining a second shape variable of the patient's bed at the reference point from the data relating to the location of the reference point on the patient's bed at the second location, the second shape variable corresponding to the second location; and

determining an amount of deformation of the patient's bed in the second position relative to the patient's bed in the first position at the reference point based on a difference between the first amount of deformation and the second amount of deformation.

19. A system for a medical device comprising a patient bed having a table top, the system comprising:

at least one processor; and

executable instructions, executed by the at least one processor, cause the system to implement a method comprising:

determining a first amount of deformation of a patient's bed at a reference point, the first amount of deformation corresponding to a first operating position of the patient's bed;

determining a second shape variable of the patient's bed at the reference point according to at least one first measurement device, the second shape variable corresponding to a second working position of the patient's bed;

determining a difference between the first and second deformation quantities; and

adjusting one of the first and second working positions of the patient bed according to a difference between the first and second deformation amounts.

20. A non-transitory computer-readable medium, comprising:

instructions for execution by at least one processor, the instructions causing the at least one processor to implement a method comprising:

determining a first amount of deformation of a patient's bed at a reference point, the first amount of deformation corresponding to a first operating position of the patient's bed;

determining a second shape variable of the patient's bed at the reference point according to at least one first measurement device, the second shape variable corresponding to a second working position of the patient's bed;

determining a difference between the first and second deformation quantities; and

adjusting one of the first and second working positions of the patient bed according to a difference between the first and second deformation amounts.

21. A system having at least one processor and a memory, comprising:

a data processing module configured to:

determining a first amount of deformation of a patient's bed at a reference point, the first amount of deformation corresponding to a first operating position of the patient's bed;

determining a second shape variable of the patient's bed at the reference point according to at least one first measurement device, the second shape variable corresponding to a second working position of the patient's bed;

determining a difference between the first and second deformation quantities; and

adjusting one of the first and second working positions of the patient bed according to a difference between the first and second deformation amounts.

22. A system for a medical device, the medical device including a patient bed having a tabletop, comprising:

at least one processor; and

executable instructions, executed by the at least one processor, cause the system to implement a method comprising:

determining the displacement of the patient bed between the first working position and the second working position in the first coordinate direction by using at least one measuring device;

determining the deformation amount of the sickbed at the reference point according to the displacement amount of the sickbed in the first coordinate direction, wherein the deformation amount of the sickbed at the reference point corresponds to the second working position; and

and adjusting the second working position of the sickbed according to the deformation amount of the sickbed in the first coordinate direction.

23. A non-transitory computer-readable medium, comprising:

instructions for execution by at least one processor, the instructions causing the at least one processor to implement a method comprising:

determining the displacement of the patient bed between the first working position and the second working position in the first coordinate direction by using at least one measuring device;

determining the deformation amount of the sickbed at the reference point according to the displacement amount of the sickbed in the first coordinate direction, wherein the deformation amount of the sickbed at the reference point corresponds to the second working position; and

and adjusting the second working position of the sickbed according to the deformation amount of the sickbed in the first coordinate direction.

24. A system having at least one processor and a memory, comprising:

a data processing module configured to:

determining the displacement of the patient bed between the first working position and the second working position in the first coordinate direction by using at least one measuring device;

determining the deformation amount of the sickbed at the reference point according to the displacement amount of the sickbed in the first coordinate direction, wherein the deformation amount of the sickbed at the reference point corresponds to the second working position; and

and adjusting the second working position of the sickbed according to the deformation amount of the sickbed in the first coordinate direction.

Technical Field

The present application relates generally to medical diagnostic and treatment systems, and more particularly to methods and systems for determining deformation of a patient's bed during a medical procedure.

Background

Various imaging techniques, such as X-ray imaging, Magnetic Resonance Imaging (MRI), Computed Tomography (CT), Positron Emission Tomography (PET), and the like, have been widely used in medical diagnosis, radiation therapy planning, surgical planning, and other medical procedures. Generally, a patient bed may be used for supporting and/or transferring an object to be examined to a scanning area of an imaging device and/or a treatment device. In some embodiments, a patient bed carrying an object to be examined (e.g., a patient) may deform, e.g., sag or deflect, during a medical procedure. For example, in multi-modality imaging, when a patient bed extends to a scanning area of a multi-modality imaging apparatus along a longitudinal direction of the patient bed, the patient bed may sink, resulting in poor image quality and inaccurate fused images. As another example, during image-guided radiation therapy (IGRT), the couch may sink as it is moved from the imaging device to the treatment device, resulting in inaccurate positioning of target points (e.g., anatomical points). When the bed is moved in a horizontal direction to transfer the object to be examined to the scanning area, the horizontal position of the bed can be read out from the motion control system. However, there is always a certain degree of deflection or subsidence in the vertical direction of the bed, which cannot be read from the motion control system. It is therefore desirable to provide a system and a method that are capable of correcting the deformation of a patient bed in the vertical direction to stabilize the spatial position of at least a part of the object to be examined during a medical procedure.

Disclosure of Invention

According to one aspect of the present application, a method for determining deformation of a patient bed is provided. The method may be implemented on at least one machine, each machine having at least one processor and memory. The method may include determining a first amount of deformation of a patient's bed at a reference point, the first amount of deformation corresponding to a first operating position of the patient's bed; determining a second shape variable of the patient's bed at a reference point, the second shape variable corresponding to a second operating position of the patient's bed; determining a difference between the first and second deformation quantities; and adjusting one of the first and second working positions of the patient bed according to a difference between the first and second deformation amounts.

In some embodiments, the first operative position of the patient bed may be associated with an imaging position and the second operative position of the patient bed is associated with a treatment position.

In some embodiments, the determining the first amount of deformation of the patient's bed at the reference point comprises: obtaining a first radiation image acquired by an imaging device, the first radiation image including the reference point, the reference point aligned with an isocenter of the imaging device; and determining a first amount of deformation of the patient's bed in a first operative position from the first radiation image acquired by the imaging device.

In some embodiments, determining a first amount of deformation of the patient's bed in the first operative position from the first radiation image acquired by the imaging device may further comprise: determining first coordinates of the reference point in the first radiation image, the first coordinates of the reference point corresponding to the first amount of deformation of the patient bed at the reference point; determining second coordinates of the reference point in the first radiation image, the second coordinates corresponding to an ideal state that the patient bed is not deformed; and determining the first deformation amount of the sickbed in the first working position according to the first coordinate and the second coordinate.

In some embodiments, the determining the first amount of deformation of the patient's bed at the reference point comprises: determining a first distance of a reference point of the patient bed to the at least one first measuring device in the first working position by using the at least one first measuring device, the reference point being aligned with an isocenter of an imaging device; and determining a first deformation amount of the patient bed in the first working position according to the first distance.

In some embodiments, the at least one first measurement device may comprise at least one of an optical detection device, a range finder, or an electromagnetic induction device.

In some embodiments, the determining the second shape variable of the patient's bed at the reference point may comprise: determining a second distance of a reference point of the patient's bed to the at least one first measuring device in the second working position by using the at least one first measuring device, the reference point being aligned with an isocenter of a treatment device; and determining a second shape variable of the patient bed in the second working position according to the second distance.

In some embodiments, the determining the second shape variable of the patient's bed at the reference point comprises: determining a second distance of the reference point of the patient bed to the at least one second measuring device in the second working position by using the at least one second measuring device, the reference point being aligned with the isocenter of the treatment device; and determining the second shape variable of the sickbed in the second working position according to the second distance.

In some embodiments, the determining the second shape variable of the patient's bed at the reference point may comprise obtaining a second radiation image acquired by a detector of the treatment device. The detector is aligned or angled with respect to the therapeutic radiation source. The second radiation image may include the reference point, the reference point being aligned with an isocenter of the treatment device; and determining the second shape variable of the patient's bed in the second operating position from a second radiation image acquired by the treatment device.

In some embodiments, the at least one second measurement device may comprise at least one of an optical detection device, a range finder, or an electromagnetic induction device.

In some embodiments, the optical detection device may comprise at least one Charge Coupled Device (CCD).

In some embodiments, the electromagnetic induction device may comprise a magnetic induction coil, an electromagnetic transmitter (EML) and an electromagnetic receiver, the magnetic induction coil being connected to the patient bed, or the like.

In some embodiments, the rangefinder may comprise at least one of an ultrasonic rangefinder, a laser rangefinder, or a radar rangefinder.

According to one aspect of the present application, a method for determining deformation of a patient bed is provided. The method may be implemented on at least one machine, each machine having at least one processor and memory. The method may include determining, by using at least one measurement device, an amount of displacement of the patient bed in a first coordinate direction between a first operative position of the patient bed and a second operative position of the patient bed; determining the deformation amount of the sickbed at the reference point according to the displacement amount of the sickbed in the first coordinate direction, wherein the deformation amount of the sickbed corresponds to the second working position; and adjusting the second working position of the sickbed according to the deformation of the sickbed in the first coordinate direction.

In some embodiments, the at least one measurement device may comprise at least one of an optical detection device, a range finder, or an electromagnetic induction device.

In some embodiments, the first operating position of the patient bed can be associated with an imaging position and the second operating position of the patient bed can be associated with a treatment position.

According to one aspect of the present application, a system for a medical device is provided. The system may include a Computed Tomography (CT) device located at a first location; a Radiation Therapy (RT) device at a second location, the radiation therapy device connected to the computed tomography device, the computed tomography device and the radiation therapy device sharing a common bore; a patient bed including a motion assembly configured to pass through the aperture when the patient bed is between the first position and the second position; and a rangefinder associated with the examination table, the rangefinder configured to acquire data relating to a position of the patient bed at a reference point. In some embodiments, the computer tomography apparatus may be configured to acquire data related to the position of the patient bed at the reference point at the first position. The amount of deformation of the bed at the reference point in the second position relative to the first position may be determined from the data relating to the position of the bed at the reference point in the second position and the data relating to the position of the bed at the reference point in the first position.

In some embodiments, a first amount of deformation of the patient's bed at the reference point corresponding to the first location may be determined from data relating to the position of the patient's bed at the reference point at the first location. A second shape variable of the patient's bed at the reference point corresponding to the second location may be determined from the data relating to the location of the reference point of the patient's bed at the second location. The amount of deformation of the patient's bed relative to the reference point of the second position of the first position may be determined from the difference between the first amount of deformation and the second amount of deformation.

According to one aspect of the present application, a system for determining deformation of a patient bed is provided. The system may include a computer-readable storage medium storing executable instructions and at least one processor in communication with the computer-readable storage medium. Executable instructions, when executed, may cause a system to implement a method. The method may include determining a first amount of deformation of a patient bed at a reference point, the first amount of deformation corresponding to a first operating position of the patient bed; determining a second shape variable of the patient's bed at the reference point, corresponding to a second working position of the patient's bed, according to at least one first measuring device; determining a difference between the first and second deformation quantities; and adjusting one of the first and second working positions of the patient bed according to a difference between the first and second deformation amounts.

According to another aspect of the present application, a non-transitory computer-readable medium is provided. The non-transitory computer readable medium may include executable instructions. When executed by at least one processor, the instructions may cause the at least one processor to implement a method. The method may include determining a first amount of deformation of the patient's bed at the reference point, the first amount of deformation corresponding to a first operating position of the patient's bed; determining a second shape variable of the patient's bed at the reference point, corresponding to a second working position of the patient's bed, according to at least one first measuring device; determining a difference between the first and second deformation quantities; and adjusting one of the first and second working positions of the patient bed according to a difference between the first and second deformation amounts.

According to one aspect of the present application, a system for determining deformation of a patient bed is provided. The system may include a data processing module configured to determine a first amount of deformation of the patient bed at a reference point, the first amount of deformation corresponding to a first operating position of the patient bed; determining a second shape variable of the patient's bed at the reference point, corresponding to a second working position of the patient's bed, according to at least one first measuring device; determining a difference between the first and second deformation quantities; and adjusting one of the first and second working positions of the patient bed according to a difference between the first and second deformation amounts.

According to one aspect of the present application, a system for determining deformation of a patient bed is provided. The system may include a computer-readable storage medium storing executable instructions and at least one processor in communication with the computer-readable storage medium. The executable instructions, when executed, may cause the system to implement a method. The method may include determining an amount of displacement of the patient bed in a first coordinate direction between a first operative position of the patient bed and a second operative position of the patient bed using at least one measurement device; determining the deformation amount of the sickbed at a reference point according to the displacement amount of the sickbed in the first coordinate direction, wherein the deformation amount of the sickbed corresponds to the second working position; and adjusting a second working position of the sickbed according to the deformation amount of the sickbed in the first coordinate direction.

According to another aspect of the present application, a non-transitory computer-readable medium is provided. The non-transitory computer readable medium may include executable instructions. The instructions, when executed by the at least one processor, may cause the at least one processor to implement a method. The method may include determining an amount of displacement of the patient bed in a first coordinate direction between a first operative position of the patient bed and a second operative position of the patient bed using at least one measurement device; determining the deformation amount of the sickbed at a reference point according to the displacement amount of the sickbed in the first coordinate direction, wherein the deformation amount of the sickbed corresponds to the second working position; and adjusting a second working position of the sickbed according to the deformation amount of the sickbed in the first coordinate direction.

According to one aspect of the present application, a system for determining deformation of a patient bed is provided. The system may comprise a data processing module configured to determine, by using at least one measuring device, an amount of displacement of the patient's bed in a first coordinate direction between a first operative position of the patient's bed and a second operative position of the patient's bed; determining the deformation amount of the sickbed at the reference point according to the displacement amount of the sickbed in the first coordinate direction, wherein the deformation amount of the sickbed corresponds to the second working position; and adjusting the second working position of the sickbed according to the deformation of the sickbed in the first coordinate direction.

Additional features of the present application will be set forth in part in the description which follows. Additional features of some aspects of the present application will be apparent to those of ordinary skill in the art in view of the following description and accompanying drawings, or in view of the production or operation of the embodiments. The features of the present application may be realized and attained by practice or use of the methods, instrumentalities and combinations of the various aspects of the specific embodiments described below.

Drawings

The present application will be further described in conjunction with the exemplary embodiments. These exemplary embodiments will be described in detail with reference to the accompanying drawings. These embodiments are not intended to be limiting, and like reference numerals refer to like parts throughout, wherein:

FIG. 1 is a schematic view of an exemplary diagnostic and therapeutic system shown in accordance with some embodiments of the present application;

fig. 2 is a side view of an exemplary RT-CT apparatus and related components shown in accordance with some embodiments of the present application;

FIG. 3 is a schematic diagram of exemplary hardware and/or software components of an exemplary computing device on which a processing device may be implemented in accordance with some embodiments of the present application;

FIG. 4 is a diagram illustrating exemplary hardware and/or software components of an exemplary mobile device on which a terminal may be implemented according to some embodiments of the present application;

FIG. 5 is a block diagram of an exemplary processing device shown in accordance with some embodiments of the present application;

FIG. 6 is a flow chart of an exemplary process for determining the amount of deformation of a treatment location relative to an imaging location, shown in accordance with some embodiments of the present application;

FIG. 7 is a flow chart of an exemplary process for determining the amount of deformation of a patient's bed at a treatment location relative to an imaging location, shown in accordance with some embodiments of the present application;

FIG. 8 is a flow chart of an exemplary process for determining the amount of deformation of a patient's bed at a reference point of an imaging location, shown in accordance with some embodiments of the present application;

FIG. 9 is a schematic diagram illustrating an example for determining the amount of subsidence of a treatment location relative to an imaging location according to some embodiments of the present application;

fig. 10 is a schematic diagram of an example for determining a subsidence of an example IGRT device, according to some embodiments of the present application;

fig. 11 is a schematic diagram illustrating an example for determining a subsidence of an example IGRT device, according to some embodiments of the present application; and

fig. 12 is a schematic diagram of an example for determining a subsidence of an example IGRT device, according to some embodiments of the present application.

Detailed Description

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings used in the description of the embodiments will be briefly introduced below. However, it will be apparent to one skilled in the art that the present application may be practiced without these specific details. In other instances, well known methods, procedures, systems, components, and/or circuits have been described at a high level of summary in order to avoid unnecessarily obscuring aspects of the present application. It will be apparent to those skilled in the art that various modifications to the disclosed embodiments are possible, and that the general principles defined in this application may be applied to other embodiments and applications without departing from the spirit and scope of the application. Thus, the present application is not limited to the embodiments shown, but is to be accorded the widest scope consistent with the claims.

The terminology used in the description presented herein is for the purpose of describing particular example embodiments only and is not intended to limit the scope of the present application. As used herein, the singular forms "a", "an" and "the" may include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and/or "comprising," when used in this specification, specify the presence of stated features, integers, steps, operations, components, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, components, and/or groups thereof.

It should be understood that the terms "system," "engine," "unit," "module," and/or "block" as used herein are a way of distinguishing between different components, elements, components, parts, or assemblies of different levels in ascending order. However, other expressions may be substituted for these terms if they achieve the same purpose.

Generally, the words "module," "unit," or "block" as used herein refers to logic embodied in hardware or firmware, or a collection of software instructions. The modules, units or blocks described herein may be implemented as software and/or hardware and may be stored in any type of non-transitory computer-readable medium or other storage device. In some embodiments, software modules/units/blocks may be compiled and linked into an executable program. It should be understood that software modules may be invoked from other modules/units/blocks or from themselves, and/or may be invoked in response to detected events or interrupts. The software modules/units/blocks (e.g., processor 310 as shown in fig. 3) for execution on a computing device may be provided on a computer readable medium, such as a compact disc, digital video disc, flash drive, diskette, or any other tangible medium, or digitally downloaded (and may be initially stored in a compressed or installable format, requiring installation, decompression, or decryption prior to execution). The software code herein may be stored in part or in whole in a memory device of a computing device performing the operations and employed in the operations of the computing device. The software instructions may be embedded in firmware, such as erasable programmable read-only memory (EPROM)). It should also be understood that hardware modules/units/blocks may be included in connected logic components, such as gates and flip-flops, and/or may include programmable units, such as programmable gate arrays or processors. The modules/units/blocks or computing device functions described herein may be implemented as software modules/units/blocks, but may be represented in hardware or firmware. Generally, the modules/units/blocks described herein refer to logical modules/units/blocks that may be combined with other modules/units/blocks or split into sub-modules/sub-units/sub-blocks, regardless of their physical organization or storage. The description may apply to the system, the engine, or portions thereof.

It will be understood that when a unit, engine, module or block is referred to as being "on," "connected to," or "coupled to" another unit, engine, module or block, it can be directly on, connected or coupled to or in communication with the other unit, engine, module or block, or intervening units, engines, modules or blocks may be present, unless the context clearly dictates otherwise. In this application, the term "and/or" may include any one or more of the associated listed items or combinations thereof.

These and other features, aspects, and advantages of the present application, as well as the methods of operation and functions of the related elements of structure and the combination of parts and economies of manufacture, will become more apparent upon consideration of the following description of the accompanying drawings, all of which form a part of this specification. It is to be understood, however, that the drawings are designed solely for the purposes of illustration and description and are not intended as a definition of the limits of the application. It should be understood that the drawings are not to scale.

Systems and assemblies for medical diagnosis and/or treatment are provided herein. In some embodiments, the medical system may include a diagnostic system. The diagnostic system may include a multi-modality imaging system. The multi-modality imaging system can include, for example, a computed tomography-positron emission tomography (CT-PET) system, a computed tomography-positron emission tomography-magnetic resonance imaging (CT-MRI) system, an X-ray imaging-magnetic resonance imaging (X-ray-MRI) system, a positron emission tomography-X-ray imaging (PET-X-ray) system, a single photon emission computed tomography-magnetic resonance imaging (SPECT-MRI) system, a digital subtraction angiography-magnetic resonance imaging (DSA-MRI) system, or the like, or a combination thereof. In some embodiments, the medical system may include a diagnostic and therapeutic system. The diagnosis and treatment system may include a Treatment Planning System (TPS), an Image Guided Radiation Therapy (IGRT) system, and the like. By way of example only, an Image Guided Radiation Therapy (IGRT) system may include, for example, a CT guided radiation therapy system, an MRI guided radiation therapy system, and the like.

The present application relates to systems and methods for determining the subsidence of a patient's bed during radiation therapy. In some embodiments, a first amount of deformation of the patient's bed at a reference point may be determined. The first amount of deformation of the patient's bed may correspond to an imaging position. A second shape variable of the patient's bed at the reference point may be determined. The second form of the patient's bed may correspond to the treatment location. Then, a difference between the first and second deformation amounts may be determined. The difference between the first and second deformation amounts may also be referred to as the amount of deformation of the patient's bed at the treatment position relative to the imaging position. In some embodiments, the treatment position of the patient bed may be adjusted according to a difference between the first and second deformation amounts.

It should be noted that the diagnostic and therapy system 100 described below is for illustrative purposes only and is not intended to limit the scope of the present application. Certain amounts of variations, changes and/or modifications may be deducted by persons having ordinary skill in the art in light of the present application. Such changes, variations and/or modifications may be made without departing from the scope of the present application.

Fig. 1 is a schematic diagram of an exemplary diagnostic and therapy system 100 shown in accordance with some embodiments of the present application. As shown, the diagnostic and therapy system 100 may include an image-guided radiation therapy (IGRT) device 110, a processing device 120, a memory 130, one or more terminals 140, and a network 150. In some embodiments, IGRT devices 110, processing devices 120, memory 130, and/or terminals 140 may be connected to and/or communicate with each other via a wireless connection (e.g., network 150), a wired connection, or a combination thereof. The connections between components in diagnostic and therapy system 100 may vary. For example only, as shown in fig. 1, the IGRT device 110 may be connected to the processing device 120 through a network 150. As another example, the IGRT device 110 may be directly connected to the processing device 120. As another example, as shown in FIG. 1, memory 130 may be connected to processing device 120 through network 150 or directly to processing device 120. As another example, as shown in FIG. 1, terminal 140 may be connected to processing device 120 via network 150 or directly to processing device 120.

IGRT device 110 may be a multi-modality (e.g., dual-modality) device to acquire medical images related to and deliver radiation therapy to at least a portion of a subject. The medical image may be a Computed Tomography (CT) image, a Magnetic Resonance Imaging (MRI) image, an ultrasound image, or the like, or a combination thereof. In some embodiments, the medical image may be a two-dimensional (2D) image, a three-dimensional (3D) image, a four-dimensional (4D) image, or the like, or a combination thereof. The subject may be biological or non-biological. For example, the object may include a patient, an artificial object, and the like. As another example, the object may include a particular part, organ, and/or tissue of the patient. For example, the object may include a head, neck, chest, heart, stomach, blood vessels, soft tissue, tumor, nodule, etc., or a combination thereof.

In some embodiments, IGRT device 110 may include an imaging device 112, a treatment device 114, and a patient bed 116. The imaging device 112 may provide medical images for determining at least a portion (e.g., an anatomical point) of a subject. Exemplary imaging devices may include, for example, CT devices, cone beam CT devices, PET devices, volume CT devices, MRI devices, and the like, or combinations thereof. The treatment device 114 may deliver radiation treatment to at least a portion of the subject based on the medical images and other information. An exemplary treatment device may include a linear accelerator, an X-ray treatment device, or the like, a patient bed 116 may be configured to support and/or transfer at least a portion of the subject to, for example, a scanning region of the imaging device 112 and/or the treatment device 114. For example, the patient bed 116 may be moved to transfer at least a portion of the subject from the imaging device 112 to the therapy device 114.

In some embodiments, the imaging device 112 and the therapy device 114 may be placed independently of each other. In some embodiments, the imaging device 112 may be integrated with the therapy device 114. The imaging device 112 and the therapy device 114 may share the same bore, which may be used to accommodate a subject to be imaged and/or treated. The patient bed 116 may be configured to transfer an object to be imaged and/or processed to a detection region in the bore. The patient bed 116 may include a motion assembly for moving the patient bed 116 in various directions. For example, the motion assembly may move the patient bed 116 along a longitudinal direction of the patient bed 116. For another example, the motion assembly may raise the patient bed 116 in a vertical direction. More description of at least a portion of IGRT device 110 (e.g., imaging device 112, treatment device 114, patient bed 116) may be found in U.S. application publication No. 20170189719 entitled "RADIATION THERAPY position system," U.S. application publication No. 20170189720 entitled "RADIATION THERAPY THERAPY SYSTEM," and/or U.S. application publication No. 20170189724 entitled "RADIATION THERAPY THERAPY SYSTEM," the contents of which are incorporated herein by reference. In some embodiments, IGRT device 110 may also include a measurement device (not shown). The measurement device may be used to acquire data related to the position of at least a portion of the components in the IGRT device 110, e.g., the patient bed 116 and/or to directly determine the position of at least a portion of the components in the IGRT device 110. The data relating to the location of at least a portion of the components in the IGRT device 110 may be static data including data relating to at least a portion of the components in the IGRT device 110, image data relating to at least a portion of the components in the IGRT device 110, the like, or a combination thereof. Exemplary static data related to at least a portion of the components in the IGRT device 110 may include a distance from a point on at least a portion of the components in the IGRT device 110 (e.g., the patient bed 116) to the measurement device, an orientation of a point on at least a portion of the components in the IGRT device 110 (e.g., the patient bed 116) relative to the measurement device, and the like. Exemplary imaging data relating to at least a portion of the components in the IGRT device 110 may include optical images or the like relating to at least a portion of the components in the IGRT device 110 (e.g., the patient bed 116). A more detailed description of the measuring device can be found in fig. 2.

The processing device 120 may process data and/or information obtained from the IGRT device 110, the memory 130, and/or the terminal 140. For example, the processing device 120 may reconstruct an image related to at least a portion of the object (e.g., a tumor) based on projection data acquired by the IGRT device 110 (e.g., the imaging device 112). For another example, the processing device 120 may determine a treatment plan based on at least a portion of the subject (e.g., a tumor) in the image acquired by the imaging device 112. As another example, the processing device 120 may determine a deformation amount (e.g., a dip) at a point on the patient bed based on data regarding the position of at least a portion of the components in the IGRT device 110 (e.g., patient bed 116) and/or the position of at least a portion of the components in the IGRT device 110 (e.g., patient bed 116) acquired by the measurement device.

In some embodiments, the processing device 120 may be a single server or a group of servers. The server groups may be centralized or distributed. In some embodiments, the processing device 120 may be local or remote. For example, the processing device 120 may access information and/or data from the IGRT device 110, the memory 130, and/or the terminal 140 via the network 150. As another example, the processing device 120 may be directly connected to the IGRT device 110, the terminal 140, and/or the memory 130 to access information and/or data. In some embodiments, the processing device 120 may be implemented on a cloud platform. For example, the cloud platform may include a private cloud, a public cloud, a hybrid cloud, a community cloud, a distributed cloud, an inter-cloud, a multi-cloud, and the like, or combinations thereof. In some embodiments, the processing device 120 may be implemented on a mobile device 400 having one or more components as described in connection with fig. 2.

Memory 130 may store data, instructions, and/or any other information. In some embodiments, memory 130 may store data obtained from IGRT device 110, processing device 120, and/or terminal 140. In some embodiments, memory 130 may store data and/or instructions that processing device 120 may perform or be used to perform the exemplary methods described herein. In some embodiments, memory 130 may include mass storage, removable storage, volatile read-write memory, read-only memory (ROM), and the like, or any combination thereof. Exemplary mass storage devices may include magnetic disks, optical disks, solid state disks, and the like. Exemplary removable memory may include flash drives, floppy disks, optical disks, memory cards, compact disks, magnetic tape, and the like. Exemplary volatile read and write memories can include Random Access Memory (RAM). Exemplary RAM may include Dynamic Random Access Memory (DRAM), double data rate synchronous dynamic random access memory (DDR SDRAM), Static Random Access Memory (SRAM), thyristor random access memory (T-RAM), and zero capacitance random access memory (Z-RAM), among others. Exemplary read-only memories may include mask read-only memory (MROM), programmable read-only memory (PROM), erasable programmable read-only memory (EPROM), electrically erasable programmable read-only memory (EEPROM), compact disc read-only memory (CD-ROM), digital versatile disc read-only memory (dvd-ROM), and the like. In some embodiments, memory 130 may be implemented on a cloud platform, as described elsewhere in this application.

In some embodiments, the memory 130 may be connected to the network 150 to communicate with one or more other components (e.g., the processing device 120, the terminal 140, etc.) in the diagnostic and therapy system 100. One or more components in the diagnostic and therapy system 100 may access data or instructions stored in the memory 130 via the network 150. In some embodiments, the memory 130 may be part of the processing device 120.

The terminal 140 may be connected to and/or in communication with the IGRT device 110, the processing device 120, and/or the memory 130. For example, the terminal 140 may obtain a processed image from the processing device 120. For another example, the terminal 140 may obtain image data acquired via the IGRT device 110 and send the image data to the processing device 120 for processing. In some embodiments, the terminal 140 may include a mobile device 140-1, a tablet computer 140-2, … …, a laptop computer 140-N, or the like, or any combination thereof. For example, the mobile device 140-1 may include a mobile phone, a Personal Digital Assistant (PDA), a gaming device, a navigation device, a point of sale (POS) device, a laptop computer, a tablet computer, a desktop, and the like, or any combination thereof. In some embodiments, terminal 140 may include input devices, output devices, etc. input devices may include keys capable of entering alphanumeric and other keys through a keyboard, a touch screen (e.g., with tactile or haptic feedback), voice input, eye tracking input, brain monitoring system, or any other similar input mechanism. Input information received via the input device may be sent via, for example, a bus to the processing device 120 for further processing. Other types of input devices may include cursor control devices such as a mouse, a trackball, or cursor direction keys, among others. Output devices may include a display, speakers, printer, etc., or a combination thereof. In some embodiments, the terminal 140 may be part of the processing device 120.

Network 150 may include any suitable network that may facilitate the exchange of information and/or data for diagnostic and therapy system 100. In some embodiments, one or more components of the diagnostic and therapy system 100 (e.g., IGRT device 110, processing device 120, memory 130, terminal 140, etc.) may communicate information and/or data with one or more other components of the diagnostic and therapy system 100 over the network 150. For example, the processing device 120 may obtain image data from the IGRT device 110 via the network 150. As another example, processing device 120 may obtain user instructions from terminal 140 via network 150. The network 150 may be and/or include a public network (e.g., the internet), a private network (e.g., a Local Area Network (LAN), a Wide Area Network (WAN)), etc.), a wired network (e.g., an ethernet network), a wireless network (e.g., an 802.11 network, a Wi-Fi network, etc.), a cellular network (e.g., a Long Term Evolution (LTE) network), a frame relay network, a Virtual Private Network (VPN), a satellite network, a telephone network, a router, a hub, a wizard, a server computer, and/or any combination thereof. For example, network 150 may include a wireline network, a fiber optic network, a telecommunications network, an intranet, a Wireless Local Area Network (WLAN), a Metropolitan Area Network (MAN), a Public Switched Telephone Network (PSTN), a bluetooth network, a zigbee network, a Near Field Communication (NFC) network, the like, or any combination thereof. In some embodiments, the network 150 may include one or more network access points. For example, network 150 may include wired and/or wireless network access points, such as base stations and/or internet exchange points, through which one or more components of diagnostic and therapy system 100 may connect to network 150 to exchange data and/or information.

The description is intended to be illustrative, and not to limit the scope of the application. Many alternatives, modifications, and variations will be apparent to those skilled in the art. The features, structures, methods, and other features of the exemplary embodiments described herein may be combined in various ways to obtain additional and/or alternative exemplary embodiments. For example, memory 130 may be a data store comprising a cloud computing platform, such as a public cloud, a private cloud, a community and hybrid cloud, and so forth. However, those variations and modifications do not depart from the scope of the present application.

Fig. 2 is a side view of an exemplary RT-CT device 200 and related components shown in accordance with some embodiments of the present application. The RT-CT device 200 may be the exemplary IGRT device 110 as shown in fig. 1. RT-CT device 200 may include CT device 220, RT device 240, patient bed 260, and measurement device 280.

The CT device 220 may acquire a CT image related to at least a portion of the object by scanning the at least a portion of the object. In some embodiments, the CT device 220 may include a radiation source, a detector, and the like. The radiation source, such as a bulb, may emit a beam of radiation. The detector can detect the radiation beam emitted from the radiation source and generate a signal (e.g., an electronic signal, a digital signal, etc.). The CT image may be generated from signals (e.g., electronic signals, digital signals, etc.). In some embodiments, the CT image may be used to identify at least a portion of the subject, classify at least a portion of the subject, diagnose at least a portion of the subject, determine a spatial location of at least a portion of the subject, and/or the like. The CT device 220 may have an isocenter 223. As used herein, the isocenter 223 of the CT apparatus 220 may refer to an intersection point between a rotational axis of the CT apparatus 220, a rotational axis of a radiation source of the CT apparatus 220, and a rotational axis of the patient table 260.

The RT device 240 may be used to treat, for example, perform radiation therapy on at least a portion of the identified subject based on the CT images. The RT device 240 may include a cyclotron, an induction accelerator, a linear accelerator (LINAC), and the like. In some embodiments, the CT device 220 and the RT device 240 may be disposed back-to-back or adjacent to each other, as shown in fig. 2. The CT device 220 and the RT device 240 may have the same rotational axis. Specifically, the CT device 220 may be connected to the RT device 240. In some embodiments, the CT device 220 and the RT device 240 may be provided separately from each other. In some embodiments, the CT device 220 and the RT device 240 may be mounted and/or fixed on the ground. In some embodiments, the CT device 220 and/or the RT device 240 may be mobile. For example, the CT device 220 and/or the RT device 240 may be moved using a movable device (e.g., a cart or wheels) mounted on the CT device 220 and/or the RT device 240. RT device 240 may have isocenter 243. As used herein, the isocenter 243 of the RT device 240 may refer to the rotational axis of the RT device 240, the intersection between the rotational axis of the radiation source of the RT device 240 and the rotational axis of the patient bed 260.

The patient bed 260 may be used to support and/or transfer at least a portion of a subject. The patient bed 260 may include a table top 261 and a support assembly 263. The support assembly 263 may support the table 261. The patient bed 260 may be movable in any direction, for example, a longitudinal direction (i.e., along the long axis of the tabletop 261 in the plane of the tabletop 261 in the retractable configuration), a transverse direction (i.e., along the short axis of the tabletop 261 in the plane of the tabletop 261 in the retractable configuration), or a direction oblique to the longitudinal and/or transverse directions. The movement of the patient bed 260 may be driven manually or by, for example, a motor. In some embodiments, the patient bed 260 may be moved using a movable device (e.g., a cart or wheels) mounted on the patient bed 260. In some embodiments, the machine direction may be described as the Y direction. The lateral direction may be described as the X direction. The X-direction and the Y-direction are in a plane containing the radiation source of the CT apparatus 220 or the RT apparatus 240 and the rotation centers of the RT apparatus 240 and the CT apparatus 220.

In some embodiments, the patient bed 260 may be used to support a subject during radiation therapy using an RT device (e.g., RT device 240). In some embodiments, the patient bed 350 can be used to support a subject during imaging using a CT device (e.g., CT device 220). In some embodiments, the CT device and the RT device may share the same patient bed 260. An object supported on a couch 260 may be CT scanned and radiation treated by moving the couch 260 from an imaging position to a treatment position during which the object does not need to be changed from couch to couch.

The measurement device 280 may be used to acquire data relating to the position and/or location of at least a portion of a component of the RT-CT device 200 (e.g., the patient bed 260, etc.). The data relating to the location of at least a portion of the components in RT-CT device 200 may be used to predict the location of at least a portion of the components in RT-CT device 200. The data relating to the position of at least a portion of the components (e.g., patient bed 260, etc.) in the RT-CT apparatus 200 may be data including static data, image data (e.g., images), or other data relating to the position of at least a portion of the components (e.g., patient bed 260, etc.) of the RT-CT apparatus 200 described elsewhere in this application. See, e.g., fig. 1 and its description.

The measurement device 280 may include at least one of an optical detection device, a range finder, an electromagnetic induction device, and the like, or a combination thereof. An exemplary optical detection device may include one or more photodetectors (e.g., a charge-coupled device (CCD)). In some embodiments, the optical detection device may comprise at least two photodetectors. The at least two photodetectors may be arranged as a photodetector lattice. The photodetector lattice can be one-dimensional, two-dimensional (2D), three-dimensional (3D), etc. In some embodiments, the optical detection device may acquire images related to a particular region of at least a portion of a component (e.g., a patient bed 260, etc.) in the RT-CT device 200. For example, the image may relate to a particular region including a reference point at the bottom of the patient bed 260. A reference point at the bottom of the patient bed 260 may be aligned with the isocenter 223 of the CT device 220 and/or the isocenter 243 of the RT device 240. Exemplary rangefinders may include ultrasonic rangefinders, laser rangefinders, radar rangefinders, and the like. The rangefinder may be used to determine the distance and/or direction from a reference point on the patient's bed to the rangefinder. Exemplary electromagnetic induction devices may include magnetic induction coils, electromagnetic transmitters (EMLs), electromagnetic receivers, and the like. In some embodiments, the magnetic induction coil may be connected to a patient bed 260. An electromagnetic Emitter (EML) may generate a magnetic field. When the patient bed 260 is moved in a magnetic field, the magnetic induction coil may generate an electromagnetic signal including motion information of the patient bed 260. The electromagnetic signal including the motion information of the patient bed 260 may be received by an electromagnetic receiver.

In some embodiments, the measurement device 280 may include a first measurement device and a second measurement device. In some embodiments, the first and second measurement devices may be applied to the CT device 220 and the RT device 240, respectively. For example, a first measurement device may be used to determine a first amount of subsidence of the patient bed 260 at the imaging location where the CT device 220 is located. The second measurement device may be used to determine a second amount of subsidence of the patient bed 260 at the treatment location where the RT device 240 is located. In some embodiments, the first measurement device and/or the second measurement device may both be applied to the RT device 240 and/or the CT device 220. For example, the first and second measurement devices may cooperatively determine the first and/or second sinkage. The first measurement device may be the same as or different from the second measurement device.

The measurement device 280 may be placed in a suitable location in the space in which the RT-CT device 200 is located. In some embodiments, the measurement device 280 may be connected to the CT device 220 and/or the RT device 240. For example, a first measurement device may be connected to the base of the CT device 220 and/or a second measurement device may be connected to the base of the RT device 240. In some embodiments, the measurement device 280 may be connected to the patient bed 260. For example, the rangefinder may be attached to a specific area on a patient bed. In some embodiments, the measurement device 280 may be disposed relative to the CT device 220, the RT device 240, and/or the patient bed 260. For example, the measurement device 280 may be mounted on the floor below the patient bed 260. As another example, the measurement device 280 may be mounted on a ceiling above the patient bed 260. As another example, the measurement device 280 may be mounted on the auxiliary support device to be parallel to the tabletop 261 of the patient bed 260. In some embodiments, the measurement device 280 may be configured to align with the isocenter 223 of the CT device 220 or the isocenter 243 of the RT device 240. In some embodiments, the measurement device 280 may be configured to be offset with respect to the isocenter 223 of the CT device 220 or the isocenter 243 of the RT device 240.

The description is intended to be illustrative, and not to limit the scope of the application. Many alternatives, modifications, and variations will be apparent to those skilled in the art. The features, structures, methods, and other features of the exemplary embodiments described herein may be combined in various ways to obtain additional and/or alternative exemplary embodiments. For example, the RT-CT device 200 may also include an imaging device, such as a PET device, an MRI device, and the like. Also for example, the measurement device 280 may include one or more sensors (e.g., a speed sensor, a displacement sensor, an accelerator sensor, etc.). One or more sensors may be used to acquire data related to the position of at least a portion of the components in RT-CT device 200.

Fig. 3 is a schematic diagram of exemplary hardware and/or software components of an exemplary computing device 300 on which processing device 120 may be implemented in accordance with some embodiments of the present application. As shown in FIG. 3, computing device 300 may include a processor 310, memory 320, input/output (I/O)330, and communication ports 340.

The processor 310 may execute computer instructions (e.g., program code) in accordance with the techniques described herein, as well as perform the functions of the processing device 120. The computer instructions may include, for example, routines, programs, objects, components, data structures, procedures, modules, and functions that perform the particular functions described herein. For example, processor 310 may process image data obtained from IGRT device 110, memory 130, terminal 140, and/or any other component of diagnostic and therapy system 100. In some embodiments, processor 310 may include one or more hardware processors, such as microcontrollers, microprocessors, Reduced Instruction Set Computers (RISC), Application Specific Integrated Circuits (ASIC), application specific instruction set processors (ASIP), Central Processing Units (CPU), Graphics Processing Units (GPU), Physical Processing Units (PPU), microcontroller units, Digital Signal Processors (DSP), Field Programmable Gate Arrays (FPGA), higher order RISC machines (ARM), Programmable Logic Devices (PLD), any circuit or processor capable of executing one or more functions, or the like, or any combination thereof.

For illustration only, only one processor is depicted in computing device 300. It should be noted, however, that the computing device 300 of the present disclosure may also include multiple processors, whereby operations and/or method steps performed by one processor as described herein may also be performed by multiple processors, either jointly or separately. For example, if in the present disclosure the processors of computing device 300 perform both operations a and B, it should be understood that operations a and B may also be performed by two or more different processors in computing device 300, either collectively or individually (e.g., a first processor performing operation a and a second processor performing operation B, or a first processor and a second processor performing operations a and B collectively).

Memory 320 may store data/information obtained from IGRT device 110, memory 130, terminal 140, and/or any other component of diagnostic and therapy system 100. In some embodiments, memory 320 may include mass storage, removable storage, volatile read-write memory, read-only memory (ROM), and the like, or any combination thereof. For example, mass storage may include magnetic disks, optical disks, solid state drives, and the like. Removable memory may include flash drives, floppy disks, optical disks, memory cards, compact disks, magnetic tape, and the like. Volatile read and write memory can include Random Access Memory (RAM). RAM may include Dynamic RAM (DRAM), double-data-rate synchronous dynamic RAM (DDR SDRAM), Static RAM (SRAM), thyristor RAM (T-RAM), zero-capacitance (Z-RAM), and the like. Exemplary read-only memories may include mask read-only memory (MROM), programmable read-only memory (PROM), erasable programmable read-only memory (EPROM), electrically erasable programmable read-only memory (EEPROM), compact disc read-only memory (CD-ROM), digital versatile disc read-only memory (dvd-ROM), and the like. In some embodiments, memory 320 may store one or more programs and/or instructions to perform the example methods described in this disclosure. For example, the memory 320 may store a program of the processing device 120 for determining a target flip angle plan.

I/O330 may input and/or output signals, data, information, and the like. In some embodiments, I/O330 may enable a user to interact with processing device 120. In some embodiments, I/O330 may include input devices and output devices. Exemplary input devices may include a keyboard, mouse, touch screen, microphone, etc., or any combination thereof. Exemplary output devices may include a display device, speakers, printer, projector, or the like, or any combination thereof. Examples of a display device may include a Liquid Crystal Display (LCD), a Light Emitting Diode (LED) based display, a flat panel display, a curved screen, a television device, a Cathode Ray Tube (CRT), a touch screen, and the like, or any combination thereof.

The communication port 340 may be connected to a network (e.g., network 120) to facilitate data communication. The communication port 340 may establish a connection between the processing device 120 and the IGRT device 110, memory 130 and/or terminal 140. The connection may be a wired connection, a wireless connection, any other communication connection that may enable data transmission and/or reception, and/or any combination of these connections. The wired connection may include, for example, an electrical cable, an optical cable, a telephone line, etc., or any combination thereof. The wired connection may include, for example, an electrical cable, an optical cable, a telephone line, etc., or any combination thereof. The wireless connection may include, for example, Bluetooth^TMLink, Wi-Fi^TMLink, WiMax^TMLinks, WLAN links, zigbee links, mobile network links (e.g., 3G, 4G, 5G, etc.), and the like or combinations thereof. In some embodiments, the communication port 340 may be and/or include a standardized communication port, such as RS232, RS485, and the like. In some embodiments, the communication port 340 may be a specially designed communication port. For example, the communication port 340 may be designed in accordance with the digital imaging and communications in medicine (DICOM) protocol.

FIG. 4 is a block diagram illustrating a system according to some embodiments of the present applicationA schematic diagram of exemplary hardware and/or software components of an exemplary mobile device 400 on which the terminal 140 is implemented. As shown in FIG. 4, mobile device 400 may include a communication platform 410, a display 420, a Graphics Processing Unit (GPU)430, a Central Processing Unit (CPU)440, I/O450, memory 460, and storage 490. In some embodiments, any other suitable component, including but not limited to a system bus or a controller (not shown), may also be included in mobile device 400. In some embodiments, the operating system 470 (e.g., iOS) is mobile^TM、Android^TM、Windows Phone^TMEtc.) and one or more applications 480 may be loaded from storage 490 into memory 460 for execution by CPU 440. The applications 480 may include a browser or any other suitable mobile application for receiving and presenting information from the processing device 120 related to image processing or other information. A user interacting with the information flow may be enabled via I/O450 and provided to processing device 120 and/or other components of diagnostic and therapy system 100 via network 150.

To implement the various modules, units, and functions thereof described herein, a computer hardware platform may be used as the hardware platform for one or more of the components described herein. A computer with user interface components may be used to implement a Personal Computer (PC) or any other type of workstation or terminal device. If programmed properly, the computer can also act as a server.

Fig. 5 is a block diagram of an exemplary processing device 120 shown in accordance with some embodiments of the present application. The processing device 120 may include an acquisition module 502, a control module 504, a processing module 506, and a storage module 508. At least a portion of processing device 120 may be implemented on a computing device as shown in fig. 3 or a mobile device as shown in fig. 4.

The acquisition module 502 may acquire data. In some embodiments, the data may be retrieved from IGRT device 110, memory 130, and/or terminal 140. In some embodiments, the data may include image data (e.g., radiological images, optical images, etc.), motion or position data (e.g., velocity, displacement, distance, acceleration, etc.) related to components in the IGRT device 110, instructions, etc., or a combination thereof. The instructions may be executable by a processor of the processing device 120 to perform the exemplary methods described herein. In some embodiments, the acquired data may be sent to the processing module 506 for further processing or stored in the storage module 508.

The control module 504 may control the operation of the acquisition module 502, the processing module 506, and/or the storage module 508, for example, by generating one or more control parameters. For example, the control module 504 may control the acquisition module 502 to acquire image data (e.g., radiological images, etc.) from the imaging device 112 of the IGRT device 110 and/or to acquire data relating to the position of the patient bed 116 from the measurement device 280. For another example, the control module 504 may control the processing module 506 to determine an amount of deformation (e.g., subsidence) of the patient bed 116 at a reference point when the patient bed is in the imaging position and/or the treatment position. For another example, the control module 504 may control movement of the bed 116 based on the amount of subsidence of the bed 116 at the reference point when the bed is in the treatment position. In some embodiments, control module 504 may receive real-time commands or retrieve predetermined instructions provided by a user (e.g., a physician) to control one or more operations of acquisition module 502 and/or processing module 506. For example, control module 504 may adjust acquisition module 502 and/or processing module 506 to generate image data (e.g., an image) according to real-time instructions and/or predetermined instructions. In some embodiments, control module 504 may communicate with one or more other modules of processing device 120 to exchange information and/or data.

The processing module 506 may process data provided by various modules of the processing device 120. In some embodiments, the processing module 506 may process the radiological images related to at least a portion of the subject to determine the amount of subsidence of the patient bed 116 at the reference point when the patient bed 116 is in the imaging position. In some embodiments, the processing module 506 may determine the amount of subsidence at the patient bed 116 at the reference point based on data related to the motion or position of the patient bed 116 acquired by the measurement device 280 when the patient bed 116 is in the treatment position.

The storage module 508 may store information. Information may include programs, software, algorithms, data, text, numbers, images, and some other information. For example, the information may include image data (e.g., radiological images, optical images, etc.), motion or position data (e.g., velocity, displacement, acceleration, spatial position, etc.) related to a component (e.g., the patient bed 116) in the IGRT device 110, instructions, etc., or a combination thereof. In some embodiments, the storage module 508 may store programs and/or instructions that may be executed by a processor of the processing device 120 to retrieve data to determine a spatial location of at least a portion of an object.

In some embodiments, one or more of the modules shown in fig. 5 may be implemented in at least a portion of the diagnostic and therapy system 100 shown in fig. 1. For example, the acquisition module 502, the control module 504, the processing module 506, and/or the storage module 508 may be integrated into a console (not shown). Through the console, the user can set parameters for scanning the object, control the imaging process, control parameters for reconstructing the image, etc. In some embodiments, the console may be implemented via the processing device 120 and/or the terminal 140.

Fig. 6 is a flow chart of an exemplary process 600 for determining an amount of deformation at a treatment location relative to an imaging location, according to some embodiments of the present application. In some embodiments, one or more operations of the process 600 shown in fig. 6 may be implemented in the diagnostic and therapy system 100 shown in fig. 1. For example, the process 600 shown in fig. 6 may be stored in the memory 130 in the form of instructions and invoked and/or executed by the processing device 120 (e.g., the processor 310 of the computing device 300 shown in fig. 3, the GPU 430 or the CPU440 of the mobile device 400 shown in fig. 4).

In 602, a first amount of deformation of a patient's bed at a reference point may be determined. The first amount of deformation of the bed may correspond to a first operative position of the bed. Operation 602 may be performed by processing module 506. The first operating position of the patient bed may refer to an imaging position in which an imaging device (e.g., imaging device 920) is located. When the patient bed is in the first operating position, a reference point on the patient bed (e.g., point C as shown in fig. 9) may be vertically aligned with the isocenter of the imaging device (e.g., isocenter 923 of imaging device 920). Compared to an ideal state in which the patient bed is not sunken, a first deformation amount of the patient bed at the reference point may result in a change of the position of the patient bed at the reference point due to the weight of the carrying object and/or the patient bed. For example, the first amount of deformation of the patient's bed may comprise a first amount of subsidence. Further, a first amount of subsidence of the patient ' S bed at the reference point due to an ideal state when the weight of the load bearing object and/or the patient ' S bed is not subsided with respect to the patient ' S bed may be determined based on the change in the position of the reference point in the vertical direction (e.g., an amount of subsidence S1 as shown in fig. 9).

In some embodiments, a first amount of deformation of the patient's bed at the reference point may be determined from an image associated with the reference point according to process 800 as described in fig. 8. The images may be CT images, PET images, MR images, or the like, or a combination thereof.

In some embodiments, a first amount of deformation of the patient's bed at the reference point may be determined by using a measurement device (e.g., a first measurement device 980-1 and/or a second measurement device 980-2 as shown in fig. 9). For example, a first actual distance from the reference point to the measuring device in an actual state when the patient bed sinks (e.g., a distance h1 as shown in fig. 9) may be determined by using the measuring device. A first desired distance from the reference point to the measuring device in a theoretical state in which the patient bed is not sunken (e.g. distance h0 as shown in fig. 9) can be determined from previous measurements. For example, information regarding a first desired distance from the reference point to the measurement device (e.g., distance h0 as shown in FIG. 9) may be retrieved from a memory (e.g., memory 130, storage module 508, etc.). The first deformation amount (e.g., the dip S1 shown in fig. 9) may be determined from a difference between a first actual distance (e.g., the distance h1 shown in fig. 9) and a first ideal distance (e.g., the distance h0 shown in fig. 9) between the reference point and the measuring device. Further, the first amount of deformation (e.g., the first amount of subsidence) may be equal to a difference between the first actual distance (e.g., distance h1 as shown in fig. 9) and the first ideal distance (e.g., distance h0 as shown in fig. 9) in the vertical direction (e.g., the Z direction in fig. 9).

In 604, a second shape variable of the patient's bed at the reference point may be determined. The second form of the patient bed may correspond to a second operative position of the patient bed. Operation 604 may be performed by processing module 506. The second operating position of the patient bed may refer to a treatment position at which a treatment device (e.g., treatment device 940) is located. When the patient bed is in the second operating position, a reference point on the patient bed (e.g., point C as shown in fig. 9) may be vertically aligned with the isocenter of the treatment apparatus (e.g., isocenter 943 of treatment apparatus 940). The second form of variation of the bed at the reference point may be related to a change in position relative to the reference point in an ideal state where the bed is not sunken (e.g., the weight carried causes the bed to be sunken, the weight of the bed causes the bed to be sunken). For example, the second form variable of the patient's bed may include a second amount of subsidence. A second amount of subsidence of the patient ' S bed at the reference point due to an ideal state when the weight of the subject and/or the patient ' S bed is not subsided with respect to the patient ' S bed may be determined based on the change in the position of the reference point in the vertical direction (e.g., an amount of subsidence S2 as shown in fig. 9).

In some embodiments, the second shape variable of the patient's bed at the reference point may be determined based on a measurement device (e.g., the first measurement device 980-1 or the second measurement device 980-2 as shown in fig. 9). For example, a second actual distance from the reference point to the measuring device in an actual state of the bed being sunken (e.g. distance h2 as shown in fig. 9) may be determined by using the measuring device. A second desired distance from the reference point to the measuring device in a theoretical state in which the patient's bed is not sunken (e.g. distance h0 as shown in fig. 9) may be determined based on the previous measurements. For example, information regarding a second desired distance (e.g., distance h0 as shown in fig. 9) from the reference point to the measurement device in a desired state in which the patient's bed is not sinking may be retrieved from a memory (e.g., memory 130, storage module 508, etc.). The second shape variable (e.g., convergence S2 as shown in fig. 9) may be determined based on a difference between a second actual distance (e.g., distance h2 as shown in fig. 9) and a second ideal distance from the reference point to the measurement device (e.g., distance h0 as shown in fig. 9). Further, the second form variable (e.g., the second amount of sinking) may be equal to a difference between the second actual distance (e.g., distance h2 as shown in fig. 9) and the ideal distance (e.g., distance h0 as shown in fig. 9) in the vertical direction (e.g., the Z direction in fig. 9).

At 606, a difference between the first and second deformation amounts may be determined. Operation 606 may be performed by processing module 506. In some embodiments, the difference between the first and second deformation amounts may be determined based on a difference between a first actual distance from the reference point to the measurement device when the patient's bed is in the first operating position (e.g., distance h1 as shown in fig. 9) and a second actual distance from the reference point to the measurement device when the patient's bed is in the second operating position (e.g., distance h2 as shown in fig. 9).

In 608, a second operating position of the patient bed may be adjusted based on a difference between the first and second amounts of deformation. Operation 608 may be performed by processing module 506. In some embodiments, when the patient bed is in the second working position relative to the first working position, the second working position of the patient bed may be adjusted to compensate for the patient bed's convergence at the reference point such that at least a portion of the subject may be aligned with the isocenter of the treatment apparatus (e.g., RT apparatus 240) for treatment. For example, the patient bed may deflect or sink when moved from the first operating position to the second operating position (e.g., from the imaging device to the treatment device). The amount of deformation of the patient's bed in the second operating position relative to the first operating position may be related to the difference between the first amount of deformation of the patient's bed and the second amount of deformation of the patient's bed. The patient bed may be raised or lowered according to a difference between the first amount of deformation of the patient bed and the second amount of deformation of the patient bed. Thus, at least a portion of the subject may be aligned with the isocenter of the treatment device (e.g., RT device 240) for treatment.

It should be noted that the foregoing is provided for illustrative purposes only and is not intended to limit the scope of the present application. Many variations and modifications will occur to those skilled in the art in light of the teachings herein. However, variations and modifications may be made without departing from the scope of the present application. For example, operations 602 and 604 may not be necessary. Then, a first actual distance and a second actual distance from the reference point to the measuring device in the actual case of a sinking of the patient bed can be determined, respectively. Also, the amount of deformation of the patient's bed relative to the second working position (e.g., treatment position) of the first working position may be determined based on the difference between the first actual distance and the second actual distance. As another example, the process 600 may include obtaining motion data associated with a patient bed acquired by a measurement device.

Fig. 7 is a flow chart of an exemplary process 700 for determining an amount of deformation of a patient's bed at a treatment location relative to an imaging location, shown in accordance with some embodiments of the present application. In some embodiments, one or more operations of process 700 shown in fig. 7 may be implemented in diagnostic and therapy system 100 shown in fig. 1. For example, the process 700 shown in fig. 7 may be stored in the memory 130 in the form of instructions and invoked and/or executed by the processing device 120 (e.g., the processor 310 of the computing device 300 shown in fig. 4, the GPU 430 or the CPU440 of the mobile device 400 shown in fig. 4).

In 702, an amount of displacement of a reference point on a patient's bed between a first operating position and a second operating position may be determined by using at least one measuring device. Operation 702 may be performed by processing module 506. As used herein, the amount of displacement of the reference point on the patient's bed may refer to a change in position of the reference point on the patient's bed in the space in which the medical device (e.g., RT-CT device 200) is located when the patient's bed is moved from the first operating position to the second operating position. Medical devices (e.g., RT-CT device 200) may include an imaging device (e.g., CT device 220) and a therapy device (e.g., RT device 240). The first operating position of the patient bed may refer to an imaging position in which an imaging device (e.g., CT device 220) is located. The second operating position of the patient bed may refer to a treatment position where a treatment device (e.g., RT device 240) is located. The reference point on the patient bed may be determined based on the isocenter of the imaging device (e.g., isocenter 223 of CT device 220). For example, the reference point may be a point on the patient bed that is vertically aligned with the isocenter of the imaging device (e.g., isocenter 223 of CT device 220) when the patient bed is in the first operating position.

In some embodiments, the displacement amount of the reference point on the patient bed may be directly obtained from the at least one measurement device. In some embodiments, the amount of displacement of the reference point on the patient's bed may be determined by the processing module 506 based on other static data related to the location of the reference point (e.g., the distance of the reference point on the patient's bed to the measurement device, the angle between the reference point on the patient's bed and the measurement device). For example, the displacement of a reference point on the patient bed may be determined based on a laser triangulation algorithm. Further, at least one measurement device (e.g., a laser range finder) may emit laser light to the patient bed, and the patient bed may reflect the laser light to the at least one measurement device (e.g., a laser interferometer). The amount of displacement of the reference point on the patient's bed can be determined based on the reflected laser light and the emitted laser light by using a laser triangulation algorithm. As another example, the amount of displacement of the reference point on the patient's bed may be determined based on images associated with the reference point acquired by at least one measurement device (e.g., an optical detector). Further, at least one measurement device (e.g., an optical probe) may determine the amount of displacement of the reference point based on the image by, for example, an edge detection algorithm, a center detection algorithm, or the like.

In 704, an amount of deformation of the patient's bed at the reference point may be determined based on an amount of displacement of the reference point on the patient's bed. The amount of deformation of the patient's bed at the reference point may correspond to the second operative position of the patient's bed. Operation 704 may be performed by processing module 506. The amount of deformation (e.g., the amount of subsidence) of the patient's bed at the reference point is related to the component of the amount of displacement of the reference point on the patient's bed in the vertical direction (e.g., the Z-direction as shown in fig. 2).

In 706, a second operating position of the patient bed may be adjusted based on an amount of deformation of the patient bed at the reference point. Operation 706 may be performed by processing module 506. In some embodiments, when the patient bed is in a second working position relative to the first working position, the second working position of the patient bed may be adjusted to compensate for the patient bed's convergence at the reference point such that at least a portion of the subject may coincide with the isocenter of the treatment device (e.g., RT device 240) for treatment. For example, as the patient bed moves from the first operating position to the second operating position (e.g., from the imaging device to the treatment device), the patient bed deflects or sinks with the amount of deformation determined in 704. The bed can be raised or lowered depending on the amount of deformation. Thus, at least a portion of the subject may coincide with the isocenter of the treatment device (e.g., RT device 240) for treatment.

It should be noted that the foregoing is provided for illustrative purposes only and is not intended to limit the scope of the present application. Many variations and modifications will occur to those skilled in the art in light of the teachings herein. However, variations and modifications may be made without departing from the scope of the present application. For example, process 700 may include obtaining static data related to the position of a patient bed acquired by a measurement device. As another example, operation 706 may not be necessary.

Fig. 8 is a flow chart of an exemplary process 800 for determining an amount of deformation of a patient's bed at a reference point of an imaging location, according to some embodiments of the present application. In some embodiments, one or more operations of the process 800 shown in fig. 8 may be implemented in the diagnostic and therapy system 100 shown in fig. 1. For example, the process 800 shown in fig. 8 may be stored in the memory 130 in the form of instructions and invoked and/or executed by the processing device 120 (e.g., the processor 310 of the computing device 300 shown in fig. 3, the GPU 430 or the CPU440 of the mobile device 400 shown in fig. 4). Operation 602 may be performed in accordance with process 800.

In 802, an image acquired by an imaging device including a reference point may be acquired. Operation 802 may be performed by acquisition module 502. The imaging device may comprise a medical imaging device, such as a CT device, CBCT device, PET device, MR device, etc., or a combination thereof. The images may be acquired from an imaging device (e.g., CT device 220), memory 130, terminal 140, or any other memory. The reference point may be a point on the patient bed that is vertically aligned with the isocenter of the imaging device (e.g., the isocenter of the CT device 220). The reference point may be a point in the image that can be identified.

In 804, a first location of a reference point may be determined based on the image. Operation 804 may be performed by processing module 506. In some embodiments, a coordinate system may be applied in the image. The coordinate system may be a 2D or 3D coordinate system. Further, the coordinate system in the image may have the center of the image as the origin of coordinates. The first position of the reference point may be a first coordinate represented by a coordinate system in the image. A first coordinate of a reference point on the patient bed may be obtained from a coordinate system in the image. As used herein, the first coordinate of the reference point may refer to an actual position of the reference point as represented by the coordinate system in the image when the patient bed is submerged. The sinking of the bed may be caused by the weight carried and/or the weight of the bed.

At 806, a second location of the reference point may be determined based on the image. The second position of the reference point may be a second coordinate represented by a coordinate system in the image. The second coordinate of the reference point may refer to an ideal position of the reference point represented by the coordinate system in the image when the bed is not sunken.

In some embodiments, the second coordinate may be determined based on one or more of the following operations. The location of the isocenter of the imaging device (e.g., isocenter 223 of CT device 220) may be determined in the image. The coordinates of the isocenter of the imaging device (e.g., isocenter 223 of CT device 220) may be represented in a coordinate system in the pass-through image. The isocenter of the imaging device may correspond to a scan center of the imaging device, which corresponds to the center of the image. For example, the coordinates of the isocenter of the imaging device may be equal to the coordinates of the scan center of the imaging device. For another example, the coordinates of the isocenter of the imaging device may be determined based on the coordinates of the scan center of the imaging device, a displacement of the isocenter of the imaging device, or a displacement of the scan center of the imaging device. The displacement of the isocenter of the imaging device or the displacement of the scan center of the imaging device may be configured by a user of the medical system 100. Then, when the bed is not sunken, the second coordinate of the reference point may be determined based on the coordinate of the isocenter of the imaging apparatus and the position of the table top of the bed of the image in an ideal state. The position information of the table top of the patient table in the image in the ideal state in which the table is not sunken can be obtained from, for example, a pre-measurement. For example, positional information in the image regarding the tabletop of the patient bed in an ideal state may be retrieved from a memory (e.g., memory 130, storage module 508, etc.).

In some embodiments, the second location of the reference point may be stored in a memory (e.g., memory 130, storage module 508, etc.). The second coordinate of the reference point may be retrieved from memory for future use.

In 808, an amount of deformation of the patient's bed at the reference point may be determined based on the first position of the reference point and the second position of the reference point. Operation 808 may be performed by processing module 506. An amount of deformation of the bed at the reference point when the bed is in the imaging position may be determined based on a difference between the first position and the second position. Further, the amount of deformation of the patient's bed at the reference point may be determined based on a difference in the vertical direction between the first coordinate of the reference point and the second coordinate of the reference point.

It should be noted that the foregoing is provided for illustrative purposes only and is not intended to limit the scope of the present application. Many variations and modifications will occur to those skilled in the art in light of the teachings herein. However, variations and modifications may be made without departing from the scope of the present application. For example, operation 802 may not be necessary. As another example, operations 802 and 804 may be performed simultaneously.