阅读说明：本技术 样本分析仪及其驱动方法 (Sample analyzer and driving method thereof ) 是由 刘隐明 吴万 于 2017-06-30 设计创作，主要内容包括：一种样本分析仪(100)及其驱动方法,包括气泵(1)、储气罐组(2)、采样组件(3)、反应组件(4)以及检测组件(5),气泵(1)用于在储气罐组(2)内建立正压和负压,正压和负压用于：驱动采样组件(3)采集生物样本；和/或,驱动反应组件(4)处理生物样本以形成待测液,反应组件(4)包括至少一个反应池；和/或,驱动待测液被检测组件(5)检测以获得检测信号。样本分析仪(100)成本较低。(sample analyzers (100) and a driving method thereof, the sample analyzers comprise an air pump (1), an air storage tank group (2), a sampling assembly (3), a reaction assembly (4) and a detection assembly (5), wherein the air pump (1) is used for establishing positive pressure and negative pressure in the air storage tank group (2), the positive pressure and the negative pressure are used for driving the sampling assembly (3) to collect a biological sample, and/or driving the reaction assembly (4) to process the biological sample to form a liquid to be detected, the reaction assembly (4) comprises at least reaction cells, and/or driving the liquid to be detected by the detection assembly (5) to obtain a detection signal, and the sample analyzers (100) are low in cost.)

sample analyzer, characterized by that, includes air pump, gas holder group, sampling subassembly, reaction unit and determine module, the air pump is used for establishing malleation and negative pressure in the gas holder group, malleation with the negative pressure is used for:

driving the sampling assembly to collect a biological sample;

and/or driving the reaction assembly to process the biological sample to form a liquid to be detected, wherein the reaction assembly comprises at least reaction cells;

and/or driving the liquid to be detected by the detection assembly to obtain a detection signal.

The sample analyzer of claim 1 wherein the set of gas tanks includes a th gas tank and a second gas tank, the air pump is connected to the th gas tank through a th control valve for establishing a th positive pressure in the th gas tank, and the air pump is connected to the second gas tank through a second control valve for establishing a th negative pressure in the second gas tank.

The sample analyzer of claim 2 wherein the air pump is a single head pump for pressurizing the air reservoir when the th control valve is ON and the second control valve is OFF, and for pressurizing the second air reservoir when the th control valve is OFF and the second control valve is ON.

The sample analyzer of claim 2 wherein the air pump is a single head pump or a dual head pump for pressurizing the th and second air reservoirs when the th control valve is open and the second control valve is open.

The sample analyzer of claim 2 further comprising a controller and a set of pressure sensors for sensing the pressure within the set of gas reservoirs and feeding back signals to the controller, the controller controlling the operation of the gas pump, the control valve, and the second control valve in response to the signals.

The sample analyzer of any of claims 2-5, wherein the sample analyzer has at least pressure relief valves in the flow path, and the th positive pressure is used to actuate the pressure relief valves.

The sample analyzer of claim 2 further comprising a waste reservoir coupled to the second reservoir and a liquid pump for drawing waste from the waste reservoir.

The sample analyzer of claim 7 wherein the waste reservoir has an th float switch disposed therein for detecting a level of liquid in the waste reservoir.

The sample analyzer of claim 7 further comprising a buffer cell connected between the second reservoir and the waste reservoir, the buffer cell configured to prevent waste in the waste reservoir from flowing back into the second reservoir.

The sample analyzer of claim 7 wherein a second float switch is disposed within the second reservoir for detecting a level of liquid within the second reservoir.

The sample analyzer of claim 2 further comprising a waste reservoir and a liquid pump for drawing waste within the waste reservoir and establishing a negative pressure within the waste reservoir.

The sample analyzer of any of claims 7-11, wherein the waste reservoir is connected to the reaction module and is configured to collect waste from the reaction module.

The sample analyzer of claim 5 wherein the set of gas tanks further includes a third gas tank, the gas tank being connected to the third gas tank by a third control valve for establishing a second positive pressure within the third gas tank by a positive pressure.

The sample analyzer of claim 13 further including a sixth control valve connected between the third reservoir and the flow restrictor and an flow restrictor, the flow restrictor being configured to relieve some of the pressure in the third reservoir.

The sample analyzer of claim 13 or 14 further comprising a sheath fluid reservoir and a flow chamber, wherein an outlet of the sheath fluid reservoir is connected to a sheath fluid inlet of the flow chamber, and wherein the third gas reservoir is in communication with the sheath fluid reservoir for urging sheath fluid in the sheath fluid reservoir into the flow chamber.

The sample analyzer of claim 15 wherein the controller is coupled to the third control valve for disconnecting the third air reservoir from the air reservoir through the third control valve when sheath fluid within the sheath fluid reservoir flows into the flow chamber.

The sample analyzer of claim 15 wherein the pressure sensor set further comprises a third pressure sensor connected to sense pressure within the third gas reservoir and/or the sheath fluid when the third control valve disconnects the third gas reservoir from the third gas reservoir and sheath fluid within the sheath fluid flows to the flow chamber.

The sample analyzer of claim 5 wherein the set of gas tanks further includes a fourth gas tank, the gas tank being connected to the fourth gas tank by a fourth control valve for establishing a third positive pressure within the fourth gas tank by a positive pressure.

The sample analyzer of claim 18, wherein the sample analyzer comprises a reservoir and an th reaction cell, the reservoir is connected to the th reaction cell, and the fourth gas container is connected to the reservoir for pushing the reagent in the reservoir into the th reaction cell.

The sample analyzer of claim 1 or 18, further comprising a quantitative pump having a diaphragm, a liquid chamber and an air chamber, the liquid chamber and the air chamber being located on opposite sides of the diaphragm, wherein the quantitative pump is connected to the set of air tanks, the positive pressure pushes the diaphragm to move in a direction toward the air chamber when the liquid chamber is connected to the set of air tanks, and the positive pressure pushes the diaphragm to move in a direction toward the liquid chamber when the air chamber is connected to the set of air tanks.

The sample analyzer of claim 20 wherein the sample analyzer comprises a liquid reservoir and an th reaction cell, the liquid reservoir being connected between the liquid reservoir and the th reaction cell.

The sample analyzer of claim 5 wherein the set of gas tanks further includes a fifth gas tank, the second gas tank connected to the fifth gas tank by a fifth control valve for establishing a second negative pressure within the fifth gas tank via the th negative pressure.

The sample analyzer of claim 22 further comprising a seventh control valve connected between the fifth reservoir and the second flow restriction, and a second flow restriction for relieving a portion of the pressure within the fifth reservoir.

The sample analyzer of claim 22 or 23 further comprising a second reaction cell, the fifth gas reservoir being connected to an outlet of the second reaction cell.

A method of driving a sample analyzer, the method comprising:

driving an air pump to establish positive pressure and negative pressure in the air storage tank group; and

the positive pressure and the negative pressure drive a flow path of the sample analyzer.

The driving method according to claim 25, wherein said driving the air pump to establish positive and negative pressures in the air tank group comprises:

the air pump is actuated to establish a th positive pressure in the th reservoir and a th negative pressure in the second reservoir, respectively.

The driving method as claimed in claim 26, wherein when the absolute value of the pressure of the th positive pressure is smaller than the th threshold, the air pump is driven to pressurize the th air tank, so that the absolute value of the pressure of the th positive pressure reaches the th threshold.

The driving method as claimed in claim 26, wherein when the absolute value of the pressure of the th positive pressure is equal to or greater than a th threshold value and the absolute value of the pressure of the th negative pressure is less than a second threshold value, the air pump is driven to pressurize the second air tank so that the absolute value of the pressure of the th negative pressure reaches the second threshold value.

The driving method according to claim 26, wherein when the absolute value of the pressure of the th positive pressure is equal to or greater than a th threshold value and is less than a third threshold value, and the absolute value of the pressure of the th negative pressure is equal to or greater than a second threshold value, the air pump is driven to pressurize the th air tank so that the absolute value of the pressure of the th positive pressure reaches the third threshold value.

The driving method as claimed in claim 26, wherein when the absolute value of the pressure of the th positive pressure is greater than or equal to a third threshold value, and the absolute value of the pressure of the th negative pressure is greater than or equal to a second threshold value and less than a fourth threshold value, the air pump is driven to pressurize the second air tank so that the absolute value of the pressure of the th negative pressure reaches the fourth threshold value.

The driving method as claimed in claim 26, wherein when the absolute value of the pressure of the positive pressure is greater than or equal to a third threshold value and less than a fifth threshold value, and the absolute value of the pressure of the negative pressure is greater than or equal to a fourth threshold value, the air pump is driven to pressurize the air tank so that the absolute value of the pressure of the positive pressure reaches the fifth threshold value.

The method of any of claims 26 to 31 and , wherein the positive pressure creates a second positive pressure within the third reservoir.

The driving method of claim 32, wherein said second positive pressure forces sheath fluid within said sheath fluid reservoir into a flow chamber.

The method of driving of claim 33 wherein said third air reservoir is disconnected from said th air reservoir before said second positive pressure forces sheath fluid within said sheath fluid reservoir into a flow chamber.

The driving method as claimed in claim 34, wherein a pressure change of said second positive pressure is detected by a third pressure sensor when said second positive pressure pushes the sheath fluid in said sheath fluid reservoir into the flow cell.

The method of driving of claim 32 wherein the positive pressure creates a third positive pressure within a fourth reservoir.

The method as claimed in claim 36, wherein the reservoir is connected to the th reaction cell, and the fourth gas container is connected to the reservoir for providing driving force for the reagent in the reservoir to enter the th reaction cell.

The method of claim 36, wherein the negative pressure creates a second negative pressure within a fifth air tank.

The driving method as claimed in claim 38, wherein the fifth gas container is conducted to an outlet of the second reaction tank to draw out the liquid in the second reaction tank by the second negative pressure.

The driving method according to claim 38, wherein:

the process of driving the air pump to establish a th positive pressure in the th air tank comprises:

the air pump establishes a th positive pressure with an absolute value of the pressure greater than a th preset value in the th air storage tank, and conducts the th air storage tank to the atmosphere, so that the absolute value of the pressure of the th positive pressure is reduced to the th preset value;

and/or the presence of a gas in the gas,

the process of driving the air pump to establish th negative pressure in the second air tank comprises the following steps:

the air pump establishes th negative pressure with the absolute pressure value larger than a second preset value in the second air storage tank, and conducts the second air storage tank to the atmosphere, so that the absolute pressure value of the second negative pressure is reduced to the second preset value;

and/or the presence of a gas in the gas,

the process at which the positive pressure establishes a second positive pressure within the third tank includes:

conducting the th air tank and the third air tank to ensure that the th positive pressure is the pressure in the third air tank so as to form a second positive pressure with the absolute value of the pressure larger than a third preset value;

and/or the presence of a gas in the gas,

the process of the negative pressure creating a second negative pressure within a fifth tank includes:

and conducting the fifth gas storage tank to the atmosphere to reduce the absolute value of the second negative pressure to the fourth preset value.

The driving method as claimed in any one of claims 25 to 31 and , wherein the quantitative pump of the sample analyzer comprises a liquid chamber and a gas chamber, the liquid chamber connects a liquid storage tank and a reaction tank, the driving method further comprises:

the liquid storage tank is communicated with the positive pressure so as to push liquid in the liquid storage tank into the liquid chamber by utilizing the positive pressure; and

the gas chamber is communicated with the positive pressure so as to push the liquid in the liquid chamber to the th reaction tank by using the positive pressure.