阅读说明：本技术 一种含有氟苯醚酰胺和克菌丹的杀菌剂组合物 (Bactericide composition containing fluorobenzene ether amide and captan ) 是由 邓竹根 王雯雯 谢钊 周阜宣 代伟 夏鸿儒 夏伟伟 于 2019-10-18 设计创作，主要内容包括：本发明提供一种含有氟苯醚酰胺和克菌丹的杀菌剂组合物,氟苯醚酰胺和克菌丹的重量比为1∶50-25∶1；该杀菌组合物可用于霜霉病的防治。(The invention provides a bactericide composition containing fluorobenzene ether amide and captan, wherein the weight ratio of the fluorobenzene ether amide to the captan is 1: 50-25: 1; the bactericidal composition can be used for preventing and treating downy mildew.)

1. A bactericide composition containing fluorobenzene ether amide and captan is characterized in that the weight ratio of the fluorobenzene ether amide to the captan is 1: 50-25: 1.

2. The germicide composition according to claim 1, characterized in that: can be prepared into a preparation acceptable for pesticide, and the total weight of the flufenican and the captan in the preparation accounts for 1 to 90 percent of the mass of the whole preparation.

3. The germicide composition according to claim 2, characterized in that: the total weight of the flufenide and the captan in the preparation accounts for 30-65% of the mass of the whole preparation.

4. The germicide composition according to claims 1 to 3, characterized in that: the dosage form of the bactericidal composition is granules, microcapsule suspending agents, missible oil, suspending agents, water dispersible granules, wettable powder and micro-emulsions.

5. Use of the fungicide composition according to claims 1 to 4 for the control of melon downy mildew.

Technical Field

The invention belongs to the field of pesticides, and particularly relates to a bactericide composition containing fluorobenzene ether amide and captan and application thereof.

Background

Downy mildew is also a worldwide disease, has the characteristics of quick transmission, serious morbidity and strong destructiveness, and brings great threat to the production of high-quality nuisanceless melons. Planting disease-resistant varieties and using chemical agents are the main methods for preventing and treating the diseases at present, but the working period of disease-resistant breeding is long, the repeated use of the chemical agents is easy to generate drug resistance, and the environment is polluted.

The fluorophenyletheramide is a pyrazole amide compound newly developed by university of China, and has a very good effect on rice and wheat sheath blight, common epidemic diseases of cucumber, tomato and potato, and downy mildew.

Captan is a broad-spectrum protective bactericide. The action mechanism of the method mainly influences the metabolism of the pyruvic acid of the thallus, has obvious inhibition effect on various enzymes, can also reduce the metabolism of phosphorus, reduce the content of adenosine triphosphate in the thallus and prevent the dispersion of conidia of some pathogenic bacteria. The pesticide can be widely applied to control various diseases on fruit trees, vegetables and various economic crops, can be sprayed on leaf surfaces and mixed with seeds, and is effective to diseases such as cucumber anthracnose, downy mildew, tomato early blight, potato late blight, grape downy mildew and the like, but the pesticide has no systemic treatment effect, so that the diseases are difficult to control once spreading.

The chemical pesticide is used alone for a long time, easily causes the diseases to generate drug resistance, causes the problems of increased dosage, reduced prevention effect and shortened lasting period, and is not beneficial to the sustainable development of the environment. The composition with the synergistic effect can not only obviously improve the actual prevention effect and reduce the dosage and the cost, but also help to avoid the generation of germ resistance and delay the generation speed of drug resistance, thereby solving the problems of resistance, cost and the like in the application process of the existing single pesticide. At present, related reports of compounding of fluorobenzene ether amide and captan are not seen at home and abroad.

Disclosure of Invention

The invention aims to provide a novel bactericidal composition with low resistance risk, low cost, good drug effect, long lasting period and obvious synergistic effect.

The invention provides the following technical scheme:

a bactericide composition contains fluorobenzene ether amide and captan, wherein the weight ratio of fluorobenzene ether amide to captan is 1: 50-25: 1.

The bactericidal composition can be prepared into a preparation acceptable for pesticides, and the total weight of the fluorobenzene ether amide and the captan in the preparation accounts for 1-90% of the total mass of the preparation.

The total weight of the fluorobenzene ether amide and the captan in the bactericidal composition accounts for 30-65% of the total mass of the preparation.

The dosage form of the bactericidal composition provided by the invention is granules, microcapsule suspending agents, missible oil, suspending agents, water dispersible granules, aqueous emulsion, wettable powder and microemulsion.

The bactericidal composition is used for preventing and treating downy mildew of melons, preferably pumpkins and melons.

Compared with the prior art, the invention has the following beneficial effects:

1. the bactericidal composition of the invention consists of two active ingredients with different action mechanisms, has obvious synergistic effect after being mixed, improves the control effect, and is also beneficial to overcoming and delaying the generation of drug resistance of pathogenic bacteria.

2-the composition medicament is mixed to reduce the dosage, thereby reducing the cost and lightening the pollution to the environment, having good safety and meeting the safety requirement of pesticide preparations.

Detailed Description

The following detailed description of specific embodiments of the present invention is provided in conjunction with examples, but it should be understood that the scope of the present invention is not limited to the specific embodiments.

Example bioassay one: toxicity determination of flufen-sodium and captan compounding on melon downy mildew

Test subjects: downy mildew of melon

The test was carried out by potting. Selecting sweet melon seedlings with consistent growth, selecting 15 pots of test melon seedlings for each treatment, and numbering for later use. Spray with a Potter spray tower at 50PSI pressure, 5mL per pot. Each agent is provided with 6 concentration gradients, and the treatment of spraying equal amount of clear water is used as a blank control. The method comprises the steps of taking downy mildew leaves collected from the field, dipping sporangium on the back of the downy mildew leaves in distilled water at about 10 ℃ by using a writing brush, and preparing sporangium suspension with the concentration of 3 x 105 per mL. Spraying and inoculating spore sac liquid after the treatment of the medicament for 24 hours, placing melon seedlings in an artificial climate box for cultivation after inoculation, investigating and recording the disease incidence after 15 days, and calculating the disease index and the prevention and treatment effect. The inhibitory median concentration EC50 was calculated by the least squares method, and the cotoxicity coefficient (CTC) was calculated by the Sun cloud Pepper method. The composition exhibits antagonism when CTC < 80, additive effect when CTC < 120, synergistic effect when CTC > 120. Measured virulence index (ATI) ═ (standard agent EC 50/test agent EC50) × 100; theoretical virulence index (TTI) ═ a agent virulence index × percentage of a in the mixture + B agent virulence index × percentage of B in the mixture; co-toxicity coefficient (CTC) × 100 [ measured toxicity index (ATI) of the mixture)/Theoretical Toxicity Index (TTI) of the mixture ].

TABLE 2 virulence determination of the complex formulation of flufen-sodium and captan for downy mildew of melon

As can be seen from the above table, the mixture ratio of the flufen-sodium and the captan is 1: 50-25: 1, and the flufen-sodium and the captan have a synergistic effect on the downy mildew of melons.

Bioassay example two: farmland prevention effect of compounding fluorobenzene ether amide and captan on pumpkin downy mildew

Test subjects: downy mildew of pumpkin

The test method comprises the following steps: each cell area was 25m2, repeated 3 times; the pesticide effect method for investigation before pesticide application and investigation after prevention and treatment comprises the following steps: randomly sampling 5 points in the test treatment area, grading the disease condition according to the relevant standards of the national field test, and calculating the control effect.

Test agent

Agent 1: 35% Fluorophenylamide-captan suspension (Fluorophenylamide: captan ═ 1: 6)

Medicament 2: 30% fluorobenzene ether amide-captan wettable powder (fluorobenzene ether amide: captan 1: 1)

Agent 3: 42% fluorobenzene ether amide captan water dispersible granule (fluorobenzene ether amide: captan ═ 20: 1)

Medicament 4: 35% Fluorophenylamide-captan suspension (Fluorophenylamide: captan 1: 4)

Control 1: 22% fluorophenyletheramide suspending agent

Control 2: wettable powder of 40% captan

TABLE 2 field control of pumpkin downy mildew with flufenide and captan

As shown in Table 2, compared with the single use, the compound of the flufen-sodium and the captan can improve the control effect on the pumpkin downy mildew, and the field observation shows that the compound is safe to pumpkin crops.

The present invention has been further described with reference to the examples, but the present invention is not limited to the above-described embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art.