阅读说明：本技术 三维器官模型、三维器官模型的打印方法、打印装置及打印设备 (Three-dimensional organ model, printing method and printing device for three-dimensional organ model and printing equipment ) 是由 符青真 于 2019-10-22 设计创作，主要内容包括：本发明涉及打印技术领域,尤其涉及一种三维器官模型、三维器官模型的打印方法、打印装置及打印设备。该三维器官模型的打印方法包括获取影像数据；基于影像数据进行三维建模以获得三维模型,三维模型包括组织器官部分、血管部分和病灶部分中的至少一个；将组织器官部分和/或血管部分分割为多个分段；为三维模型定义不同的打印属性,使得任意相邻的分段之间具有至少一个属性突变区域；打印获得三维器官模型。本发明所提供的三维器官模型、三维器官模型的打印方法、打印装置及打印设备能够直观、准确地区分各个分段,更好地规划手术路径以降低手术风险,实现精准医疗的目的。(The invention relates to the technical field of printing, in particular to a three-dimensional organ model, a printing method of the three-dimensional organ model, a printing device and printing equipment. The printing method of the three-dimensional organ model comprises the steps of obtaining image data; performing three-dimensional modeling based on the image data to obtain a three-dimensional model, the three-dimensional model including at least one of a tissue organ portion, a blood vessel portion, and a lesion portion; segmenting the tissue organ portion and/or the blood vessel portion into a plurality of segments; defining different printing attributes for the three-dimensional model, so that at least one attribute mutation region is arranged between any adjacent segments; and printing to obtain the three-dimensional organ model. The three-dimensional organ model, the printing method of the three-dimensional organ model, the printing device and the printing equipment provided by the invention can visually and accurately distinguish each segment, so that an operation path can be better planned to reduce operation risks, and the aim of accurate medical treatment is fulfilled.)

1. A method of printing a three-dimensional organ model, comprising:

acquiring image data;

performing three-dimensional modeling based on the image data to obtain a three-dimensional model, the three-dimensional model including at least one of a tissue organ portion, a blood vessel portion, and a lesion portion;

segmenting the tissue organ portion and/or the blood vessel portion into a plurality of segments;

defining different printing attributes for the three-dimensional model such that any adjacent segments have at least one attribute discontinuity region therebetween;

and printing to obtain the three-dimensional organ model.

2. The method of printing the three-dimensional organ model according to claim 1, wherein segmenting the tissue organ portion and/or the blood vessel portion into a plurality of segments comprises:

determining a segmentation plane that segments the tissue organ portion and/or the blood vessel portion into a plurality of the segments.

3. The method of printing the three-dimensional organ model according to claim 2, wherein segmenting the tissue organ portion and/or the blood vessel portion into a plurality of segments further comprises:

creating a partition plate based on the dividing plane, wherein the partition plate is arranged between any adjacent segments;

the properties of the segments on both sides of the partition are different from the properties of the partition.

4. The method of printing the three-dimensional organ model according to claim 3, wherein the plurality of spacers have the same properties and/or thickness.

5. The method of printing the three-dimensional organ model according to claim 3, wherein the properties of the segments on both sides of the partition are the same.

6. The method of printing the three-dimensional organ model according to claim 1, wherein any two adjacent segments have different properties at least at the portion where they are in contact, so that there is at least one property discontinuity region between the adjacent segments.

7. The method of printing the three-dimensional organ model of claim 6, wherein the segmenting comprises:

an outer shell portion and an inner portion;

the properties of the shell portions of any two adjacent segments are different.

8. The method of printing the three-dimensional organ model according to claim 1, wherein the attributes include color and/or transparency.

9. The method of printing the three-dimensional organ model according to claim 1, wherein three-dimensional modeling based on the image data includes:

extracting image data of the tissue organ part to establish a tissue organ three-dimensional model;

extracting image data of the blood vessel part to establish a blood vessel three-dimensional model;

and/or extracting image data of the focus part to establish a focus three-dimensional model;

fusing the three-dimensional model of the tissue organ, the three-dimensional model of the blood vessel and/or the three-dimensional model of the lesion to obtain the three-dimensional model.

10. The method of printing the three-dimensional organ model according to claim 1, wherein printing the three-dimensional organ model comprises:

slicing the three-dimensional model and obtaining slice data;

obtaining print control data based on the slice data;

performing three-dimensional printing based on the printing control data to obtain the three-dimensional organ model.

11. A printing apparatus, comprising:

the data acquisition module is used for acquiring image data;

a three-dimensional modeling module for performing three-dimensional modeling based on the image data to obtain a three-dimensional model including at least one of a tissue organ portion, a blood vessel portion, and a lesion portion;

a model segmentation module for segmenting the tissue organ portion and/or the blood vessel portion into a plurality of segments;

a print attribute definition module for defining print attributes for the three-dimensional model such that there is at least one attribute discontinuity region between the plurality of segments;

and the printing and forming module is used for printing to obtain the three-dimensional organ model.

12. The printing apparatus of claim 11, wherein the data acquisition module comprises:

the data preview module is used for checking the acquired image data;

and the image preprocessing module is used for judging whether the image is inverted or not.

13. The printing apparatus of claim 11, wherein the three-dimensional modeling module comprises:

an extraction module, configured to extract image data of a lesion portion, image data of the tissue and organ portion, and/or image data of the blood vessel portion from the image data, respectively;

the modeling module is used for establishing a focus three-dimensional model, a tissue organ three-dimensional model and/or a blood vessel three-dimensional model;

a fusion module for fusing the lesion three-dimensional model, the tissue organ three-dimensional model, and/or the vessel three-dimensional model to obtain the three-dimensional model.

14. The printing apparatus of claim 11, wherein the model segmentation module comprises:

a segmentation module for determining a segmentation plane, the segmentation plane segmenting the tissue organ portion and/or the blood vessel portion into a plurality of the segments.

15. The printing apparatus of claim 14, wherein the model segmentation module further comprises:

a partition creation module to create a partition based on the segmentation plane and fuse the partition with the three-dimensional model.

16. The printing apparatus of claim 11, wherein the model segmentation module further comprises:

a segmentation division module for dividing the segment into an outer shell portion and an inner portion.

17. The printing apparatus of claim 11, wherein the print forming module comprises:

a data processing module for slicing the three-dimensional model defining the print attributes and obtaining slice data, and obtaining print control data based on the slice data;

a printing module to perform three-dimensional printing based on the print control data to obtain the three-dimensional organ model.

18. A three-dimensional organ model comprising at least one of a tissue organ portion, a blood vessel portion, and a lesion portion;

the tissue organ portion and/or the vessel portion comprises a plurality of segments, wherein any two adjacent segments have at least one property mutation region therebetween.

19. The three-dimensional organ model of claim 18, wherein the properties of the tissue organ portion and/or the vessel portion are different from the properties of the lesion portion.

20. The three-dimensional organ model of claim 18, further comprising:

at least one partition disposed between any adjacent ones of said segments, said partition dividing said tissue organ portion and/or said vessel portion into a plurality of said segments;

the properties of the segments on both sides of the partition are different from the properties of the partition.

21. The three-dimensional organ model of claim 20, wherein the septa have the same properties and/or thickness.

22. The three-dimensional organ model of claim 20, wherein the properties of the segments on both sides of the partition are the same.

23. The three-dimensional organ model of claim 18, wherein any two adjacent segments have different properties at least at the portion in contact, such that there is at least one property discontinuity region between adjacent segments.

24. The three-dimensional organ model of claim 23, wherein the segmenting comprises:

an outer shell portion and an inner portion;

the properties of the shell portions of any two adjacent segments are different.

25. The three-dimensional organ model of claim 24, wherein said outer shell portion is formed of a colored transparent material and said inner portion is formed of a colorless transparent material.

26. The three-dimensional organ model of claim 18, wherein said attributes comprise color and/or transparency.

27. A printing apparatus, comprising:

a processor;

a memory for storing at least one instruction which is loaded and executed by the processor to implement the method of any one of claims 1-10.

Technical Field

The invention relates to the technical field of printing, in particular to a three-dimensional organ model, a printing method of the three-dimensional organ model, a printing device and printing equipment.

Background

With the development of scientific technology, human beings have made many medical advances, but in clinical medicine, some diseases still have the problems of low operation success rate and high risk. At present, three-dimensional printing technique has apparent application in the aspect of accurate medical treatment, and it can produce the 3D model completely unanimous with patient's organ according to patient's medical image data fast, and the doctor of being convenient for foresees the condition in the art from the multidimension degree is real before the art, plans the operation route and rehearsal operation, has greatly reduced the risk of operation, and simultaneously, in medical teaching, the student also can master the constitution of study organ according to the 3D model.

As is well known, some organs of the human body are segmented organs, for example, the liver can be divided into eight or ten five-lobe segments through arterial blood vessels, portal veins, hepatic veins and/or biliary tract systems, the lung can be divided into twenty five-lobe segments through arterial blood vessels and/or trachea, if it is known before an operation which segment of the organ the tumor is located in and the approximate position of the segment the tumor is located in, during the operation, a doctor only needs to find and excise the segment, the tumor can be excised, or the doctor directly finds the segment and excises the tumor in the segment; it is much simpler for a doctor to find the segmentation of an organ than to find a tumor, but since a tumor is usually inside an organ, it is still difficult for the doctor to accurately judge which segment the location of the tumor belongs to based on an existing three-dimensional printed model, and in the field of teaching, the existing organ model cannot intuitively and clearly distinguish the segments of the organ, and it is inconvenient for the student to learn and master the segments of the organ.

Therefore, there is a need for a three-dimensional organ model that can intuitively distinguish between segments.

Disclosure of Invention

The invention provides a three-dimensional organ model, a printing method of the three-dimensional organ model, a printing device and printing equipment.

The invention provides a printing method of a three-dimensional organ model, which is characterized by comprising the following steps:

acquiring image data;

performing three-dimensional modeling based on the image data to obtain a three-dimensional model, the three-dimensional model including at least one of a tissue organ portion, a blood vessel portion, and a lesion portion;

segmenting the tissue organ portion and/or the blood vessel portion into a plurality of segments;

defining different printing attributes for the three-dimensional model such that any adjacent segments have at least one attribute discontinuity region therebetween;

and printing to obtain the three-dimensional organ model.

Further, segmenting the tissue organ portion and/or the blood vessel portion into a plurality of segments comprises:

determining a segmentation plane that segments the tissue organ portion and/or the blood vessel portion into a plurality of the segments.

Further, segmenting the tissue organ portion and/or the blood vessel portion into a plurality of segments further comprises:

creating a partition plate based on the dividing plane, wherein the partition plate is arranged between any adjacent segments;

the properties of the segments on both sides of the partition are different from the properties of the partition.

Further, a plurality of the separators have the same property and/or thickness.

Further, the properties of the segments on both sides of the partition are the same.

Further, any two adjacent segments have different properties at least in the contact portion, so that at least one property mutation region is provided between the adjacent segments.

Further, the segmenting comprises:

an outer shell portion and an inner portion;

the properties of the shell portions of any two adjacent segments are different.

Further, the attributes include color and/or transparency.

Further, performing three-dimensional modeling based on the image data includes:

extracting image data of the tissue organ part to establish a tissue organ three-dimensional model;

extracting image data of the blood vessel part to establish a blood vessel three-dimensional model;

and/or extracting image data of the focus part to establish a focus three-dimensional model;

fusing the three-dimensional model of the tissue organ, the three-dimensional model of the blood vessel and/or the three-dimensional model of the lesion to obtain the three-dimensional model.

Further, the printing to obtain the three-dimensional organ model comprises:

slicing the three-dimensional model and obtaining slice data;

obtaining print control data based on the slice data;

performing three-dimensional printing based on the printing control data to obtain the three-dimensional organ model.

A second aspect of the present invention provides a printing apparatus comprising:

the data acquisition module is used for acquiring image data;

a three-dimensional modeling module for performing three-dimensional modeling based on the image data to obtain a three-dimensional model including at least one of a tissue organ portion, a blood vessel portion, and a lesion portion;

a model segmentation module for segmenting the tissue organ portion and/or the blood vessel portion into a plurality of segments;

a print attribute definition module for defining print attributes for the three-dimensional model such that there is at least one attribute discontinuity region between the plurality of segments;

and the printing and forming module is used for printing to obtain the three-dimensional organ model.

Further, the data acquisition module comprises:

the data preview module is used for checking the acquired image data;

and the image preprocessing module is used for judging whether the image is inverted or not.

Further, the three-dimensional modeling module includes:

an extraction module, configured to extract image data of a lesion portion, image data of the tissue and organ portion, and/or image data of the blood vessel portion from the image data, respectively;

the modeling module is used for establishing a focus three-dimensional model, a tissue organ three-dimensional model and/or a blood vessel three-dimensional model;

a fusion module for fusing the lesion three-dimensional model, the tissue organ three-dimensional model, and/or the vessel three-dimensional model to obtain the three-dimensional model.

Further, the model segmentation module comprises:

a segmentation module for determining a segmentation plane, the segmentation plane segmenting the tissue organ portion and/or the blood vessel portion into a plurality of the segments.

Further, the model segmentation module further comprises:

a partition creation module to create a partition based on the segmentation plane and fuse the partition with the three-dimensional model.

Further, the model segmentation module further comprises:

a segmentation division module for dividing the segment into an outer shell portion and an inner portion.

Further, the printing and molding module comprises:

a data processing module for slicing the three-dimensional model defining the print attributes and obtaining slice data, and obtaining print control data based on the slice data;

a printing module to perform three-dimensional printing based on the print control data to obtain the three-dimensional organ model.

A third aspect of the present invention provides a three-dimensional organ model including at least one of a tissue organ portion, a blood vessel portion, and a lesion portion;

the tissue organ portion and/or the vessel portion comprises a plurality of segments, wherein any two adjacent segments have at least one property mutation region therebetween.

Further, the properties of the tissue organ portion and/or the blood vessel portion are different from the properties of the lesion portion.

Further, the method also comprises the following steps:

at least one partition disposed between any adjacent ones of said segments, said partition dividing said tissue organ portion and/or said vessel portion into a plurality of said segments;

the properties of the segments on both sides of the partition are different from the properties of the partition.

Further, the separators have the same properties and/or thickness.

Further, the properties of the segments on both sides of the partition are the same. Further, any two adjacent segments have different properties at least in the contact portion, so that at least one property mutation region is provided between the adjacent segments.

Further, the segmenting comprises:

an outer shell portion and an inner portion;

the properties of the shell portions of any two adjacent segments are different.

Further, the outer shell portion is formed of a colored transparent material, and the inner portion is formed of a colorless transparent material.

Further, the attributes include color and/or transparency.

A fourth aspect of the present invention provides a printing apparatus comprising:

a processor;

a memory for storing at least one instruction which is loaded and executed by the processor to implement the method described above.

The technical scheme provided by the invention can achieve the following beneficial effects:

the invention provides a printing method of a three-dimensional organ model, which segments tissue organ parts and/or blood vessel parts in the printed three-dimensional organ model, and specifies that at least one attribute mutation area is arranged between any adjacent segments to distinguish the segments, thereby realizing intuitive and accurate recognition of the segments of the tissue organ parts and/or the blood vessel parts. Furthermore, the focus part is combined into the printed three-dimensional organ model, so that communication and communication between doctors and patients can be facilitated, and a doctor can accurately judge the position of the focus part, so that an operation path is better planned to reduce operation risks, and the aim of accurate medical treatment is further fulfilled.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.

FIG. 1 is a flow chart of a method for printing a three-dimensional organ model according to an embodiment of the present invention;

FIG. 2 is a flowchart illustrating an embodiment of the present invention for acquiring image data and three-dimensional modeling;

FIG. 3 is a detailed flow chart of three-dimensional modeling, segmentation, and defining print attributes provided by an embodiment of the present invention;

FIG. 4 is a detailed flowchart of printing a three-dimensional organ model according to an embodiment of the present invention;

FIG. 5 is a block diagram of a printing apparatus according to an embodiment of the present invention;

fig. 6 is a block diagram of a data acquisition module according to an embodiment of the present invention;

FIG. 7 is a block diagram of a three-dimensional modeling module provided by an embodiment of the present invention;

FIG. 8 is a block diagram of a model segmentation module according to an embodiment of the present invention;

fig. 9 is a block diagram of a print forming module according to an embodiment of the present invention;

FIG. 10 is a schematic structural view of a tissue organ portion according to an embodiment of the present invention;

FIG. 11 is a schematic structural diagram of a lung organ tissue according to an embodiment of the present invention;

FIG. 12 is a schematic structural view of a portion of a lung organ tissue according to an embodiment of the present invention;

FIG. 13 is a schematic structural diagram of an arterial dissection provided in accordance with an embodiment of the present invention;

FIG. 14 is an enlarged view of FIG. 13;

FIG. 15 is a schematic cross-sectional view of an arterial dissection provided in accordance with an embodiment of the invention;

FIG. 16 is a schematic structural diagram of a three-dimensional model segmentation provided by an embodiment of the present invention;

FIG. 17 is a schematic structural diagram of another three-dimensional model segmentation provided in the embodiments of the present invention;

fig. 18 is a schematic structural diagram of another three-dimensional model segmentation according to an embodiment of the present invention.

Reference numerals:

1-focal fraction;

2-a tissue organ portion;

21-liver organ tissue;

211-a housing portion;

212-an inner part;

22-lung organ tissue;

221-upper left leaf;

222-left lower lobe;

223-upper right leaf;

224-right middle leaf;

225-lower right lobe;

3-a vascular portion;

31-a true lumen segment;

311-inner membrane;

312-mesolamella;

313-true extraluminal membrane;

32-a false cavity section;

321-false extraluminal membrane;

4-a separator;

5-dividing the noodles;

6-a data acquisition module;

61-data preview module;

62-an image pre-processing module; 7-a three-dimensional modeling module;

71-an extraction module;

72-a modeling module;

73-a fusion module;

8-a model segmentation module;

81-a segmentation module;

82-a partition building module;

83-segmentation module;

9-a print attribute definition module;

10-printing a molding module;

101-a data processing module;

102-a print module;

11-a processor;

12-memory.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the following specific embodiments, which are obviously some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "inside", "outside", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, which are only for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and operate, and thus, should not be construed as limiting the present invention.

In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.

As shown in fig. 1, the present embodiment provides a printing method of a three-dimensional organ model, comprising the steps of:

in step S10, image data is acquired.

Specifically, in step S10, the acquired image data may be two-dimensional image data, three-dimensional image data, or other image data, and the image data is not specifically limited as long as the image data can be printed in accordance with the three-dimensional organ model. At present, most of the medical uses are image data such as Magnetic Resonance Imaging (MRI) data or Computed Tomography (CT) data; the image data may further include patient information, hospital information, machine model information, machine precision information, and the like.

Step S30, three-dimensional modeling is performed based on the image data to obtain a three-dimensional model including at least one of the tissue organ portion 2, the blood vessel portion 3, and the lesion portion 1.

It should be noted here that, when performing three-dimensional modeling, modeling may be performed according to actual requirements, specifically, when used in medical teaching, there may be no lesion part, that is, modeling of a lesion part is not performed when performing three-dimensional modeling, further, according to actual requirements, when performing three-dimensional modeling based on surgical analysis, modeling of a lesion part 1 must exist, where the tissue organ part 2 and the blood vessel part 3 may be selected according to actual requirements, that is, the tissue organ part 2 and the blood vessel part 3 may be included at the same time, modeling of the tissue organ part 2 may be performed separately, and modeling of the blood vessel part 3 may be performed separately.

As shown in fig. 2, specifically, the step S30 of performing three-dimensional modeling based on the image data includes:

in step S301, image data of the tissue and organ portion 2 is extracted to create a three-dimensional tissue and organ model.

In step S302, the image data of the blood vessel portion 3 is extracted to build a three-dimensional model of the blood vessel.

And/or step S303, extracting the image data of the lesion part 1 to establish a three-dimensional lesion model.

Step S304, fusing the tissue organ three-dimensional model, the blood vessel three-dimensional model and/or the focus three-dimensional model to obtain a three-dimensional model.

More specifically, since at least a part of the blood vessel portion 3 and the lesion portion 1 is located inside the tissue organ portion 2, and therefore, there are a plurality of cavities matching the blood vessel portion 3 and the lesion portion 1 inside the tissue organ portion 2, it is complicated to accurately construct a three-dimensional model of the tissue organ including the plurality of cavities based on the image data, and in order to simplify the procedure of constructing the three-dimensional model, the construction of the three-dimensional model of the tissue organ of the present embodiment may be such that an initial three-dimensional model of the tissue organ portion 2 including no cavities is constructed based on only the outer contour of the tissue organ portion 2 in the image data, and then the fusion of the three-dimensional model includes cutting out the region occupied by the blood vessel portion 3 and the lesion portion 1 from the initial three-dimensional model of the tissue organ portion 2 based on the position and size of the blood vessel portion 3 and the lesion portion 1 in the, thereby obtaining an actual three-dimensional model of the tissue organ portion 2 having a cavity matching the blood vessel portion 3 and the lesion portion 1, the tissue organ three-dimensional model, the blood vessel three-dimensional model and the lesion three-dimensional model being fused to form a three-dimensional model of the organ.

It should be noted here that, when the three-dimensional organ model is used for teaching, the three-dimensional organ model may not include the lesion part 1, that is, step S303 may not be performed when obtaining the three-dimensional model, and further, in the process of obtaining the three-dimensional organ model, the tissue organ three-dimensional model may be obtained alone, the blood vessel three-dimensional model may also be obtained alone, the tissue organ three-dimensional model may also be obtained, and the blood vessel three-dimensional model may also be obtained.

In step S50, the tissue organ portion 2 and/or the blood vessel portion 3 is segmented into a plurality of segments.

As shown in fig. 10, in step S50, the tissue and organ portion 2 may be segmented into a plurality of segments according to a medical segmentation method, for example, taking the liver organ tissue 21 as an example, the liver organ tissue 21 may be segmented into 5 segments and 8 segments according to the Couinaud liver segmentation method. As shown in FIG. 1, the 8 segments are respectively a tail-shaped leaf I, a left outer leaf upper segment II, a left outer leaf lower segment III, a left inner leaf IV, a right front leaf lower segment V, a right rear leaf lower segment VI, a right rear leaf upper segment VII and a right front leaf upper segment VIII. Specifically, the Couinaud liver segmentation method divides the liver into 8 independent segments according to functions, each segment has an inflow blood vessel and an outflow blood vessel of the segment and a bile duct system, the center of each segment is provided with a portal vein, a hepatic artery and a bile duct branch, the periphery of each segment is provided with an outflow blood vessel passing through the hepatic vein, the liver is divided into a right front segment and a right rear segment by a hepatic right vein, the liver is divided into a left lobe and a right lobe (or a right half liver and a left half liver) by a hepatic middle vein, the liver left lobe is divided into an inner side segment and an outer side segment by the hepatic left vein, the liver is divided into an upper segment and a lower segment by the portal vein, and the upper branch and the lower branch of the left portal vein and the right portal vein respectively enter the. According to this division, each segment is a separate unit, and the resection of any one segment does not affect the others, and in order to ensure liver survival, the resection must be performed along the blood vessels around these segments, i.e. the resection line is parallel to the hepatic veins, so that the centrally located portal vein, bile duct and hepatic arteries are preserved, i.e. the segments of the tissue organ portion 2 can generally be determined based on the distribution of the blood vessel portion 3. In practical applications, the tissue organ portion 2 may be segmented according to the distribution of the blood vessel portion 3 and/or other duct systems, in this embodiment, the duct system is a bile duct, wherein in the segmentation of the lung organ, the duct system may be a trachea, and the application does not limit the specific segmentation method.

Step S70, defining different print attributes for the three-dimensional model such that any adjacent segments have at least one attribute discontinuity between them.

Specifically, in step S70, in order to enable intuitive and accurate recognition of the respective segments of the tissue organ portion 2 and/or the blood vessel portion 3, different printing properties are defined for the three-dimensional model, i.e. such that different parts of the three-dimensional model are formed of different property materials. More specifically, in the process of defining the printing attributes, different colors or transparencies may be respectively used to represent different material attributes, or the colors and the transparencies may jointly represent different material attributes, so as to facilitate the definition of the printing attributes of the three-dimensional model; the printing attributes can also comprise hardness and softness, a user can print the three-dimensional organ models with different hardness and softness by using materials with different hardness and softness through setting the hardness and softness, the setting of the hardness and softness can be based on the whole three-dimensional organ model, namely, the hardness and softness of the whole three-dimensional organ model are consistent, and the setting can also be based on any one independent part in the three-dimensional organ model, namely, each part in the three-dimensional organ model can have different hardness and softness, and the three-dimensional organ model which is closer to the hand feeling of a real organ can be obtained through the adjustment of the hardness and softness.

Step S90, printing to obtain a three-dimensional organ model.

As shown in fig. 4, specifically, the three-dimensional modeling based on the video data in step S90 includes:

step 901, slicing the three-dimensional model and obtaining slice data.

At step 902, print control data is obtained based on the slice data.

And step 903, performing three-dimensional printing based on the printing control data to obtain a three-dimensional organ model.

The embodiment provides a printing method of a three-dimensional organ model, which segments a tissue organ part 2 and/or a blood vessel part 3 in the printed three-dimensional organ model, and specifies at least one attribute mutation area between any two adjacent segments to distinguish the segments, thereby realizing intuitive and accurate recognition of the segments of the tissue organ part 2 and/or the blood vessel part 3. Furthermore, the focus part 1 is combined into the printed three-dimensional organ model, so that communication between doctors and patients can be facilitated, and a doctor can accurately judge the position of the focus part 1, so that an operation path is better planned to reduce operation risks, and the aim of accurate medical treatment is further fulfilled.

As shown in fig. 3, in the present embodiment, the dividing of the tissue organ portion 2 and/or the blood vessel portion 3 into a plurality of segments in step S50 includes:

as shown in fig. 16, in step S501, a dividing plane 5 is determined, and the dividing plane 5 divides the tissue and organ part 2 and/or the blood vessel part 3 into a plurality of segments. Taking the liver organ tissue 21 as an example, the segmentation surface 5 of the liver organ tissue 21 is determined according to a medical segmentation method, and the liver organ tissue 21 is segmented into 8 segments by the segmentation surface 5.

As shown in fig. 16, in step S502, the partition plates 4 are created based on the dividing plane 5, wherein the partition plates 4 are provided between any adjacent segments, the partition plates 4 between the adjacent segments are such that there are regions of abrupt attribute change between the adjacent segments, and the segments of the liver organ tissue 21 can be distinguished by the partition plates 4.

In the present embodiment, in order to make the printed three-dimensional organ model recognize the segments of the tissue organ portion 2 and/or the blood vessel portion 3 more intuitively and accurately, for convenience of description, the liver organ tissue 21 is used for illustration, in the liver organ tissue 21, any two adjacent segments are separated by the partition plates 4, that is, the liver organ tissue 21 includes a plurality of partition plates 4, wherein the plurality of partition plates 4 may be connected with each other or independent of each other, and the plurality of partition plates 4 may be formed by materials with the same property or materials with different properties, and the thicknesses of the plurality of partition plates 4 may be the same or different. Further, the property of the segments on both sides of the partition plate 4 is different from that of the partition plate 4, specifically, the color or transparency of the partition plate 4 is different from that of the segments on both sides of the partition plate 4, or the color and transparency of the partition plate 4 are different from that of the segments on both sides of the partition plate 4, in order to make the partition plate 4 visually clear and not occupy too large a position to affect the observation of the internal structure, the thickness of the partition plate 4 may be set to 0.3mm to 2mm, in other embodiments, the thickness of the partition plate 4 is 0.6mm to 1.2 mm; in this embodiment, since the attribute of the partition plate 4 is different from the attribute of the segments on both sides of the partition plate 4, the boundary between the partition plate 4 and the segments on both sides thereof has an attribute abrupt change region.

Here, for example, fig. 11 is a schematic diagram of a lung segmentation model, in this embodiment, the lung organ tissue 22 may be divided into five segments, i.e., a lung organ tissue left upper lobe 221, a lung organ tissue left lower lobe 222, a lung organ tissue right upper lobe 223, a lung organ tissue right middle lobe 224, and a lung organ tissue right lower lobe 225, a lesion part 1 is located in the lung upper lobe 223, a partition 4 is provided between any two of the five segments, the partition 4 and the segments on both sides thereof have different attributes, i.e., at least one attribute mutation region is provided between the segments; further, the lung organ tissue 22 may be segmented according to other segmentation manners according to actual requirements, for example, the upper left lobe 221 of the lung organ tissue may be further segmented into a posterior tip segment, an anterior segment, an upper tongue lobe segment, and a lower tongue lobe segment, and the present application does not limit the specific segmentation of the lung organ tissue 22.

In this embodiment, any two of the 8 segments of the liver organ tissue 21 are separated by the partition plates 4, that is, the liver organ tissue 21 includes a plurality of partition plates 4, wherein the plurality of partition plates 4 may be connected to each other or may be independent of each other, and the plurality of partition plates 4 may be formed by materials with the same property or materials with different properties, and the thicknesses of the plurality of partition plates 4 may be the same or different, only by ensuring that at least one property mutation region exists between any two adjacent segments.

In this embodiment, fig. 16 shows a schematic flow chart of segmenting the tissue organ portion 2 and segmenting the tissue organ portion in a manner of creating the partition plate 4, where the example is a section v and a section vii of the liver organ tissue portion 21, specifically, the section v and the section vii are segmented by the segmentation surface 5, the segmentation surface 5 is determined according to the Couinaud liver segmentation method, and the creation of the partition plate 4 includes extracting the segmentation surfaces 5 of the section v and the section vii of the liver organ tissue portion 21 and offsetting the segmentation surfaces by a certain thickness in a direction perpendicular to the segmentation surface 5 to form the partition plate 4, more specifically, the offsetting direction may be along any side of the segmentation surface 5 or along both sides of the segmentation surface 5, and in practical applications, an appropriate offsetting direction may be selected according to an actual segmentation situation. The partition plate 4 is further fused with the three-dimensional model of the liver organ tissue 21 portion to obtain a segmented three-dimensional model of the segmented liver organ tissue 21 portion, that is, the position occupied by the partition plate 4 is cut off in the three-dimensional model of the liver organ tissue 21 portion, that is, a groove matched with the partition plate 4 is formed in the liver organ tissue 21 portion, and then the partition plate 4 is fused with the cut three-dimensional model of the liver organ portion.

Specifically, in order to enable the blood vessel portion 3 or the lesion portion 1 distributed in the tissue organ portion 2 to be observed from the outside of the model, the tissue organ portion 2 is formed of a colorless transparent material having a light transmittance of more than 80% and/or a colored transparent material having a light transmittance of more than 0% and less than 45%; the blood vessel portion 3 and the lesion portion 1 may also be formed of a colored transparent material and/or a colored opaque material, and the light transmittance of the opaque colored material is less than 10%, however, for the convenience of distinction, the tissue organ portion 2, the blood vessel portion 3 and the lesion portion 1 are respectively formed of materials with different colors and/or transparencies, and how to set the settings may be set according to the actual situation of the user, which is not limited in this application. In some embodiments, the blood vessel portion 3 may further include arteries and veins, and therefore, the blood vessel portion 3 may further be formed by forming the arteries and veins from different materials with different colors and/or transparencies, and generally, in order to further facilitate the user's identification and defecation, the colors of the arteries and veins may be consistent with the colors on the conventional medical anatomical atlas, i.e., the arteries are formed from red material and the veins are formed from blue material.

Furthermore, since the transparency of the colored transparent material is lower than that of the colorless transparent material, the tissue organ portion 2 may be formed of a colorless transparent material, and the partition plate 4 may be formed of a white material, in this embodiment, the light transmittance of the white material is less than 10%, which may be considered as one of opaque materials, and the blood vessel portion 3 and the lesion portion 1 may be formed of a colored opaque material, so that the shape, structure, and distribution position of the blood vessel portion 33 and the lesion portion 1 in the tissue organ portion 2 can be clearly displayed, so that a physician can accurately judge the section where the lesion portion 1 is located to plan the surgical path, and each section of the tissue organ portion 2 can be distinguished by the partition plate 4, and the partition plate 4 is set to be white, so that the brightness of the three-dimensional organ model can be further improved; in other embodiments, the lesion portion 1 may also be formed by a transparent color material, so that the distribution of the blood vessel portion 3 in the lesion portion 1 can also be clearly displayed, and the accuracy of the surgical planning performed by the doctor is further improved.

In this embodiment, the three-dimensional organ model printed by the above-mentioned printing method for three-dimensional organ model may not include the partition 4, i.e., the step of dividing the tissue organ portion 2 and/or the blood vessel portion 3 into a plurality of segments may not include step S502, so that any two adjacent segments have different attributes at least at the contacted portion, i.e., so that at least one attribute abrupt change region is provided between the adjacent segments, and so that an attribute abrupt change region is provided between the adjacent segments by making the adjacent segments have different attributes at least at the contacted portion, each segment can be visually and accurately recognized based on the attribute abrupt change region. Specifically, for convenience of description, as illustrated in fig. 12, the three-dimensional model of fig. 12 includes a portion of lung organ tissue 22, a blood vessel portion 3 and a lesion portion 1, wherein the portion of the lung organ tissue 22 is divided into 4 segments including a segment where the lesion part 1 is located and three segments adjacent to the segment, any two adjacent segments are respectively formed of transparent materials of different colors, i.e., a region of abrupt change in property between any two adjacent segments, while the vessel portion 3 and the lesion portion 1 may be formed of colored opaque material, thus, the blood vessel part 3 and the lesion part 1 in the lung organ tissue 22 can be clearly observed from the outside of the three-dimensional organ model, the lung organ tissue 22 can be divided into a plurality of segments, and a user can intuitively judge the relative position relationship between the lesion part 1 and the blood vessel part 3 and between the segments; in addition, in practical application, it may not be necessary to print the whole organ, and only a part of the organ may be printed to meet the requirement, for example, in the surgical planning, the physician only needs to know which segment of the tissue organ portion 2 the lesion portion 1 is located in, the position of the segment adjacent to the segment, and the positional relationship between the segment and the blood vessel portion 3, that is, the three-dimensional organ model only needs to include the lesion portion 1, the blood vessel portion 3, and the segment of the tissue organ portion 2 including the lesion portion 1 and the segment adjacent to the segment to meet the requirement of the physician, so that the amount of material used for printing the three-dimensional organ model can be reduced to reduce the cost of the three-dimensional organ model.

Since the transparency of the colored transparent material is generally low and the transparency of the printed three-dimensional organ model as a whole is reduced as the printing thickness is increased, in order to improve the transparency of the three-dimensional organ model as a whole so that the user can observe the distribution of the blood vessel portion 3 and the location of the lesion 1 inside the tissue organ portion 2, in the present embodiment, each section of the tissue organ portion 2 further includes an outer shell portion 211 and an inner portion 212, the outer shell portion 211 is wrapped outside at least a part of the inner portion 212, the outer shell portion 211 is formed of a colored transparent material, the inner portion 212 is formed of a colorless transparent material, since the colored transparent material is finally printed to have a thickness of only the outer shell portion 211 and the inner portion 212 is formed of a non-colored transparent material having a transparency greater than that of the colored transparent material, the transparency of the tissue organ portion 2 as a, while the housing portions 211 of two adjacent segments are formed of colored transparent materials of different colors, i.e., any two adjacent segments have an abrupt property change region therebetween to facilitate distinguishing the adjacent segments.

In the present embodiment, fig. 17 shows a schematic flow chart of dividing each segment into the housing part 211 and the inner part 212, specifically, in each segment, the segment is divided into the housing part 211 and the inner part 212 at a position facing a certain distance into the segment in a direction perpendicular to the outer surface of the segment, the housing part 211 is wrapped on the outer side of the whole inner part 212, the thickness of the housing part 211 can be adjusted according to the transparency of the material, and in general, the thickness of the housing part 211 can be 0.05mm-100 mm. Fig. 18 shows another flow diagram for dividing each segment into a housing part 211 and an inner part 212, in particular, in each segment, the segment is divided into a housing part 211 and an inner part 212 at a position facing a distance into the segment in a direction perpendicular to the dividing plane of the segment, and the housing part 211 is wrapped around the outer side of the inner part 212.

Specifically, in this embodiment, a segmented structure of an arterial dissection model is provided, and fig. 13, fig. 14 and fig. 15 show an arterial dissection diagram, where an artery is one of the blood vessel portions 3 in this embodiment, and an arterial dissection is a variant artery, that is, a variant of the blood vessel portion 3, where the arterial blood vessel includes an intima 311, a media 312 and an adventitia, and in a normal arterial blood vessel, the 3 layers of structures are closely attached to each other and together support the passage of blood flow, where the media 312 is the thickest and mainly consists of 40 to 70 layers of elastic membranes with holes, and the arterial dissection refers to a state where blood in an arterial lumen enters the aortic media 312 from a torn part of the aortic intima 311, so that the media 312 and the adventitia separated outer membrane are separated and expanded along the major axis direction of the artery to form a true-false two-lumen separation state of the. In practical application, the blood vessel can be divided into a true lumen segment 31 and a false lumen segment 32 based on the position where the media 312 and the adventitia are separated, the true lumen segment 31 includes the intima 311 and the media 312 of the arterial blood vessel and the true lumen adventitia 313 of the true lumen part, and the false lumen segment 32 includes the false lumen adventitia 321 of the false lumen part; at this time, by making the real lumen segment 31 and the dummy lumen segment 32 have different properties, i.e., making a property abrupt region formed between the real lumen segment 31 and the dummy lumen segment 32, it is possible for the doctor to distinguish the real lumen from the dummy lumen, and further, if the dummy lumen segment 32 is made of a transparent material, it is possible to visually confirm the position of the tear on the inner membrane 311.

As shown in fig. 5, in the present embodiment, for convenience of description, a liver organ tissue 21 is still taken as an example for explanation, and specifically, the printing apparatus includes:

the data acquiring module 6 is configured to acquire image data, where the image data includes two-dimensional image data, three-dimensional image data, and other image data, and the image data is not specifically limited herein as long as the image data that conforms to the three-dimensional organ model printing can be satisfied.

A three-dimensional modeling module 7 for performing three-dimensional modeling based on the image data to obtain a three-dimensional model including at least one of the tissue organ portion 2, the blood vessel portion 3, and the lesion portion 1.

A model segmentation module 8 for segmenting the tissue organ portion 2 and/or the blood vessel portion 3 into a plurality of segments.

A print attribute definition module 9 for defining print attributes for the three-dimensional model such that there is at least one attribute discontinuity between the plurality of segments.

And the printing and forming module 10 is used for printing to obtain the three-dimensional organ model.

As shown in fig. 6, in this embodiment, the data obtaining module 6 may include a data previewing module 61 and an image preprocessing module 62, where the data previewing module 61 is configured to view related contents of data, and the image preprocessing module 62 is configured to determine whether an image is inverted, and adjust the inverted image to a correct direction.

Specifically, in this embodiment, the three-dimensional modeling module 727 includes an extracting module 71, a modeling module 72 and a fusing module 73, wherein the extracting module 71 is configured to extract data of the tissue organ portion 2, data of the blood vessel portion 3 and/or data of the lesion portion 1 from the image data, the modeling module 72 is configured to create a three-dimensional tissue organ model, a three-dimensional blood vessel model and/or a three-dimensional lesion model based on the extracted data, and the fusing module 73 is configured to fuse the three-dimensional lesion model, the three-dimensional tissue organ model and/or the three-dimensional blood vessel model to obtain the three-dimensional model.

As shown in fig. 8, in particular, the model segmentation module 8 comprises a segmentation module 81, the segmentation module 81 is configured to determine a segmentation plane 5 in the tissue organ portion 2 and/or the blood vessel portion 3 for segmenting the tissue organ portion 2 and/or the blood vessel portion 3; the model segmentation module 8 may further include a partition plate establishment module 82, where the partition plate establishment module 82 is configured to form a partition plate 4 having a certain thickness based on the segmentation plane 5 determined by the segmentation module 81, and fuse the partition plate 4 with the three-dimensional model; the model segmentation module 8 may further comprise a segmentation module 83, the segmentation module 83 being configured to segment the segment into an outer part 211 and an inner part 212.

As shown in fig. 9, in particular, the print forming module 10 includes a data processing module 101 and a printing module 102, the data processing module 101 is configured to slice a three-dimensional model with print attributes defined to obtain slice data and obtain print control data based on the slice data, and the printing module 102 is configured to print based on the print control data to obtain a three-dimensional organ model.

In this embodiment, the beneficial effect of the three-dimensional organ model printed by using the printing apparatus is the same as that of the three-dimensional organ model printed by using the printing method for the three-dimensional organ model described in any of the above embodiments, and thus, the foregoing description has been made explicitly, and details are not repeated here.

As shown in fig. 10-15, in the present embodiment, a three-dimensional organ model is further provided, and specifically, the three-dimensional organ model includes at least one of a tissue organ portion 2, a blood vessel portion 3 and a lesion portion 1, the tissue organ portion 2 and/or the blood vessel portion 3 includes a plurality of segments, wherein any two adjacent segments have at least one property mutation region therebetween, and by segmenting the tissue organ portion 2 and/or the blood vessel portion 3 in the three-dimensional organ model and defining at least one property mutation region between any two adjacent segments to distinguish the segments, visual and accurate recognition of the segments of the tissue organ portion 2 and/or the blood vessel portion 3 is achieved. Furthermore, the focus part 1 is combined into the printed three-dimensional organ model, so that communication between doctors and patients can be facilitated, and a doctor can accurately judge the position of the focus part 1, so that an operation path is better planned to reduce operation risks, and the aim of accurate medical treatment is further fulfilled.

Note that, in the present embodiment, for example, when the three-dimensional organ model is used for teaching, the three-dimensional organ model may not include the lesion part 1.

The present embodiment provides a printing apparatus comprising a processor 11 and a memory 12, wherein the memory 12 is configured to store at least one instruction, and the instruction is loaded and executed by the processor 11 to implement the printing method of the three-dimensional organ model described in any one of the above embodiments.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.