阅读说明：本技术 一种含有螺虫乙酯与依维菌素的杀虫组合物 (Insecticidal composition containing spirotetramat and ivermectin ) 是由 罗昌炎 詹姆斯.T.布里斯托 于 2015-12-30 设计创作，主要内容包括：本发明涉及农业领域,具体涉及一种含有螺虫乙酯与依维菌素的杀虫组合物；本发明特别的涉及一种预防或控制有害生物的方法。一种含螺虫乙酯和依维菌素的杀虫组合物,其特征在于,含有活性成分螺虫乙酯和依维菌素,所述螺虫乙酯和依维菌素的重量比为10:1-50:1。将螺虫乙酯和依维菌素组合用于有效预防或控制有害生物,本发明活性化合物的组合控制有害生物的活性大大高于单独的活性化合物性能总和,效果是真正的协同效应。(The invention relates to the field of agriculture, in particular to an insecticidal composition containing spirotetramat and ivermectin; the invention particularly relates to a method of preventing or controlling pests. An insecticidal composition containing spirotetramat and ivermectin is characterized by containing spirotetramat and ivermectin serving as active ingredients, wherein the weight ratio of the spirotetramat to the ivermectin is 10:1-50: 1. The spirotetramat and the ivermectin are combined to be used for effectively preventing or controlling pests, the activity of the combination of the active compounds for controlling the pests is greatly higher than the sum of the performances of the individual active compounds, and the effect is a real synergistic effect.)

1. An insecticidal composition containing spirotetramat and ivermectin is characterized in that the weight ratio of spirotetramat to ivermectin is 10:1-50: 1.

2. The insecticidal composition of claim 1, wherein the weight ratio of spirotetramat to ivermectin is 15:1-40: 1.

3. The insecticidal composition of claim 1, wherein the weight ratio of spirotetramat to ivermectin is 15:1-35: 1.

4. The insecticidal composition of claim 1, wherein the weight ratio of spirotetramat to ivermectin is 15:1 to 30: 1.

5. An insecticidal composition according to claim 1 wherein the weight of spirotetramat and ivermectin together comprise from 5% to 90% by weight of the composition.

6. An insecticidal composition according to claim 1 wherein the weight of spirotetramat and ivermectin together comprise from 10% to 80% by weight of the composition.

7. An insecticidal composition according to claim 1 wherein the weight of spirotetramat and ivermectin together comprise from 10% to 50% by weight of the composition.

8. An insecticidal composition according to claim 1 wherein the weight of spirotetramat and ivermectin together comprise from 10% to 40% by weight of the composition.

9. The insecticidal composition of claim 1, further comprising a surfactant and/or an extender.

10. The insecticidal composition according to claim 1, wherein the formulation is missible oil, suspending agent, seed coating agent, water dispersible granule, wettable powder, suspoemulsion, extruded granule, coated granule, aerosol, emulsion in water, microcapsule suspending agent and ultra-low volume liquid.

11. Use of the pesticidal composition according to claim 1 for preventing or controlling pests.

12. Use of the insecticidal composition according to claim 1 for preventing or controlling insects, acarids.

13. Use of the insecticidal composition according to claim 1 for preventing or controlling pear psyllid, citrus red spider, cotton aphid, bemisia tabaci.

14. A method of preventing or controlling pests by applying the pesticidal composition of claim 1 to a target useful plant, a target pest or its environment, propagation material of a target useful plant.

15. The method of claim 14, wherein the pest is psyllid, citrus red spider, cotton aphid, bemisia tabaci.

16. A method of protecting crops from pest attack comprising contacting a crop with the pesticidal composition of claim 1.

Technical Field

The invention relates to the field of agriculture, in particular to an insecticidal composition containing spirotetramat and ivermectin; the invention particularly relates to a method of preventing or controlling pests.

Background

Chemical control is an important means of preventing and controlling pests in agriculture. However, at present, it is sometimes impossible to effectively control pests due to the type of pests, the living characteristics, the living environment, and the like, which are poor in effect and developed in resistance.

Ivermectin (Ivermectin) is a novel antibiotic medicament with low toxicity, high efficiency and broad spectrum, and is one of the structural modification products of avermectin. The pure ivermectin is off-white powder, is insoluble in water, and is easily soluble in organic solvents such as methanol, ethanol, acetone, ethyl acetate and the like. The ivermectin also has good control effect on agricultural pests and mites. At present, ivermectin is mainly used for preventing and treating livestock parasites and is less applied in agriculture. Therefore, the ivermectin has wide prospect as a pesticide.

Spirotetramat (Spirotetramat) is a quaternary ketone compound developed by Bayer company, and belongs to the same class of compounds as Spirodiclofen (Spirodiclofen) and Spiromesifen (Spiromesifen), which are insecticidal and acaricidal agents of Bayer company. Spirotetramat has unique action characteristics and is one of modern insecticides with bidirectional systemic conduction performance. The compound can move upwards and downwards in the whole plant body to reach leaf surfaces and barks, so that pests on leaves of lettuce and Chinese cabbage and fruit tree barks can be prevented. This unique systemic property protects the nascent stems, leaves and roots from the growth of pest eggs and larvae. It has another characteristic of long lasting period, and can provide effective control for up to 8 weeks. The structural formula is as follows:

spirotetramat is disclosed in WO 98/05638.

The activity of the individual compounds is good; however, they do not always meet the high requirements which must be met by insecticides, acaricides or nematicides at low application rates or when used against individual pests.

Disclosure of Invention

The present invention aims to solve at least one of the above problems or at least one aspect thereof, and in particular to effectively control pests, the present inventors have unexpectedly found that spirotetramat and ivermectin can be used in combination for effectively preventing or controlling pests, as screened by a number of biological tests. Surprisingly, the activity of the combinations of active compounds according to the invention in controlling pests is considerably higher than the sum of the properties of the active compounds alone. This unexpected effect is a true synergistic effect, not just a complementary effect.

Therefore, the invention aims to provide an insecticidal composition containing spirotetramat and ivermectin and application thereof.

An insecticidal composition containing spirotetramat and ivermectin is realized by adopting the following technical scheme:

an insecticidal composition containing spirotetramat and ivermectin comprises active ingredients of spirotetramat and ivermectin, wherein the weight ratio of the spirotetramat to the ivermectin is 10:1-100: 1.

An insecticidal composition containing spirotetramat and ivermectin, wherein the weight ratio of spirotetramat to ivermectin is 10:1-90: 1.

An insecticidal composition containing spirotetramat and ivermectin, wherein the weight ratio of spirotetramat to ivermectin is 15:1-80: 1.

An insecticidal composition containing spirotetramat and ivermectin, wherein the weight ratio of spirotetramat to ivermectin is 15:1-70: 1.

An insecticidal composition containing spirotetramat and ivermectin, wherein the weight ratio of spirotetramat to ivermectin is 15:1-60: 1.

An insecticidal composition containing spirotetramat and ivermectin, wherein the weight ratio of spirotetramat to ivermectin is 15:1-50: 1.

An insecticidal composition containing spirotetramat and ivermectin, wherein the weight ratio of spirotetramat to ivermectin is 15:1-40: 1.

An insecticidal composition containing spirotetramat and ivermectin, wherein the weight ratio of spirotetramat to ivermectin is 15:1-35: 1.

An insecticidal composition containing spirotetramat and ivermectin, wherein the weight ratio of spirotetramat to ivermectin is 15:1-30: 1.

An insecticidal composition containing spirotetramat and ivermectin, wherein the weight ratio of spirotetramat to ivermectin can be 10:1, 12:1, 14:1, 15:1, 16:1, 18:1, 20:1, 21:1, 22:1, 23:1, 24:1, 25:1, 26:1, 27:1,28:1, 29:1, 30:1, 32:1, 34:1, 36:1, 38:1, 40:1, 45:1, 50:1, 55:1, 60:1, 65:1,70:1, 75:1,80:1, 85:1, 90:1,95:1 and 100: 1.

An insecticidal composition containing spirotetramat and ivermectin is characterized in that the weight of the spirotetramat and the ivermectin accounts for 5% -90% of the composition by weight.

An insecticidal composition containing spirotetramat and ivermectin is characterized in that the spirotetramat and the ivermectin account for 10-80% of the composition by weight in total.

An insecticidal composition containing spirotetramat and ivermectin is characterized in that the spirotetramat and the ivermectin account for 10-50% of the composition by weight in total.

An insecticidal composition containing spirotetramat and ivermectin is characterized in that the spirotetramat and the ivermectin account for 10-40% of the composition by weight in total.

An insecticidal composition containing spirotetramat and ivermectin is characterized in that the spirotetramat and the ivermectin account for 10-30% of the composition by weight in total.

The insecticidal composition containing the spirotetramat and the ivermectin further comprises a surfactant and/or an extender.

The pesticide composition of the spirotetramat and the ivermectin is in the dosage forms of missible oil, suspending agent, seed coating agent, water dispersible granule, wettable powder, suspoemulsion, extruded granule, coated granule, aerosol, emulsion in water, microcapsule suspending agent and ultra-low volume liquid.

An insecticidal composition comprising spirotetramat and ivermectin, wherein the composition further comprises one or more other active ingredients.

In another aspect, the invention also provides the use of the pesticide insecticidal composition containing the spirotetramat and the ivermectin for preventing or controlling pests, wherein the pests are insects and mites.

In another aspect, the present invention also provides a method of preventing or controlling pests by applying an insecticidal composition comprising spirotetramat and ivermectin to a target useful plant, a target pest or its environment, propagation material of a target useful plant; the plant propagation material is a seedling, a rhizome, a nursery seedling, a cutting or a seed; the weight ratio of the spirotetramat to the ivermectin is 10:1-100: 1.

A method of protecting crops from pest attack comprising contacting a crop with an insecticidal composition comprising spirotetramat and ivermectin.

A method of preventing or controlling pests comprising the separate, sequential or simultaneous application of spirotetramat, ivermectin.

The invention also provides a method for preventing or controlling pests, which comprises the step of acting the insecticidal composition containing the spirotetramat and the ivermectin on target useful plants, target pests or environments thereof and propagation materials of the target useful plants; the plant propagation material is a seedling, a rhizome, a nursery seedling, a cutting or a seed; the pest is especially preferably Piprix chinensis, and Aranea mandarinia.

Detailed Description

Unless otherwise indicated, the proportions referred to herein are by weight and the amounts referred to herein are by weight.

The invention discovers that: the combination of spirotetramat and ivermectin not only results in an additive improvement in the insecticidal spectrum, but also achieves a surprising synergistic effect.

The term "synergistic" as used herein means that the pesticidal effect of the active agent combination or composition of the present invention is greater than the sum of the effects of the individual active agents, or that its effect is superadditive.

The invention provides an insecticidal composition containing spirotetramat and ivermectin, wherein the weight ratio of spirotetramat to ivermectin is 10:1-100:1, preferably 10:1-90:1, 15:1-80:1, 15:1-70:1,15:1-60:1,15:1-50:1,15:1-40:1,15:1-35:1, and 15:1-30: 1.

The weight ratio of the spirotetramat to the ivermectin can also be 10:1, 12:1, 14:1, 16:1, 18:1, 20:1, 21:1, 22:1, 23:1, 24:1, 25:1, 26:1, 27:1,28:1, 29:1, 30:1, 32:1, 34:1, 36:1, 38:1, 40:1, 45:1, 50:1, 55:1, 60:1, 65:1,70:1, 75:1,80:1, 85:1, 90:1,95:1 and 100: 1.

The total amount of active ingredient compounds in the pesticidal composition of the present invention may be selected according to specific factors to achieve the desired effect. Such as dosage form, subject to be administered, method of administration, and the like. The spirotetramat and the ivermectin together constitute from 5% to 90%, preferably from 10% to 80%, more preferably from 10% to 50% by weight of the composition.

The spirotetramat and ivermectin may also be present in total in 5%, 8%, 10%, 12%, 15%, 18%, 20%, 20.8%, 22%, 25%, 28%, 30%, 32%, 35%, 38%, 40%, 42%, 45%, 48%, 50%, 52%, 55%, 58%, 60%, 62%, 65%, 68%, 70%, 72%, 75%, 78%, 80%, 82%, 85%, 88%, 90% of the pesticidal composition.

The compositions of the present invention may optionally comprise an agronomically acceptable surfactant and/or extender.

According to the present invention, the term "filler" refers to a natural or synthetic organic or inorganic compound that can be combined or associated with an active compound to make it easier to apply to a subject (e.g. plants, crops or grasses). Thus, the carrier is preferably inert, at least should be agronomically acceptable. The filler may be solid or liquid.

The inactive filler that can be used in the present invention may be either solid or liquid, and examples of the solid filler include: examples of the inorganic filler include vegetable powders (for example, particles of soybean powder, starch, cereal powder, wood powder, bark powder, saw dust, walnut shell powder, bran, cellulose powder, coconut shell, corn cob, and tobacco stalk, and residues after extraction of plant essence), paper, saw dust, synthetic polymers such as ground synthetic resins, clays (for example, kaolin, bentonite, and acid china clay), and talc powders. Silica (for example, diatomaceous earth, silica sand, mica, hydrous silicic acid, calcium silicate), activated carbon, natural minerals (for example, pumice, attapulgite, zeolite, etc.), calcined diatomaceous earth, sand, plastic media (for example, polyethylene, polypropylene, polyvinylidene chloride, etc.), inorganic mineral powders such as potassium chloride, calcium carbonate, calcium phosphate, etc., chemical fertilizers such as ammonium sulfate, ammonium phosphate, urea, ammonium chloride, etc., and soil fertilizers, and these may be used alone or in combination of 2 or more.

Examples of the liquid filler that can be used include water, alcohols (e.g., methanol, ethanol, isopropanol, butanol, ethylene glycol, etc.), ketones (e.g., acetone, methyl ethyl ketone, diisobutyl ketone, cyclohexanone, etc.), ethers (e.g., diethyl ether, dioxane, methyl cellulose, tetrahydrofuran, etc.), aliphatic hydrocarbons (e.g., kerosene, mineral oil, etc.), aromatic hydrocarbons (e.g., benzene, toluene, xylene, mineral spirits, alkyl naphthalenes, chlorinated aromatic hydrocarbons, chlorinated aliphatic hydrocarbons, chlorobenzene, etc.), halogenated hydrocarbons, amides, sulfones, dimethyl sulfoxide, mineral and vegetable oils, animal oils, etc.

Examples of the surfactant that can be used for emulsifying, dispersing, solubilizing, and/or wetting the active ingredient compound include fatty alcohol polyoxyethylene ethers, polyoxyethylene alkylaryl ethers, polyoxyethylene higher fatty acid esters, phosphoric acid esters of polyoxyethylene alcohols or phenols, fatty acid esters of polyhydric alcohols, naphthalenesulfonic acid polymers, lignosulfonates, branched copolymers of high molecular comb-like polymers, butylnaphthalenesulfonates, alkylarylsulfonates, sodium alkylsulfosuccinates, fats and oils, condensates of fatty alcohols with ethylene oxide, polyacrylates of alkyltaurates, and protein hydrolysates. Suitable oligosaccharides or polymers are based, for example, on ethylene monomers, acrylic acid, polyoxyethylene and/or polyoxypropylene alone or in combination with, for example, (poly) alcohols or (poly) amines.

For dispersing, stabilizing and adhering the active ingredient compounds, auxiliary agents such as xanthan gum, magnesium aluminum silicate, gelatin, starch, cellulose methyl ether, polyvinyl alcohol, polyvinyl acetate, natural phospholipids (such as cephalin and lecithin), synthetic phospholipids, bentonite, sodium lignin sulfonate and the like can be used.

Wherein the antifreezing agent can be selected from ethylene glycol, propylene glycol, glycerol, and sorbitol. As the deflocculant for the suspendable product, an auxiliary such as a naphthalenesulfonic acid polymer, a polymeric phosphate, or the like can be used. As the defoaming agent, a silicone defoaming agent can be used. In order to improve the flowability of the solid product, auxiliaries such as paraffin, stearate, alkyl phosphate and the like can be used.

Colorants which may be used, for example, inorganic pigments such as iron oxide, titanium oxide and prussian blue; and organic pigments/dyes: alizarin dyes, azo dyes, and metal phthalocyanine dyes; and trace elements such as iron, manganese, boron, copper, cobalt, molybdenum and zinc salts.

Optionally, further additional components, such as protective colloids, binders, thickeners, thixotropic agents, penetrating agents, stabilizers, masking agents, can also be included.

The dosage form of the insecticidal composition containing spirotetramat and ivermectin is as follows: aerosols, suspensions, microencapsulated granules, fine granules, flowable concentrates, ready-to-use solutions, powders, aqueous emulsions, oil emulsions, microgranules, oil-dispersible powders, oil-miscible flowable concentrates, oil-miscible liquids, foams, pastes, suspension concentrates, suspoemulsions, soluble concentrates, soluble powders, granules, water-soluble granules and/or tablets, water-soluble powders, wettable powders, natural or synthetic materials impregnated with active compounds, microcapsules in polymeric materials and water-dispersible granules.

In a preferred embodiment, the insecticidal composition is a suspending agent, a water dispersible granule, a wettable powder, a suspending emulsion, an emulsifiable concentrate, a seed coating agent, a wettable powder, an extruded granule, a coated granule, an aerosol, an emulsion in water, a microcapsule suspending agent.

The formulations of the invention can be prepared by mixing the active compounds with the customary additives in a known manner. Such as conventional extenders as well as solvents or diluents, emulsifiers, dispersants, and/or binders or fixatives, wetting agents, water repellents, if desired siccatives and colorants, stabilizers, pigments, defoamers, preservatives, thickeners, water and other processing aids.

These compositions include not only those which are immediately applicable to the subject to be treated by means of a suitable device, such as a spraying or dusting device, but also concentrated commercial compositions which are intended to be diluted prior to application to the subject.

The insecticidal composition of the present invention can be prepared into a formulation suitable for application in the form of a combination of its active ingredient compounds, or can be applied in the form of a combination of commercial formulations in appropriate dosages.

The pesticidal composition of the present invention may also be applied in combination with other active ingredients such as fungicides, bactericides, attractants, insecticides, acaricides, nematicides, growth regulators, herbicides, safeners, fertilizers or semiochemicals and the like.

The insecticidal composition containing the spirotetramat and the ivermectin has good plant compatibility and favorable constant-temperature animal toxicity, and is suitable for controlling pests, preferably arthropods and nematodes, especially insects and mites, encountered in agriculture, forestry, storage product and material protection and sanitation fields. They are active against normally sensitive and resistant species and active against all or a single developmental stage.

The term "pest" as used herein means any organism that can cause loss of the normal state of a plant. "pests" may include lepidoptera, diptera, coleoptera, hemiptera, homoptera, orthoptera, hymenoptera, isoptera, siphonaptera, blattaria, thysanoptera, mites and the like.

Lepidopteran pests include, for example: chilo suppressalis (chilopodes) (walker), tryporyza incertulas (walker), ostrinia nubilalis (ostrinia nubilalis), ostrinia nubilalis (pachilioxustifolia), phaeriana leucoptera (Pierilispora), Orthosiphon aristatus (paraguatta), Trichophyta (paraguata), Trichosta (miraculina tetragonoides), Lymantria dispar (Lymantria dispar), Hypoglossa cunea (Lymantria dispar), Hypoglossa (Lymantria dispar), Ostrinia dispar (Lymantria dispar), Hypoglossa (Lymantria cunea), Ostrinia orientalis), Ostrinia (Euonyx striata), Spodoptera (Spodopteria litura), Spodopteria litura (Spodopteria litura), Spodopteria (Spodopteria litura), Spodoptera (Spodopteria litura), Spodoptera (Spodoptera), Spodoptera (Spodoptera frugiperla), Spodoptera (Spodoptera).

Coleopteran pests include, for example: rice elephants (sinophilius oryzae eines), corn elephants (s. zeamais), grain elephants (s. granaria), gibbon ape beetles (cabbagageleaf beetles), ape leaf beetles (Daikon leaf beetles), flea beetles (flambette), grape flea beetles (altiachalybla), curly striped flea beetles (phyllotritala), cucumber flea beetles (epixcucuumeris), tobacco flea beetles (ehirtiphennis), eggplant flea beetles (e.fuscula), yellow datura (aulachorandica (gemlin), mustard leaf beetles (Phaedon cochleariae), and the like.

Dipteran pests include, for example: rice plant fly (agromozaoryza), barley water fly (hydralligriseola), gerbera camomilla (liriomyzatrifolii), pea leaf fly (chromoniahorticola), tomato leaf fly (liriomyzabryoniae), gray fly (delactatura), green onion fly (delavata) mediterranean fly (ceratitis capitata wiedman), apple fly (rhagoletisponella), cherry fly (r.

Hemipteran pests include, for example: stinkbug (megatiptatticimum), corium elephatis (eurydemasum), stinkbug (eusartorius major), stinkbug (eusarcocylilissis), stinkbug (eusarcocorisparvus), stinkbug (nezaraviridula), stinkbug (platistali), stinkbug (halirphista), stinkbug (clethostachydigitalis), stinkbug (clethostus punctiger), stinkbug (lygus lucentis), stinkbug (leptospiensis), stinkbug (sterrisitis), and stinkbug (gonotylupestium).

Homopteran pests include, for example, the leafhopper (nonphyttixcinceps), the laodelphax striatellus (laodelphaxstratella), the brown planthopper (nilaparvatalens), the sogatella furcifera (sogatella furcifera), the psylla pyricularis (psyllicularia), the diaphorina citri (diaphorinatabaaci), the bemisia tabaci (bemisia), the aphid (homoptera), the aphis malus (erioglaciarius).

Examples of hymenoptera (hymenoptera) include Ouioia flavedo (athaliaria palmiformis), Ouia rosepalae (Argepagana), Formica japonica (Formica japonica), and Ouia castellata (dryocsumura) and the like.

Pests of the order Thysanoptera, e.g. thrips (Haplothrips Chinensis Presener)

Pests of the Arachnida (Arachnida). For example, Panonychus citri (pannyhus citri), Panonychus ulmi (pannyhus ulmi), Tetranychus urticae (Tetranyhus urticae), Tetranychus urticae (Tetranyhus virens), Tetranychus urticae (Tetranychus urticae), Tetranychus urticae (oligochychus unguensis), Tetranychus citrullus (eotarychus unshiu), Brevipemaphycus purpureus (Brevipus Phoenis), Bryobia carnosus (Bryobia purpureus), Tetranychus tritici (Aeria ciliopa), Vitis vinifera (virosus vitis), Camellia sinensis (Lacarurus carinatus), Phaneratidae (Pharmatophus larsus latus), Rhizopus elongatus (Rhizophus striatus stockensis), and the like.

From the order of the Anoplura, Phthiraptera, for example, the animal louse (Damalinia spp.).

The genera Haematopinus (Haematopinus spp.), pediculosis (Linogathus spp.), and pediculosis

(Pediculus spp.), Pediculus (Trichodectes spp.).

Isopoda (Isopoda), for example, Gardenia jasminoides Ellis (Oniscus asellus), Armadillium vulgare (Armadillidium vulgare), Armadillidium globosum (Porcellio scaber).

From the order of the Diplopoda (Diplopoda), for example, Blaniulus guttulatus.

From the order of the Chilopoda (Chilopoda), e.g. Geophilus carpopophagus

Scutigera spp.) 。

The synthetic mesh (Symphyla), for example, white pine worm (Scutigerella immaculata).

From the order of the Thysanura, for example, Chlamydomonas (Lepisma saccharana).

From the order of the Collelmola (Collelmbola), for example, Onychiurus armatus (Onychiurus armatus).

From the order of the Orthoptera (Orthoptera), e.g., cricket (Acheta domesticus), Phillips

Genus species (Gryllotalpa spp.), Locusta migratoria (Locusta migratoria), Locusta species (melanoplus pp.), desert Locusta (schistoserccagregaria).

From the order of the Blattaria (Blattaria), for example, Blatta orientalis (Blatta orientalis), Periplaneta americana (Periplaneta americana), Blatta maderae (Leucophaea maderae), Blattella germanica (Blattegera).

From the Dermaptera (Dermaptera), for example, Forficula auricularia (Forficula auricularia).

From the order of the Isoptera (isoptera), for example, the Reticulitermes spp.

Representative organisms of the class Nematoda (Nematoda) are nematodes selected from the group consisting of root-knot nematodes, cyst-forming nematodes, stalk nematodes and leaf nematodes. Preferred are soybean cyst nematodes (Heterodera), potato nematodes (golbdostostonis), meloidogyne incognita (meloidogyne incognita), etc., among the orders of the spearling (dorylaimida), and the species strongyloides (longidrus sp.), etc.

All plants and plant parts can be treated according to the invention. Plants in this context are to be understood as meaning all plants and plant populations, such as desired and undesired wild plants or crop plants (including naturally occurring crop plants). Crop plants are plants which can be obtained by conventional breeding and optimization methods or by biotechnological and genetic engineering methods or by combinations of these methods, including the transgenic plants, also including the plant varieties which can be protected or not protected by plant breeders' rights. Plant parts are to be understood as meaning all parts and organs of the plant above and below the ground, such as shoots, leaves, flowers and roots, examples which may be mentioned being leaves, needles, leaves, stems, flowers, fruit bodies, fruits and seeds, and also roots, tubers and rhizomes. The plant parts also include harvests and vegetative and generative propagation material, such as cuttings, tubers, rhizomes, shoots and seeds.

Plants suitable for the pesticidal composition of the present invention include:

crops: corn, rice, wheat, barley, rye, oat, sorghum, cotton, soybean, adzuki bean, kidney bean, peanut, buckwheat, beet, rape, sunflower, sugarcane, tobacco, etc.;

vegetable: solanum vegetables (eggplant, tomato, red bell pepper, zanthoxylum, potato, etc.), cucurbits (cucumber, pumpkin, zucchini, watermelon, wax gourd, pumpkin, etc.), crucifers (japanese radish, white radish, horseradish, kohlrabi, chinese cabbage, mustard, broccoli, cauliflower, etc.), asteraceae vegetables (burdock, garland chrysanthemum, jerusalem artichoke, lettuce, etc.), liliaceae vegetables (welsh onion, garlic, and asparagus), ammiaceous vegetables (carrot, caraway, celery, parsnip, etc.), chenopodiaceae vegetables (spinach, swiss chard, etc.), menthaceae vegetables (perilla frutescens, mint, basil, etc.), strawberry, sweet potato, wild yam, taro, etc.;

and (3) flowers: roses, dianthus chinensis, chrysanthemum, tulip, gentian, orchid and the like;

foliage plants;

turfgrass;

fruit trees: pome fruits (apple, avocado, japanese pear, chinese quince, etc.), stone-fruit fruits (peach, plum, nectarine, japanese plum, cherry, apricot, prune, etc.), citrus fruits (satsuma mandarin, orange, lemon, lime, grapefruit, etc.), nuts (chestnut, walnut, hazelnut, almond, pistachio, cashew nut, macadamia nut, etc.), berry fruits (blueberry, raspberry, blackberry, brambleberry, etc.), grape, persimmon, olive, plum, banana, coffee, date palm, coconut, etc.;

trees other than fruit trees: tea, mulberry, flowering tree, street tree (locust tree, birch, dogwood, eucalyptus, ginkgo, lilac, maple, oak, poplar, cercis, sweetgum, sycamore, juniper, pine, spruce, and taxus cuspidata), and the like.

It is emphasized that the insecticidal compositions of the invention have particularly advantageous effects when used, for example, in the following plants: cereals such as wheat, oats, barley, spelt, triticale and rye, but also maize, sorghum and chestnut, rice, sugarcane, soybean, sunflower, potato, cotton, oilseed rape (rape), canola (canola), tobacco, sugar beet, fodder beet, asparagus, hop and fruit plants (including pome, such as apple and pear, stone fruit, such as peach, cherry, plum, apricot, citrus fruits, such as orange, grape, lime, pistachio, kumquat, citrus and samomo mandarin, nuts, such as avocado, almond, walnut and pecan, tropical fruits, such as mango, papaya, pineapple, date and banana, and grapes) and vegetables (including leafy vegetables, such as endive, fennel, leafy lettuce, upright lettuce, swiss beet, spinach and salad broccoli, such as broccoli, chicory, lettuce, flowers, rice, sugar cane, soybean, sunflower, potato, tomato, rape (canola, rape, black wheat, rye, black wheat and rye, Broccoli, lettuce leaves, Brassica oleracea (l.) convar. acephala. sabellica l. (savoy cabbage, kale), kohlrabi, brussel sprouts, red cabbage, white cabbage and savoy cabbage, fruit vegetables such as eggplant, cucumber, pepper, edible squash, tomato, zucchini and sweet corn, root vegetables such as tuberous celery, rape, carrots including yellow varieties, wild radishes including Raphanus sativus var.

The treatment of plants and plant parts with the insecticidal compositions according to the invention is carried out directly or by treating their environment, habitat or storage space by conventional treatment methods, such as dipping, spraying, evaporation, fogging, scattering, painting on, and also coating the propagation material, in particular the seeds, with one or more layers.

The wetting of the locus of the plant with the liquid composition, or the treatment of the target useful organisms with the composition of the invention in solid form, can be carried out directly or by acting on its environment, habitat or storage area by customary treatment methods, such as application to the foliage of the plant by watering (immersion), drip irrigation, spraying, evaporation, fogging, scattering, dusting, foaming, coating or the like (foliar application), the frequency and amount of application being adjusted to the extent of attack by the pests.

The active ingredient is incorporated into the locus of the plant, for example in the form of granules (soil application), or it can enter the interior of the plant via the root system (systemic action). The soil or culture medium of the plant used in the practice of the method of the present invention is a support capable of rooting and growing a crop, and includes, for example: examples of the raw material include sand, pumice, vermiculite, diatomaceous earth, agar, gel, polymer, asbestos, wood chips, and bark.

Examples of methods for applying a chemical to soil include a method in which a liquid chemical is diluted in water or applied without dilution directly to the roots of a plant or a seedling bed for raising seedlings, a method in which granules are sown to the roots of a plant or a seedling bed for raising seedlings by spraying a powder, a water dispersible granule or the like to soil and mixing with the whole soil before sowing, and a method in which a powder, a water dispersible granule or the like is diluted and sprayed to a planting hole or a planting furrow before sowing or planting a plant, and sowing is performed.

The insecticidal compositions of the invention are also suitable for protecting propagation material of plants, such as seeds, fruits, tubers or kernels, or plant cuttings, against pests, in particular insects and mites. The propagation material may be treated with the composition before application, for example dressing the seed before sowing. The active ingredient may also be applied to the kernel (coating) by soaking the kernel in a liquid composition or coating the kernel with a solid composition. The composition may also be applied to the application site when the propagation material is applied during sowing, for example in a seed sowing trench. These methods of treatment of plant propagation material and the plant propagation material so treated are further subjects of the present invention.

Most of the damage caused by pests to crop plants occurs as early as when the seeds are infested, during storage and after the seeds are sown into the soil and during or after germination of the plants. This stage is particularly critical because the roots and shoots of growing plants are particularly sensitive, and even minor damage can lead to death of the entire plant. Therefore, the protection of seeds and germinating plants by using suitable compositions is of particular interest.

The control of pests by treating plant seeds has long been known and is the subject of constant improvement. However, treating seeds also entails a series of problems that cannot always be solved in a satisfactory manner. Therefore, there is a need to develop methods for protecting seeds and germinating plants which avoid the additional application of crop protection products after planting or after emergence of the plants. In addition, there is a need to optimize the amount of active compound used so that optimum protection is provided to the seed and the germinating plant against attack by pests without the active compound used damaging the plant itself. In particular, the method of treating seeds may also take into account the inherent insecticidal properties of the transgenic plants to achieve optimal protection of the seeds and the germinating plants with minimal crop protection products.

The present invention therefore also relates in particular to a method for protecting seeds and germinating plants from attack by pests by treating the seeds with the pesticidal compositions according to the invention. The method of the present invention for protecting seeds and germinating plants from pest attack comprises a method of treating said seeds simultaneously with spirotetramat and ivermectin. It also includes a method of treating the seed with spirotetramat and ivermectin at different times. The invention also relates to the use of the pesticidal composition of the invention for treating seeds to protect said seeds and plants grown therefrom from attack by pests. Furthermore, the present invention relates to seeds treated with the pesticidal composition of the present invention to obtain protection from pests. The invention also relates to the seed treated by the spirotetramat and the ivermectin simultaneously. The invention also relates to seeds treated with spirotetramat and ivermectin at different times. For seeds treated with spirotetramat and ivermectin at different times, the individual active compounds of the pesticidal composition of the present invention may be present in different layers on the seed. Wherein the layers comprising spirotetramat and ivermectin are optionally separated by an intermediate layer. The invention also relates to seeds wherein spirotetramat and ivermectin are applied as coating components or as one or more additional layers outside the coating.

One of the advantages of the present invention is the special systemic properties of the active compound combinations according to the invention, i.e. the treatment of the seeds with the insecticidal compositions according to the invention protects not only the seeds themselves but also the plants obtained after germination from pests. In this way, it is possible to dispense with the immediate treatment of the crop at the time of sowing or later.

A further advantage is the synergistically increased insecticidal activity of the active compound combinations according to the invention compared with the respective active compound alone, which insecticidal activity exceeds the sum of the activities of the two active compounds on application of each other. This makes it possible to optimize the amount of active compound used.

On the other hand, the treatment of the invention can also produce the following superadditive effect: improving plant growth, increasing tolerance to high or low temperatures, increasing tolerance to drought or to water or soil salt content, increasing flowering performance, making harvesting simpler, accelerating maturation, increasing harvest yield, improving the quality and/or nutritional value of the harvested product, improving the storage stability and/or processability of the harvested product.

It is common and advantageous for the pesticidal compositions of the present invention to be applied generally at the following dosages:

-for leaf treatment: 0.1 to 10000 g/ha, preferably 10 to 1000 g/ha, more preferably 20 to 300 g/ha; for dipping or instillation administration, the dosage may even be reduced, particularly when an inert substrate such as asbestos or perlite is applied;

-for seed treatment: 2-200g per 100kg of seeds, preferably 3-150g per 100kg of seeds;

-for soil treatment: 0.1 to 10000 g/ha, preferably 1 to 5000 g/ha.

The above-mentioned dosages are only typical exemplary dosages, and the application rates will be adjusted by the person skilled in the art in the actual application according to the actual circumstances and needs, in particular according to the nature of the plants or crops to be treated and the conditions of the pests.

It should be noted that in the sense of the present invention, the term "pesticidal composition of spirotetramat and ivermectin" includes separate, sequential or simultaneous application of spirotetramat and ivermectin. Preferably, the insecticidal composition of spirotetramat and ivermectin is in the form of a composition comprising spirotetramat and ivermectin.

The pesticidal composition according to the present invention may be provided in the form of a finished formulation, i.e. the substances in the composition have been mixed; it can also be provided as a single dose formulation, mixed directly in a tub (can) prior to use. The concentrates of the invention are typically mixed with water to give the desired concentration of active.

The beneficial effects of the invention are as follows:

(1) after the two are compounded, the synergistic effect is obvious compared with a single agent, and the insecticidal effect is improved;

(2) after the two are compounded, the action mechanisms and the action modes of the two are completely different, the two have good killing effect on the young and the old larvae after being combined, the action sites are increased, and the generation of drug resistance of pests is favorably overcome and delayed;

(3) after the two are compounded, the medicine taking times are reduced, the medicine taking cost is reduced, and the environmental pollution and the pesticide residue are reduced; in addition, the control spectrum of pests is increased to a certain extent.

(4) The insecticidal composition has special control effect on pear psylla, citrus red spider, cotton aphid and bemisia tabaci.

Detailed Description

The present invention is further illustrated by the following examples, which are not intended to limit the invention to these embodiments. It will be appreciated by those skilled in the art that the present invention encompasses all alternatives, modifications and equivalents as may be included within the scope of the claims.

Unless otherwise indicated, the proportions referred to herein are by weight and the amounts referred to herein are by weight.

Preparation example