阅读说明：本技术 一种治疗阳痿早泄的中药组合物及其制备方法和应用 (Traditional Chinese medicine composition for treating impotence and premature ejaculation and preparation method and application thereof ) 是由 邢乐 于 2019-11-04 设计创作，主要内容包括：本发明公开了一种治疗阳痿早泄的中药组合物,所述中药组合物的组分及各组分的质量份数如下：淫羊藿95～105份,巴戟天95～105份,花椒95～105份,栀子95～105份,淮续断95～105份,牛膝195～205份,羌活95～105份以及艾草115～125份。同时,本发明公开了一种治疗阳痿早泄的中药组合物的制备方法。本发明还公开了一种治疗阳痿早泄的中药组合物用于制备泡脚液的应用。(The invention discloses a traditional Chinese medicine composition for treating impotence and premature ejaculation, which comprises the following components in parts by mass: 95-105 parts of epimedium, 95-105 parts of morinda officinalis, 95-105 parts of pepper, 95-105 parts of gardenia, 95-105 parts of teasel root, 195-205 parts of achyranthes bidentata, 95-105 parts of notopterygium root and 115-125 parts of wormwood. Meanwhile, the invention discloses a preparation method of the traditional Chinese medicine composition for treating impotence and premature ejaculation. The invention also discloses application of the traditional Chinese medicine composition for treating impotence and premature ejaculation in preparing foot bath liquid.)

1. The traditional Chinese medicine composition for treating impotence and premature ejaculation is characterized by comprising the following components in parts by mass:

95-105 parts of epimedium, 95-105 parts of morinda officinalis, 95-105 parts of pepper, 95-105 parts of gardenia, 95-105 parts of teasel root, 195-205 parts of achyranthes bidentata, 95-105 parts of notopterygium root and 115-125 parts of wormwood.

2. The traditional Chinese medicine composition for treating impotence and premature ejaculation as claimed in claim 1, wherein the traditional Chinese medicine composition comprises the following components in parts by weight:

100 parts of epimedium, 100 parts of morinda officinalis, 100 parts of pepper, 100 parts of gardenia, 100 parts of teasel root, 200 parts of achyranthes root, 100 parts of notopterygium root and 120 parts of wormwood.

3. A method for preparing a traditional Chinese medicine composition for treating impotence and premature ejaculation, which is used for preparing the traditional Chinese medicine composition of any one of claims 1 to 2, and is characterized by comprising the following steps:

step one, weighing component medicinal materials such as epimedium, morinda officinalis, pepper, gardenia, teasel root, achyranthes, notopterygium root and wormwood according to parts by weight, and processing the component medicinal materials into powder;

step two, adding water to the powdery material for multiple times for extraction, filtering, and combining to obtain an extracting solution;

step three, concentrating the extracting solution into extract;

and step four, adding auxiliary materials into the extract to prepare a gel or an oral preparation.

4. The method for preparing a Chinese medicinal composition for treating impotence and premature ejaculation as claimed in claim 3, wherein in the step one, the method for processing the component medicinal materials into powder comprises:

and putting the component medicinal materials into a grinder to be ground into powder, and sieving the powder through a 100-mesh sieve to obtain the powdery material.

5. The method for preparing a Chinese medicinal composition for treating impotence and premature ejaculation as claimed in claim 3 or 4, wherein in the second step, water extraction is performed twice;

wherein, 10 times of water is added into the powdery material for the first time to be decocted for 2 hours; adding 6 times of water into the residue for decocting for 1 hr.

6. The method for preparing a Chinese medicinal composition for treating impotence and premature ejaculation as claimed in claim 5, wherein in the third step, the density ratio of the extract to the extracting solution is 1.2: 1.

7. The method for preparing a Chinese medicinal composition for treating impotence and premature ejaculation as claimed in claim 6, wherein the oral dosage form is: tablet, capsule, microcapsule, granule, pill, powder, oral liquid, dripping pill, sustained release preparation or controlled release preparation.

8. The method for preparing a Chinese medicinal composition for treating impotence and premature ejaculation as claimed in claim 7, wherein the adjuvants added in the preparation of oral dosage form are: one or more of diluent, disintegrant, excipient, binder, lubricant, surfactant, filler, preservative, stabilizer, flavoring agent, thickener and cosolvent.

9. The method for preparing a Chinese medicinal composition for treating impotence and premature ejaculation as claimed in claim 8, wherein the adjuvants added for preparing the gel comprise: carbomer, diethanolamine, and sodium benzoate.

10. The application of the traditional Chinese medicine composition for treating impotence and premature ejaculation, which is prepared by the preparation method of the traditional Chinese medicine composition for treating impotence and premature ejaculation as claimed in any one of claims 3, 4, 5, 6 or 9, is characterized in that the traditional Chinese medicine composition in the form of gel is added into water for dissolving to obtain foot bath liquid.

Technical Field

The invention belongs to the field of preparation of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating impotence and premature ejaculation, and a preparation method and application thereof.

Background

Impotence (ED), Premature Ejaculation (PE) are common sexual dysfunctional diseases in adult males. With the acceleration of modern society rhythm, the increase of study, life and working pressure, and because of environmental pollution, the factor such as bad life style increase leads to impotence, the incidence and the rate of seeing a doctor of premature ejaculation improve year by year, because impotence is also called "sexuality can" and has definitional definitions of discriminativity, have brought huge physiology and psychological pressure to the patient.

At present, most of the medicinal preparations for treating the diseases at home and abroad are drugs for promoting and tonifying yang or vasodilators influencing NO metabolism, and when the medicinal preparations are used temporarily, the medicinal preparations can help people to exhaust primordial qi and damage the health of human bodies. There are also many Chinese patent drugs available, but these drugs still have the following problems: firstly, most of the medicines are taken at the moment and have no effect when the medicines are stopped; in addition, the existing medicines can take effect only after being taken due to external stimulation and enhancement of subjective desire. These drugs have short-term effects, and can only solve a problem of short time, and cannot achieve the purpose of regulating the endocrine and nervous systems of the human body. Therefore, it is necessary to develop a new medicine which has reliable curative effect, less adverse reaction and convenient use and treats both principal and secondary aspect of disease.

Disclosure of Invention

The invention designs and develops a traditional Chinese medicine composition for treating impotence and premature ejaculation, which adopts epimedium, morinda officinalis, pepper, gardenia, Chinese teasel root, achyranthes root, notopterygium root and wormwood as raw materials and can effectively treat the impotence and premature ejaculation.

The invention designs and develops a preparation method of a traditional Chinese medicine composition for treating impotence and premature ejaculation, and the extract is obtained in the preparation process, so that the effective components of the medicine are fully released and exerted, and the absorption of each component is promoted.

The invention designs and develops application of a traditional Chinese medicine composition for treating impotence and premature ejaculation, and the application of the traditional Chinese medicine composition for preparing foot bath liquid for treating impotence and premature ejaculation.

The technical scheme provided by the invention is as follows:

a Chinese medicinal composition for treating impotence and premature ejaculation comprises:

the traditional Chinese medicine composition comprises the following components in parts by weight:

95-105 parts of epimedium, 95-105 parts of morinda officinalis, 95-105 parts of pepper, 95-105 parts of gardenia, 95-105 parts of teasel root, 195-205 parts of achyranthes bidentata, 95-105 parts of notopterygium root and 115-125 parts of wormwood.

Preferably, the traditional Chinese medicine composition comprises the following components in parts by weight:

100 parts of epimedium, 100 parts of morinda officinalis, 100 parts of pepper, 100 parts of gardenia, 100 parts of teasel root, 200 parts of achyranthes root, 100 parts of notopterygium root and 120 parts of wormwood.

A preparation method of a traditional Chinese medicine composition for treating impotence and premature ejaculation is used for preparing the traditional Chinese medicine composition and comprises the following steps:

step one, weighing component medicinal materials such as epimedium, morinda officinalis, pepper, gardenia, teasel root, achyranthes, notopterygium root and wormwood according to parts by weight, and processing the component medicinal materials into powder;

step two, adding water to the powdery material for multiple times for extraction, filtering, and combining to obtain an extracting solution;

step three, concentrating the extracting solution into extract;

and step four, adding auxiliary materials into the extract to prepare a gel or an oral preparation.

Preferably, in the step one, the method for processing the component medicinal materials into the powdery material comprises the following steps:

and putting the component medicinal materials into a grinder to be ground into powder, and sieving the powder through a 100-mesh sieve to obtain the powdery material.

Preferably, in the second step, water is added for extraction twice;

wherein, 10 times of water is added into the powdery material for the first time to be decocted for 2 hours; adding 6 times of water into the residue for decocting for 1 hr.

Preferably, in the third step, the density ratio of the extract to the extracting solution is 1.2: 1.

Preferably, the oral dosage form is: tablet, capsule, microcapsule, granule, pill, powder, oral liquid, dripping pill, sustained release preparation or controlled release preparation.

Preferably, the auxiliary materials added for preparing the oral dosage form are as follows: one or more of diluent, disintegrant, excipient, binder, lubricant, surfactant, filler, preservative, stabilizer, flavoring agent, thickener and cosolvent.

Preferably, the auxiliary materials added for preparing the gel comprise: carbomer, diethanolamine, and sodium benzoate.

The application of the traditional Chinese medicine composition for treating impotence and premature ejaculation is characterized in that the traditional Chinese medicine composition in the form of gel is added into water to be dissolved to obtain foot bath liquid.

The invention has the beneficial effects that:

the traditional Chinese medicine composition selects eight traditional Chinese medicinal materials of epimedium, morinda officinalis, pepper, gardenia, Chinese teasel root, achyranthes root, notopterygium root and wormwood as raw materials, has the effects of nourishing yin and tonifying yang, strengthening kidney and calming heart, tonifying primordial qi, nourishing blood and producing sperm, is mainly used for treating impotence, premature ejaculation and sexual function decline, has the effects of building up body and resisting fatigue, has mild medicinal properties and obvious curative effect, and treats both principal and secondary aspect of disease.

The prepared extract in the preparation process can effectively and fully release and exert the pharmaceutical ingredients, promotes the absorption of the ingredients, has no toxic or side effect, and is safe and reliable.

The preparation method is simple, mature in process, natural in raw materials, convenient to use, environment-friendly and suitable for large-scale production.

Detailed Description

The present invention is described in further detail below to enable those skilled in the art to practice the invention with reference to the description.

The invention provides a traditional Chinese medicine composition for treating impotence and premature ejaculation, which comprises the following components in parts by mass:

95-105 parts of epimedium, 95-105 parts of morinda officinalis, 95-105 parts of pepper, 95-105 parts of gardenia, 95-105 parts of teasel root, 195-205 parts of achyranthes bidentata, 95-105 parts of notopterygium root and 115-125 parts of wormwood.

As a further optimization, the traditional Chinese medicine composition comprises the following components in parts by mass:

100 parts of epimedium, 100 parts of morinda officinalis, 100 parts of pepper, 100 parts of gardenia, 100 parts of teasel root, 200 parts of achyranthes root, 100 parts of notopterygium root and 120 parts of wormwood.

The weight parts of the invention are units of gram, two, kilogram and the like.

The invention also provides a preparation method of the traditional Chinese medicine composition for treating impotence and premature ejaculation, which is used for preparing the traditional Chinese medicine composition and comprises the following steps:

step one, weighing component medicinal materials such as epimedium, morinda officinalis, pepper, gardenia, teasel root, achyranthes, notopterygium root and wormwood according to parts by weight, and processing the component medicinal materials into powder;

step two, adding water to the powdery material for multiple times for extraction, filtering, and combining to obtain an extracting solution;

step three, concentrating the extracting solution into extract;

and step four, adding auxiliary materials into the extract to prepare a gel or an oral preparation.

Wherein the oral dosage form is: tablet, capsule, microcapsule, granule, pill, powder, oral liquid, dripping pill, sustained release preparation or controlled release preparation.

The auxiliary materials added for preparing the oral preparation are as follows: one or more of diluent, disintegrant, excipient, binder, lubricant, surfactant, filler, preservative, stabilizer, flavoring agent, thickener and cosolvent.

The auxiliary materials added for preparing the gel comprise: carbomer, diethanolamine, and sodium benzoate.

In another embodiment, in the step one, the method for processing the component medicinal materials into the powdery material comprises the following steps: and putting the medicinal materials of epimedium, morinda officinalis, pepper, gardenia, Chinese teasel root, achyranthes root, notopterygium root and wormwood into a crusher, crushing into powder, and sieving by a 100-mesh sieve to obtain the powdery material.

In another embodiment, in the second step, water extraction is performed twice, and the two extracts are obtained after filtration and combination. The specific process comprises the following steps:

extracting for the first time: adding 10 times of water into the powdery material, decocting for 2h at 100 ℃, and filtering to obtain a first extracting solution; and (3) second extraction: adding 6 times of water into the residue after the first extraction and filtration, decocting for 1h at 100 ℃, and filtering to obtain a second extraction solution; thereafter, the first extract is combined with

And combining the second extracting solution to obtain the final extracting solution.

In another embodiment, in the third step, the extracting solution is concentrated into an extract, wherein the density ratio of the extract to the extracting solution is 1.2: 1.

The application of the traditional Chinese medicine composition for treating impotence and premature ejaculation is characterized in that the traditional Chinese medicine composition in the form of gel is added into water to be dissolved to obtain foot bath liquid.