阅读说明：本技术 在线试剂调整方法、装置及分析检测系统 (Online reagent method of adjustment, device and analysis detection system ) 是由 陈建林 于 2019-08-13 设计创作，主要内容包括：本发明提供了一种在线试剂调整方法、装置及分析检测系统,涉及生物科技领域。该在线试剂调整方法,包括：检测到在线试剂调整申请指令,向试剂存放装置发送第一控制指令,向上位机发送第一反馈指令,第一控制指令用于控制试剂存放装置进入试剂调整准备状态,第一反馈指令用于控制上位机显示申请处理提示信息；获取已有的所有任务队列；确定已有的所有任务队列中的目标任务被完成,向试剂存放装置发送第二控制指令,向上位机发送第二反馈指令,第二控制指令用于控制试剂存放装置进入试剂调整状态,第二反馈指令用于控制上位机显示申请成功提示信息,目标任务为最后使用试剂存放装置的任务。利用本发明的技术方案能够提高分析检测系统的检测效率。(The present invention provides a kind of online reagent method of adjustment, device and analysis detection systems, are related to technical field of biology.The online reagent method of adjustment, it include: to detect online reagent adjustment application instruction, the first control instruction is sent to reagent storage device, the first feedback command is sent to host computer, first control instruction enters reagent adjustment preparation state for controlling reagent storage device, and the first feedback command is for controlling host computer display application processing prompt information；Obtain existing all task queues；Determine that the goal task in existing all task queues is completed, the second control instruction is sent to reagent storage device, the second feedback command is sent to host computer, second control instruction enters reagent adjustment state for controlling reagent storage device, second feedback command applies for successfully prompt information for controlling host computer display, and goal task is last the using reagent storage device of the task.It can be improved the detection efficiency of analysis detection system using technical solution of the present invention.)

1. a kind of online reagent method of adjustment characterized by comprising

It detects the adjustment application instruction of online reagent, sends the first control instruction to reagent storage device, send the to host computer One feedback command, first control instruction enters reagent adjustment preparation state for controlling the reagent storage device, described First feedback command is used for table for controlling the host computer display application processing prompt information, the application processing prompt information It levies the reagent storage device and enters reagent adjustment preparation state；

Obtain existing all task queues；

It determines that the goal task in existing all task queues is completed, sends the second control to reagent storage device and refer to It enables, sends the second feedback command to host computer, second control instruction enters reagent for controlling the reagent storage device Adjustment state, second feedback command applies for successfully prompt information for controlling the host computer display, described to apply successfully Prompt information enters reagent adjustment state for characterizing the reagent storage device, and the goal task is finally to use the examination The task of agent storing unit.

2. the method according to claim 1, wherein the mesh in the determination existing all task queues Mark task is completed, comprising:

Obtain the task in existing all task queues；

According to inactive before goal task described in the inactive goal task and existing all task queues Task, determine control temporal information；

If current time reaches control temporal information instruction, the mesh in existing all task queues is determined Mark task is completed.

3. according to the method described in claim 2, it is characterized in that, described according to the target inactive in the task Inactive task before task and the goal task determines after controlling temporal information, further includes:

Duration between at the time of current time to the control temporal information is indicated is as waiting time；

To the host computer send third feedback command, the third feedback command for control the host computer show it is described etc. To duration.

4. the method according to claim 1, wherein detect the adjustment application instruction of online reagent described, to Host computer is sent before the first feedback command, further includes:

If it is determined that the amount of reagent of at least one reagent is lower than reagent threshold value in the reagent storage device, the online reagent is generated Adjustment application instruction；

Alternatively,

If receiving the reagent adjustment request instruction of user's input, the online reagent adjustment application instruction is generated.

5. the method according to claim 1, wherein referring to described to the second control of reagent storage device transmission It enables, after sending the second feedback command to host computer, further includes:

If detecting, the reagent storage device will enter maintenance state or reset state, and Xiang Suoshu reagent storage device is sent Third control instruction, Xiang Suoshu host computer send the 4th feedback command；

Alternatively,

If the processing to task will be started by detecting the reagent storage device, Xiang Suoshu reagent storage device sends described the Three control instructions, Xiang Suoshu host computer send the 4th feedback command；

Alternatively,

If detecting, the reagent storage device is abnormal, and Xiang Suoshu reagent storage device sends the third control instruction, The 4th feedback command is sent to the host computer；

Wherein, the third control instruction exits reagent adjustment state for controlling the reagent storage device, and described the Four feedback commands are for prompting the reagent storage device to exit the reagent adjustment state.

6. the method according to claim 1, wherein further include:

If detecting, at least part reagent in the reagent storage device has been adjusted, and is rescaned the acquisition reagent and is deposited Put the reagent information of reagent in device；

According to the reagent information of reagent in the reagent storage device of the reacquisition, the reagent storage device pair is updated The reagent information database answered.

7. the method according to claim 1, wherein further include:

If detecting, the reagent storage device exits the reagent adjustment state, and Xiang Suoshu reagent storage device sends the 4th control System instruction, the 4th control instruction are used to control the reagent storage device and carry out to the reagent in the reagent storage device Mix operation.

8. the method according to claim 1, wherein further include:

It determines that the goal task in existing all task queues is completed, sends the 5th control to sample processing apparatus and refer to It enables, the sample of inactive sample-adding task is retracted into placement for controlling the sample processing apparatus by the 5th control instruction Area.

9. a kind of online reagent adjusts device characterized by comprising

Signal transmitting and receiving module sends the first feedback command to host computer for sending the first control instruction to reagent storage device, First control instruction enters reagent adjustment preparation state, first feedback command for controlling the reagent storage device For controlling the host computer display application processing prompt information, the application processing prompt information is deposited for characterizing the reagent It puts device and enters reagent adjustment preparation state；

Task sorting module, for obtaining existing all task queues；

The signal transmitting and receiving module is also used to determine that the goal task in existing all task queues is completed, to examination Agent storing unit sends the second control instruction, sends the second feedback command to host computer, second control instruction is for controlling The reagent storage device enters reagent adjustment state, second feedback command for control host computer display application at Function prompt information, it is described apply successfully prompt information for characterize the reagent storage device enter reagent adjustment state, it is described Goal task is finally the using the reagent storage device of the task.

10. a kind of analysis detection system characterized by comprising

Online reagent as claimed in claim 9 adjusts device；

Reagent storage device, the first control instruction sent for receiving the online reagent adjustment device, and according to described the One control instruction enters reagent adjustment preparation state, and, the second control sent for receiving the online reagent adjustment device System instruction, and reagent adjustment state is entered according to second control instruction；

Host computer, the first feedback command sent for receiving the online reagent adjustment device, and according to first feedback Instruction display application processing prompt information, and, the second feedback command sent for receiving the online reagent adjustment device, And successfully prompt information is applied for according to second feedback command display；

Wherein, the application processing prompt information enters reagent adjustment preparation state, institute for characterizing the reagent storage device State apply successfully prompt information for characterize the reagent storage device enter reagent adjustment state.

Technical field

The invention belongs to technical field of biology more particularly to a kind of online reagent methods of adjustment, device and analysis detection system System.

Background technique

During carrying out biologic medical detection, reagent need to be taken using special analysis detection system, by reagent plus Enter into sample to be tested, and is detected.

Storage detects the kit of consumptive material equipped with reagent etc. in the reagent storage device of analysis detection system, using probe or Other devices carry out the movement of reagent taken and reagent (being referred to as loaded) is added into sample.In the detection process, reagent It can be gradually used up Deng detection consumptive material.It in the case that detection consumptive material exhausts, can only stop being loaded, analysis detection system is waited to complete Detection to the sample to be tested being loaded, and reagent storage device is under shutdown status, can just be carried out to reagent storage device The movements such as addition detection consumptive material, replacement detection consumptive material and unloading detection consumptive material, reduce the efficiency of detection.

Summary of the invention

The embodiment of the invention provides a kind of online reagent method of adjustment, device and analysis detection system, can be improved point Analyse the detection efficiency of detection system.

In a first aspect, the embodiment of the invention provides a kind of online reagent methods of adjustment, comprising: detect online reagent tune Whole application instruction, sends the first control instruction to reagent storage device, sends the first feedback command to host computer, the first control refers to It enables and enters reagent adjustment preparation state for controlling reagent storage device, the first feedback command is for controlling host computer display application Prompt information is handled, application processing prompt information enters reagent adjustment preparation state for characterizing reagent storage device；It obtains All task queues having；It determines that the goal task in existing all task queues is completed, is sent to reagent storage device Second control instruction sends the second feedback command to host computer, and the second control instruction enters examination for controlling reagent storage device Agent adjusts state, and the second feedback command applies for successfully prompt information for controlling host computer display, applies for successfully prompt information use Enter reagent adjustment state in characterization reagent storage device, goal task is last the using reagent storage device of the task.

Second aspect, the embodiment of the invention provides a kind of online reagents to adjust device, comprising: signal transmitting and receiving module is used In sending the first control instruction to reagent storage device, the first feedback command is sent to host computer, the first control instruction is for controlling Reagent storage device processed enters reagent adjustment preparation state, and the first feedback command is for controlling host computer display application processing prompt Information, application processing prompt information enter reagent adjustment preparation state for characterizing reagent storage device；Task sorting module is used In the existing all task queues of acquisition；Signal transmitting and receiving module is also used to determine that the target in existing all task queues is appointed Business is completed, and sends the second control instruction to reagent storage device, sends the second feedback command, the second control instruction to host computer Enter reagent adjustment state for controlling reagent storage device, the second feedback command is applied successfully mentioning for controlling host computer display Show information, applies for that successfully prompt information is used to characterize reagent storage device and enter reagent adjustment state, goal task is finally to make With the task of reagent storage device.

The third aspect, the embodiment of the invention provides a kind of analysis detection systems, comprising: in the technical solution of second aspect Online reagent adjust device；Reagent storage device, the first control instruction sent for receiving online reagent adjustment device, and Enter reagent adjustment preparation state according to the first control instruction, and, second sent for receiving online reagent adjustment device Control instruction, and reagent adjustment state is entered according to the second control instruction；Host computer, for receiving online reagent adjustment device hair The first feedback command sent, and application processing prompt information is shown according to the first feedback command, and, for receiving online reagent The second feedback command that device is sent is adjusted, and successfully prompt information is applied for according to the display of the second feedback command；Wherein, at application Reason prompt information enters reagent adjustment preparation state for characterizing reagent storage device, applies for that successfully prompt information is for characterizing examination Agent storing unit enters reagent adjustment state.

The embodiment of the present invention provides a kind of online reagent method of adjustment, device and analysis detection system, can detect In the case where the adjustment application instruction of line reagent, control reagent storage device enters reagent adjustment preparation state, and controls host computer Display application processing prompt information.In the process, existing all task queues are obtained, determine existing all task teams Goal task in column is completed, control reagent storage device enter reagent adjustment state, and control host computer display application at Function prompt information.So that in the case where task relevant to reagent storage device terminates, to the reagent that still do not shut down online Storing unit carries out in the operations such as reagent increases, reagent is replaced or reagent unloads and analysis detection system except reagent storage device Device in addition can synchronize progress to the processing of task also unfinished in existing all task queues.It withouts waiting for Whole tasks are processed in all task queues having finishes and reagent storage device is under shutdown status again to reagent Storing unit carries out the operations such as reagent increases, reagent is replaced or reagent unloads.Reagent storage device is tried to reduce The time waited required for the operations such as agent increases, reagent is replaced or reagent unloads, improve the detection efficiency of analysis detection system.

Detailed description of the invention

The present invention may be better understood from the description with reference to the accompanying drawing to a specific embodiment of the invention wherein, The same or similar appended drawing reference indicates the same or similar feature.

Fig. 1 is a kind of schematic diagram of the part-structure of analysis detection system in the embodiment of the present invention；

Fig. 2 is a kind of flow chart of online reagent method of adjustment in one embodiment of the invention；

Fig. 3 is a kind of flow chart of online reagent method of adjustment in another embodiment of the present invention；

Fig. 4 is a kind of structural schematic diagram of online reagent adjustment device in one embodiment of the invention.

Specific embodiment

The feature and exemplary embodiment of various aspects of the invention is described more fully below.In following detailed description In, many details are proposed, in order to provide complete understanding of the present invention.But to those skilled in the art It will be apparent that the present invention can be implemented in the case where not needing some details in these details.Below to implementation The description of example is used for the purpose of providing by showing example of the invention and better understanding of the invention.The present invention never limits In any concrete configuration set forth below and algorithm, but cover under the premise of without departing from the spirit of the present invention element, Any modification, replacement and the improvement of component and algorithm.In the the accompanying drawings and the following description, well known structure and skill is not shown Art is unnecessary fuzzy to avoid causing the present invention.

The embodiment of the invention provides a kind of online reagent method of adjustment, device and analysis detection systems, can be used for needing Reagent storage device is carried out in the scene that reagent increases, reagent is replaced or reagent unloads.Fig. 1 is a kind of in the embodiment of the present invention The schematic diagram of the part-structure of analysis detection system.As shown in Figure 1, in some instances, reagent storage device can be agent bin 11, agent bin 11 is for storing reagent.Specifically, agent bin 11 can be the circle tub configurations with top cover.It is settable on top cover There is door, door is openable or closes.In some instances, door can be opened or closed around the rotary shaft for being set to top cover.Examination The containers such as multiple kits can be placed in agent storehouse 11, the containers such as kit are for holding reagent.Agent bin 11 can be around agent bin 11 Central point clockwise or counterclockwise, agent bin 11 rotation can drive the containers such as kit rotate.Analysis detection system is also It may include specimen needle 12, specimen needle 12 is used to take reagent, and reagent is added to sample.

It, specifically can be with it should be noted that " reagent " in the embodiment of the present invention is consumptive material used in detection process For liquid reagent, solid reagent, dilution etc., do not limit herein.

As reagent is drawn, the amount of reagent of reagent is gradually decreased, until being exhausted.At this stage, if amount of reagent consumes It finishes, and a series of existing tasks of analysis detection system are not fully completed also, then need to wait each in analysis detection system A series of tasks are fully completed and when reagent storage device are in shutdown status by a device, just can to reagent storage device into The operations such as row reagent increases, reagent is replaced or reagent unloads.For example, if existing all task queue packets in analysis detection system Include the sample-adding task of ten samples and the Detection task of this ten samples.When reagent is exhausted, five samples are had been completed This sample-adding task, but do not complete the Detection task of this five samples, and, do not complete other five samples sample-adding task and Detection task.After the completion of then needing to wait and having completed the corresponding Detection task of five samples of sample-adding task also, and reagent is deposited Device shutdown is put, the operations such as reagent increases, reagent is replaced or reagent is unloaded can be carried out to reagent storage device.Reagent storage Operation the waited times such as device progress reagent increases, reagent is replaced or reagent unloads are longer, affect analysis detection system Detection efficiency.

A kind of reagent method of adjustment is now needed, is reduced to reagent storage device progress reagent increases, reagent is replaced or reagent The time waited required for the operation such as unloading, improve the detection efficiency of analysis detection system.Fig. 2 is one in one embodiment of the invention The flow chart of the online reagent method of adjustment of kind.Online reagent method of adjustment can have control function by controller, control module etc. Module, unit, device, equipment etc. execute, do not limit herein.For ease of description, online examination is executed with controller below It is illustrated for agent method of adjustment.As shown in Fig. 2, online reagent method of adjustment may include step S201 to step S203.

In step s 201, it detects online reagent adjustment application instruction, sends the first control to reagent storage device and refer to It enables, sends the first feedback command to host computer.

Wherein, online reagent adjustment application instruction carries out online reagent adjustment for characterizing request.Reagent adjusts The operations such as reagent increases, reagent is replaced or reagent unloads, do not limit herein.

First control instruction enters reagent adjustment preparation state for controlling reagent storage device.That is reagent storage device connects First control instruction is received, then enters reagent and adjusts preparation state.It is into before reagent adjustment state that reagent, which adjusts preparation state, Preparation state.In reagent adjustment preparation state, the performance of the task in task queue and task queue can be carried out It determines.

First feedback command is for controlling host computer display application processing prompt information.Application processing prompt information is used for table Sign reagent storage device enters reagent adjustment preparation state.Host computer concretely special equipment, computer, tablet computer, mobile phone Etc. equipment, do not limit herein.The preparation that application processing prompt information can be used for that prompt operator is assisted to carry out reagent adjustment Work.The particular content of application processing prompt information does not limit herein.For example, can be shown on the working interface of host computer The printed words or picture of " application ".For another example, the indicator light that the expression of host computer is being applied can be lighted.

In step S202, existing all task queues are obtained.

Controller obtains existing all task queues in analysis detection system.In some instances, each sample can be right Answer a task queue.One task queue includes at least one task.Task may include taking liquid task, sample-adding task, detection Task, cleaning task etc..Wherein, task number and specific tasks can be different in different task queue, can also be identical.One It may include that multiple congener tasks can also wrap for example, a task queue may include a sample-adding task in a task queue Multiple sample-adding tasks are included, are not limited herein.

In step S203, determine that the goal task in existing all task queues is completed, to reagent storage device The second control instruction is sent, sends the second feedback command to host computer.

Wherein, goal task is last the using reagent storage device of the task.In all task queues, deposited using reagent Put device task might have it is multiple.If goal task is completed in existing all task queues, subsequent task is not Reagent storage device can be reused.Reagent storage device can enter reagent and adjust state.It, can be to examination in reagent adjustment state Agent storing unit carries out the operations such as reagent increases, reagent is replaced or reagent unloads.It should be noted that specific reagent increases, tries Agent replacement or reagent unloading etc. operations operation realization manually can be carried out to reagent storage device by operator, can also by for The operating device of reagent storage device configuration, which operates, to be realized, is not limited herein.

Second control instruction enters reagent adjustment state for controlling the reagent storage device.Pass through the second control System instruction control reagent storage device enters reagent adjustment state.Reagent storage device receives the second control instruction, then enters examination Agent adjusts state.

Second feedback command applies for successfully prompt information for controlling host computer display.Apply for that successfully prompt information is used for table Sign reagent storage device enters reagent adjustment state.Apply for that successfully prompt information can be used for assisting prompt operator that can try The operation of agent adjustment.Apply for that the particular content of successfully prompt information does not limit herein.For example, can be in the working interface of host computer The printed words or picture of upper display " applying successfully ".For another example, the successful indicator light of expression application of host computer can be lighted.

It should be noted that in the case where reagent storage device enters reagent adjustment state, in analysis detection system Other devices can also be handled task.For example, detection device can continue with Detection task.That is, being deposited to reagent The operations such as the carry out reagent for putting device increases, reagent replacement or reagent unloading, can be with other devices in analysis detection system Task processes are synchronous to be carried out.

In embodiments of the present invention, reagent storage can be controlled in the case where detecting online reagent adjustment application instruction Device enters reagent adjustment preparation state, and controls host computer display application processing prompt information.In the process, it obtains existing All task queues, determine that the goal task in existing all task queues is completed, control reagent storage device into Enter reagent adjustment state, and controls host computer display and apply for successfully prompt information.So that at relevant to reagent storage device In the case that business terminates, the reagent storage device progress reagent that still do not shut down online is increased, reagent replacement or reagent unload Deng device in addition to reagent storage device in operation and analysis detection system to also not complete in existing all task queues At the processing of task can synchronize progress.Without waiting in existing all task queues that whole task is processed finishes And reagent storage device is under shutdown status and carries out reagent increases, reagent is replaced or reagent unloads etc. to reagent storage device again Operation.Reagent storage device wait required for the operations such as reagent increases, reagent is replaced or reagent unloads to reduce Time, improve analysis detection system detection efficiency.

Under identical condition, the time waited using prior art progress reagent adjustment will be considerably longer than using this hair Online reagent method of adjustment in bright embodiment carries out the time that reagent adjustment is waited.For example, under identical condition, using The prior art needs to wait 30 minutes before carrying out specific reagent adjustment or the longer time；And it uses in the embodiment of the present invention Online reagent method of adjustment only needs to wait 14 minutes or less time before carrying out specific reagent adjustment.

Fig. 3 is a kind of flow chart of online reagent method of adjustment in another embodiment of the present invention.Fig. 3 it is different from Fig. 2's it It is in the step S203 in Fig. 2 can specifically be refined as the step S2031 to step S2034 in Fig. 3.In some instances, may be used Triggering generates online reagent adjustment application instruction, corresponding, online reagent adjustment side shown in Fig. 3 under conditions of some settings Method may also include step S204 or step S205.In some instances, the update of reagent information can be also carried out after reagent adjustment, Corresponding, online reagent method of adjustment shown in Fig. 3 may also include step S206 and step S207.

In step S204, however, it is determined that the amount of reagent of at least one reagent is lower than reagent threshold value in reagent storage device, raw Application instruction is adjusted at online reagent.

In this example, reagent threshold value is the relatively low alert thresholds of amount of reagent.If the reagent of reagent in reagent storage device Amount be lower than reagent threshold value, indicate that the reagent will be consumed and finish, need to reagent storage device carry out reagent increase, reagent more It changes or the operations such as reagent unloading, for example increases in reagent storage device the type reagent or by amount of reagent lower than reagent threshold value Reagent unloaded from reagent storage device, and new reagent is replaced to the position for the reagent being unloaded.

In step S205, if receiving the reagent adjustment request instruction of user's input, generates online reagent adjustment application and refer to It enables.

In this example, controller can receive the reagent adjustment request instruction of user's input, the online reagent tune of in-time generatin Whole application instruction.For example, showing reagent adjustment application button on human-computer interaction interface, user clicks reagent adjustment application Button, controller receive the reagent adjustment request instruction of user's input, carry out relevant operation.

In step S2031, the task in existing all task queues is obtained.

In the case where detecting online reagent adjustment application instruction, goal task is possible to not be completed also.Controller It needs according to the case where each task, determining triggering control reagent storage device enters reagent tune in existing all task queues The opportunity of whole state.

In step S2032, before goal task in inactive goal task and existing all task queues Inactive, determine control temporal information.

If the task in task queue is being analyzed the processing of the device in detection system or is being disposed, this Business is having been turned on for task.If the device processing in the also not analyzed detection system of task in task queue, the task are Inactive task.

Specifically, can obtain handling the time that inactive goal task needs to spend according to inactive goal task. It is inactive before processing target task can be obtained according to task inactive before existing all task queue goal tasks Task the time it takes.Before the time for needing to spend based on the inactive goal task of processing and processing target task Inactive task the time it takes, it may be determined that control temporal information.It can be obtained according to control temporal information to reagent storage At the time of device sends the first control instruction.In some instances, control temporal information can characterize sometime, then control the time At the time of at the time of information indicates being control temporal information characterization.In another example, control temporal information can characterize duration, Then control temporal information instruction at the time of for current time through control temporal information characterization duration after at the time of.

Wherein, if control temporal information characterizes duration, the duration characterized, which is longer than to be equal to, handles inactive goal task Inactive the sum of task the time it takes before the time for needing to spend and processing target task.If controlling temporal information table Levy the moment, then at the time of characterization for current time after target duration at the time of, target duration be longer than be equal to handle it is inactive Goal task need the sum of task the time it takes inactive before time for spending and processing target task.

In some instances, the duration between at the time of can indicating current time to control temporal information is as when waiting It is long.Controller can send third feedback command to host computer.When third feedback command shows the waiting for controlling host computer It is long.To make operator that can be intuitively known when reagent storage device can enter reagent adjustment state.Specifically, can be upper The working interface of position machine shows the waiting time, and carries out countdown.

In step S2033, if current time reaches control temporal information instruction, existing all tasks are determined Goal task in queue is completed.

At the time of current time reaches control temporal information instruction, indicate whole using the task of reagent storage device It is completed, the operations such as reagent increases, reagent is replaced or reagent is unloaded can be carried out to reagent storage device, it therefore, can be to reagent Storing unit sends the second control instruction, sends the second feedback command to host computer.

In step S2034, the second control instruction is sent to reagent storage device, the second feedback is sent to host computer and refers to It enables.

In step S206, if detecting, at least part reagent in reagent storage device has been adjusted, and is rescaned Obtain the reagent information of reagent in reagent storage device.

It should be noted that reagent here be adjusted increase including reagent, reagent replacement or reagent unloading etc..Reagent is deposited The reagent put in device is adjusted, then the reagent information of reagent changes in reagent storage device.For the ease of being deposited to reagent The monitoring of the reagent in device is put, the reagent information for obtaining reagent in reagent storage device can be rescaned.For example, reagent storage Device can scan the kit in reagent storage device on each position, and record has the reagent of reagent in kit to believe on kit Breath.

In step S207, according to the reagent information of reagent in the reagent storage device of reacquisition, reagent storage is updated The corresponding reagent information database of device.

The reagent information of reagent in the reagent storage device of scanning acquisition can be uploaded to reagent information database, to update Reagent information in reagent information database.In some instances, the reagent on reagent information database and human-computer interaction interface Synchronizing information updates, so that operator can intuitively obtain newest reagent information.

Reagent storage device can also exit reagent adjustment state.It in embodiments of the present invention, can be by being filled to reagent storage It sets and sends third control instruction, control reagent storage device exits reagent adjustment state.It can also be by sending the 4th to host computer Feedback command prompts reagent storage device to exit reagent adjustment state.

After reagent storage device exits reagent adjustment state, reagent storage device progress reagent can not be increased again, The operation such as reagent replacement or reagent unloading.Enter reagent adjustment state in reagent storage device and reagent storage device exits reagent Between adjustment state, the operations such as a reagent increases, reagent is replaced or reagent is unloaded can be carried out to reagent storage device, can also be weighed The operations such as multiple reagent increases, reagent is replaced or reagent unloads are carried out again, are not limited herein.

In some instances, if detecting, reagent storage device will enter maintenance state or reset state, deposit to reagent It puts device and sends third control instruction, send the 4th feedback command to host computer.

After reagent storage device enters maintenance state or reset state, reagent increasing can not be carried out to reagent storage device again Add, reagent replacement or reagent unloading etc. operation.Therefore, it is necessary to enter it of maintenance state or reset state in reagent storage device Before exit reagent adjustment state.For example, controller receives maintenance instruction or reset instruction, the first is sent to reagent storage device Three control instructions send the 4th feedback command to host computer, then carry out attended operation or reset to grasp to reagent storage device again Make.

In other examples, if detecting, reagent storage device will start the processing of task, to reagent storage device Third control instruction is sent, sends the 4th feedback command to host computer.

After carrying out the operations such as reagent increases, reagent is replaced or reagent is unloaded to reagent storage device, reagent storage dress Set the processing that can start to task.It and in the process of processing, is being that reagent storage device can not be tried to task The operations such as agent increases, reagent is replaced or reagent unloads.Therefore, it is necessary to the starting of reagent storage device to the processing of task it Before, control reagent storage device exits reagent adjustment state.

In other example, if detecting, reagent storage device is abnormal, and sends third control to reagent storage device System instruction sends the 4th feedback command to host computer.

Reagent storage device may be abnormal, for example be broken down.In the feelings that reagent storage device is abnormal Under condition, the operations such as reagent increases, reagent is replaced or reagent is unloaded can not be carried out to reagent storage device.Therefore, if inspection It measures reagent storage device to be abnormal, control reagent storage device exits reagent adjustment state.

If detecting, reagent storage device exits reagent adjustment state, can start the processing to new task.In order to which reagent is deposited Sample-adding task can directly be participated in by putting the reagent in device, not influence testing result, if detecting, reagent storage device exits reagent Adjustment state sends the 4th control instruction to reagent storage device.4th control instruction is for controlling reagent storage device to examination Reagent in agent storing unit carries out mixing operation.Reagent by mixing operation can directly participate in sample-adding task, for example, containing The reagent of magnetic bead controls reagent storage device by the 4th control instruction and carries out mixing behaviour to the reagent in reagent storage device Make, so that the magnetic bead even suspension in reagent, the reagent for taking magnetic bead even suspension participates in sample-adding task and Detection task, even if It is the reagent of the reagent or replacement increased, testing result will not be influenced.

In some instances, however, it is determined that the goal task in existing all task queues is completed, can also be at sample It manages device and sends the 5th control instruction.Sample processing apparatus can handle sample-adding task, Detection task etc..5th control instruction is used for It controls sample processing apparatus and the sample of inactive sample-adding task is retracted into rest area.The sample for being retracted into rest area, which is not involved in, appoints Business.

Specifically, rest area includes but is not limited to and the structures such as the sample channel of sample processing apparatus configuration setting.

Fig. 4 is a kind of structural schematic diagram of online reagent adjustment device in one embodiment of the invention.As shown in figure 4, being somebody's turn to do It includes signal transmitting and receiving module 301 and task sorting module 302 that line reagent, which adjusts device 300,.

It is anti-to send first to host computer for sending the first control instruction to reagent storage device for signal transmitting and receiving module 301 Feedback instruction.

Wherein, the first control instruction enters reagent adjustment preparation state for controlling reagent storage device.First feedback refers to It enables for controlling host computer display application processing prompt information.Application processing prompt information is for characterizing the entrance of reagent storage device Reagent adjusts preparation state.

Task sorting module 302, for obtaining existing all task queues.

Signal transmitting and receiving module 301 is also used to determine that the goal task in existing all task queues is completed, to reagent Storing unit sends the second control instruction, sends the second feedback command to host computer.

Wherein, the second control instruction enters reagent adjustment state for controlling reagent storage device.Second feedback command is used Apply for successfully prompt information in control host computer display.Apply for that successfully prompt information is used to characterize reagent storage device and enters reagent Adjustment state.Goal task is last the using reagent storage device of the task.

In embodiments of the present invention, reagent storage can be controlled in the case where detecting online reagent adjustment application instruction Device enters reagent adjustment preparation state, and controls host computer display application processing prompt information.In the process, it obtains existing All task queues, determine that the goal task in existing all task queues is completed, control reagent storage device into Enter reagent adjustment state, and controls host computer display and apply for successfully prompt information.So that at relevant to reagent storage device In the case that business terminates, the reagent storage device progress reagent that still do not shut down online is increased, reagent replacement or reagent unload Deng device in addition to reagent storage device in operation and analysis detection system to also not complete in existing all task queues At the processing of task can synchronize progress.Without waiting in existing all task queues that whole task is processed finishes And reagent storage device is under shutdown status and carries out reagent increases, reagent is replaced or reagent unloads etc. to reagent storage device again Operation.Reagent storage device wait required for the operations such as reagent increases, reagent is replaced or reagent unloads to reduce Time, improve analysis detection system detection efficiency.

In some instances, above-mentioned signal transmitting and receiving module 301 can be specifically used for obtaining in existing all task queues Task；According to task inactive before goal task in inactive goal task and existing all task queues, determine Control temporal information；If current time reaches control temporal information instruction, determine in existing all task queues Goal task is completed.

Further, above-mentioned signal transmitting and receiving module 301 can also be specifically used for current time to control temporal information instruction At the time of between duration as waiting time；Third feedback command is sent to host computer.

Wherein, third feedback command shows waiting time for controlling host computer.

In some instances, online reagent adjustment device 300 may also include generation module.

The generation module can be used for if it is determined that in reagent storage device the amount of reagent of at least one reagent lower than reagent threshold value, Generate online reagent adjustment application instruction.

If being instructed alternatively, the generation module can be used for the reagent adjustment request that the reception user of signal transmitting and receiving module 301 inputs, Generate online reagent adjustment application instruction.

In some instances, above-mentioned signal transmitting and receiving module 301 can also be used in: if detecting, reagent storage device will enter Maintenance state or reset state, send third control instruction to reagent storage device, send the 4th feedback command to host computer；Or Person, if detecting, reagent storage device will start the processing to task, send third control instruction to reagent storage device, to Host computer sends the 4th feedback command；Alternatively, if detecting, reagent storage device is abnormal, and sends the to reagent storage device Three control instructions send the 4th feedback command to host computer.

Wherein, third control instruction exits reagent adjustment state for controlling reagent storage device.4th feedback command is used Reagent adjustment state is exited in prompt reagent storage device.

In some instances, which may also include scan module and update module.

If scan module can be used for detecting that at least part reagent in reagent storage device has been adjusted, rescan Obtain the reagent information of reagent in reagent storage device.

Update module can be used for the reagent information of reagent in the reagent storage device according to reacquisition, update reagent storage The corresponding reagent information database of device.

In some instances, if above-mentioned signal transmitting and receiving module 301 can also be used to detect that reagent storage device exits reagent Adjustment state, Xiang Suoshu reagent storage device send the 4th control instruction.

Wherein, the 4th control instruction carries out mixing behaviour to the reagent in reagent storage device for controlling reagent storage device Make.

In some instances, above-mentioned signal transmitting and receiving module 301 can also be used to determine the mesh in existing all task queues Mark task is completed, and sends the 5th control instruction to sample processing apparatus.

Wherein, the sample of inactive sample-adding task is retracted into placement for controlling sample processing apparatus by the 5th control instruction Area.

The embodiment of the present invention also provides a kind of analysis detection system, which may include in above-described embodiment Online reagent adjustment device, reagent storage device and host computer.

Wherein, reagent storage device, the first control instruction sent for receiving the online reagent adjustment device, and root Enter reagent adjustment preparation state according to first control instruction, and, it is sent for receiving the online reagent adjustment device The second control instruction, and according to second control instruction enter reagent adjustment state.

Host computer, the first feedback command sent for receiving the online reagent adjustment device, and according to described first Feedback command display application processing prompt information, and, the second feedback sent for receiving the online reagent adjustment device Instruction, and successfully prompt information is applied for according to second feedback command display.

The related content of online reagent adjustment device can be found in the related description in above-described embodiment, and details are not described herein.

Application processing prompt information in above-described embodiment enters reagent adjustment preparation shape for characterizing reagent storage device State.Apply for that successfully prompt information is used to characterize reagent storage device and enters reagent adjustment state.

One embodiment of the application also provides a kind of storage medium, is stored with computer program on the storage medium, the calculating Machine program can realize the online reagent method of adjustment in above-described embodiment when being executed by processor.

It should be clear that all the embodiments in this specification are described in a progressive manner, each embodiment it Between the same or similar part may refer to each other, the highlights of each of the examples are it is different from other embodiments it Place.For Installation practice, analysis detection system embodiment and storage medium embodiment, related place may refer to method The declaratives of embodiment.The invention is not limited to particular step described above and shown in figure and structures.Ability The technical staff in domain can be variously modified, modification and addition, or change the step it after understanding spirit of the invention Between sequence.Also, the detailed description to known method technology for brevity, is omitted here.

Those skilled in the art will be understood that above-described embodiment is illustrative and not restrictive.In different embodiments The different technologies feature of middle appearance can be combined, to obtain beneficial effect.Those skilled in the art are in research attached drawing, explanation On the basis of book and claims, the embodiment of other variations of revealed embodiment is will be understood that and realized.In right In claim, term " comprising " is not precluded from other devices or steps；Indefinite article "one" be not excluded for it is multiple；Term " the One ", " second " is for indicating title not for any specific sequence of expression.Any appended drawing reference in claim is not It should be understood limiting of its scope.The function of the multiple portions occurred in claim can be by an individual hardware Or software module is realized.Certain technical characteristic appearance are not meant in different dependent claims cannot be by these skills Art feature is combined to obtain beneficial effect.