阅读说明：本技术 一种养殖场用消毒除臭纳米乳剂及制备方法和应用 (A kind of farm disinfecting, deodorizing nanoemulsion and preparation method and application ) 是由 王艳玲 庞云露 刘元元 孙亚磊 王英俊 崔栩 郑亚妮 盖新光 于 2019-09-29 设计创作，主要内容包括：本发明提供了一种养殖场用消毒除臭纳米乳剂,属于畜禽养殖领域。其技术方案为：纳米乳剂包括有效成分和辅料,有效成分包括聚六亚甲基胍或聚六亚甲基胍盐类,有效成分还包括缩氨酸、枯草溶菌素、大蒜油、龙脑、百里香酚、丁香酚、桉叶素、薄荷脑、香茅精油、藿香油,辅料包括表面活性剂、助表面活性剂,制药用水。本发明的有益效果为：本发明消毒除臭纳米乳剂的制备方法成本低廉、容易操作、并且所用试剂毒性较小,对生产人员的身体危害程度较低,有利于安全生产和环境保护,同时,消毒除臭纳米乳剂具有极强的杀灭细菌和病毒的能力,能够有效去除养殖场所异味,且广谱高效,具有长期抑菌作用；安全、无毒副作用。(The present invention provides a kind of farm disinfecting, deodorizing nanoemulsions, belong to livestock and poultry cultivation field.Its technical solution are as follows: nanoemulsion includes effective component and auxiliary material, effective component includes polyhexamethylene guanide or poly (hexamethylene) class, effective component further includes peptide, subtilisin, garlic oil, borneol, Thymol, eugenol, Cineole, menthol, oil of Cymbopogon winterianus, palchouli oil, auxiliary material includes surfactant, cosurfactant, water for pharmaceutical purposes.The invention has the benefit that the preparation method of disinfecting, deodorizing nanoemulsion of the present invention is low in cost, easy to operate and agents useful for same toxicity is smaller; it is lower to the body harm degree of producers; be conducive to safety in production and environmental protection; simultaneously; disinfecting, deodorizing nanoemulsion has the ability of extremely strong killing bacterium and virus; cultivation place peculiar smell, and broad-spectrum high efficacy can be effectively removed, there is long-term bacteriostasis；It is safe and free of toxic and side effects.)

1. a kind of farm disinfecting, deodorizing nanoemulsion, which is characterized in that the nanoemulsion includes effective component and auxiliary material, The effective component includes 1-30 parts of polyhexamethylene guanide or 1-30 parts of poly (hexamethylene) class, and the effective component further includes 1-25 parts of peptide, 1-25 parts of subtilisin, 1-15 parts of garlic oil, 1-15 parts of borneol, 1-15 parts of Thymol, eugenol 1- 10 parts, 1-10 parts of Cineole, 1-10 parts of menthol, 1-10 parts of oil of Cymbopogon winterianus, 1-10 parts of palchouli oil, the auxiliary material include that surface is living Property 5-20 parts of agent, 1-20 parts of cosurfactant, 5-20 parts of water for pharmaceutical purposes.

2. farm according to claim 1 disinfecting, deodorizing nanoemulsion, which is characterized in that the nanoemulsion includes Effective component and auxiliary material, the effective component include 15 parts of polyhexamethylene guanide, the effective component further include 17 parts of peptide, 16 parts of subtilisin, 8 parts of garlic oil, 7 parts of borneol, 7 parts of Thymol, 6 parts of eugenol, 7 parts of Cineole, 8 parts of menthol, perfume 6 parts of thatch essential oil, 6 parts of palchouli oil, the auxiliary material include 13 parts of surfactant, 14 parts of cosurfactant, and 14 parts of water for pharmaceutical purposes.

3. farm according to claim 1 disinfecting, deodorizing nanoemulsion, which is characterized in that the nanoemulsion includes Effective component and auxiliary material, the effective component include 10 parts of poly (hexamethylene) class, and the effective component further includes peptide 13 parts, 12 parts of subtilisin, 5 parts of garlic oil, 6 parts of borneol, 5 parts of Thymol, 4 parts of eugenol, 6 parts of Cineole, menthol 4 Part, 3 parts of oil of Cymbopogon winterianus, 5 parts of palchouli oil, the auxiliary material include 11 parts of surfactant, 8 parts of cosurfactant, water for pharmaceutical purposes 13 parts.

4. farm according to claim 1 disinfecting, deodorizing nanoemulsion, which is characterized in that the nanoemulsion be by Made of following method:

S1, appropriate polyhexamethylene guanide or poly (hexamethylene) class is taken to be dissolved in water for pharmaceutical purposes, it is spare；

S2, appropriate peptide, subtilisin, garlic oil, borneol, Thymol, eugenol, Cineole, menthol, lemongrass are taken Essential oil, palchouli oil, surfactant, cosurfactant, are mixed evenly, spare；

S3, step S1 and the finally obtained solution of step S2 are mixed evenly and are put into high-pressure homogeneous instrument, grain is prepared Diameter is the nano-emulsion of 10~100 nm.

5. farm according to claim 1 disinfecting, deodorizing nanoemulsion, which is characterized in that the surfactant is Stearic acid sodium, potassium oleate, lauryl sodium sulfate, calcium stearate, polyglycereol stearate, polyglycereol olein, sapn (20, 40,60,80), polyoxyethylene fatty acid ester (45,49,52), ethoxylated dodecyl alcohol (30,35) poloxamer, tween (20, 40,60,80), Arabic gum, tragacanth, gelatin, apricot glue, one of cholesterol or a variety of.

6. farm according to claim 1 disinfecting, deodorizing nanoemulsion, which is characterized in that the cosurfactant For ethyl alcohol, normal propyl alcohol, isopropanol, n-butanol, isobutanol, n-amyl alcohol, isoamyl alcohol, 1- hexanol, 2- hexanol, 1- octanol, sec-n-octyl alcohol, One of fusel oil, n nonylphenol are a variety of.

7. farm according to claim 1 disinfecting, deodorizing nanoemulsion, which is characterized in that the nanoemulsion The application of disinfection and deodorization in livestock and poultry cultivation place.

Technical field

The present invention relates to a kind of livestock and poultry cultivation field more particularly to a kind of farm disinfecting, deodorizing nanoemulsions.

Background technique

In recent years, as the shortening of culture-cycle, cultivation density improve, it is high-incidence to result in livestock and poultry.Not only to cultivation Industry brings biggish economic loss, more seriously threatens food safety and human health.Only effectively prevention, just can be reduced hair Disease and death.Disinfection is the key link for implementing the important measures puted prevention first and all kinds of livestock and poultries of prevention and control.Many diseases Disease is precisely due to sterilizing lack of standardization and being not thorough caused.Animal husbandry stench is grown place mainly from the fecaluria of animal and poultry and is rushed Wash waste water, fresh poultry, livestock waste physico-chemical property and odorant, the air pollutants distributed especially stink often makes Complained at neighbouring neighbouring residents from villages and towns, cause the puzzlement of resident, livestock-raising field and government bodies, the staff of farm by Evil is more so.

Livestock and poultry farm disinfection should mainly around feeding, drinking-water, air, poultry house, production district, vehicle apparatus, personnel, Waste, sewage, animal carcass etc. carry out.Selection disinfectant should follow the original of " efficient, safe and stable, economic, conveniently " Then.Selected disinfectant should have powerful sterilization and ability of killing the virus；Safety non-toxic and residual, irritation is small, nothing Special stink and color；The validity period of medicament is long and stablizes, with other disinfectants without incompatibility；It is cheap, user Just, it is easy to get；Deodorizing effect should rapidly effectively, and effect is lasting.

Summary of the invention

Low in cost, easy to operate and agents useful for same toxicity that the purpose of the present invention is to provide a kind of preparation methods compared with It is small, it is lower to the body harm degree of producers, be conducive to safety in production and environmental protection, meanwhile, disinfecting, deodorizing nano-emulsion Agent has the ability of extremely strong killing bacterium and virus, and broad-spectrum high efficacy, can effectively remove cultivation place peculiar smell, has long-term Bacteriostasis；Farm safe and free of toxic and side effects disinfecting, deodorizing nanoemulsion.

The present invention is realized by following measure:

A kind of farm's disinfecting, deodorizing nanoemulsion, which is characterized in that the nanoemulsion includes effective component and auxiliary material, institute Stating effective component includes 1-30 parts of polyhexamethylene guanide or 1-30 parts of poly (hexamethylene) class, and the effective component further includes contracting 1-25 parts of propylhomoserin, 1-25 parts of subtilisin, 1-15 parts of garlic oil, 1-15 parts of borneol, 1-15 parts of Thymol, eugenol 1-10 Part, 1-10 parts of Cineole, 1-10 parts of menthol, 1-10 parts of oil of Cymbopogon winterianus, 1-10 parts of palchouli oil, the auxiliary material includes surface-active 5-20 parts of agent, 1-20 parts of cosurfactant, 5-20 parts of water for pharmaceutical purposes.

Specific feature of the invention is also:

The nanoemulsion includes effective component and auxiliary material, and the effective component includes 15 parts of polyhexamethylene guanide, described effective Ingredient further include 17 parts of peptide, 16 parts of subtilisin, 8 parts of garlic oil, 7 parts of borneol, 7 parts of Thymol, 6 parts of eugenol, 7 parts of Cineole, 8 parts of menthol, 6 parts of oil of Cymbopogon winterianus, 6 parts of palchouli oil, the auxiliary material include 13 parts of surfactant, help surface living 14 parts of agent, 14 parts of water for pharmaceutical purposes of property.

The nanoemulsion includes effective component and auxiliary material, and the effective component includes 10 parts of poly (hexamethylene) class, The effective component further includes 13 parts of peptide, 12 parts of subtilisin, 5 parts of garlic oil, 6 parts of borneol, 5 parts of Thymol, fourth 4 parts of fragrant phenol, 6 parts of Cineole, 4 parts of menthol, 3 parts of oil of Cymbopogon winterianus, 5 parts of palchouli oil, the auxiliary material include 11 parts of surfactant, 8 parts of cosurfactant, 13 parts of water for pharmaceutical purposes.

The nanoemulsion is manufactured as follows:

S1, appropriate polyhexamethylene guanide or poly (hexamethylene) class is taken to be dissolved in water for pharmaceutical purposes, it is spare；

S2, appropriate peptide, subtilisin, garlic oil, borneol, Thymol, eugenol, Cineole, menthol, lemongrass are taken Essential oil, palchouli oil, surfactant, cosurfactant, are mixed evenly, spare；

S3, step S1 and the finally obtained solution of step S2 are mixed evenly and are put into high-pressure homogeneous instrument, grain is prepared Diameter is the nano-emulsion of 10~100 nm.

The surfactant is stearic acid sodium, potassium oleate, lauryl sodium sulfate, calcium stearate, polyglycereol stearic acid Rouge, polyglycereol olein, sapn (20,40,60,80), polyoxyethylene fatty acid ester (45,49,52), ethoxylated dodecyl alcohol (30,35) poloxamer, tween (20,40,60,80), Arabic gum, tragacanth, gelatin, apricot glue, one in cholesterol Kind is a variety of.

The cosurfactant be ethyl alcohol, normal propyl alcohol, isopropanol, n-butanol, isobutanol, n-amyl alcohol, isoamyl alcohol, 1- oneself One of alcohol, 2- hexanol, 1- octanol, sec-n-octyl alcohol, fusel oil, n nonylphenol are a variety of.

The nanoemulsion is in the application of disinfection and deodorization in livestock and poultry cultivation place.

The invention has the benefit that the preparation method of disinfecting, deodorizing nanoemulsion of the present invention it is low in cost, it is easy to operate, And agents useful for same toxicity is smaller, lower to the body harm degree of producers, is conducive to safety in production and environmental protection, together When, disinfecting, deodorizing nanoemulsion has the ability of extremely strong killing bacterium and virus, cultivation place peculiar smell can be effectively removed, and Broad-spectrum high efficacy has long-term bacteriostasis；It is safe and free of toxic and side effects.

Specific embodiment

In order to clarify the technical characteristics of the invention, being illustrated below by specific embodiment to this programme.