A kind of promotion skin tissue repair material film

文档序号:1749111 发布日期:2019-11-29 浏览:20次 中文

阅读说明:本技术 一种促进皮肤组织修复材料膜 (A kind of promotion skin tissue repair material film ) 是由 孙文祥 于 2019-08-21 设计创作,主要内容包括:本发明公开了一种促进皮肤组织修复材料膜,包括纤维纺丝非织造膜、经编间隔织膜、甲壳素敷料层和丝素蛋白敷料层;纺丝非织造膜、经编间隔织膜、甲壳素敷料层和丝素蛋白敷料层从内向外依次层叠设置;经编间隔织膜由超细旦PLA纤维纱线编织而成的薄膜状经编间隔织物;纤维纺丝非织造膜由海藻纤维纺制而成的非织造薄膜;甲壳素敷料层由甲壳素纤维纺丝液静电纺丝而成的非织造膜层结构;丝素蛋白敷料层由丝素蛋白纺丝液静电纺丝而成的非织造膜层结构。本发明采用生物可降解材料制成的复合材料膜,结构强度好,具有良好的生物相容性,触感柔软,贴覆在皮肤伤口表面,保湿透气性好,能够抗菌消炎,促进皮肤组织加速痊愈,使用效果好。(The invention discloses a kind of promotion skin tissue repair material films, including fibre spinning nowoven membrane, warp-knitted spacer to knit film, chitin dressing layer and fibroin albumen dressing layer;Spunlaid nonwoven film, warp-knitted spacer knit film, chitin dressing layer and fibroin albumen dressing layer and are cascading from inside to outside;Warp-knitted spacer knits film film-form warp-knitted spacer fabric as made of the braiding of super fine denier PLA fiber yarn;Nonwoven membrane made of fibre spinning nowoven membrane is spinned as alginate fibre;Chitin dressing layer non-woven film layer structure as made of chitin fiber spinning solution electrostatic spinning;Fibroin albumen dressing layer non-woven film layer structure as made of fibroin albumen spinning solution electrostatic spinning.For the present invention using composite material film made of biodegradable material, structural strength is good, has a good biocompatibility, soft-touch, is covered in skin wound surface, moisturizing good permeability, can antibacterial anti-inflammatory, promote skin histology to accelerate recovery from illness, using effect is good.)

1. a kind of promotion skin tissue repair material film, which is characterized in that knitted including fibre spinning nowoven membrane, warp-knitted spacer Film, chitin dressing layer and fibroin albumen dressing layer;The spunlaid nonwoven film, warp-knitted spacer knit film, chitin dressing layer and Fibroin albumen dressing layer is cascading from inside to outside;The warp-knitted spacer knit film by super fine denier PLA fiber yarn braiding and At film-form warp-knitted spacer fabric;The fibre spinning nowoven membrane uses electrostatic spinning between the warp knit by alginate fibre The nonwoven membrane made of knitting film surface and spinning;The chitin dressing layer is by chitin fiber spinning solution between the warp knit Every knitting non-woven film layer structure made of film surface electrostatic spinning;The fibroin albumen dressing layer is by fibroin albumen spinning solution in institute State non-woven film layer structure made of chitin dressing layer surface electrostatic spinning.

2. promotion skin tissue repair material film according to claim 1, which is characterized in that the super fine denier PLA fiber Yarn is formed by nanometer PLA fiber spinning.

3. promotion skin tissue repair material film according to claim 1, which is characterized in that the warp-knitted spacer knits film With a thickness of 0.12-0.25mm.

4. promotion skin tissue repair material film according to claim 3, which is characterized in that the fibre spinning is non-woven Film with a thickness of 0.05-0.10mm.

5. promotion skin tissue repair material film according to claim 4, which is characterized in that the fibre spinning is non-woven Honeycomb hole is densely covered with inside film.

6. promotion skin tissue repair material film according to claim 5, which is characterized in that knit the fibre spinning is non- The outer surface for making film is compounded with polytetrafluorethylenano nano film layer.

Technical field

The present invention relates to biological medicine field of textiles, in particular to a kind of promotion skin tissue repair material film.

Background technique

Organizational project is that the cell seeding of cultured and amplified in vitro and a kind of biocompatibility is good and has certain space On the biomaterial of structure, culture makes cell mass propagation in vitro, then by their co-transplantations in required position, in body Inner cell continues to be proliferated, and biological support structure is then gradually degraded and absorbed, and as a result forms new histoorgan, to reach group Knit the purpose of reparation.Therefore, selecting suitable biomaterial and preparation method to construct tissue engineering bracket is Tissue Engineering Study Basis.Electrostatic spinning be it is a kind of formed under forceful electric power field action using polymer solution or melt injection stream carry out spinning processing Technique.Since electrostatic spinning technique is capable of forming nanometer to micron order fiber, the Nomenclature Composition and Structure of Complexes of extracellular matrix is imitated, is Cell provides good growing environment, therefore is the ideal method for preparing tissue engineering bracket.

Fibroin albumen is a kind of natural polymer fibrin, has nontoxic, biodegradable, good biocompatibility etc. Performance is suitable for bio-sensing, drug release material, the application fields such as tissue engineering material.Independent electrostatic spinning fibroin is It has been reported that, but pure silk cellulosic material has biggish brittleness, the inadequate disadvantage of mechanical strength hinders it in tissue engineering material side The research and application in face.Therefore, a kind of NEW TYPE OF COMPOSITE textile fabric film for promoting skin histology reparation of demand.

Summary of the invention

In order to solve the above technical problems, the present invention provides a kind of promotion skin tissue repair material films, using between warp knit Every knitting film as basement membrane, by MULTILAYER COMPOSITE, solve that single fibroin albumen nowoven membrane brittleness is big, mechanical strength is inadequate Problem.

In order to achieve the above objectives, technical scheme is as follows: a kind of promotion skin tissue repair material film, including fibre Dimension spunlaid nonwoven film, warp-knitted spacer knit film, chitin dressing layer and fibroin albumen dressing layer;The spunlaid nonwoven film, warp It knits film, chitin dressing layer and fibroin albumen dressing layer and is cascading from inside to outside in volume interval;The warp-knitted spacer knits film The film-form warp-knitted spacer fabric as made of the braiding of super fine denier PLA fiber yarn;The fibre spinning nowoven membrane is by seaweed fibre Dimension nonwoven membrane made of electrostatic spinning knits film surface spinning in the warp-knitted spacer;The chitin dressing layer is by first Shell cellulose fiber spinning solution knits non-woven film layer structure made of film surface electrostatic spinning in the warp-knitted spacer;The fibroin albumen Dressing layer is as fibroin albumen spinning solution non-woven film layer structure made of the chitin dressing layer surface electrostatic spinning.

As a preferred solution of the present invention, the super fine denier PLA fiber yarn is formed by nanometer PLA fiber spinning.

As a preferred solution of the present invention, the warp-knitted spacer knit film with a thickness of 0.12-0.25mm.

As a preferred solution of the present invention, the fibre spinning nowoven membrane with a thickness of 0.05-0.10mm.

As a preferred solution of the present invention, honeycomb hole is densely covered with inside the fibre spinning nowoven membrane.

As a preferred solution of the present invention, polytetrafluoroethyl-ne is compounded in the outer surface of the fibre spinning nowoven membrane Alkene nanometer film layer.

Through the above technical solutions, the beneficial effect of technical solution of the present invention is: structure of the invention is reasonable, can using biology Composite material film made of degradable material, structural strength is good, has good biocompatibility, and soft-touch is covered in skin Wound surface, moisturizing good permeability, can antibacterial anti-inflammatory, promote skin histology to accelerate recovery from illness, using effect is good.

Detailed description of the invention

In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with It obtains other drawings based on these drawings.

Fig. 1 is the structural schematic diagram in section of the present invention.

Number and corresponding component title represented by letter in figure:

1. 2. warp-knitted spacer of fibre spinning nowoven membrane knits 3. chitin dressing layer of film, 4. fibroin albumen dressing layer.

Specific embodiment

Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.

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