阅读说明：本技术 害虫防治混合物 (Pest control mixture ) 是由 A.多坦 T.达农 于 2013-11-05 设计创作，主要内容包括：本申请涉及害虫防治混合物。本申请涉及杀虫混合物,其包括(a)乙基多杀菌素；和(b)选自双苯氟脲、吡丙醚、氟胺氰菊酯及其组合的组A化合物。(The present application relates to pest control mixtures. The present application relates to pesticidal mixtures comprising (a) spinetoram; and (b) a compound selected from group a of novaluron, pyriproxyfen, cyfluthrin, and combinations thereof.)

1. A pesticidal mixture comprising:

(a) spinetoram; and

(b) a compound of group a selected from novaluron, pyriproxyfen, cyfluthrin, and combinations thereof.

2. The pesticidal mixture according to claim 1, wherein the weight ratio of spinetoram to the compound of group a is from 1:100 to 100: 1.

3. The pesticidal mixture according to claim 1, wherein the weight ratio of spinetoram to the compound of group a is from 1:10 to 10: 1.

4. The pesticidal mixture according to any one of claims 1 to 3, wherein spinetoram is applied in an amount of from 1 g/ha to 500 g/ha.

5. The pesticidal mixtures according to any of claims 1 to 4, wherein the application rate of the group A compounds is from 1 g/ha to 500 g/ha.

6. A synergistically effective amount of the pesticidal mixture of any one of claims 1 to 5.

7. A pesticidal composition comprising the pesticidal mixture according to any one of claims 1 to 6; and an agriculturally acceptable carrier.

8. The pesticidal composition according to claim 7, for controlling pests in crops or their locus.

9. A method of controlling pests in a crop, the method comprising:

contacting a pest or a locus where pest control is desired with a pesticidal mixture comprising:

(a) spinetoram; and

(b) a compound of group a selected from novaluron, pyriproxyfen, cyfluthrin, and combinations thereof.

10. The method of claim 9, wherein the weight ratio of spinetoram to group a compound is from 1:100 to 100: 1.

11. The method according to claim 9 or 10, wherein the weight ratio of spinetoram to group a compound is from 1:10 to 10: 1.

12. The method according to any one of claims 9 to 11 wherein spinetoram is applied in an amount of from 1 g/ha to 500 g/ha.

13. A method according to any one of claims 9 to 12 wherein the amount of the compound of group a administered is from 1 g/ha to 500 g/ha.

14. A method according to any one of claims 9 to 13, wherein the amount of pesticidal mixture according to claim 9 applied is from 1 g/ha to 1000 g/ha.

15. The method according to any one of claims 9 to 14, wherein spinetoram and the compound of group a are applied concomitantly or sequentially.

16. A kit comprising (a) at least one container comprising spinetoram; (b) at least one container comprising a compound of group a selected from novaluron, pyriproxyfen, tau-fluvalinate, and combinations thereof; and (c) instructions for applying said spinetoram and said group A compound to a pest or to a locus where control of a pest is desired.

17. The kit of claim 16 wherein said spinetoram and said group a compound are applied concomitantly or sequentially.

18. A kit comprising (a) at least one container comprising (i) spinetoram; and (ii) a compound of group a selected from novaluron, pyriproxyfen, cyfluthrin, and combinations thereof; and (b) instructions for applying said spinetoram and said group A compound to a pest or to a locus where control of a pest is desired.

Technical Field

The present disclosure relates to pesticidal mixtures for pest control.

Background

Active agent mixtures are described in the literature. However, the control of pests does not always meet the needs of agricultural practice. In addition, the efficacy of the mixtures is not entirely satisfactory in the field of pest control and/or toxicological and/or environmental effects.

Spinetoram (spinetoram) is a semi-synthetic spinosyn. The spinetoram is 50-90% (2)R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR) -2- (6-deoxy-3-)O-ethyl-2, 4-bis-O-methyl-alpha-L-mannopyranosyl) -13- [ (2R,5S,6R) -5- (dimethylamino) tetrahydro-6-methylpyran-2-yloxy]-9-ethyl-2, 3,3a,4,5,5a,5b,6,9,10,11,12,13,14,16a,16 b-hexadecahydro-14-methyl-1H-as-indenopheno (indaceno) [3, 2-)d]Oxacyclohexaene (oxacyclohexadecine) -7, 15-dione and 50-10% (2)S,3aR,5aS,5bS,9S,13S,14R,16aS,16bS) -2- (6-deoxy-3-)O-ethyl-2, 4-bis-O-methyl-alpha-L-mannopyranosyl) -13- [ (2R,5S,6R) -5- (dimethylamino) tetrahydro-6-methylpyran-2-yloxy]-9-ethyl-2, 3,3a,5a,5b,6,9,10,11,12,13,14,16a,16 b-decatetrahydro-4, 14-dimethyl-1H-as-indenopheno (indaceno) [3, 2-)d]A mixture of oxacyclododecane (oxacyclododecane) -7, 15-dione.

["Compendium of Pesticide Common Names" available at:www.alanwood.net/pesticides/index.html]。

Spinetoram has been described in U.S. Pat. No. 6,001,981. Spinetoram is also described in The E-Pesticide Manual (Version 5.0.1, 2010, 15 th edition: CDS Tomlin)), Entry number 783.

Spinetoram: 50-90% of component (i); and 50-10% of component (ii).

Pesticidal mixtures comprising spinosad have been described in WO 2010/052129, WO2010/030501, US 6,444,667, US 6,686,387 and US 2006/0211655.

The pesticidal compositions and mixtures do not exert satisfactory controlling effects in some cases, and therefore there is still a need to develop novel pesticidal mixtures having satisfactory controlling effects.

It would therefore be highly advantageous to provide novel pesticidal mixtures of spinetoram with very good control of various pests, improved control of pests, a broadened control spectrum and/or maintenance of a favourable and reduced environmental or toxicological effect, in combination with the various pesticides described in the present invention.

Disclosure of Invention

Summary of The Invention

According to one aspect, there is provided a pesticidal mixture comprising (a) spinetoram; and (b) a compound selected from the group a consisting of novaluron (novaluron), pyriproxyfen (pyriproxyfen), tau-fluvalinate (tau-fluvalinate), and combinations thereof.

According to another aspect, there is provided a pesticidal composition comprising a pesticidal mixture comprising (a) spinetoram; and (b) a compound selected from group a of novaluron, pyriproxyfen, cyfluthrin, and combinations thereof.

According to another aspect, there is provided a method of controlling pests in crops, the method comprising contacting the pests or a locus where pest control is desired (locus) with a pesticidal mixture comprising (a) spinetoram; and (b) a compound selected from group a of novaluron, pyriproxyfen, cyfluthrin, and combinations thereof.

According to another aspect, a kit is provided comprising (a) at least one container comprising spinetoram; (b) at least one container comprising a compound of group a selected from novaluron, pyriproxyfen, tau-fluvalinate, and combinations thereof; and (c) instructions for applying said spinetoram and said group A compound to a pest or to a locus where control of a pest is desired.

According to yet another aspect, a kit is provided comprising (a) at least one container comprising (i) spinetoram; and (ii) a compound of group a selected from novaluron, pyriproxyfen, cyfluthrin, and combinations thereof; and (b) instructions for applying said spinetoram and said group A compound to a pest or to a locus where control of a pest is desired.

Detailed Description

Before setting forth the invention in detail, it may be helpful to provide definitions for certain terms used herein. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.

The use of the terms "a" and "an" and "the" and similar referents in the context of describing the invention (especially in the context of the following claims) are to be construed to cover both the singular and the plural, unless otherwise indicated herein or clearly contradicted by context.

The term "crop" as used herein includes reference to a whole plant, plant organ (e.g., leaf, stem, twigs, root, trunk, branch, shoot, fruit, etc.), or plant cell.

The term "as used herein"Propagation material"is understood to mean all the reproductive parts of plants, such as seeds and spores, vegetative structures, such as bulbs, corms, tubers, rhizomes (rhizomes), rhizomes (rootstocks), basals shoots (basal shoots), stolons and shoots.

According to one aspect, there is provided a pesticidal mixture comprising (a) spinetoram; and (b) a compound selected from group a of novaluron, pyriproxyfen, cyfluthrin, and combinations thereof.

The spinetoram is 50-90% (2)R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR) -2- (6-deoxy-3-)O-ethyl-2, 4-bis-O-methyl-alpha-L-mannopyranosyl) -13- [ (2R,5S,6R) -5- (dimethylamino) tetrahydro-6-methylpyran-2-yloxy]-9-ethyl-2, 3,3a,4,5,5a,5b,69,10,11,12,13,14,16a,16 b-hexadecahydro-14-methyl-1H-as-indenopheno (indaceno) [3, 2-)d]Oxacyclohexaene (oxacyclohexadecine) -7, 15-dione and 50-10% (2)S,3aR,5aS,5bS,9S,13S,14R,16aS,16bS) -2- (6-deoxy-3-)O-ethyl-2, 4-bis-O-methyl-alpha-L-mannopyranosyl) -13- [ (2R,5S,6R) -5- (dimethylamino) tetrahydro-6-methylpyran-2-yloxy]-9-ethyl-2, 3,3a,5a,5b,6,9,10,11,12,13,14,16a,16 b-decatetrahydro-4, 14-dimethyl-1H-as-indenopheno (indaceno) [3, 2-)d]A mixture of oxacyclododecane (oxacyclododecane) -7, 15-dione.

["Compendium of Pesticide Common Names" available at:www.alanwood.net/pesticides/index.html]。

Spinetoram is described in The E-Pesticide Manual (Version 5.0.1, 2010, 15 th edition: CDS Tomlin)), Entry number 783.

Spinetoram: 50-90% of component (i); and 50-10% of component (ii).

Diphenylfluorouracil ((. + -.) -1- [ 3-chloro-4- (1,1, 2-trifluoro-2-trifluoromethoxyethoxy) phenyl ] -3- (2, 6-difluorobenzoyl) urea) is described in The E-Pesticide Manual (Version 5.0.1, 2010, 15 th edition: CDS Tomlin)), Entry number 621

。

Cyfluthrin ((R) (Version 5.0.1, 2010, 15 th edition: CDS Tomlin)) Entry number 423 is described in The E-Pesticide Manual (Version 5.0.1, 2010, 15 th edition)RS)-N- (2-chloro-alpha, alpha-trifluoro-p-tolyl) -D-valine α -cyano-3-phenoxybenzyl ester

，

Pyriproxyfen (4-phenoxyphenyl: (4-phenoxyphenyl)) is also described in The E-Pesticide Manual (Version 5.0.1, 2010, 15 th edition: CDS Tomlin)) Entry number 749RS) -2- (2-pyridyloxy) propyl ether)

。

These compounds are also described in the "Complex of Pesticide Common Names" available from www.alanwood.net/pesticides/index. html。

According to another aspect, there is provided a pesticidal composition comprising a pesticidal mixture as described in the present disclosure; and an agriculturally acceptable carrier.

According to certain embodiments, the pesticidal mixtures may bring about synergistic pesticidal activity when applied to pests.

The synergistic effect may be calculated as described in an article entitled "stabilizing synthetic and anti-inflammatory responses of pharmaceutical compositions" disclosed in the journal Weeds, 1967, 15, pages 20-22, which is incorporated herein by reference in its entirety, by Colby s.

The pesticidal composition comprising the mixture as described in the present disclosure may improve the efficacy of pesticidal activity, may broaden the control spectrum and/or may minimize the dosage of active ingredients used, compared to the use of such individual pesticides alone.

According to a particular embodiment, the pest is selected from the group consisting of insects, mites, mollusks or combinations thereof.

In a particular embodiment, the pest is an insect. In a particular embodiment, the pest is a mite. In a particular embodiment, the pest is a mollusk.

The term "insecticidal" especially relates to insecticidal and/or acaricidal activity. The term "pesticidal" also relates to molluscicidal activity.

According to another aspect, there is provided a synergistic pesticidal mixture comprising (a) spinetoram; and (b) a compound selected from group a of novaluron, pyriproxyfen, cyfluthrin, and combinations thereof.

According to another aspect, there is provided a pesticidal composition comprising a synergistically effective amount of a pesticidal mixture as described in the present disclosure; and an agriculturally acceptable carrier.

The compositions are useful for controlling agricultural pests in crops or their locus comprising contacting the agricultural pest or a food supply, habitat or locus of the agricultural pest with an effective amount of a mixture as described in the present disclosure.

According to another aspect, there is provided a method of controlling pests in crops comprising contacting the pests or the locus where control of the pests is desired with a pesticidal mixture comprising (a) spinetoram; and (b) a compound selected from group a of novaluron, pyriproxyfen, cyfluthrin, and combinations thereof.

According to another aspect, there is provided a method of controlling pests in crops comprising contacting the pests or the locus where control of the pests is desired with a composition comprising a pesticidal mixture as described in the present disclosure.

The locus may be soil or water in which the crop is growing.

The present disclosure further relates to a method of controlling pests in crops or propagation material thereof, comprising contacting a food supply, habitat, breeding ground or locus of the pests or agricultural pests with an amount of a combination of pesticidal mixtures as described in the present disclosure.

According to certain embodiments, the weight ratio of spinetoram to the compound of group a selected from novaluron, pyriproxyfen, cyfluthrin, and combinations thereof is from 1:1000 to 1000: 1. In one embodiment, the weight ratio of spinetoram to group a compound is from 1:100 to 100: 1. In another embodiment, the weight ratio of spinetoram to the group a compound is from 1:50 to 50: 1. In yet another embodiment, the weight ratio of spinetoram to the group a compound is from 1:10 to 10: 1. In another embodiment, the weight ratio of spinetoram to the group a compound is from 1:8 to 8: 1. In another embodiment, the weight ratio of spinetoram to the group a compound is from 1:5 to 5: 1.

According to some embodiments, the weight ratio of spinetoram to the compound of group a selected from novaluron, pyriproxyfen, cyfluthrin, and combinations thereof is 100:1 and less, 50:1 and less, 10:1 and less, 8:1 and less, 5:1 and less, 4:1 and less, 3:1 and less, 2:1 and less, 1.3: 1 and less, 1:1 and less.

According to some embodiments, the weight ratio of spinetoram to the compound of group a selected from novaluron, pyriproxyfen, cyfluthrin, and combinations thereof is 1:100 and higher, 1:50 and higher, 1:10 and higher, 1:8 and higher, 1:5 and higher, 1:4 and higher, 1:3 and higher, 1:2 and higher, 1:1.3 and higher, 1:1 and higher.

The weight ratio of spinetoram to the compound of group a selected from novaluron, pyriproxyfen, cyfluthrin, and combinations thereof can be within a range between any of the foregoing indicated values (e.g., 4:1 to 1:4, 4:1 to 1:3, 4:1 to 1:2, 4:1 to 1:1.3, 4:1 to 1:1, 3:1 to 1:4, etc.).

The term "as used herein"ha”This is a hectare.

According to certain embodiments, the amount of spinetoram applied is from 0.5 grams per hectare ("g/ha") to 500 g/ha, particularly from 1 g/ha to 250 g/ha, more particularly from 1 g/ha to 100 g/ha.

According to certain embodiments, the amount of spinetoram applied is 0.5 g/ha and greater, 1 g/ha and greater, 1.5 g/ha and greater, 2 g/ha and greater, 2.5 g/ha and greater, 3 g/ha and greater, 3.5 g/ha and greater, 4 g/ha and greater, 4.5 g/ha and greater, 5 g/ha and greater, 5.5 g/ha and greater, 6 g/ha and greater.

According to certain embodiments, the amount of spinetoram applied is 500 g/ha and less, 250 g/ha and less, 200 g/ha and less, 150 g/ha and less, 100 g/ha and less, 50 g/ha and less, 20 g/ha and less, 10 g/ha and less, 8 g/ha and less.

The amount of spinetoram applied can be in any range between any of the above indicated values.

According to certain embodiments, the compounds of group A are applied in an amount of from 0.5 g/ha to 500 g/ha, especially from 1 g/ha to 250 g/ha, more especially from 1 g/ha to 100 g/ha.

According to certain embodiments, the compounds of group A are administered at an amount of 0.5 g/ha and greater, 1 g/ha and greater, 1.5 g/ha and greater, 2 g/ha and greater, 2.5 g/ha and greater, 3 g/ha and greater, 3.5 g/ha and greater, 4 g/ha and greater, 4.5 g/ha and greater, 5 g/ha and greater, 5.5 g/ha and greater, 6 g/ha and greater.

According to certain embodiments, the amount of a compound of group A administered is 500 g/ha and less, 250 g/ha and less, 200 g/ha and less, 150 g/ha and less, 100 g/ha and less, 50 g/ha and less, 20 g/ha and less, 10 g/ha and less, 8 g/ha and less.

The amount of the group a compound selected from novaluron, pyriproxyfen, cyfluthrin to be applied may be in any range between any of the indicated values.

According to certain embodiments, the pesticidal mixtures as described in the present disclosure are applied in an amount of from 1 g/ha to 1000 g/ha. In a specific embodiment, the amount of pesticidal mixture as described in this disclosure applied is from 2 g/ha to 1000 g/ha.

In another embodiment, the combination (mixture) of spinetoram and a compound of group A is applied in an amount from 1 g/ha to 500 g/ha. In yet another embodiment, the combination of spinetoram and a compound of group A is applied in an amount from 1 g/ha to 250 g/ha. In yet another embodiment, the combination of spinetoram and a compound of group A is applied in an amount from 1 g/ha to 200 g/ha. In yet another embodiment, the combination of spinetoram and a compound of group A is applied in an amount from 1 g/ha to 150 g/ha. In yet another embodiment, the combination of spinetoram and a compound of group A is applied in an amount from 1 g/ha to 100 g/ha. In yet another embodiment, the combination of spinetoram and a compound of group A is applied in an amount from 1 g/ha to 50 g/ha. The above ranges refer to the amount of spinetoram and the combination of group a compounds applied (i.e., the sum of the amounts of the two active ingredients applied).

In one embodiment, spinetoram and the group a compound are administered concomitantly (concatantly) or sequentially.

Spinetoram and the group a compound can be applied in any desired order.

The term "sequential application" refers to sequential application of compositions comprising spinetoram, followed by application of a composition of the compound of group a. When applied sequentially, spinetoram and the group a compound are included in separate compositions. If spinetoram and the compound of group A are applied sequentially, the order of their application can be interchanged.

The term "simultaneous administration" or "concomitant administration" refers to the administration of these compounds at substantially the same time. These terms include not only the application of the spinetoram and group a compounds of the present invention in a single formulation (composition), but also the application of each compound (i.e., spinetoram and group a compounds) in its own separate formulation. When separate formulations are used, the compounds may be administered substantially simultaneously, i.e., concurrently.

The application may be by any method known in the art, in particular by methods such as spraying, dipping, dusting, dressing (drenching), coating and soaking.

The present disclosure further relates to the use of a composition comprising a pesticidal mixture as described in the present disclosure for controlling pests in crops or their locus.

The present disclosure also relates to compositions comprising the pesticidal mixtures as described in the present disclosure for controlling pests in crops or their locus.

In one embodiment, the pesticidal mixture is in a synergistically effective amount.

Such crops include, but are not limited to, vegetables, fruits, soybeans, tobacco, cultivated mushrooms, cotton, oilseed rape, cereals, sunflowers, peanuts, rice, corn, coffee, beans, peas, yucca, sugar cane, alfalfa, spice crops, ornamentals, cocoa, sugar beet.

In one embodiment, the crop may be a vegetable, such as pepper, cabbage, cauliflower, asparagus, artichoke, pumpkin (squash), lettuce, turnip, spinach, cauliflower, melon, watermelon, cucumber, carrot, onion, garlic, gourd, and potato; fruits, such as pomes and stone and berries, e.g. walnuts, kiwifruits, bananas, avocados, olives, passion fruits, apricots, pineapples, pears, plums, peaches and cherries, tropical and subtropical fruits, food grapes and wine grapes, citrus fruits, such as oranges, lemons, grapefruits and limes; cereals, such as wheat, barley, rye, triticale, oats, sorghum; corn (maize), such as sweet corn; beets, such as sugar beet, fodder beet; spice crops such as cardamom; ornamental plants, such as flowers and christmas trees.

In another embodiment, the insect pest is Coleoptera (Coleoptera), such as the genus tridentate bean (Acanthoscelides spp), weevil (weevil), phaseolus vulgaris (Acanthoscelides obtectus) (common weevil), white cerifera (agrius planipennis) (emerald borer), click beetle (Agriotes spp), athetia glabrata (anophora glabripennis) (asian longissima), anthurium (anthurius p.) (elephantopus), gossypium mexicanum (athrominus grandis) (Apocynaceae), gossypium hirsutum (gossypium hirsutum), hornworthia (aphyllus spp.), small beak weevil (apium napus) (elephantopus), nasturpinus nasalis (paragonis), hornea (Black beetle), pisifera species (grunus sp.), or pisifera species (grunus sp.), small beak weevil (elephantopus purpurea), piss (grus purpurea), piss (grus purpurea), piss purpurea species (grub weevils), piss (pacifia purpurea) or piss (pacifica), piss (piss) or piss purpurea) or piss (piss) or piss (pisifera) or pisifera species (pisifera) or pisifera (pisifera species (pisifera) or pisifera species (pisifera) or pisifera species (pisifera) or pisifera (pisifera) or a species (pisifera) or a (pisifera) or pisifera species (pisifera) or pisifera (pisifera) or a species (pisifera) or pisifera species (pisifera species (pisifera) or a species (pisifera) or pisifera species (pisifera) or a species (pisifera) or a (pisifera) or a) or pisifera species (pisifera) or a species (pisifera) or pisifera species (pisifera) or a species (pisifera) or a species (pis, Cacoes spp, calophyllus maculatus (calophyllus), tortoise shell (Cassida vittata), cerasterna spp, Cerotoma spp (leaf beetles), bean leaf beetle (bean leaf beetles), tortoise (cerotophycus spp) (weevil), Chinese cabbage turtle (cerotophycus assilippinis) (cabbage weevil), cerotophycus napi (turnip weevil), concave shank beetle (chaetophycus spp) (leaf beetles), coloraspis spp (soil beetle), conoderis, consortius maculatus (conotosus), corn stinus maculatus (corn beetles), corn beetle (corn beetle) and corn beetle (corn beetle) or corn beetle (corn beetle), corn beetle larva (corn beetle) or corn beetle spilus (corn beetle), corn beetle spilus spp (corn beetle) or corn beetle (corn beetle) may be used in the corn beetle, corn beetle spis, corn beetle (corn beetle, corn beetle spis, corn beetle (corn beetle, corn beetle spis (corn beetle, corn beetle, Deporaus marginata (mango leaf cutting elephant), Dermestes laderius (ham bark beetle), Dermestes maculomes (bark beetle), Diabrotica spp (Diabrotica spp.) (phylloxera), Epilachna varivestis (Mexico bean beetle), tobacco borer (Faustinum cubae), Hyperbius pales (Siberian cocklebur.), Leptospira microphylla (Hypera spp.) (weevil), Hypera potticica (purple clover), Hyperodes p (Hyperodes weevil), Hyperthecoides sepheifer (Hyperodes weevil), Hyperthenemus hamipes (coffee berry), Ipiss spp. (enbergs), Lasioderma serricorn (tobacco beetle), Leptothecia degermaria, Melothrix (Mesporea), Melothria spp. (Melothria spp.), Melothria spp (Melothria spp.) (Melothria spp. ) (Melothria spp., Melothria spp.) (Melothrix), Melothria spp.) (Melothrix), Melothrix, Melothria spp.) (Melothrix ), Melothria spp. (Melothrix, Melothria spp. (Melothrix), Melothria spp.) (Melothrix, Melothria spp. (Melothria spp.) (Melothrix) A. sp. (Melothria spp. (Melothrix, Melothria spp. (Melothria spp.) (Melothrix, Melothria spp.) (Melothria spp.) (Melothrix, Melothria spp.) (Melothria spp.) (Melothrix, Melothria spp.) (Melothria spp.) (Melothrix, Melothria spp.) (Melothrix, Melothria spp. (Melothria spp.) (Melothrix, Melothria spp. (Melothrix sp. (Melothrix) A. sp. (Melothrix ) A. sp. (Mel, Oberea breves, Oberea linearis, Oryces rhinoceros (bark palm beetle), Oryzaephilus mercator (large-eyed saw beetle), Oryzaephilus surrinamensis (saw beetle), Otiophycus spp (weevil), Oryza melanosporum (cereal diabrotica), Oryza oryzifolia (Oulema oryzae), Rhynchosia brevicaulis (Pantomus spp.) (weevil), Ceralia spicata (Phyolophlla spp.) (Phomophorus spp.) (Phellophora spp.) (Pentobius), Phyllophora cephalospora (Phyllophora spp.) (Phellophora platyphylla), Phyllophora lepta (bark beetle), Rhynchosporus pisorhizus spp. (Phellophora microphyllus), Rhynchus fasciolophycus spp. (Rhynchophorus spp.) (Rhizophyllus spp.) (Rhynchophorus spp.) (Rhynchos), Rhynchosporus pis pinus pis, Rhynchosporus pisorus pinus (Rhynchophorus), Rhynchosporus pisorus pinus pis pinus spp. (Rhynchosporus spp.) (Rhynchosporus), Rhynchosporus spp.) (Rhynchosporus), Rhynchosporus spp.) (Rhynchosporus pis. sp.) (Rhynchosporus), Rhynchophorus pis), Rhynchos pis pisorus rhynchosta (Rhynchophorus pis), Rhynchos pis (Rhynchos pis), Rhynchopsis), Rhynchos (Rhynchophorus spp. (Rhynchos pis), Rhynchos pis (Rhynchos pis), Rhynchopsis), Rhynchos pis (Rhynchos pis), Rhynchos pis (S), Rhynchopsis), Rhynchos pis (S), Rhynchos pis (Spirostris, Rhynchos pis pisifera), Rhynchos pis (S), Rhynchos pis (S, Rhynchos pis (S), Rhynchos (S, Rhynchopsis), Rhynchos pis (S), Rhynchos pis, Rhynchos pis, Sitophilus oryzae, Stegobium paniceum, Tribolium spp, Tribolium castaneum, Tribolium confugum, Tropaediata, Trogopterus variegatus, and Zabrus tenebrioides.

In a further embodiment, the insect pest is of the order Diptera (Diptera), such as Aedes spp (mosquito), Agromyza frontella (lucerne leaf fly), Agromyza spp (Agromyza spp.), trypanosoma (Agromyza spp.), drosophila (drosophila melanogaster), anastrephea supensia (caribbera), Anopheles spp (mosquito), drosophila (Batrocera spp.), Bactrocera curbitae (melon fly), Bactrocera dorsalis (oriental fruit fly), Ceratitis (Ceratitis spp.), Ceratitis spp (Ceratitis spp.), Ceratitis pitata (medicina), mosla spp (contagiosa spp), Ceratitis spp (deer fly), Ceratitis spp (Ceratitis spp.), Ceratitis spp (Ceratitis spp), Ceratitis mithrata (Ceratitis spp), euglena spp (deer fly), euglena spp) Drosophila (Drosophila spp.) (Vinegar fly), latrine (Fannia spp.) (Musca domestica), Fannia canicicularis (Eisetz. latus), Fannia serviaris (Lagerstroemia griseus), Gasterophilus intestinalis (horse fly), Gracillia perseae, Haematobia irtans (horn fly), Musca (Hylemia spp.) (root maggot), dermomya striatus (Hypodera linetum) (cattle Holotrichia grub), Musca microplus (Liriomyza spp.) (cherry fly), Liriomyza brassica braziana (Musca americana), phasca phaea (Melogus ovinus) (sheep), Musca domestica (Musca autunalis), Musca domestica (Musca), Musca domestica), Musca melanogaster (Musca domestica), Musca domestica (Musca), Musca domestica), Musca (Musca variety (Musca), Musca (Musca domestica), Musca (Musca) and Musca (Musca variety (Musca), Musca) and Musca (Musca domestica), Musca variety (Musca), Musca variety (Musca), Musca variety (Musca, Musca variety (Musca), and Musca variety (Musca), and Musca variety (Musca), and Musca) and Musca variety (Musca variety, Musca) and Musca variety (Musca) and Musca variety (Musca), and Musca variety, Musca variety (Musca variety, Musca variety (Musca variety, Musca) and Musca variety, Musca variety (Musca variety, and Musca) and Musca variety, and their, and, Tabanus (Tabanus spp.) (horse flies) and Aedes (Tipula spp.) (Aedes mosquitoes).

In yet another embodiment, the insect pest is Hemiptera (Hemiptera), such as Acrosternum villosum (Oryza sativa), Blissus leucopterus (Oridophycus), Calocoris norvegicus (potatoMirid), Cimex hemipterus (Tropiceus), Cimex lectularius (Clerodera cinerea), Dichelops melantus (Dallas), Dagbertus fasciatus, Dichelofusus, Dysdercus sutureus (Cotton bugs), Edessa meditalbunda, Eurygaster maura (nuclear bug), Euschistosus bugs, Euschistosus servatus (brown stinkbug), Helopeltis antinii, Helopeltis theovora (tea plant), Laynomus sp.sp.bugs (elephant), Leptosporidium, Allium (Phytocida), Phytocassium spp. coriaria, Phytocytum, Phytocida (Phytocida), Phytocida (Phytocassius), Phytocassius), Phytocassius viridis viridans, Phytocassius, Phytocassia viridis, Phytopsis, Phytophus, Phytocassius, Phytophus viridis, Phymatococcus (Phocidula, Phymatococcus spp. viridis, Phymatodes, Phymatococcus (Phocidula, Phymatococcus (Phocidus), Phymatodes), Phymatococcus (Phoca), Phytocida), Phytocassius), Phymatococcus (Phormis, Phytocassius), Phymatococcus (Phocidus, Phytocassius), Phytocassia, Phytocassius, Phytocassia, Phytocassius, Phytocassia, Phytocassius, Phytocassia, and Phytocassia, Phytocassius, Phytocassia, and Phytocassia, Phymatodes, Phytocassia, Phymato.

In a further embodiment, the insect pest is of the order Homoptera (Homoptera), such as Acrythosiphin pisum (Piper pisum), Coccinum (Adelges spp.) (Globius globulus), Aleurodes prolifera (Belaginella brassicae), Aleurotius spiralis (Aleurodicus dispers), Aleurothrix florius (Trialeurodes palmeriana), Aluaspis spp., Amrasa biguella, Cicada spp. (Aphrophora spp.) (Pediculus flavus), Aoniella aurantianiformis (Lecanicola), Aphis gossypiella (Aphis fabarum), Aphis fabarum (Bectonia solani), Aphis graminis (Bectonia), Mycopharzicola (Bectonia), Mylophora), Mylophaga (Bectonia solani), Mylophaga (Bectona), Mylophaga (Bectona), Mylophagoides, Mylophaga (Bectona), Mylophagoides), Myzus (Bectona brassica (Bectona), Myzus (Bectona), Mylophaga sp. (Bectona), Myzus (Bectona, Myzukii), Myzus (Bectona), Myzukii (Bectona), Myzus (Bemisia), Myzus (Bectona), Myzukii), Myzus (Begonia), Myzus (Bemisia), Myzus (Bemisia), Myzus (Begonia), Myzus (Bemisia), Myzukii), Myzus (Bemisia), Myzus (Bemisia), Myzus, Ceroplastes rubens (Erythrophorus gracilis), Scopidae sp (Chionaspis spp.) (Lecania), Scopidae coccinella (Chrysomophagus spp.) (Lecanis coccinella), Coccus spp. (Lecanis), Dysaphis plantaginea (Rose apple aphid), Empoasca spp. (leaf hoppers), Eriosoma lanigerum (apple aphid), Icerya purchasi (Blastomyces insufflatus), Idioscope nitidus (mango leaf hoppers), Laodelphax striatellus (small brown plant louse), oyster louse (Lepidosaphus spp.), Phyllophora elongata (large leaf aphid), Mylophora grandis (leaf hopper), Mylophora grandiflora (leaf aphid), Mycophyllum eurotium (leaf aphid grandiflora), Mycophyllum euroticum (leaf aphid), Mylophora grandiflora (leaf aphid grandis), Mylophora grandiflora (leaf aphid (leaf), Mylophora grandiflora), Mylophora grandis (leaf), Mylophora grandis (leaf aphid (Missima grandis), Mylophora grandis (leaf aphid (Miphos grandis), Mylophora (Missium), Mylophora grandis), Mylophora (Missium grandis (Missium), Mylophora grandis (Missium grandis), Mylophora grandis (Missium, Mylophora (Missium, Mylophora grandis), Mylophora grandis (Missium, Mylophora (Missium grandis (Missium, Mylophora) and Mycelosissium, Mylophora (Missium, Mylophora grandis), Mylophora (Missium) and Mylophora (Missium), Mylophora grandis (Missium) and Mylophora grandis), Mylophilus) and Mylophilus (Missium grandis), Mylophium (Miphos grandis (Missium grandis), Mylophium (Missium (Mitsu) et Mitsuba) et Mitsu (Mitsu grandis (Mitsuba) and Mylophium (Mitsuba) and Mycelastrum (Mitsuba) et Mitsuba, Mycelius), Mylophium (Mitsuba, Mylophii (Mitsuba, Mylophium grandis), Myxophysum (Mitsuba, Myxophynum), Mylophium grandis), Mylophium (Mitsuba, Mylophium (Mitsu grandis), Mylophium (Mitsuba, Myxophys), Mylophii (Mitsuba, Myxophys (Mitsu (Mitsuba, Myxophys (Mitsu, Lawsonia genus (Philaenus spp.) (Lawsonia melanostictus), Phylloxera vitifolia (Rhixomatococcus auratus), Physokermes piceae (Ceratococcus yunnanensis), Phyllococcus sp. (Lecanis pelykii), Phyllococcus sp. (Lecanis fargesii), Phyllococcus brazii (Lecanis spp.) (Lecanis), Pseudococcus brazii (Broccidae), Quadrasidiosus pernicious (Lecanis pelykuporus), Rhalosium spp. (Lecanis viridis), Rhalosium maida (C. zea), Rhalosium paludi (P.) (Lecanis pelykuryi), Phyllopsis bigelovii (Ceratoptera glauca), Phyllosis sp. (Lecanis pelykura), and Thielavia (Black spot), schizaphis graminum (binary Aphis graminum), Sitobion avenae (Piper magnum), Sogatella furcifera (white-backed planthopper), Therioaphis spp (aphids), Toumeyella spp (Lepidoptera), Citrus (Toxoptera spp) (aphids), Trialeurodes spp (whitefly), Trialeurodes vaporariorum (greenhouse whitefly), Trialeurodes abutiloneus (Delphaea zoster), Erysipela (Unaspa spp.) (Lepidula fara), Ungassum yanonensis (Ericaria kuchii), and Zulia entreriana.

In still another embodiment, the insect pest is a Lepidoptera (Lepidoptera), such as Achoea janata, Trichinella (Adoxophyes spp.), Trichinella gossypii (Adoxophyes orana), Trichinella (Agrostis spp.), cutworm (Gekko gecko), Agrotis ipsilon (Gekko japonicas), Arabidopsis argina argillacea (Cotton leafworm), Amorbia cuneana, Amylosis trashitella (navel orange borer), Anacoptidis deflectaria, Anarsia lineolata (peach leaf moth), Antosis sabdaria (Pseudobulbus punctatus), Trichinella punctatus (Bopyriella), Sporidia punctifera (Bopyrifera), Sporidia punctata (Botrys niponica), Sporidia indica (Botrys punctifera), Sporidia indica (Bopyrifera), Sporidia punctifera (Bopyrifera), Sporidia indica (Bopyrifera), Sporina), Sporidia indica (Bopyrina), Sporina (Bombina), Sporina) or Bombina (Bombina), Sporina (Bombina) or Bombina), Bombina (Bombina) or Bombina (Bombina), Bombina) or Bombina (Bombina), Bombina (Bombina), Bombina) or Bombina (Bombina), Bombina) or (Bombina) or Bombina), Bombina (Bombina) or Bombina (Bombina), Bombina (Bombina) or Bombina (Bombina), Bombina (Bombina) or Bombina), Bombina (Bombina) or Bombina (Bombina), Bombina (Bombina), Bombina (Bombina) or Bombina), Bombina (Bombina) or Bombina (Bombina) or Bombina (Bombina), Bombina (Bombina), Bombina (Bombina) or, Choumeta transversa (Spodoptera punctata), Choristoneura rosacea (Trichosporosa rosea), Trichosanthes hordei (Chrysodeixis spp.), Cnaphalous medinalis (Cnaphalocrocis medinalis), Glycine max (Colias spp.), Conpomorpha cramerina, Cossus cosphaea (Epimedium xylophilus), Crambus spp. (meadow moth), Cydia funebrana (Prunus sporeanum), Cydia molesta (Graphomophaga parvum), Cydia niponicas (Cydia niponicas), Cydia nigerina (Pidia pomonella), Cydia pomonella (Aphana pomonella), Sporophora punctata (Pidia pomonella), Sporophora punctata (Dianus), Diaphyta (Dianthus punctiferalis), Sporidia pomifera (Dianthus), Sporidia pomifera punctifera (Spodoptera), Sporidia pomifera punctifera, Sporina (Eisenia punctifera), Sporina (Sporina), Sporina punctifera (Piper punctifera indica (Piper), Sporina punctiferalis (Piper punctiferalis), Sporina punctiferalis (Piper punctifera indica (Piper punctiferalis), Sporina (Piper lineas (Piper punctiferalis), Sporina indica (Piper lineata (Piper punctiferalis), Sporina (Piper punctiferalis), Sporina (Piper lineas (Piper sacchari (Piper lineas) and Sporina), Sporina (Piper sacchari) and Sporina), Sphaealis), Sporina) and Sporina) of Sporina (Piper sacchari) of Sphaepress), Piper sacchari (Piper sacchari) of Sphaepress), Sporina), Sphaepress (Piper sacchari) of Sporina), Piper sacchari (Piper sacchari) of Sporina), Sporina) of Sporina), Sporina (Piper sacchari) of Piper sacchari (Piper sacchari) of Piper sacchari (Piper sacchari) of Piper sacchari (Piper sacchari) of Piper sacchari), Piper sacchari) of Pi, Ephemita cautyla (cabbage moth), Ephemita elutella (tobacco stem borer), Ephemita kuehmeria kuhn (mediterranean pink borer), Epimeces spp, Epinotia aporema, Erionta thrax (banana butterfly), Eupoecilia ambiguella (grape leaf roller), Euxoa auxiliaris (protorhizomes), Feltia spp (root cutting worm), Gortyna spp (graciliate stem worm), Pholita molesta (fruit borer), Hedylepta indica (soybean leaf roller), Helicoverpa spp Lyonetia clavuligera (leaf miner) and Malassena corbeti (leaf knot worm), Trichosporon sp. flavus, Trichosporon fulvescens (yellow brown Meniere caterpillar), Malestra brassiccus (cabbage looper), Maruca testularis (pod borer), Metasa planna (gray moth), Mythimna unipunctata (truer armyma), Neocallinodoides elegans (small tomato burger), Nymphula deputylis (rice stem borer), Operphthora bryuta (winter foot worm), Ostrinia nubilalis (corn borer), Oxydia vesullia, Ostrinia carinatura (cabbage caterpillar), Sphacea virescens (cabbage caterpillar), Spodoptera virescens, Spodoptera (cabbage caterpillar, Spodoptera), Spodoptera virescens (cabbage caterpillar, Spodoptera virescens, Spodoptera melanospodoptera (Spodoptera, Spodoptera melanospodoptera, Sphacea virescens (Sphacea virescens, Sphacea virescens (Sphacea virescens, Sphacea virens (Sphacea) and Sphacea virescens, Sphacea virens (Sphacea) and Sphacea, Sphacea virens (Sphacea) and Sphacea, Sphacea virens (Sphacea) and Sphacea) including Sphacea virens (Sphacea ) including Sphacea, Sphacea virens (Sphacea, Sphacea virens (Sphacea, Sphacea virens (Sphacea virginea) and Sphacea virens (Sphacea) and Sphacea, Sphacea viride, Sphacea viride, Sphacea, Sphac, Plodia interpunctella (Plutella xylostella), Plutella xylostella (Plutella xylostella), polychrosia viteana (Botrytis viticola), Prays endocarpa, Prays oleae (Oleifera armyworm), Pseudobulbus spp. (Spodoptera exigua), Pseudobulbus unicutata (armyworm), Pseudobulbus includens (Spodoptera glycines), Rachiplusia nu, Tryporyza incertulas (Sciophaga incertulas), Heliothis virescens (Sesamia spp.) (borer), Sesamia infrens (Sesamia oryza incertulas), Sesamia nonagrioides, Setora nitens, Sitotrocceella (wheat moth), grape leaf rollers (Spargothria pilifera), Trichoplusia (Spodoptera spp.) (armyworm), Spodoptera exigua (Spodoptera exigua), Spodoptera fugiperda (fall armyworm), Spodoptera littoralis (cotton leaf worm), Spodoptera oridania (southern armyworm), Synanthon spp. (root borer), Therlla basiides, Thermisia gemmatatallis, Tineola bissella (bagewia armyworm), Trichopsis ni (Trichoplusia ni), tomato wheat moth (Tuta absoluta), Nepholitha spp (Yponeuta spp.), coffee wood moth (Zeura coffea) (red leafworm) (red moth), and Zeuzera (panthus pyrifera).

In yet another embodiment, the insect pest is Orthoptera (Orthoptera), such as anaborus simplex (longhorn grasshopper), mole cricket family (gryllotalpidate), Locusta migratoria (Locusta), black Locusta (Melanoplus spp.) (grasshopper), Microcentrum rettinerve (horned wing paletto), pterophhyla spp. (grasshopper species), chimotca gregaria, Scudderia furcata (branchlet ), and vaniicogrorno.

In a further embodiment, the insect pest is from the order of the Thysanoptera (Thysanoptera), such as Frankliniella fusca (tobacco flower Thrips), Frankliniella occidentalis (Frankliniella occidentalis), Frankliniella shalltzii, Frankliniella williamsi (maize Thrips), Heliothrips haemeralis (greenhouse Thrips), Riphithothrips cruentatus, Scirothrix (Sciroththrips spp.), Sciroththrips citri, Scirothrix rhamnoides (Cirsium aurantii), Scirthrips dorsis (Frankliniella tabularis), Taeniothrix rhapontianalis, and Thrips spp.

The mite may be, for example, red spider: (Tetranychus urticae) Apple red spider (A)Panonychus ulmi) Citrus red spider (A)Panonychus citri) Rust mite (I), (II)Aceria anthocoptes) Short-beard mite of orange: (A)Brevipalpus lewisi) Fine mite of Acarus gracilis (1)Brevipalpus phoenicis) Yellow mite (c)Lorryia formosa) And lichen mites (a)Bryobia rubrioculus) Peach silver mite (A), peach silver mite (A)Aculus cornutus) Tetranychus urticae Koch(Tetranychus urticae Koch)。

The mollusk may be, for example, a garden slug(Deroceras reticulatum) Spain and slug(Arion vulgaris) (ii) yellow slug (Limax flavus)、Slug of trees (Limax marginatus) Spain invisible slug(Arion Flagellus) Common yard slugs (Arion distinctus)、Common Keeled slug(Tandonia budapestensis) Big red slug and black slug(Arion ater) Big ash slug(Limax maximus) Grape dental slug(Arion lusitanicus)。

The amount of insecticidal composition of spinetoram and the compound of group a applied is influenced by many environmental factors. The desired effect can be determined under actual use conditions.

The compositions may be applied in various mixtures or combinations of spinetoram and group a compounds, for example in a single "ready to use" form or in a combined spray mixture consisting of separate formulations of a single active ingredient, such as a "tank-mix" form.

In certain embodiments, the composition is administered in the form of a ready-to-use formulation comprising spinetoram and a group a compound. Such formulations may be obtained by combining the mixtures described in the present disclosure with agriculturally acceptable carriers, surfactants, or other application-promoting adjuvants conventionally used in formulation techniques.

The composition comprising (a) spinetoram and (b) a compound of group a may be used in any conventional form, for example in the form of a double pack (twin pack). The compositions may be in the form of, for example, emulsion concentrates ("ECs"), suspension concentrates ("SCs"), soluble concentrates ("SLs"), suspoemulsions ("SEs"), oil dispersions ("ODs"), water dispersible granules ("WDG" or "WGs"), water soluble granules ("SG") and wettable powders ("WPs"). Such compositions may be formulated using agriculturally acceptable carriers, surfactants or other application-promoting adjuvants conventionally used in formulation techniques and formulation techniques known in the art.

In one embodiment, the amount of active ingredient in the composition is from 0.01 to 99.9 weight percent ("wt.%), particularly from 0.1 to 99 weight percent, more particularly from 0.1 to 95 weight percent, and even more particularly from 0.1 to 90 weight percent, based on the total weight of the composition.

Examples of suitable solid carriers include mineral earths, such as silica gel, silicates, talc, kaolin, activated clays (attacalay), limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium oxide, sodium carbonate and sodium bicarbonate and sulfate, ground synthetic materials, fertilizers, such as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea, and products of vegetable origin, such as cereal flour, bark flour, wood flour and nutshell flour, cellulose flour and other solid carriers.

Examples of suitable liquid carriers include water, alcohols such as methanol, cyclohexanol and decanol, ethylene and polypropylene glycols, N-dimethylformamide, dimethyl sulfoxide, N-alkylpyrrolidones, aromatic hydrocarbons such as alkylbenzenes and alkylnaphthalenes, paraffin, olive oil, castor oil, linseed oil, tung oil, sesame oil, corn oil, peanut oil, cottonseed oil, soybean oil, rapeseed oil and coconut oil, fatty acid esters, ketones such as cyclohexanone, 2-heptanone, isophorone and 4-hydroxy-4-methyl-2-pentanone, and the like.

The term "surfactant" as used herein refers to an agriculturally acceptable material that provides emulsifiability, stability, dispersion, wetting, dispersibility, or other surface modification properties. Examples of suitable surfactants include nonionic, anionic, cationic and amphoteric types of surfactants such as lignosulfonates, fatty acid sulfonates (e.g., dodecyl sulfonate), phosphate esters such as phosphate esters of alcohol alkoxylates, phosphate esters of alkylphenol alkoxylates and phosphate esters of styrylphenol ethoxylates, condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, condensates of naphthalene or naphthalene sulfonic acids with phenol and formaldehyde, alkylaryl sulfonates, ethoxylated alkylphenols and arylphenols, polyalkylene glycols and ethoxylated fatty alcohols.

Other ingredients, such as wetting agents, adhesives, thickeners, binders, fertilizers or antifreeze agents, can also be added to the composition including the combination of spinetoram and the group a compound to increase the stability, density and viscosity of the composition.

In one embodiment, the combined amount of spinetoram and the group a compound, taken together, in the ready-to-use formulation (composition) is from 0.1 to 99% by weight.

In one embodiment, the combined amount of spinetoram and the group a compound, taken together, in the ready-to-use formulation is from 0.1 to 95% by weight.

In another embodiment, the amount of spinetoram and group A compounds in total in a ready-to-use formulation (composition) is 10^-499% by weight, 10^-399% by weight or 10^-2-99% by weight. In a specific embodiment, the amount of spinetoram and group A compounds together in a ready-to-use formulation (composition) is 10^-510% by weight of^-5-1% by weight, 10^-5-0.1% by weight, 10^-410% by weight of^-4-5% by weight, 10^-42% by weight, 10^-4-1% by weight, 10^-4 –0.5% by weight or 10^-4-0.1 wt%.

The remaining components in the formulation are, for example, carriers and additives. In particular embodiments, the carrier is aqueous-based.

According to another aspect, a kit is provided comprising (a) at least one container comprising spinetoram; (b) at least one container comprising a compound of group a selected from novaluron, pyriproxyfen, tau-fluvalinate, and combinations thereof; and (c) instructions for applying said spinetoram and said group A compound to a pest or to a locus where control of a pest is desired.

In one embodiment, spinetoram and the group a compound are administered concomitantly or sequentially.

According to yet another aspect, a kit is provided comprising (a) at least one container comprising (i) spinetoram; and (ii) a compound of group a selected from novaluron, pyriproxyfen, cyfluthrin, and combinations thereof; and (b) instructions for applying said spinetoram and said group A compound to a pest or to a locus where control of a pest is desired.

The instructions may be in the form of printed matter, such as an insert or label.

As long as the effect of the combination of active ingredients is greater than the sum of the individual effects of the ingredients, there is a synergistic effect. Thus, a synergistically effective amount (or an effective amount of a synergistic composition or combination) is an amount that exhibits greater insecticidal activity than the sum of the insecticidal activities of the components.

In the field of agriculture, it is generally understood that the term "synergistic effect" is defined as in an article entitled "stabilizing synthetic and antibacterial responses of biological compositions" as disclosed in Colby s. r. in journal Weeds, 1967, 15, pages 20-22, which is incorporated herein by reference in its entirety. The expected effect of a given combination of two active ingredients can be calculated as follows:

where E represents the expected percent insecticidal control of the combination of the two pesticides at the stated dose (e.g., equal to X and Y, respectively), X is the percent insecticidal control observed for spinetoram at the stated dose (equal to X), and Y is the percent insecticidal control observed for the compound of group a at the stated dose (equal to Y). When the percentage of insecticidal control observed for the combination is greater than the expected percentage, there is a synergistic effect.

It is to be appreciated that the spinetoram and group a compounds described in one particular aspect of the invention may be characterized by the various features described in other aspects of the invention, such as weight ratios, amounts applied, and the like.

It will be appreciated that one or more features, aspects or embodiments of the invention may be combined with one or more other features, aspects or embodiments of the invention.

It will be appreciated that all embodiments of the invention, including those specifically described for different aspects of the invention, may be combined with any other embodiment of the invention as appropriate.

Detailed description of the preferred embodiments

Examples

Brassica oleracea L var. Example 1 Diphenylflubenzuron and spinetoram control of cabbage (C.), (B.), (C.), (C. capitata Brassica oleracea L var. italica) And Plutella xylostella (Plutella) on Cauliflower () xylostella)

Two trials were performed in the La Plata zone (Buenos Aires, Argentina) -one trial for cabbage crops and one trial for cauliflower crops, with the aim of assessing the efficacy and interaction of bisfenoxuron and spinetoram in the control of plutella xylostella. For the preparation of the mixture, spinetoram (Delegate) was used^®250g of a.i./Kg WG, Dow Agrosciences LLC) and novaluron (Rimon)^®Supra 100g a.i// Liter SC, Makhtesim Agan Group Company). For each of the treatments in examples 1-6, a measured amount of the formulated product was diluted with water to obtain a mixture.

With bars 2.1 m wide with spray heads set 0.525 m apart from each other and 8002 flat fansA knapsack sprayer with a nozzle. In all cases, from 5 p.m. to 7 p.m. at 150 l.ha^-1Application is carried out at an application rate of (l/ha).

Plots 10 meters long were used, each divided into four ridges. Only three ridges were applied. A ridge wide buffer is left between plots to minimize drift. The experimental design included randomized blocks that were replicated four times.

The evaluations at 1, 3 and 7 days after application are listed in table B below. The number of larvae per plant (LP) is the average of 10 plants per plot. Average 4 replicates. The% control efficacy in examples 1-6 was calculated based on the untreated control evaluated on the same day.

Table a. description of each experiment.

Table B results

Test 1-cauliflower

(. in this table and the following tables, the term "ai" refers to the active ingredient.

Test 2-cabbage

Zea mays var. saccharataExample 2-Pseudomyxozoa in sweet corn () (Spodox frugiperda)Moth (Spodoptera frugiperda)) in controlling diflubenzuron and spinetoram

Two trials were conducted on sweet corn crops in the Or n region (Salta, Argentina) with the objective of evaluating the foliar application of novaluron and spinetoram against Pseudomyxobolus (R) ((R))Spodoptera frugiperda) Potency and interaction. For the preparation of this mixture, the product used is as described in example 1.

Application was carried out with a knapsack sprayer equipped with a 2.1 m wide bar with spray heads set at 0.525 m from each other and equipped with 8002 flat fan nozzles. In all cases, between 6 p.m. and 9 p.m. at 205 l.ha^-1Is administered at the amount administered.

Plots 10 meters long were used, each divided into four ridges. Only three ridges were applied. A ridge wide buffer is left between plots to minimize drift. The experimental design included randomized blocks that were replicated four times.

The evaluations at 1, 3 and 7 days after application are listed in table B below. The number of larvae per plant (LP) was the average of 10 plants per plot (average of 4 replicates). The% efficacy was calculated in the same manner as described in example 1.

TABLE A description of the experiments

Table B results

Test 1

% effectiveness (based on number of larvae/plant)

Test 2

% effectiveness (based on number of larvae/plant)

Capsicum annuum Trialeurodes Example 3 whiteflies (greenhouse whiteflies: (green house whiteflies) in pepper () vaporariorum) Pyriproxyfen and spinetoram for preventing and treating pyriproxyfen and spinetoram

The efficacy of pyriproxyfen and spinetoram on whitefly control in pepper crops was evaluated.

Two trials were carried out on pepper crops in vegetable-planted strips of La Plata (science of Buenos Aires, Argentina) with the aim of assessing the efficacy and interaction of pyriproxyfen and spinetoram against whiteflies. For the preparation of this mixture, the spinetoram product used was the same as in example 1, pyriproxyfen (epigle) was used^® 100g a.i./L EC, Sumitomo Chemical Co., Ltd.)。

Application was carried out using a knapsack sprayer equipped with a vertical rod and a constant pressure regulator, with spray heads set at a distance of 0.30 meters from each other and with 8002 flat fan nozzles. In all cases, 900-^-1(L/ha) is applied at an application rate. Plots 8 meters long were used, each divided into four ridges (8 rows of plants). The application is carried out on two ridges, while the other two ridges are left as buffers. The experimental design included randomized blocks that were replicated four times.

The number of whitefly adults per leaf is evaluated, for example, at 1, 3, 5, 7, 10 and 14 days after application, and the number of whitefly nymphs per leaf is evaluated, for example, at 10, 14, 21 and 29 days after application. For this evaluation, 10 leaves were taken from plants located in the middle row of each plot, taking care to avoid the first and last meters of each plot. Control efficacy (%) was calculated based on untreated controls.

Description of the respective tests

Test 2

(a) Spinetoram; (b) pyriproxyfen.

Capsicum annuum Frankliniella Example 4-treatment of Frankliniella occidentalis in Pepper () ( occidentalis) Pyriproxyfen and spinetoram

This study was conducted to evaluate the efficacy of and interaction between pyriproxyfen and spinetoram on frankliniella occidentalis in pepper crops.

Two trials were carried out on pepper crops in vegetable-growing strips of La Plata (science of Buenos Aires, Argentina) with the aim of assessing the efficacy and interaction of pyriproxyfen and spinetoram on thrips occidentalis. For the preparation of this mixture, the product used was the same as in example 3.

Application was carried out using a knapsack sprayer equipped with a vertical rod and a constant pressure regulator, with spray heads set at a distance of 0.30 meters from each other and with 8002 flat fan nozzles. In all cases, 790 and 937 l.ha^-1Is administered at the amount administered. Using 8 m long plots, each divided into fourRidges (8 rows of plants). The application is carried out on two ridges, while the other two ridges are left as buffers. The experimental design included randomized blocks that were replicated four times.

The number of thrips (all stages) per flower is evaluated, for example, 1, 3, 5, 7, 10 and 14 days after administration. For this evaluation, 10 flowers were taken from plants located in the middle row of each plot, taking care to avoid the first and last meters of each plot. Control efficacy (%) was calculated based on untreated controls.

Detailed description of each experiment:

test 1

Test 2

Capsicum annuum Trialeurodes Example 5-treatment of whitefly (greenhouse whitefly: (green house whitefly) (ii) capsicum () in capsicum annuum L.) vaporariorum) Cyhalothrin and spinetoram

Two trials were conducted on pepper crops in vegetable-planted strips of La Plata (science of Buenos Aires, Argentina) with the aim of assessing the efficacy and interaction of foliar cyfluthrin and spinetoram on whitefly control. For the preparation of this mixture, the spinetoram product used was the same as in example 1, fluvalinate (Mavrik) was used^® 240g a.i./L EW, Makhteshim Agan Group Company)。

Application was carried out using a knapsack sprayer equipped with a vertical rod and a constant pressure regulator, with spray heads set at a distance of 0.30 meters from each other and with 8002 flat fan nozzles. In all cases, at 810-^-1Is administered at the amount administered. Plots 8 meters long were used, each divided into four ridges (8 rows of plants). The application is carried out on two ridges, while the other two ridges are left as buffers. The experimental design included randomized blocks that were replicated four times.

The number of whitefly adults per leaf is evaluated, for example, at 1, 3, 5, 7, 10 and 14 days after application, and the number of whitefly nymphs per leaf is evaluated, for example, at 11, 15 and 21 days after application. For this evaluation, 10 leaves were taken from plants located in the middle row of each plot, taking care to avoid the first and last meters of each plot. Control efficacy (%) was calculated based on untreated controls.

TABLE A detailed description of the experiments

Example 6-treatment of Frankliniella occidentalis (Frankliniella) in Capsicum annuum (Capsicum annuum) occidentalis) Cyfluthrin and Spinetoram

This study was conducted to evaluate the efficacy of fluvalinate and spinetoram on and the interaction between frankliniella occidentalis in pepper crops.

Two trials were carried out on pepper crops in vegetable-planted strips of La Plata (science of Buenos Aires, Argentina) with the aim of assessing the efficacy and interaction of fluvalinate and spinetoram on frankliniella occidentalis.

Application was carried out using a knapsack sprayer equipped with a vertical rod and a constant pressure regulator, with spray heads set at a distance of 0.30 meters from each other and with 8002 flat fan nozzles. In all cases, 790 and 937 l.ha^-1Is administered at the amount administered. Plots 8 meters long were used, each divided into four ridges (8 rows of plants). The application is carried out on two ridges, while the other two ridges are left as buffers. The experimental design included randomized blocks that were replicated four times.

The number of thrips (all stages) per flower is evaluated, for example, 1, 3, 5, 7, 10 and 14 days after administration. For this evaluation, 10 flowers were taken from plants located in the middle row of each plot, taking care to avoid the first and last meters of each plot. Control efficacy (%) was calculated based on untreated controls.

Description of the respective tests

Test 1

Test 2

Phytotoxicity

No signs were observed in any of the treatments of examples 1-6.

Conclusion

The results showed excellent control efficacy of the combination of spinetoram and the co-components (novaluron, pyriproxyfen, cyfluthrin) against pests. In addition, these combinations provide excellent control of more than one pest that tend to be present on a plant at the same time.

While the invention has been shown and described with reference to the preferred embodiments thereof, it will be understood by those skilled in the art that many substitutions, modifications and changes may be made thereto without departing from the spirit and scope of the invention. Accordingly, it is intended to embrace all such alternatives, modifications and variations that fall within the spirit and broad scope of the appended claims.

All publications, patents, and patent applications mentioned in this specification are herein incorporated in their entirety by reference into the specification, to the same extent as if each individual publication, patent, or patent application was specifically and individually indicated to be incorporated herein by reference.