阅读说明：本技术 一种可减少干扰的便携式尿检试纸 (A kind of portable urine test paper reducing interference ) 是由 黄连生 陈静 于 2019-08-27 设计创作，主要内容包括：本发明公开一种可减少干扰的便携式尿检试纸,包括：基片、所述基片上的试纸块和所述试纸块间的隔离垫,所述基片上的试纸块按从基片一端到另一端的排列顺序依次包括：抗坏血酸试纸块、pH试纸块、比重试纸块、蛋白质试纸块、葡萄糖试纸块、钙离子试纸块、隐血试纸块、尿胆原试纸块、胆红素试纸块、酮体试纸块、肌酐试纸块、白细胞试纸块、微量白蛋白试纸块、亚硝酸盐试纸块、补偿垫。本发明通过优化试纸条排序,在试纸块间设计隔离垫,减少相互干扰；通过在试纸块的绒制层添加碘酸钾、氯酸钠试剂减少抗坏血酸的干扰,并相应增加了一块检测抗坏血酸的试剂块作为对照检验结果的准确性,最大程度的减少抗坏血酸的影响。(The present invention discloses a kind of portable urine test paper that can reduce interference, it include: substrate, the isolating pad between indicator paper block and the indicator paper block on the substrate, indicator paper block on the substrate successively includes: ascorbic acid indicator paper block by putting in order from substrate one end to the other end, pH indicator paper block, specific gravity indicator paper block, protein indicator paper block, Glucose strips block, calcium ion indicator paper block, it occults blood indicator paper block, urobilinogen indicator paper block, bilirubin indicator paper block, ketoboidies indicator paper block, creatinine indicator paper block, leucocyte indicator paper block, microalbumin indicator paper block, nitrite indicator paper block, compensation pad.The present invention designs isolating pad, reduction interferes with each other by optimization test strips sequence between indicator paper block；The interference of Potassiumiodate, chloric acid sodium reagent reduction ascorbic acid is added by the suede preparative layer in indicator paper block, and has increase accordingly accuracy of the reagent block of one block of detection ascorbic acid as control test result, reduces the influence of ascorbic acid to the greatest extent.)

1. the portable urine test paper that one kind can reduce interference characterized by comprising the indicator paper block on substrate, the substrate Isolating pad between the indicator paper block, the indicator paper block on the substrate are successively wrapped by putting in order from substrate one end to the other end Include: ascorbic acid indicator paper block, pH indicator paper block, specific gravity indicator paper block, protein indicator paper block, Glucose strips block, calcium ion indicator paper block, It occults blood indicator paper block, urobilinogen indicator paper block, bilirubin indicator paper block, ketoboidies indicator paper block, creatinine indicator paper block, leucocyte indicator paper block, micro Albumin indicator paper block, nitrite indicator paper block, compensation pad.

2. the portable urine test paper according to claim 1 for reducing interference, which is characterized in that the material of the isolating pad Material is hydrophobic material.

3. the portable urine test paper according to claim 1 for reducing interference, which is characterized in that the height of the isolating pad Degree is greater than the thickness of indicator paper block.

4. the portable urine test paper according to claim 1 for reducing interference, which is characterized in that the indicator paper block is pressed certainly Sequence on down includes four-layer structure: support layer, water absorption layer, suede preparative layer and nylon mesh layer.

5. the portable urine test paper according to claim 4 for reducing interference, which is characterized in that the indicator paper block of occulting blood Water absorption layer be two layers.

6. the portable urine test paper according to claim 4 for reducing interference, which is characterized in that the suede preparative layer includes Anti-interference layer and reagent layer.

7. the portable urine test paper according to claim 6 for reducing interference, which is characterized in that Glucose strips block and Occult blood indicator paper block anti-interference layer be Potassiumiodate layer.

8. the portable urine test paper according to claim 6 for reducing interference, which is characterized in that leucocyte indicator paper block, The anti-interference layer of bilirubin indicator paper block, nitrite indicator paper block and urobilinogen indicator paper block is sodium chlorate layer.

9. the portable urine test paper according to claim 1 for reducing interference, which is characterized in that the urine test paper covers It is stamped SF packing film.

Technical field

The present invention relates to urine examination technical fields, more particularly to a kind of portable urine test paper that can reduce interference.

Background technique

Routine urianlysis is clinically the inspection that can not ignore, and diabetes, hypertension, chronic kidney disease etc. are chronic Disease incidence increases year by year, and regularly routine urinalysis detection can supervise this respect the severity of disease and progress It surveys.It is microscopic examination of urine sediment method and routine urinalysis dry chemical method respectively now there are mainly two types of urine detection methods.With urine correlation The development of detection technique, routine urinalysis Dry chemical method are widely used in clinic.Routine urinalysis dry chemical method mainly uses Test paper and pertinent instruments quickly examine the ingredient of urine, rapidly can carry out multinomial qualitative or sxemiquantitative to urine.Urine Liquid Dry chemical method has the characteristics that sample dosage is few, detection speed is fast, detection project is more, accuracy is good, easy to operate.

With popularizing for urine detection, there is millions of people to need to carry out urine detection daily, but currently, this is routinely examined Looking into can only complete in hospital.However for the patients such as pregnant woman, nephrosis, urine examination is the inspection item of a routine, inspection Frequency is very high, repeatedly dealing hospital, to handicapped artificial at many puzzlements.Therefore the urine detection being suitable for home use Test strips are the new directions of routine urinalysis detection development.

The reaction principle of urine test paper item is to be carried out using the reagent block on urine test paper item to corresponding ingredient each in urine React and generate color change, the depth of reaction color and corresponding detection component content proportion relation, indicator paper block face Color and colorimetric card comparison are to make preliminary judgement to the development of disease.

Existing urinalysis test paper stability is poor, and each detection project interferes with each other each other, also suffers from The influence of other chemical substances, testing result are not accurate enough in urine.The height of ascorbic acid (VC) content is to urine point in urine Analysis detection hemoglobin, bilirubin, glucose etc. cause different degrees of interference.Cause the detection knot of false negative or weakly positive Fruit leads to the diagnosis of mistake.A kind of method that patent CN204116237U describes 14 urine test paper items for reducing interference, Its interference optimizing sequence to indicator paper block according to the characteristic of each reagent block to reduce each indicator paper block, however this mode The interference of ascorbic acid can not be reduced to the greatest extent, though provided with ascorbic acid reagent block in patent CN106645676A Detection, thus judge influence of the ascorbic acid to urine specimen, the confidence level of indirect judgment experiment result.But this mode Though harm is exactly that can judge the influence of ascorbic acid, inevitably to be detected again.It is same to waste test strips When delay making a definite diagnosis for the state of an illness.

The enzyme as contained in the test paper pad of detection project each in test strips, as glucose oxidase, peroxidase and The reaction phase of other compositions, is blended on test paper pad, it is likely that occur one because of moisture absorption in various chemical substances contained by form and aspect Sequence of chemical reacts and test paper is caused to fail.Therefore, during preservation it is noted that be sealed, avoid test paper is rotten from losing Effect, brings the deviation of testing result.Described in patent CN105158452A it is a kind of can to the inspection health stick that test strips are sealed, It includes urine detection test paper, detecting pad, detector bar and rodlike pipe.Though the leakproofness of Test paper can be reinforced, each examination Paper is equipped with a vacuum transparent pipe and increases cost, and urine test paper is easy consumption for the patient that need to be periodically detected Product pack the financial burden of excessively meeting making patients.Meanwhile discarded rodlike pipe also can cause environmental pollution.

Carrying out routine urianlysis using test paper is a kind of simple and direct quick method of inspection.Ten, 11 test paper source areas In Germany, it is sold to that China is expensive, and many hospitals are reluctant to receive；The routine urinalysis inspection that various big hospital is carried out at present is generally adopted With ten, 11, ten binomial test paper, and 13, the indexs such as creatinine in 14 test paper have to urine screening it is important Effect.

So a kind of structure is simple, strong interference immunity is cheap, easy to use, the family containing multinomial detection project Urine test paper possesses wide market.

Therefore, the existing technology needs to be improved and developed.

Summary of the invention

In view of above-mentioned deficiencies of the prior art, the purpose of the present invention is to provide the portable urine examinations that one kind can reduce interference Test paper, it is intended to solve the problems, such as that existing test paper will receive the influence of ascorbic acid and lead to result error.

Technical scheme is as follows:

A kind of portable urine test paper reducing interference, wherein include: substrate, the indicator paper block on the substrate and institute The isolating pad between indicator paper block is stated, the indicator paper block on the substrate successively includes: by putting in order from substrate one end to the other end It is ascorbic acid indicator paper block, pH indicator paper block, specific gravity indicator paper block, protein indicator paper block, Glucose strips block, calcium ion indicator paper block, hidden It is blood indicator paper block, urobilinogen indicator paper block, bilirubin indicator paper block, ketoboidies indicator paper block, creatinine indicator paper block, leucocyte indicator paper block, micro white Albumen indicator paper block, nitrite indicator paper block, compensation pad.

Further, the material of the isolating pad is hydrophobic material.

Further, the height of the isolating pad is greater than the thickness of indicator paper block.

Further, the indicator paper block includes four-layer structure by sequence from bottom to top: support layer, water absorption layer, suede preparative layer And nylon mesh layer.

Further, the water absorption layer of the indicator paper block of occulting blood is two layers.

Further, the suede preparative layer includes anti-interference layer and reagent layer.

Further, the anti-interference layer of Glucose strips block and indicator paper block of occulting blood is Potassiumiodate layer.

Further, leucocyte indicator paper block, bilirubin indicator paper block, nitrite indicator paper block and urobilinogen indicator paper block is anti-dry Disturbing layer is sodium chlorate layer.

Further, the urine test paper is covered with SF packing film.

The utility model has the advantages that the present invention designs isolating pad, it is possible to reduce indicator paper block by optimization test strips sequence between indicator paper block Between interfere with each other.

Detailed description of the invention

Fig. 1 is the positive structure schematic for the portable urine test paper that one kind of the invention can reduce interference；

Fig. 2 is the side structure schematic diagram of portable urine test paper and putting for the portion A that one kind of the invention can reduce interference Big figure；

Fig. 3 is the decomposition texture schematic diagram for the portable urine test paper that one kind of the invention can reduce interference.

Specific embodiment

The present invention provides a kind of portable urine test paper that can reduce interference, for make the purpose of the present invention, technical solution and Effect is clearer, clear, and the present invention is described in more detail below.It should be appreciated that specific embodiment described herein It is only used to explain the present invention, be not intended to limit the present invention.

The embodiment of the present invention provides a kind of portable urine test paper that can reduce interference, wherein as shown in Figure 1, comprising: base Piece 1, the indicator paper block on the substrate 1 and the isolating pad between the indicator paper block, the indicator paper block on the substrate are pressed from substrate one end It successively include: ascorbic acid indicator paper block 2, pH indicator paper block 3, specific gravity indicator paper block 4, protein indicator paper block to putting in order for the other end 5, Glucose strips block 6, calcium ion indicator paper block 7, indicator paper block 8 of occulting blood, urobilinogen indicator paper block 9, bilirubin indicator paper block 10, ketoboidies examination Paper block 11, creatinine indicator paper block 12, leucocyte indicator paper block 13, microalbumin indicator paper block 14, nitrite indicator paper block 15, compensation pad 16.Isolating pad 17 is provided between the indicator paper block.The present invention designs isolating pad by optimization test strips sequence between indicator paper block, Reduce interfering with each other between indicator paper block and indicator paper block.

In one embodiment, the material of the isolating pad is hydrophobic material.

In one embodiment, it as shown in Fig. 2, the height of the isolating pad is greater than the thickness of indicator paper block, plays more preferable Insulation blocking effect.

In one embodiment, as shown in figure 3, the indicator paper block by sequence from bottom to top includes four-layer structure:

First layer is support layer B, is mainly made by the nonwettable material of urine such as plastic sheet, and what is played is the work supported With.Wherein plastic sheet includes holding area and detection zone, and detection zone includes the isolating pad between indicator paper block and indicator paper block for detection. The sequence of the indicator paper block detection project from the detection zone beginning to connect with holding area to detection zone end successively are as follows: ascorbic acid Indicator paper block, pH indicator paper block, specific gravity indicator paper block, protein indicator paper block, Glucose strips block, calcium ion indicator paper block, indicator paper block of occulting blood, Urobilinogen indicator paper block, bilirubin indicator paper block, ketoboidies indicator paper block, creatinine indicator paper block, leucocyte indicator paper block, microalbumin test paper Block, nitrite indicator paper block, compensation pad；

The second layer is water absorption layer C, is mainly made of blotting paper, and effect is urine can be made uniformly and quickly to penetrate into and energy Urine is inhibited to flow to adjacent reaction area.Wherein occult blood indicator paper block 8 water absorption layer be two layers；

Third layer is suede preparative layer D, and suede preparative layer has anti-interference layer and reagent layer again, wherein Glucose strips block 6 and examination of occulting blood The anti-interference layer of paper block 8 is Potassiumiodate layer, and is located at the outermost layer of suede preparative layer；Leucocyte indicator paper block 13, bilirubin indicator paper block 10, The anti-interference layer of nitrite indicator paper block 15 and urobilinogen indicator paper block 9 is sodium chlorate layer, and is located at the outermost layer of suede preparative layer；Wherein In the suede preparative layer of leucocyte indicator paper block 13, diazonium salt deposit and reagent layer are split up into two layers.The effect of the anti-interference layer is to destroy The interfering substances such as ascorbic acid, reagent layer contain agent formulations, mainly react with chemical substance detected in urine；

4th layer is nylon mesh layer E, and nylon wire plays fixed protection, and can prevent macromolecular complex from verifying and react Pollution.

Due to red blood cell indicator paper block, Glucose strips block, leucocyte indicator paper block, bilirubin indicator paper block, the urine gallbladder in urine examination Former indicator paper block, ketoboidies indicator paper block and nitrite indicator paper block can all be influenced by ascorbic acid and lead to result error.This hair One kind of bright offer, which can be reduced in its detection reagent block of the portable urine test paper of interference, makes following adjustment to reduce interference:

1. Potassiumiodate is added in Glucose strips block and indicator paper block of occulting blood.

2. chloric acid is added in leucocyte indicator paper block, bilirubin indicator paper block, urobilinogen indicator paper block and nitrite indicator paper block Sodium.

3. the amount of sodium hydroxide increases in ketoboidies indicator paper block.

In a preferred embodiment, the urine test paper is covered with SF packing film.Used SF is fit Packaging film has the characteristics that excellent transparency, draftability and puncture are excellent, can effectively completely cut off air and steam, can be effective Extend the storage life of product.

Urine test paper of the present invention is stored in sealing, moisture-proof, is stored at room temperature in the test paper bottle being protected from light.When use from test paper bottle It takes out test paper and rapidly covers test paper bottle cap.The SF packing film covered on test paper is torn, test paper is soaked completely The not about 1s in urine sample to be measured；When taking out diaper, diaper edge is wiped along urine cup edge, to remove extra urine；60s Afterwards, the color that will test plate is compared with the color scale on test paper bottle, and band is face-down when operation, finger far from sample, Keep cleaning and safety.

In conclusion one kind of the invention can reduce the portable urine test paper of interference.The present invention passes through optimization test strips Sequence, designs isolating pad, reduction interferes with each other between indicator paper block；Potassiumiodate, sodium chlorate are added by the suede preparative layer in indicator paper block Reagent reduces the interference of ascorbic acid, and has increase accordingly the reagent block of one block of detection ascorbic acid as control test result Accuracy reduces the influence of ascorbic acid to the greatest extent；By covering one layer of SF packing film that can be torn on test paper, The problems such as completely cutting off air and moisture, solving oxidation easy to moisture absorption in test strips access procedure.

It should be understood that the application of the present invention is not limited to the above for those of ordinary skills can With improvement or transformation based on the above description, all these modifications and variations all should belong to the guarantor of appended claims of the present invention Protect range.