阅读说明：本技术 柑橘属果实挥发油在制备治疗皮脂腺囊肿食品、药品中的应用及其制备的食品、药品 (Food, the drug of application and its preparation of the citrus fruits volatile oil in preparation treatment sebaceous cyst food, drug ) 是由 吴逸群 常瑞欣 杨达 于 2019-06-14 设计创作，主要内容包括：本发明公开了柑橘属果实挥发油在制备调节人体内分泌系统,用于皮脂腺囊肿的食品、药品中的应用,所述的柑橘属果实为甜橙、佛手组合或甜橙、佛手、沙田柚、葡萄柚组合或甜橙、沙田柚、葡萄柚、宽皮桔、佛手组合,柑橘属植物挥发油食品与药品的开发,使柑橘属果实的果皮得到充分利用,避免资源的浪费,此外可以通过口服有效治疗皮脂腺囊肿。(The invention discloses citrus fruits volatile oil to adjust human endocrine system in preparation, for the application in the food of sebaceous cyst, drug, the citrus fruits are sweet orange, fingered citron combination or sweet orange, fingered citron, shatian pomelo, grape fruit combination or sweet orange, shatian pomelo, grape fruit, loose-skin orange, fingered citron combination, the exploitation of citrus plant volatilization oil food and drug, the pericarp of citrus fruits is set to be fully used, the waste of resource is avoided, oral effectively treatment sebaceous cyst furthermore can be passed through.)

1. citrus fruits volatile oil adjusts human endocrine system in preparation, for treating food, the drug of sebaceous cyst In application.

2. the application of citrus fruits volatile oil according to claim 1, it is characterised in that: the citrus fruits are Sweet orange, fingered citron, shatian pomelo, grape fruit, loose-skin orange any or multiple combinations constitute.

3. the application of citrus fruits volatile oil according to claim 1, it is characterised in that: the pericarp of citrus fruits is cut After block, using extraction by steam distillation and volatile oil is collected, subsequent dewatering obtains citrus fruits volatile oil.

4. the application of citrus fruits volatile oil according to claim 1, it is characterised in that: the food, drug use Capsule, tablet or pressed candy or gel candy form.

5. a kind of food prepared by citrus fruits volatile oil, drug, it is characterised in that: including citrus fruits volatile oil.

6. the food according to claim 5 prepared by citrus fruits volatile oil, drug, it is characterised in that: Citrus Fruit volatile oil is contained in citrus fruits volatile oil powdered oil or citrus fruits volatile oil tablet or is wrapped in edible It is outer intradermal.

7. the food according to claim 5 prepared by citrus fruits volatile oil, drug, it is characterised in that: further include Filler, lubricant, preservative, sweetener, disintegrating agent, adhesive, plasticizer, diluent, glidant, colorant, solubilizer, One of dispersing agent, wetting agent, surfactant or multiple combinations.

8. the food according to claim 7 prepared by citrus fruits volatile oil, drug, it is characterised in that: filler Including dextrin, cyclodextrin and starch；Sweetener includes lactose, xylitol and D-sorbite；Lubricant includes magnesium stearate；Anti-corrosion Agent includes sodium benzoate；Disintegrating agent includes hydroxypropyl cellulose；Diluent includes mannitol, microcrystalline cellulose, lactose, corn shallow lake Powder；Wetting agent includes polysorbate；Plasticizer includes repefral, glyceryl diacetate, 1,2- propylene glycol, sweet Oil；Surfactant includes ethyl alcohol, propolis.

9. the food according to claim 5 prepared by citrus fruits volatile oil, drug, it is characterised in that: the medicine Product are by as follows at being grouped as: citrus fruits volatile oil powdered oil 1-40 parts by weight, cyclodextrin 5-30 parts by weight, starch 5-40 Parts by weight, dextrin 5-30 parts by weight, lactose 5-60 parts by weight, xylitol 5-60 parts by weight, D-sorbite 5-60 parts by weight are stearic Sour magnesium 0.1-4 parts by weight, sodium benzoate 0.1-0.2 parts by weight, hydroxypropyl cellulose 2-10 parts by weight.

10. the food according to claim 9 prepared by citrus fruits volatile oil, drug, it is characterised in that: the medicine Product are by as follows at being grouped as: 30 parts by weight of citrus fruits volatile oil powdered oil, 25 parts by weight of cyclodextrin, 20 weight of starch Part, 5 parts by weight of dextrin, 10 parts by weight of lactose, 15 parts by weight of xylitol, 15 parts by weight of D-sorbite, 0.8 weight of magnesium stearate Part, 0.1 parts by weight of sodium benzoate, 5 parts by weight of hydroxypropyl cellulose.

11. the food according to claim 6 prepared by citrus fruits volatile oil, drug, it is characterised in that: Citrus The preparation process of fruit volatile oil powdered oil is as follows: citrus fruits volatile oil, starch octenyl succinate anhydride solution press than After example mixing, high speed shear, homogeneous under high pressure prepares citrus fruits volatile oil powdered oil by the method for spray drying.

12. the food according to claim 11 prepared by citrus fruits volatile oil, drug, it is characterised in that: spraying Drying condition is 190 DEG C of inlet air temperature, and 90-100 DEG C of leaving air temp, sample introduction speed is 30mL/min, and centrifugal atomizer revolving speed is 20000r/min。

13. the food according to claim 11 prepared by citrus fruits volatile oil, drug, it is characterised in that: citrus Belong to fruit volatile oil, starch octenyl succinate anhydride solution is mixed by the mass ratio of 1:4.

Technical field

The present invention relates to a kind of citrus fruits volatile oil preparation treatment sebaceous cyst food, the application in drug and Its food prepared, drug.

Background technique

Sebaceous cyst is commonly called as " sebaceous cyst ", blocks mainly due to sebum gland excretory duct, and sebaceous glands cryptomere epithelium is gradually increased More content expansions are formed by retention cyst, and feature is the benign lesion slowly increased, intracapsular to have white bean dregs sample Secretion.Any age can be betided, but common with person between twenty and fifty, be apt to occur in head, neck and chest and back.Sebaceous cyst is prominent In skin surface, general no conscious sympton, such as secondary infection Shi Keyou pain is suppurated.Sebaceous cyst is to the daily of patient Life brings many inconvenience and slight illness, thus the treatment of sebaceous cyst be very it is necessary to.But skin is treated at present The means of adipose gland tumour are mainly local anaesthesia resection, are taken time and effort.Therefore exploitation being capable of oral medication sebum glandular sac Swollen and product without side-effects has a very important significance.

Currently, citrus plant fingered citron and sweet orange are planted within the scope of China extensively, yield of the fingered citron in Jinhua, Zhejiang Reach 400-500 tons of annual output, is mainly used as fingered citron potted landscape and fresh fruit sale, but industry size constantly expands and city in recent years Field does not expand, therefore results in the unsalable of fingered citron and waste, so exploitation fingered citron is more multi-functional, pushes fingered citron intensive processing Develop particularly important to fingered citron industry；The yield of China's sweet orange has reached 7,000,000 tons at present, and sweet orange in the market mainly as Fruit is edible and prepares orange juice, and pericarp is largely dropped and is underutilized, and causes the great wasting of resources and ring Border pollution, therefore reinforce the intensive processing of sweet orange, sweet orange resource can be made to be fully used, promote the continuous hair of sweet orange industry Exhibition.

Summary of the invention

It is an object of the invention to overcome the above deficiencies in the existing technologies, and provide a kind of citrus fruits volatilization Food, the drug of application and its preparation of the oil in preparation treatment sebaceous cyst food, drug.

Technical solution used by the present invention solves the above problems is:

Citrus fruits volatile oil adjusts human endocrine system in preparation, in the food of sebaceous cyst, drug Application, it is found that mandarin tree fruit volatile oil can pass through inhibit prostaglandin F_2αSecretion improves prostaglandin E₂Secretion, drop Low inflammatory factor expression is horizontal, improves antioxidant ability of organism, adjusts human endocrine system, stimulates the hormone point of internal body of gland Recurrence normal level is secreted, thus sebaceous cyst.

Preferably, the citrus fruits be sweet orange, fingered citron, shatian pomelo, grape fruit, loose-skin orange appoint one or more Combination is constituted.

Preferably, using extraction by steam distillation and collecting volatile oil, then after the pericarp stripping and slicing of citrus fruits Dehydration, obtains citrus fruits volatile oil.

Preferably, the food, drug use capsule, tablet or pressed candy or gel candy form.

A kind of food prepared by citrus fruits volatile oil, drug, it is characterised in that: volatilize including citrus fruits Oil.The food, drug purposes be adjust human endocrine system, be used for sebaceous cyst.

Preferably, citrus fruits volatile oil is contained in citrus fruits volatile oil powdered oil or citrus fruits are waved In hair oil tablet.

Preferably, further including filler, lubricant, preservative, sweetener, disintegrating agent, adhesive, plasticizer, dilution One of agent, glidant, colorant, solubilizer, dispersing agent, wetting agent, surfactant or multiple combinations.

Preferably, filler includes dextrin, cyclodextrin and starch；Sweetener includes lactose, xylitol and D-sorbite； Lubricant includes magnesium stearate；Preservative includes sodium benzoate；Disintegrating agent includes hydroxypropyl cellulose；Diluent includes sweet dew Alcohol, microcrystalline cellulose, lactose, cornstarch；Wetting agent includes polysorbate；Plasticizer includes repefral, sweet Oily diacetate, 1,2- propylene glycol, glycerol；Surfactant includes ethyl alcohol, propolis.

Preferably, the drug is by as follows at being grouped as: citrus fruits volatile oil powdered oil 1-40 parts by weight, ring Dextrin 5-30 parts by weight, starch 5-40 parts by weight, dextrin 5-30 parts by weight, lactose 5-60 parts by weight, xylitol 5-60 parts by weight, D-sorbite 5-60 parts by weight, magnesium stearate 0.1-4 parts by weight, sodium benzoate 0.1-0.2 parts by weight, hydroxypropyl cellulose 2-10 Parts by weight.

Preferably, the drug is by as follows at being grouped as: 30 parts by weight of citrus fruits volatile oil powdered oil, ring paste Smart 25 parts by weight, 20 parts by weight of starch, 5 parts by weight of dextrin, 10 parts by weight of lactose, 15 parts by weight of xylitol, 15 weight of D-sorbite Measure part, 0.8 parts by weight of magnesium stearate, 0.1 parts by weight of sodium benzoate, 5 parts by weight of hydroxypropyl cellulose.

Preferably, the preparation process of citrus fruits volatile oil powdered oil is as follows: citrus fruits volatile oil, octene After base succinic acid starch ester solution mixes in proportion, high speed shear, homogeneous under high pressure prepares citrus by the method for spray drying Belong to fruit volatile oil powdered oil.

Preferably, spray drying condition is 190 DEG C of inlet air temperature, 90-100 DEG C of leaving air temp, sample introduction speed is 30mL/ Min, centrifugal atomizer revolving speed are 20000r/min.

Preferably, citrus fruits volatile oil, starch octenyl succinate anhydride solution are mixed by the mass ratio of 1:4.

Compared with prior art, the present invention having the following advantages that and effect: citrus plant volatilizees oil food and drug Exploitation, can make the pericarp of citrus fruits be fully used, avoid the waste of resource, furthermore current sebaceous cyst medicine Object can only perhaps inhibit drug resistance that is ailing or will increase pathogen, reduce the service efficiency of antibiotic.

Specific embodiment

Below by embodiment, the present invention is described in further detail, following embodiment be explanation of the invention and The invention is not limited to following embodiments.