改进的免疫原性测定法
阅读说明:本技术 改进的免疫原性测定法 (Improved immunogenicity assays ) 是由 安内利斯·科登斯 维尔勒·斯诺尔克 玛丽-安格·比斯 卡罗·布东 于 2018-03-29 设计创作,主要内容包括:本发明涉及改进的免疫原性测定和用于进行该测定的方法。特别地,本发明涉及能够区分中和性抗药物抗体和非中和性抗药物抗体的改进的免疫原性测定。更特别地,本发明涉及改进的免疫原性测定,其允许在样品中检测和/或测定中和性抗药物抗体(的量和/或浓度),甚至在存在非中和性抗药物抗体的情况下。(The present invention relates to improved immunogenicity assays and methods for performing the assays. In particular, the invention relates to improved immunogenicity assays capable of distinguishing neutralizing anti-drug antibodies from non-neutralizing anti-drug antibodies. More particularly, the present invention relates to an improved immunogenicity assay which allows the detection and/or determination of (the amount and/or concentration of) neutralizing anti-drug antibodies in a sample, even in the presence of non-neutralizing anti-drug antibodies.)
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