阅读说明：本技术 一种鼻腔给药干粉递送装置 (Nasal cavity administration dry powder delivery device ) 是由 郭刚 郑奇军 张亚 佟振博 秦旭 于 2021-08-19 设计创作，主要内容包括：本发明公开一种鼻腔给药干粉递送装置,包括壳体,壳体内部竖直设置有通道,在通道中设置有托盘,托盘底部设置有推送组件,推送组件用于推动托盘在通道中滑动并限制托盘在通道中的位置,在通道两侧的壳体上分别设置有刺针组件,刺针组件用于刺破放置在托盘上的药物胶囊；在刺针组件上方的通道周围设置有气仓,在壳体上设置与气仓连通的吹嘴,在气仓上方设置有旋风分离槽,气仓通过左出气口和右出气口与旋风分离槽连通,旋风分离槽的中心处与通道连通,在壳体顶部设置与旋转分离槽连通的鼻口；本发明提高干粉药物在鼻腔内的递送效率,提高药物的生物利用度。(The invention discloses a nasal cavity administration dry powder delivery device, which comprises a shell, wherein a channel is vertically arranged in the shell, a tray is arranged in the channel, a pushing assembly is arranged at the bottom of the tray and used for pushing the tray to slide in the channel and limiting the position of the tray in the channel, puncture needle assemblies are respectively arranged on the shell at two sides of the channel and used for puncturing a medicine capsule placed on the tray; an air bin is arranged around the channel above the pricking pin component, a blowing nozzle communicated with the air bin is arranged on the shell, a cyclone separation groove is arranged above the air bin, the air bin is communicated with the cyclone separation groove through a left air outlet and a right air outlet, the center of the cyclone separation groove is communicated with the channel, and a nose opening communicated with the rotary separation groove is arranged at the top of the shell; the invention improves the delivery efficiency of the dry powder medicament in the nasal cavity and improves the bioavailability of the medicament.)

1. A dry powder delivery device for nasal administration is characterized by comprising a shell, wherein a channel is vertically arranged in the shell, a tray is arranged in the channel, a pushing assembly is arranged at the bottom of the tray and used for pushing the tray to slide in the channel and limiting the position of the tray in the channel, and puncture needle assemblies are respectively arranged on the shell at two sides of the channel and used for puncturing a medicine capsule placed on the tray; an air bin is arranged around the channel above the pricking pin component, a blowing nozzle communicated with the air bin is arranged on the shell, a cyclone separation groove is arranged above the air bin, the air bin is communicated with the cyclone separation groove through a left air outlet and a right air outlet, the center of the cyclone separation groove is communicated with the channel, and a nose opening communicated with the rotary separation groove is arranged at the top of the shell.

2. The nasal delivery dry powder delivery device of claim 1, wherein the pushing assembly comprises a stop collar, a stop shaft and a push rod; the vertical setting of spacing axle is at the interior bottom of casing, the stop collar slides and cup joints on spacing epaxially, and the top and the tray bottom of stop collar are connected, the one end and the stop collar of push rod are connected, and the other end extends to the casing outside, is formed with the bar hole that supplies the push rod to remove on the casing.

3. The dry powder delivery device for nasal administration of claim 2, wherein the pushing assembly further comprises a limiting rod and a return spring, the top end of the return spring is connected with the bottom end of the limiting sleeve, the bottom end of the return spring is connected with the inner bottom of the shell, and the return spring is sleeved on the limiting shaft; the shell is provided with an initial limiting hole and a termination limiting hole, one end of the limiting rod is connected with the limiting sleeve, and the other end of the limiting rod is clamped in the initial limiting hole or the termination limiting hole.

4. A dry powder delivery device for nasal administration according to claim 3, wherein a return button is provided on the outer side of the casing, one end of the return button is connected with the outer side of the casing, and the other end of the return button corresponds to the stop limit hole and is provided with a protruding structure for extending into the stop limit hole.

5. The dry powder delivery device for nasal administration of claim 1, wherein the pricking pin assembly comprises a button sleeve and a pricking pin, the pricking pin is arranged along the axis of the button sleeve, the tail end of the pricking pin is connected with the inner bottom of the button sleeve, the tip of the pricking pin extends to the outer side of the opening of the button sleeve, a groove body matched with the button sleeve is formed on the shell, the button sleeve is slidably connected to the groove body, the opening of the button sleeve is located inside the groove body, the bottom of the button sleeve is located outside the groove body, and a through hole for the tip of the pricking pin to penetrate through and enter the channel is formed in the bottom of the groove body.

6. The dry powder delivery device for nasal administration of claim 5, wherein the spike assembly further comprises a return spring, the return spring is sleeved on the spike, one end of the return spring is connected with the inner bottom of the groove body, and the other end of the return spring is connected with the inner bottom of the button sleeve.

7. The dry powder delivery device for nasal administration of claim 1, wherein the air flow paths at the center of the cyclone groove and at both sides of the cyclone groove communicating with the left air outlet and the right air outlet are not in the same line.

8. The dry powder delivery device for nasal administration of claim 1, wherein a flip cover is rotatably connected to the top of the housing, the nose opening is arranged on the flip cover, a plurality of through holes are arranged on the flip cover corresponding to the inside of the nose opening, and the plurality of through holes are arranged in an array.

9. The dry powder delivery device for nasal administration of claim 1, wherein the tray is provided with a limiting groove for limiting the position of the medicament capsule.

10. A dry powder delivery device for nasal administration according to claim 1 or 9, wherein the contact surface of the tray with the centre of the cyclonic separation groove is a stepped structure.

Technical Field

The invention relates to a nasal administration dry powder delivery device, and belongs to the technical field of nasal administration.

Background

The nasal administration is a mode of administration that the medicine is directly delivered into the nasal cavity through the nostrils, the medicine particles are firstly deposited on a certain specific area on the inner surface of the nasal cavity and then reach the action part of the medicine through a mucous layer and a mucous epithelial cell layer so as to treat local diseases of the nasal cavity and brain and systemic diseases; the traditional nasal administration is generally used for treating nasal cavity local diseases (rhinitis, nasal polyp, nasosinusitis and the like) and after nasal cavity operation, and directly delivers the medicine to the nasal cavity focus, so that the medicine can not only play a better drug effect, but also reduce the toxic and side effects caused by the medicine reaching the tissues of the whole body through blood circulation; in recent years, novel nasal administration has also been used for the treatment of brain and systemic diseases; for brain diseases, due to the existence of blood brain barrier, the conventional administration routes (intravenous injection, oral administration, intramuscular injection and the like) cause that drug molecules are difficult to enter the brain through blood circulation, and limit the treatment effect of the brain diseases (Alzheimer disease, Parkinson disease, epilepsy and the like); a large number of researches show that the nasal mucosa and the brain have direct nose-brain access, and the medicine can directly reach the brain through the nose-brain access, so that the limitation of a blood brain barrier is avoided, and a new method is provided for treating brain diseases; because the lower layer of epithelial cells of the nasal mucosa has rich capillaries and rich blood flow, drug molecules can be absorbed by the nasal mucosa to enter the capillaries and then enter the blood circulation to treat systemic diseases, such as the nasal cavity delivering insulin to treat diabetes and the like; nasal administration has the advantages of avoiding the first pass effect of the liver, improving the effectiveness of the medicine entering the brain, improving the bioavailability and the like, and is concerned by more and more researchers; the nasal cavity drug delivery device has vital function to the bioavailability of the medicine, especially delivers to the position of smelly region and is used for brain disease treatment, but traditional nasal cavity drug delivery dry powder device delivers the efficiency not high, in order to solve this problem, this patent proposes a novel delivery device for improve the delivery efficiency of dry powder medicine in the nasal cavity, improve the bioavailability of medicine.

Disclosure of Invention

The invention aims to solve the problems in the prior art and provides a dry powder delivery device for nasal administration, which is used for improving the delivery efficiency of dry powder medicines in nasal cavities and improving the bioavailability of the medicines.

In order to achieve the above object, the present invention adopts the following technical solutions:

a dry powder delivery device for nasal administration comprises a shell, wherein a channel is vertically arranged in the shell, a tray is arranged in the channel, a pushing assembly is arranged at the bottom of the tray and used for pushing the tray to slide in the channel and limiting the position of the tray in the channel, and pricking needle assemblies are respectively arranged on the shell at two sides of the channel and used for pricking a medicine capsule placed on the tray; an air bin is arranged around the channel above the pricking pin component, a blowing nozzle communicated with the air bin is arranged on the shell, a cyclone separation groove is arranged above the air bin, the air bin is communicated with the cyclone separation groove through a left air outlet and a right air outlet, the center of the cyclone separation groove is communicated with the channel, and a nose opening communicated with the rotary separation groove is arranged at the top of the shell.

As a further preferred aspect of the present invention, the pushing assembly includes a position-limiting sleeve, a position-limiting shaft and a push rod; the limiting shaft is vertically arranged at the inner bottom of the shell, the limiting sleeve is sleeved on the limiting shaft in a sliding mode, the top end of the limiting sleeve is connected with the bottom of the tray, one end of the push rod is connected with the limiting sleeve, the other end of the push rod extends to the outer side of the shell, and a strip-shaped hole for the push rod to move is formed in the shell; the position of the tray in the channel is adjusted by pushing the limit sleeve through the push rod.

As a further preferred option of the invention, the pushing assembly further comprises a limiting rod and a return spring, the top end of the return spring is connected with the bottom end of the limiting sleeve, the bottom end of the return spring is connected with the inner bottom of the shell, and the return spring is sleeved on the limiting shaft; an initial limiting hole and a stop limiting hole are formed in the shell, one end of the limiting rod is connected with the limiting sleeve, and the other end of the limiting rod is clamped in the initial limiting hole or the stop limiting hole; in an initial state, the other end of the limiting rod is clamped in the initial limiting hole, after the limiting sleeve is pushed upwards through the push rod, the other end of the limiting rod slides out of the initial limiting hole and is clamped in the stop limiting hole, and at the moment, the return spring is stretched; when the other end of the limiting rod clamped in the stopping limiting hole is ejected out, the limiting sleeve is pulled back to the initial position downwards by the return spring under the action of the contraction elastic force of the return spring.

As a further preferred aspect of the present invention, a return button is disposed on an outer side surface of the housing, one end of the return button is connected to the outer side surface of the housing, and the other end of the return button corresponds to the stop limit hole and is provided with a protrusion structure for extending into the stop limit hole; the return button is used for ejecting the end part of the limiting rod in the limiting hole; when the device is operated, the return button is pressed, the protruding structure arranged at the other end of the return button extends into the stopping limiting hole, and the protruding structure ejects out the end part of the limiting rod clamped in the stopping limiting hole.

As a further optimization of the invention, the pricking pin component comprises a button sleeve and a pricking pin, the pricking pin is arranged along the axis of the button sleeve, the tail end of the pricking pin is connected with the inner bottom of the button sleeve, the tip of the pricking pin extends to the outer side of the opening of the button sleeve, a groove body matched with the button sleeve is formed on the shell, the button sleeve is connected to the groove body in a sliding manner, the opening of the button sleeve is positioned in the groove body, the bottom of the button sleeve is positioned outside the groove body, and a through hole for the tip of the pricking pin to penetrate through and enter the channel is formed in the bottom of the groove body; by pressing the button sleeve the tip of the spike enters the channel and pierces the medicament capsule.

As a further optimization of the invention, the puncture needle assembly further comprises a return spring, the return spring is sleeved on the puncture needle, one end of the return spring is connected with the inner bottom of the groove body, and the other end of the return spring is connected with the inner bottom of the button sleeve; the tip of the puncture needle enters the channel and punctures the medicine capsule by pressing the button sleeve, and at the moment, the return spring is compressed; after the button sleeve is loosened, the reset spring releases elasticity to push the button sleeve to reset, so that the sharp end of the puncture needle is withdrawn from the medicine capsule and the channel.

As a further preferable aspect of the present invention, the airflow paths on both sides of the center of the cyclone separation tank, which communicate with the left and right air outlets, are not on the same straight line; namely, the two airflow paths are not oppositely arranged, wherein one airflow path is close to the front side of the shell, and the other airflow path is close to the rear side of the shell; the airflow in the air bin is divided into two air flows which enter the cyclone separation groove through the left air outlet and the right air outlet respectively, and the two air flows drive the medicine capsule to rotate, so that the medicine powder in the medicine capsule is thrown out under the action of centrifugal force.

As a further preferred aspect of the present invention, the top of the housing is rotatably connected with a flip, the nose opening is disposed on the flip, the flip corresponding to the inside of the nose opening is provided with a plurality of through holes, and the plurality of through holes are arranged in an array; after the flip cover is opened, the used medicine capsule can be taken out, a new medicine capsule can be put in, and the flip cover is closed so as to be used repeatedly.

As a further preferred aspect of the present invention, the tray is provided with a limiting groove for limiting the medicament capsule; so that the medicine capsule can be placed according to the shape of the limit groove.

As a further preferred of the present invention, the contact surface of the tray and the center of the cyclone separating groove is a step structure; the sealing performance of the tray in contact with the center of the cyclone separating groove is improved, and the air flow leakage amount in the cyclone separating groove is reduced.

The invention has the advantages that:

(1) firstly, the invention designs a pushing mode for the medicine capsule; a channel is vertically arranged in the shell, a tray is arranged in the channel, a pushing assembly is arranged at the bottom of the tray and used for pushing the tray to slide in the channel and limiting the position of the tray in the channel, so that the pushing of the medicine capsule is realized;

(2) secondly, the invention designs a puncturing mode for the medicine capsule; the shell on the two sides of the channel is respectively provided with a pricking pin component which is used for pricking the medicine capsule placed on the tray and can automatically reset, so that the medicine capsule can be pricked;

(3) finally, the invention designs the airflow path; the air bin and the cyclone separating groove are arranged inside the shell, and the air flow path is designed, so that in the air blowing process, the two air flows are utilized to drive the medicine capsule to rotate, the medicine powder in the medicine capsule is thrown out under the action of centrifugal force, and the thrown medicine powder flows into the nasal cavity through the nasal opening along with the air flow, so that the delivery efficiency of dry powder medicines in the nasal cavity is improved, and the bioavailability of the medicines is improved.

Drawings

Fig. 1 is a schematic perspective view of a first embodiment of the present invention;

FIG. 2 is a schematic front view of the first embodiment of the present invention;

FIG. 3 is a schematic top view of the first embodiment of the present invention;

FIG. 4 is a schematic view of the internal structure of a pallet in an initial position according to an embodiment of the present invention;

FIG. 5 is a schematic view of a spike assembly for puncturing a medication capsule in accordance with an embodiment of the present invention;

FIG. 6 is a first schematic view of a medicine capsule pushed into the cyclone separation tank according to an embodiment of the present invention;

FIG. 7 is a schematic structural diagram II illustrating a medicine capsule pushed into the cyclone separation tank according to the first embodiment of the present invention;

FIG. 8 is a schematic top view of the housing with the top removed according to one embodiment of the present invention;

FIG. 9 is a schematic perspective view of a second embodiment of the present invention;

FIG. 10 is a schematic side view of the second embodiment of the present invention;

FIG. 11 is a schematic top view of the second embodiment of the present invention;

the meaning of the reference symbols in the figures:

1-shell, 2-channel, 3-tray, 4-medicine capsule, 5-air chamber, 6-blowing nozzle, 7-cyclone separation groove, 8-left air outlet, 9-right air outlet, 10-nose opening, 11-limiting sleeve, 12-limiting shaft, 13-push rod, 14-strip-shaped hole, 15-limiting rod, 16-return spring, 17-initial limiting hole, 18-termination limiting hole, 19-return button, 20-limiting groove, 21-button sleeve, 22-puncture needle, 23-return spring, 24-turnover cover and 25-through hole.

Detailed Description

The invention is described in detail below with reference to the figures and the embodiments.

Example one

As shown in fig. 1-8, the present embodiment is a nasal cavity administration dry powder delivery device, which comprises a housing 1, a channel 2 is vertically arranged inside the housing 1, a tray 3 is arranged in the channel 2, a pushing assembly is arranged at the bottom of the tray 3, the pushing assembly is used for pushing the tray 3 to slide in the channel 2 and limiting the position of the tray 3 in the channel 2, and lancet assemblies are respectively arranged on the housing 1 at two sides of the channel 2, and are used for puncturing a medicine capsule 4 placed on the tray 3; an air bin 5 is arranged around the channel 2 above the pricking pin assembly, a blowing nozzle 6 communicated with the air bin 5 is arranged on the shell 1, a cyclone separation groove 7 is arranged above the air bin 5, the air bin 5 is communicated with the cyclone separation groove 7 through a left air outlet 8 and a right air outlet 9, the center of the cyclone separation groove 7 is communicated with the channel 2, and a nose opening 10 communicated with the rotary separation groove 7 is arranged at the top of the shell 1.

In this embodiment, the pushing assembly includes a limiting sleeve 11, a limiting shaft 12 and a push rod 13; the limiting shaft 12 is vertically arranged at the inner bottom of the shell 1, the limiting sleeve 11 is sleeved on the limiting shaft 12 in a sliding mode, the top end of the limiting sleeve 11 is connected with the bottom of the tray 3, one end of the push rod 13 is connected with the limiting sleeve 11, the other end of the push rod extends to the outer side of the shell 1, and a strip-shaped hole 14 for the push rod 13 to move is formed in the shell 1; the position limiting sleeve 11 is pushed by the push rod 13, so that the position of the tray 3 in the channel 2 is adjusted; the pushing assembly further comprises a limiting rod 15 and a return spring 16, the top end of the return spring 16 is connected with the bottom end of the limiting sleeve 11, the bottom end of the return spring 16 is connected with the inner bottom of the shell 1, and the return spring 16 is sleeved on the limiting shaft 12; an initial limiting hole 17 and a stop limiting hole 18 are arranged on the shell 1, one end of a limiting rod 15 is connected with the limiting sleeve 11, and the other end of the limiting rod is clamped in the initial limiting hole 17 or the stop limiting hole 18; in an initial state, the other end of the limiting rod 15 is clamped in the initial limiting hole 17, after the limiting sleeve 11 is pushed upwards through the push rod 13, the other end of the limiting rod 15 slides out of the initial limiting hole 17 and is clamped in the stopping limiting hole 18, and at the moment, the return spring 16 is stretched; when the other end of the limiting rod 15 clamped in the stopping limiting hole 18 is ejected, the limiting sleeve 11 is pulled back to the initial position downwards by the return spring 16 under the action of the contraction elastic force of the return spring 16.

In the embodiment, a return button 19 is arranged on the outer side surface of the shell 1, one end of the return button 19 is connected with the outer side surface of the shell 1, and the other end of the return button 19 corresponds to the stop limit hole 18 and is provided with a convex structure for extending into the stop limit hole 18; the return button 19 is used for ejecting the end part of the limiting rod 15 in the limiting hole 18; when the device is operated, the return button 19 is pressed, so that the convex structure arranged at the other end of the return button 19 extends into the stopping limiting hole 18, and the end part of the limiting rod 15 clamped in the stopping limiting hole 18 is ejected out by the convex structure.

In this embodiment, the pricking pin assembly comprises a button sleeve 21 and a pricking pin 22, the pricking pin 22 is arranged along the axis of the button sleeve 21, the tail end of the pricking pin 22 is connected with the inner bottom of the button sleeve 21, the tip of the pricking pin 22 extends to the outer side of the opening of the button sleeve 21, a groove body matched with the button sleeve 21 is formed on the shell 1, the button sleeve 21 is slidably connected to the groove body, the opening of the button sleeve 21 is located inside the groove body, the bottom of the button sleeve 21 is located outside the groove body, and a through hole for the tip of the pricking pin 22 to penetrate through and enter the channel 2 is formed in the bottom of the groove body; by pressing the button sleeve 21, the tip of the piercing needle 22 enters the channel 2 and pierces the medicament capsule 4; the puncture needle assembly further comprises a return spring 23, the return spring 23 is sleeved on the puncture needle 22, one end of the return spring 23 is connected with the inner bottom of the groove body, and the other end of the return spring 23 is connected with the inner bottom of the button sleeve 21; by pressing the button sleeve 21, the tip of the spike 22 enters the channel 2 and pierces the medicament capsule 4, at which point the return spring 23 is compressed; after releasing the button sleeve 21, the return spring 23 releases its spring force to push the button sleeve 21 to return, so that the tip of the puncture needle 22 is withdrawn from the medicine capsule 4 and the channel 2.

In the embodiment, the air flow paths of the two sides of the center of the cyclone separation groove 7, which are communicated with the left air outlet 8 and the right air outlet 9, are not on the same straight line; namely, two air flow paths are not oppositely arranged, wherein one air flow path is close to the front side of the shell 1, and the other air flow path is close to the rear side of the shell 1; the air current in the air bin 5 divides into two strands and gets into the cyclone 7 through left gas outlet 8 and right gas outlet 9 respectively, and two strands of air currents drive medicine capsule 4 rotatory, make the powder in the medicine capsule 4 throw away under the effect of centrifugal force.

In this embodiment, the tray 3 is provided with a limiting groove 20 for limiting the medicine capsule 4; the medicine capsule 4 can be placed according to the shape of the limiting groove 20; the axial ends of the limiting groove 20 correspond to the two needle assemblies, so that the needle assemblies can conveniently puncture the medicine capsules 4 in the limiting groove 20.

In the embodiment, the contact surface of the tray 3 and the center of the cyclone separation groove 7 is of a step structure; the sealing performance when the tray 3 contacts with the center of the cyclone separating groove 7 is improved, and the air flow leakage amount in the cyclone separating groove 7 is reduced.

Example two

As shown in fig. 9-11 and referring to fig. 4-8, the present embodiment is similar to the embodiment, except that a flip cover 24 is rotatably connected to the top of the housing 1 in the present embodiment, the nose opening 10 is disposed on the flip cover 24, a plurality of through holes 25 are disposed on the flip cover 24 corresponding to the inside of the nose opening 10, and the plurality of through holes 25 are arranged in an array; after the flip cover 24 is opened, the used medicine capsule 4 can be taken out, a new medicine capsule 4 can be put in, and the flip cover 24 is closed so as to be convenient for repeated use.

The two embodiments described above are used as follows:

the capsule 4 is placed on the tray 3, by pressing the button sleeve 21, the tip of the piercing needle 22 enters the channel 2 and pierces the capsule 4, at which point the return spring 23 is compressed; after releasing the button sleeve 21, the return spring 23 releases the elastic force to push the button sleeve 21 to return, so that the tip of the puncture needle 22 is withdrawn from the medicine capsule 4 and the channel 2; the limiting sleeve 11 is pushed upwards through the push rod 13, the limiting sleeve 11 drives the tray 3 to move upwards, the medicine capsules 4 on the tray 3 enter the cyclone separation groove 7 after the tray 3 contacts the center of the cyclone separation groove 7, in the process, the other end of the limiting rod 15 slides out of the initial limiting hole 17 and is clamped in the stopping limiting hole 18, and at the moment, the return spring 16 is stretched; then the nasal opening 10 is inserted into the nasal cavity, the mouth starts to blow after holding the mouthpiece 6, the air flow enters the air chamber 5 from the mouthpiece 6, the air flow in the air chamber 5 is divided into two air flows which respectively enter the cyclone separation groove 7 through the left air outlet 8 and the right air outlet 9, the two air flows drive the medicine capsule 4 to rotate, the medicine powder in the medicine capsule 4 is thrown out under the action of centrifugal force, the thrown medicine powder flows into the nasal cavity through the nasal opening 10 along with the air flow, and the nasal cavity administration delivery is completed through repeated blowing; after the administration is finished, the return button 19 is pressed, so that a convex structure arranged at the other end of the return button 19 extends into the stop limiting hole 18, the end part of the limiting rod 15 clamped in the stop limiting hole 18 is ejected out by the convex structure, under the action of the contraction elastic force of the return spring 16, the limiting sleeve 11 is pulled back to the initial position downwards by the return spring 16, and the limiting sleeve 11 drives the tray 3 to move downwards to the initial position; if the top of the shell 1 is rotatably connected with the flip cover 24, the flip cover 24 is opened, the used medicine capsule 4 is taken out, a new medicine capsule 4 can be put in, and the flip cover 24 is closed, so that the medicine capsule can be used repeatedly.

The invention has the following beneficial effects:

(1) firstly, the invention designs a pushing mode for the medicine capsule; a channel is vertically arranged in the shell, a tray is arranged in the channel, a pushing assembly is arranged at the bottom of the tray and used for pushing the tray to slide in the channel and limiting the position of the tray in the channel, so that the pushing of the medicine capsule is realized;

(2) secondly, the invention designs a puncturing mode for the medicine capsule; the shell on the two sides of the channel is respectively provided with a pricking pin component which is used for pricking the medicine capsule placed on the tray and can automatically reset, so that the medicine capsule can be pricked;

(3) finally, the invention designs the airflow path; the air bin and the cyclone separating groove are arranged inside the shell, and the air flow path is designed, so that in the air blowing process, the two air flows are utilized to drive the medicine capsule to rotate, the medicine powder in the medicine capsule is thrown out under the action of centrifugal force, and the thrown medicine powder flows into the nasal cavity through the nasal opening along with the air flow, so that the delivery efficiency of dry powder medicines in the nasal cavity is improved, and the bioavailability of the medicines is improved.

In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are used only for convenience in describing the present invention and for simplicity in description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present invention.

In the description of the present invention, it should be noted that the terms "mounted," "connected," and "disposed" are to be construed broadly and may be, for example, fixedly connected, disposed, detachably connected, disposed, or integrally connected and disposed unless otherwise explicitly stated or limited; can be mechanically or electrically connected; the two elements can be directly connected, indirectly connected through an intermediate medium, or communicated with each other inside; the specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

The foregoing shows and describes the general principles, principal features and advantages of the invention; it should be understood by those skilled in the art that the above embodiments do not limit the present invention in any way, and all technical solutions obtained by using equivalent alternatives or equivalent variations fall within the scope of the present invention.