阅读说明：本技术 一种治疗胆囊癌的纯中药透皮擦剂及其制备方法 (Pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer and preparation method thereof ) 是由 吴婧婷 李少龙 于 2021-09-30 设计创作，主要内容包括：本发明公开了一种治疗胆囊癌的纯中药透皮擦剂,包括下列重量份的原料：猪殃殃9-12份,天葵子12-15份,凤尾草9-12份,天胡荽9-12份,半边莲12-15份,八月扎9-12份,灵芝草9-12份；本发明还公开了一种治疗胆囊癌纯中药透皮擦剂的制备方法,包括以下步骤：S1、将猪殃殃,天葵子,凤尾草,天胡荽,半边莲,八月扎,灵芝草按所述的重量份放入石臼中,捣烂成粉；S2、将捣烂的混合粉放入50-100重量份的75％酒精内泡制20-25天即可使用。本发明制作简单,外用擦敷方便,纯中药制剂毒副作用小、使用安全、疗效可靠。(The invention discloses a pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer, which comprises the following raw materials in parts by weight: 9-12 parts of cleavers, 12-15 parts of muskroot-like semiaquilegia root, 9-12 parts of Chinese brake herb, 9-12 parts of lawn pennywort herb, 12-15 parts of Chinese lobelia herb, 9-12 parts of akebia fruit and 9-12 parts of glossy ganoderma; the invention also discloses a preparation method of the pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer, which comprises the following steps: s1, putting cleavers, muskroot-like semiaquilegia root, pteris multifida, lawn pennywort herb, Chinese lobelia herb, akebia fruit and ganoderma lucidum into a stone mortar according to the weight parts, and pounding the cleavers into powder; s2, soaking the mashed mixed powder in 50-100 parts by weight of 75% alcohol for 20-25 days. The invention has simple preparation, convenient external application, small toxic and side effect of the pure Chinese medicinal preparation, safe use and reliable curative effect.)

1. A pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer is characterized by comprising the following raw materials in parts by weight: 9-12 parts of cleavers, 12-15 parts of muskroot-like semiaquilegia root, 9-12 parts of Chinese brake herb, 9-12 parts of lawn pennywort herb, 12-15 parts of Chinese lobelia herb, 9-12 parts of akebia fruit and 9-12 parts of glossy ganoderma.

2. The pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer according to claim 1, which is characterized by comprising the following raw materials in parts by weight: cleavers 9 parts, muskroot-like semiaquilegia root 12 parts, phoenix-tail fern 9 parts, lawn pennywort 9 parts, Chinese lobelia 12 parts, akebia fruit 9 parts and glossy ganoderma 9 parts.

3. The pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer according to claim 1, which is characterized by comprising the following raw materials in parts by weight: cleavers 9 parts, muskroot-like semiaquilegia root 13 parts, Chinese brake herb 11 parts, lawn pennywort herb 12 parts, Chinese lobelia herb 11 parts, akebia fruit 10 parts and glossy ganoderma 9 parts.

4. The preparation method of the pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer according to any one of claims 1 to 3, which is characterized by comprising the following steps:

s1, putting cleavers, muskroot-like semiaquilegia root, pteris multifida, lawn pennywort herb, Chinese lobelia herb, akebia fruit and ganoderma lucidum into a stone mortar according to the weight parts, and pounding the cleavers into powder;

s2, soaking the mashed mixed powder in 50-100 parts by weight of alcohol for 20-25 days.

5. The preparation method of the pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer according to claim 4, wherein the alcohol concentration is 75%.

Technical Field

The invention belongs to an external traditional Chinese medicine liniment and a preparation method thereof, and particularly relates to a pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer and a preparation method thereof.

Background

Gallbladder cancer is a malignant tumor formed in epithelial cells of gallbladder mucosa, people with irregular work and rest, oily food addicted and cholelithiasis are main factors for causing the gallbladder cancer, early symptoms of the gallbladder cancer are not obvious, most patients find the middle and late stages as soon as the gallbladder cancer is detected, the existing treatment method comprises operation treatment, traditional Chinese medicine and western medicine treatment, the operation treatment risk is large and easy to repeat, the traditional Chinese medicine treatment effect is slow, the treatment period is long, the western medicine treatment has large toxic and side effects, and the drug resistance is easy to generate.

The treatment effect of the method is not ideal, and the problem to be solved is to find a treatment method which can remove the disease root and is not easy to repeat.

Disclosure of Invention

In view of the above technical problems, a first object of the present invention is to provide a pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer, which adopts pure traditional Chinese medicine preparations to replace the existing western medicine or traditional Chinese medicine therapy, and in order to achieve the purpose, the present invention adopts the following technical scheme:

a pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer comprises the following raw materials in parts by weight: 9-12 parts of cleavers, 12-15 parts of muskroot-like semiaquilegia root, 9-12 parts of Chinese brake herb, 9-12 parts of lawn pennywort herb, 12-15 parts of Chinese lobelia herb, 9-12 parts of akebia fruit and 9-12 parts of glossy ganoderma.

Preferably, the feed comprises the following raw materials in parts by weight: cleavers 9 parts, muskroot-like semiaquilegia root 12 parts, phoenix-tail fern 9 parts, lawn pennywort 9 parts, Chinese lobelia 12 parts, akebia fruit 9 parts and glossy ganoderma 9 parts.

Preferably, the feed comprises the following raw materials in parts by weight: cleavers 9 parts, muskroot-like semiaquilegia root 13 parts, Chinese brake herb 11 parts, lawn pennywort herb 12 parts, Chinese lobelia herb 11 parts, akebia fruit 10 parts and glossy ganoderma 9 parts.

The invention has the beneficial effects that: the pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer adopts pure traditional Chinese medicine preparations for external application treatment, replaces traditional Chinese medicine and western medicine treatment, and has the advantages of small toxic and side effects, difficulty in generating dependence and remarkable treatment effect.

The invention also provides a preparation method of the pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer, which comprises the following steps:

s1, putting cleavers, muskroot-like semiaquilegia root, pteris multifida, lawn pennywort herb, Chinese lobelia herb, akebia fruit and ganoderma lucidum into a stone mortar according to the weight parts, and pounding the cleavers into powder;

s2, soaking the mashed mixed powder in 50-100 parts by weight of alcohol for 20-25 days.

Preferably, the alcohol concentration is 75%, the alcohol concentration blending is 75%, the permeability is strong, the water of the bacterial protein is fully absorbed, the bacterial protein is dehydrated, denatured and solidified, the generation of bacteria is inhibited, and the sterilization capability is strong.

The invention has the beneficial effects that: a Chinese medicinal liniment for treating gallbladder cancer is prepared by grinding the raw materials into powder, soaking in 75% ethanol for 20-25 days, dissolving in ethanol, and mixing with ethanol to improve drug effect.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1

A pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer comprises the following raw materials in parts by weight: cleavers 9 parts, muskroot-like semiaquilegia root 12 parts, phoenix-tail fern 9 parts, lawn pennywort 9 parts, Chinese lobelia 12 parts, akebia fruit 9 parts and glossy ganoderma 9 parts.

A method for preparing a pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer comprises the following steps:

s1, putting cleavers, muskroot-like semiaquilegia root, pteris multifida, lawn pennywort herb, Chinese lobelia herb, akebia fruit and ganoderma lucidum into a stone mortar according to the weight parts, and pounding the cleavers into powder;

s2, the mashed mixed powder is put into 75 parts by weight of 75% alcohol to be soaked for 20 days.

Example 2

A pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer comprises the following raw materials in parts by weight: cleavers 9 parts, muskroot-like semiaquilegia root 13 parts, Chinese brake herb 11 parts, lawn pennywort herb 12 parts, Chinese lobelia herb 11 parts, akebia fruit 10 parts and glossy ganoderma 9 parts.

A method for preparing a pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer comprises the following steps:

s1, putting cleavers, muskroot-like semiaquilegia root, pteris multifida, lawn pennywort herb, Chinese lobelia herb, akebia fruit and ganoderma lucidum into a stone mortar according to the weight parts, and pounding the cleavers into powder;

s2, the mashed mixed powder is put into 75% alcohol with the weight portion of 80 to be soaked for 25 days.

Example 3

A pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer comprises the following raw materials in parts by weight: cleavers 12 parts, muskroot-like semiaquilegia root 15 parts, Chinese brake herb 12 parts, muskroot-like peucedanum root 12 parts, Chinese lobelia 15 parts, akebia fruit 12 parts and glossy ganoderma 10 parts.

A method for preparing a pure traditional Chinese medicine transdermal liniment for treating gallbladder cancer comprises the following steps:

s1, putting cleavers, muskroot-like semiaquilegia root, pteris multifida, lawn pennywort herb, Chinese lobelia herb, akebia fruit and ganoderma lucidum into a stone mortar according to the weight parts, and pounding the cleavers into powder;

s2, putting the mashed mixed powder into 85 parts by weight of 75% alcohol, and soaking for 22 days.

The using method comprises the following steps: the corresponding part is rubbed with the infused medicament three times a day, and 40 days are a course of treatment (under the guidance of a doctor, the acupuncture point rubbing effect is better).

Clinical experiments are as follows:

1. basic information

90 gallbladder cancer patients are randomly selected for investigation, the age distribution is 30-70 years, the disease course is longest 5 years and shortest 7 months, and most patients have symptoms of inappetence, nausea, vomiting, abdominal pain and unclear abdominal heaving.

2. Test method

Setting a control group 1, a control group 2 and an example group, wherein each group is randomly distributed with 30 persons, and each group of test cases are respectively treated by the corresponding drug for 40 days (namely one treatment course);

control group 1 was treated with traditional Chinese medicines, for example: ginsenoside Rh2 or acupuncture points;

control group 2 was treated with western medicines such as: fluorouracil, cisplatin;

in the examples, the Chinese medicinal liniment prepared from any one of the components of the examples 1 to 3 was applied to the acupoints three times a day.

3. Judgment of therapeutic effect

The curative effect judgment is as follows: three grades of cure, improvement and non-cure.

And (3) curing: the phenomena of inappetence, nausea, vomiting and abdominal pain disappear, and the abdominal bulge is eliminated.

Improvement: occasionally, there is a loss of appetite, nausea, vomiting, occasional abdominal pain and elimination of abdominal bumps.

The disease is not cured: the symptoms of inappetence, nausea and vomiting are not relieved, the abdominal pain is continuous, and the abdominal protuberance is not eliminated.

4. Therapeutic results

After one treatment cycle, the treatment was as follows for each group of patients:

the treatment results show that the curative effect of the example group is obviously higher than that of the control group 1 and the control group 2, the invention obviously improves the treatment effect on the cholecystitis, and the example group has no adverse symptoms during the treatment observation period and has no difference before the body condition is cured.

The above description is a preferred embodiment of the present invention, but the present invention should not be limited to the disclosure of the embodiment.

Therefore, it is intended that all equivalents and modifications which do not depart from the spirit of the invention disclosed herein are deemed to be within the scope of the invention.