一种测量心肌组织运动特征的非侵入性方法及系统
阅读说明:本技术 一种测量心肌组织运动特征的非侵入性方法及系统 (Non-invasive method and system for measuring myocardial tissue motion characteristics ) 是由 王翎 易成 何碧霞 谢鹏 于 2019-04-18 设计创作,主要内容包括:一种测量心肌组织运动特征的非侵入性方法,包括:传输生成的多个同步正交、不同频率的相位可控可调的周期性交流电流至生物体(20)内以产生多个不同频率的周期性交流电压信号;接收由生物体(20)内心脏组织(25)变化调制的交流电压信号,以获取生物体(20)的频率响应;根据频率响应计算心脏组织(25)的电阻和电容;根据电阻和电容估算心肌组织的运动特征。通过引入心肌细胞纵向平均长度,并且根据电容计算心肌细胞的纵向平均长度变化,给出心脏整体的纵向弹性的一种描述方法。提供了连续的、高采样率、非侵入性的方法来测量心肌组织在整个细胞层面上的运动,从而能够检测到心肌细胞更微小的异常变化。(A non-invasive method of measuring myocardial tissue motion characteristics, comprising: transmitting the generated plurality of synchronized orthogonal, phase controllable and adjustable periodic alternating currents of different frequencies into the living being (20) to generate a plurality of periodic alternating voltage signals of different frequencies; receiving an alternating voltage signal variably modulated by cardiac tissue (25) within the living being (20) to obtain a frequency response of the living being (20); calculating the resistance and capacitance of the cardiac tissue (25) from the frequency response; the motion characteristics of the myocardial tissue are estimated based on the electrical resistance and capacitance. A description is given of the longitudinal elasticity of the heart as a whole by introducing the longitudinal average length of the cardiomyocytes and calculating the change in the longitudinal average length of the cardiomyocytes from the capacitance. A continuous, high-sampling-rate, non-invasive method is provided to measure the motion of myocardial tissue at the whole cell level, thereby enabling the detection of more subtle abnormal changes in the myocardial cells.)
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