阅读说明：本技术 一种多功能细胞冻存温度探针固定装置 (Multi-functional cell cryopreserving temperature probe fixing device ) 是由 王瑞宁 于 2021-09-03 设计创作，主要内容包括：本发明涉及细胞冻存温度探针固定装置技术领域,具体揭示了一种多功能细胞冻存温度探针固定装置,包括底板、样本放置台、冻存放置架和空心圆杆；底板,样本放置台位于底板顶部,样本放置台位于底板顶部,空心圆杆位于底板顶部；本发明通过空心圆杆上设有螺纹孔,以及转动把手一端上有与空心圆杆上螺纹孔相匹配的螺纹,来控制探针在的冻存管内的最佳监测高度,可适用1.8ml,4.5ml等不同规格冻存管,从而使该多功能细胞冻存温度探针固定装置达到了结构合理、安全可靠的多功能细胞冻存温度探针固定装置,可用一种温度探针去测量,监控不同规格细胞载体的温度变化,消除无法固定探针进而导致探针在细胞载体内碰壁、触底的风险,提高操作精准性。(The invention relates to the technical field of cell cryopreservation temperature probe fixing devices, and particularly discloses a multifunctional cell cryopreservation temperature probe fixing device which comprises a bottom plate, a sample placing table, a cryopreservation placing frame and a hollow round rod, wherein the bottom plate is provided with a sample placing table; the sample placing table is positioned at the top of the bottom plate, the hollow round rod is positioned at the top of the bottom plate; according to the multifunctional cell cryopreservation temperature probe fixing device, the threaded hole is formed in the hollow round rod, the thread matched with the threaded hole in the hollow round rod is arranged at one end of the rotating handle, the optimal monitoring height of the probe in the cryopreservation tube is controlled, and the multifunctional cell cryopreservation temperature probe fixing device is suitable for cryopreservation tubes of different specifications such as 1.8ml and 4.5ml, so that the multifunctional cell cryopreservation temperature probe fixing device achieves a reasonable-structure, safe and reliable multifunctional cell cryopreservation temperature probe fixing device, can be used for measuring by using one temperature probe, monitoring the temperature change of cell carriers of different specifications, eliminates the risk that the probe cannot be fixed, and then the probe collides with the wall and touches the bottom in the cell carrier, and improves the operation accuracy.)

1. The utility model provides a multi-functional cell cryopreserving temperature probe fixing device which characterized in that: comprises a bottom plate (1), a sample placing table (6), a freezing storage rack (7) and a hollow round rod (2); the sample placing table (6) is positioned at the top of the bottom plate (1), the freezing and placing frame (7) is positioned at the top of the bottom plate (1), and the hollow round rod (2) is positioned at the top of the bottom plate (1); the device comprises a hollow round rod (2), wherein a limiting rod (4) is arranged on the hollow round rod (2), a rotating handle (3) is arranged on the outer wall of the hollow round rod (2), and a fixing block (5) is fixedly connected to the top of the limiting rod (4); the freezing rack (7), freezing rack (7) is put on one's body fixedly connected with and is rotated knob (8), it has lid (9) to rotate one side that knob (8) kept away from freezing rack (7).

2. The multifunctional cell cryopreservation temperature probe fixing device of claim 1, wherein: the hollow round bar is characterized in that a threaded hole is formed in the bar body of the hollow round bar (2), threads matched with the threaded hole are arranged at one end of the rotating handle (3), and the end, provided with the threads, of the rotating handle (3) is in threaded connection with the threaded hole.

3. The multifunctional cell cryopreservation temperature probe fixing device of claim 1, wherein: the shape of gag lever post (4) plane of looking down is circular, the diameter of gag lever post (4) plane of looking down is less than hollow round bar (2) internal diameter of plane of looking down, and gag lever post (4) sliding connection is in the inner chamber of hollow round bar (2).

4. The multifunctional cell cryopreservation temperature probe fixing device of claim 1, wherein: fixed block (5) are the mirror image mode opposition including two squares and are in the same place to one side of two squares is passed through the hinge and is rotated and link together, the preformed hole has been seted up to one side that the hinge was kept away from in fixed block (5), the screw thread through connection that fixed block (5) are close to the preformed hole has two bolts, and two squares have seted up semicircular groove on being close to the outer wall of one side each other.

5. The multifunctional cell cryopreservation temperature probe fixing device of claim 1, wherein: the sample placing table (6) comprises a square plate and a round bar, the square plate is located at the top of the round bar, anti-skidding lines are arranged on the sample placing table (6), and the sample placing table (6) is located at the central position between the fixed block (5) and the freezing storage placing frame (7) and is close to the position of the bottom of the fixed block (5).

6. The multifunctional cell cryopreservation temperature probe fixing device of claim 1, wherein: the freezing and storing rack (7) is located at the other end of the fixed block (5) on the bottom plate (1), and the freezing and storing rack (7) is located on the same straight line with the fixed block (5) and the midpoint of the sample placing table (6).

7. The multifunctional cell cryopreservation temperature probe fixing device of claim 1, wherein: one side of the box cover (9) close to the fixing block (5) is provided with a preformed hole for inserting the probe, and two sides of the bottom of the box cover (9) are fixedly connected with elastic elements (10).

8. The multifunctional cell cryopreservation temperature probe fixing device of claim 7, wherein: the bottom of the elastic element (10) is fixedly connected with a thin pressing plate (11), the thin pressing plate (11) is made of polycarbonate, and one side of the box cover (9) is movably connected with a fixing clamp (12).

9. The multifunctional cell cryopreservation temperature probe fixing device of claim 1, wherein: the frozen sample storage rack is characterized in that the bottom plate (1), the hollow round rod (2), the fixing block (5), the sample storage table (6), the frozen sample storage rack (7), the box cover (9), the rotating knob (8), the elastic element (10) and the thin pressing plate (11) are connected in a welding mode.

10. The multifunctional cell cryopreservation temperature probe fixing device of claim 1, wherein: the frozen sample storage rack is characterized in that the bottom plate (1), the hollow round rod (2), the fixing block (5), the frozen sample storage rack (7), the sample storage table (6), the box cover (9), the elastic element (10), the fixing clamp (12), the limiting rod (4), the rotating handle (3) and the rotating knob (8) are made of aluminum alloy.

Technical Field

The invention relates to the technical field of cell cryopreservation temperature probe fixing devices, in particular to a multifunctional cell cryopreservation temperature probe fixing device.

Background

With the rapid development of the cell cryopreservation technology, the temperature in cells at different stages is monitored by temperature probes in the current cell cryopreservation process so as to ensure that the cells are cooled according to a program and avoid the cells from being damaged. Temperature probes specially aiming at cell carriers of different specifications do not appear in the market, temperature probes of corresponding specifications are generally selected according to the cell carriers of different specifications in the industry, however, due to frequent replacement of different probes, recalibration is required in each replacement operation, manpower and material resources are wasted, repeated operation is carried out, and the operation method is various and complex. And the probe can not be fixed in each operation, so that the probe can touch the wall and bottom in the cell carrier, and the accuracy of the probe can be influenced.

Disclosure of Invention

Aiming at the defects of the prior art, the invention provides the multifunctional cell cryopreservation temperature probe fixing device, the design scheme has the advantages of reasonable structure, high reliability and easiness in use, and the problems that the conventional cell cryopreservation temperature probe fixing device needs to be recalibrated every time of replacement operation, wastes manpower and material resources, is repeatedly operated, and has various and complicated operation methods are solved.

The invention discloses a multifunctional cell cryopreservation temperature probe fixing device which comprises a bottom plate, a sample placing table, a cryopreservation placing frame and a hollow round rod, wherein the bottom plate is provided with a sample placing table; the sample placing table is positioned at the top of the bottom plate, the cryopreservation placing frame is positioned at the top of the bottom plate, and the hollow round rod is positioned at the top of the bottom plate; the hollow round rod is provided with a limiting rod, the outer wall of the hollow round rod is provided with a rotating handle, and the top of the limiting rod is fixedly connected with a fixing block; the freeze and deposit rack frame fixedly connected with on one's body rotates the knob, rotates the knob and keeps away from one side of freezing and deposit the rack and articulate there is the lid.

As a further improvement of the invention, a threaded hole is arranged on the rod body of the hollow round rod, a thread matched with the threaded hole is arranged at one end of the rotating handle, and the end of the rotating handle provided with the thread is in threaded connection with the threaded hole.

As a further improvement of the invention, the depression surface of the limiting rod is circular, the diameter of the depression surface of the limiting rod is smaller than the inner diameter of the depression surface of the hollow round rod, and the limiting rod is connected in the inner cavity of the hollow round rod in a sliding way.

As a further improvement of the invention, the fixing block comprises two square blocks which are opposite in an up-down mirror image mode, one sides of the two square blocks are rotatably connected together through hinges, a reserved hole is formed in one side, far away from the hinges, of the fixing block, two bolts are connected through threads of the fixing block, close to the reserved hole, and semicircular grooves are formed in the outer walls, close to one sides of the two square blocks, of the two square blocks.

As a further improvement of the invention, the sample placing table comprises a square plate and a round rod, the square plate is positioned at the top of the round rod, anti-skid grains are arranged on the sample placing table, and the sample placing table is positioned in the center between the fixed block and the cryopreservation placing frame and is close to the bottom of the fixed block.

As a further improvement of the invention, the freezing rack is positioned at the other end of the fixed block on the bottom plate, and the freezing rack is positioned on the same straight line with the middle points of the fixed block and the sample placing table.

As a further improvement of the invention, one side of the box cover close to the fixed block is provided with a preformed hole for inserting the probe, and two sides of the bottom of the box cover are fixedly connected with elastic elements.

As a further improvement of the invention, the bottom of the elastic element is fixedly connected with a thin pressing plate, the thin pressing plate is made of polycarbonate, and one side of the box cover is movably connected with a fixing clamp.

As a further improvement of the invention, the bottom plate, the hollow round rod, the fixing block, the sample placing table, the freezing and placing frame, the box cover, the rotating knob, the elastic element and the thin pressing plate are all connected in a welding mode.

As a further improvement of the invention, the bottom plate, the hollow round rod, the fixing block, the freezing storage rack, the sample placing table, the box cover, the elastic element, the fixing clamp, the limiting rod, the rotating handle and the rotating knob are all made of aluminum alloy.

Compared with the prior art, the invention has the following beneficial effects:

the invention can fix the height of the limiting rod in the hollow round rod by screwing and unscrewing the threaded hole on the hollow round rod and arranging the thread on one end of the rotating handle matched with the threaded hole on the hollow round rod, and then the probe can be flexibly controlled to the optimal monitoring height in the freezing storage tube by combining the centers of the upper and lower squares of the fixed block to form a circular groove through the reserved hole arranged at the front ends of the upper and lower squares of the fixed block and the hinge arranged at the rear ends of the upper and lower squares of the fixed block, thereby facilitating the placement of the fixed probe and preventing the probe from shaking, and simultaneously, through the position relation among the fixed block, the freezing storage rack and the sample placement platform, the probe can flexibly select the corresponding placement position according to a cell carrier and adjust the height of the limiting rod according to screwing and unscrewing the rotating handle, applicable different specifications such as 1.8ml, 4.5ml cryopreserved pipe to make this multi-functional cell cryopreserved temperature probe fixing device reach rational in infrastructure, safe and reliable's multi-functional cell cryopreserved temperature probe fixing device, can use a temperature probe to go to measure, monitor the temperature variation of different specifications cell carriers, convenient operation need not repeated calibration. The risk that the probe cannot be fixed and then the probe collides with the wall and touches the bottom in the cell carrier is eliminated, and the operation accuracy is improved.

Drawings

The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the application and together with the description serve to explain the application and not to limit the application. In the drawings:

FIG. 1 is a schematic perspective view of the present invention;

FIG. 2 is a schematic side view of the present invention;

FIG. 3 is a schematic view of the overall plan view configuration of the present invention;

fig. 4 is a schematic structural view of the front cross section of the cryopreservation rack of the present invention.

In the figure: 1. a base plate; 2. a hollow round bar; 3. rotating the handle; 4. a limiting rod; 5. a fixed block; 6. A sample placement stage; 7. freezing and storing the rack; 8. rotating the knob; 9. a box cover; 10. an elastic element; 11. A thin pressing plate; 12. and (4) fixing clips.

Detailed Description

In the following description, for purposes of explanation, numerous implementation details are set forth in order to provide a thorough understanding of the various embodiments of the present invention. It should be understood, however, that these implementation details are not to be interpreted as limiting the invention. That is, in some embodiments of the invention, such implementation details are not necessary. In addition, some conventional structures and components are shown in simplified schematic form in the drawings.

In addition, the descriptions related to the first, the second, etc. in the present invention are only used for description purposes, do not particularly refer to an order or sequence, and do not limit the present invention, but only distinguish components or operations described in the same technical terms, and are not understood to indicate or imply relative importance or implicitly indicate the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In addition, technical solutions between various embodiments may be combined with each other, but must be realized by a person skilled in the art, and when the technical solutions are contradictory or cannot be realized, such a combination should not be considered to exist, and is not within the protection scope of the present invention.

Example 1:

referring to fig. 1-4, a multifunctional cell cryopreservation temperature probe fixing device comprises a bottom plate 1, a sample placing table 6, a cryopreservation placing frame 7 and a hollow round rod 2; the sample placing table 6 is positioned at the top of the bottom plate 1, the freezing and placing frame 7 is positioned at the top of the bottom plate 1, and the hollow round rod 2 is positioned at the top of the bottom plate 1; a limiting rod 4 is arranged on the hollow round rod 2, a rotating handle 3 is arranged on the outer wall of the hollow cylinder 2, and a fixing block 5 is fixedly connected to the top of the limiting rod 4; the freezing rack 7 is fixedly connected with a rotating knob 8 on the body, and one side of the rotating knob 8 far away from the freezing rack 7 is hinged with a box cover 9.

In this embodiment, set up threaded hole on the pole body of hollow round bar 2, rotate one of handle 3 serve with screw hole assorted screw thread, and rotate handle 3 and establish threaded connection between screwed one end and the screw hole. The threaded end of the rotating handle 3 can be screwed and unscrewed through the threaded hole of the hollow round rod to fix the height of the limiting rod 4 arranged in the hollow round rod 2.

Both ends all are equipped with the preformed hole before two upper and lower squares of fixed block 5, and hinge connection is passed through at both ends behind two upper and lower squares of fixed block 5, and two upper and lower squares centers of fixed block 5 form circular recess after merging to place fixed probe. The probe is prevented from shaking.

Freeze and deposit rack 7 and lid 9 and articulate through rotating knob 8, and circular motion can be done to lid 9, and lid 9 is close to the probe direction and has the preformed hole, and the probe can pass the preformed hole, places the probe in the top after cell carrier is put into and freezes to deposit rack 7 on, closes lid 9 through fixation clamp 12.

The sample placing table 6 is placed between the fixed block 5 and the freezing storage rack 7 and is close to the lower side of the fixed block 5. The freezing rack 7 is arranged at the other end of the bottom plate 1 opposite to the fixed block 5. And the fixed block 5 freezes and deposits rack 7, and 6 mid points of sample platform are on a straight line. The probes can be fixed on the sample placing table 6 and the freezing and placing rack 7, and corresponding placing positions can be flexibly selected according to cell carriers.

Example 2:

on the basis of embodiment 1, be equipped with the screw hole on hollow round bar 2, gag lever post 4 is up-and-down reciprocating motion in hollow round bar 2, rotates handle 3 threaded one end and can screw through the screw hole of hollow round bar 2 and unscrew to place the height in hollow round bar 2 in fixed gag lever post 4.

In this embodiment, be equipped with the screw hole on hollow round bar 2, gag lever post 4 can be through reciprocating motion from top to bottom in hollow round bar 2, and rotate handle 3 threaded one end and screw the unscrewing through the screw hole on hollow round bar 2, with the position of fixing gag lever post 4 in hollow round bar 2, place the not co-altitude of platform 6 with fixed probe from the sample, thereby realize that the probe can insert the best degree of depth in the different cryopreserved pipes, reach the best precision of temperature monitoring and avoid the internal wall of colliding of cell carrier, the risk of touching the end.

Example 3:

on embodiment 2's basis, both ends all are equipped with the preformed hole before two upper and lower squares of fixed block 5, hinge connection is passed through at both ends behind two upper and lower squares of fixed block 5, two square centers form circular recess after merging about 5, in order to place fixed probe, the motion of opening and shutting is done to 5 accessible hinges of fixed block, it is fixed through bolted connection for the preformed hole at both ends in the front behind the probe to place, just do not receive external disturbance after the probe is fixed, avoid unexpected removal to lead to the probe to touch the wall, lead to the temperature deviation to appear of probe control.

In this embodiment, the probe is placed in the circular recess in 5 centers of fixed block, applicable in most temperature probe shapes on the market, convenient operation, circular motion realization is made through the hinge at both ends behind two upper and lower squares of fixed block 5 and is opened and shut, makes things convenient for taking out and fixing of probe, can also screw the nut on the preceding both ends bolt to two upper and lower squares of fixed block 5, thereby the elasticity of fixed probe, orientation etc..

Example 4:

on embodiment 3's basis, can place the cryopreserved pipe on the platform 6 is placed to the sample, has anti-skidding line can guarantee that cryopreserved box or cryopreserved pipe can not slide.

In this embodiment, adopt anti-skidding line, can increase frictional force, can prevent that the position of freezing storage box or standard sample from not receiving external force interference.

Example 5:

on the basis of embodiment 4, a preformed hole for inserting the probe is formed in one side of the box cover 9 close to the fixing block 5, elastic elements 10 are fixedly connected to two sides of the bottom of the box cover 9, a thin pressing plate 11 is fixedly connected to the bottom of the elastic elements 10, the thin pressing plate 11 is made of polycarbonate, and a fixing clamp 12 is movably connected to one side of the box cover 9.

In this embodiment, the lid 9 is closed, and the lid 9 is fixed with the cryopreserving rack 7 with fixation clamp 12, and thin clamp plate 11 is pressed the probe tightly on the cell carrier through elastic element 10 this moment, forms good heat conduction contact, and the temperature measurement is more accurate, and elastic element 10's free flexible can avoid the cell carrier volume expansion when freezing and is exploded the risk by the pressure again.

Example 6:

on the basis of embodiment 5, the bottom plate 1, the hollow round rod 2, the fixing block 5, the freezing and placing rack 7, the sample placing table 6, the box cover 9, the elastic element 10, the fixing clamp 12, the limiting rod 4, the rotating handle 3 and the rotating knob 8 are all made of aluminum-aluminum alloy. The thin platen 11 is polycarbonate.

In the embodiment, the components are made of aluminum alloy and polycarbonate, and have good heat conductivity, oxidation resistance and ductility in a low-temperature or deep-low-temperature operating environment.

In the use of the invention: when the cell carrier is for freezing when depositing the pipe, insert the probe and place the freezing of on the platform 6 with 5 below samples of fixed block and deposit the pipe after, accessible screw and loosen soon and rotate the height that 3 adjusted gag lever post 4 of handle, control the probe and freeze the intraductal best monitoring height that deposits, applicable 1.8ml, different specifications such as 4.5ml freeze and deposit the pipe.

When the cell carrier is a freezing bag, the freezing bag is placed above the freezing placing frame 7, the bolt on the fixing block 5 is unscrewed, the probe penetrates through a preformed hole in the box cover 9 and is placed above the freezing bag, the bolt on the fixing block 5 is screwed, and the box cover 9 is closed through the fixing clamp 12. The probe and the cryopreservation bag are tightly attached, and the monitoring is accurate.

The above description is only an embodiment of the present invention, and is not intended to limit the present invention. Various modifications and alterations to this invention will become apparent to those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the scope of the claims of the present invention.