Liquid nitrogen freezing type multi-sample biological tissue grinding device

文档序号:1961315 发布日期:2021-12-14 浏览:14次 中文

阅读说明:本技术 一种液氮冷冻型多样本生物组织研磨装置 (Liquid nitrogen freezing type multi-sample biological tissue grinding device ) 是由 连博琳 黄云鹏 张健 余春梅 刘世薇 于 2021-08-05 设计创作,主要内容包括:本发明公开了一种液氮冷冻型多样本生物组织研磨装置,包括底座和上盖,底座内设有研钵容纳槽,研钵容纳槽与底座壳体之间设有液氮腔室,研钵容纳槽内放置有研钵,研钵内分割成若干个研磨槽。上盖内设有电机,并在上盖底部设置若干研磨棒,当上盖与底座盖合时,每个研磨槽内均分布一根研磨棒,电机通过传动机构驱动研磨棒在研磨槽内转动来对生物组织进行研磨。本发明磨装置适用于对多样本进行自动化粗研磨,操作简便,研磨时不冻手、泼溅,省时省力又安全。本设备由于有封闭的腔室储存液氮因此能有效减少液氮消耗,同时只需按步骤安装好设备并倒入液氮就能开始工作。整个装置结构简单,制造成本相对较低。(The invention discloses a liquid nitrogen freezing type multi-sample biological tissue grinding device which comprises a base and an upper cover, wherein a mortar accommodating groove is formed in the base, a liquid nitrogen chamber is arranged between the mortar accommodating groove and a base shell, a mortar is placed in the mortar accommodating groove, and the mortar is divided into a plurality of grinding grooves. Be equipped with the motor in the upper cover to set up a plurality of grinding rods in the upper cover bottom, when the upper cover was fashionable with the base lid, every grinding inslot evenly distributes a grinding rod, and the motor passes through drive mechanism drive grinding rod and comes to grind biological tissue at the grinding inslot internal rotation. The grinding device is suitable for carrying out automatic rough grinding on multiple samples, is simple and convenient to operate, does not freeze hands or splash during grinding, and is time-saving, labor-saving and safe. The equipment can effectively reduce the consumption of liquid nitrogen because of the closed chamber for storing the liquid nitrogen, and simultaneously, the equipment can start to work only by installing the equipment according to steps and pouring the liquid nitrogen. The whole device has simple structure and relatively low manufacturing cost.)

1. The liquid nitrogen freezing type multi-sample biological tissue grinding device is characterized by comprising a base and an upper cover, wherein a mortar accommodating groove is formed in the base, a liquid nitrogen chamber is arranged between the mortar accommodating groove and a base shell, a mortar is placed in the mortar accommodating groove, and the mortar is divided into a plurality of grinding grooves; a motor is arranged in the upper cover, a plurality of grinding rods are arranged at the bottom of the upper cover, when the upper cover is covered with the base, one grinding rod is distributed in each grinding groove, and the motor drives the grinding rods to rotate in the grinding grooves through a transmission mechanism;

the transmission mechanism comprises a driving gear and driven gears, wherein the driving gear is positioned in the middle, the driven gears are uniformly distributed around the circumference of the driving gear, the driven gears are meshed with the driving gear, and the driving gear is driven by a motor to rotate; the grinding rod comprises a driving gear, a driven gear and a grinding rod, wherein the driving gear and the driven gears are fixedly connected with a square sleeve respectively, and a square prism at the top of the grinding rod can be fixedly connected with the square sleeve.

2. The liquid nitrogen freezing type multi-sample biological tissue grinding device according to claim 1, wherein the mortar accommodating groove is made of copper material and is wrapped with a rubber layer outside the base housing.

3. The liquid nitrogen freezing type multi-sample biological tissue grinding apparatus according to claim 1, wherein a set of grooves for facilitating taking out the mortar are oppositely provided at the top of the mortar accommodating groove.

4. The liquid nitrogen freezing type multi-sample biological tissue grinding device according to claim 1, wherein a liquid nitrogen inlet of the liquid nitrogen chamber is positioned at the top of the base, and a plug of the liquid nitrogen inlet is correspondingly arranged on the bottom surface of the upper cover.

5. The liquid nitrogen freezing type multi-sample biological tissue grinding device according to claim 1, wherein a touch pad is arranged on the top of the upper cover, and the touch pad is connected with a driving controller of the motor.

6. The liquid nitrogen freezing type multi-sample biological tissue grinding apparatus according to claim 1, wherein the upper portion of the grinding rod is smooth all around.

7. The liquid nitrogen freezing type multi-sample biological tissue grinding apparatus according to claim 1, wherein the mortar accommodating groove and the mortar side wall are waved.

Technical Field

The invention relates to a liquid nitrogen freezing type multi-sample biological tissue grinding device.

Background

In biological related scientific researches, the grinding of frozen samples is often needed, the traditional manual grinding is time-consuming and labor-consuming, liquid nitrogen is volatile at normal temperature, so that the liquid nitrogen is not fully used and is wasted, and the manual grinding of a large number of samples of different types is very laborious. The automatic cryogenic grinding machines available on the market are suitable for the case of small sample size, the equipment price is very expensive although the grinding is fine, and in addition, the steel balls used in the products have great trouble in cleaning.

Disclosure of Invention

The purpose of the invention is as follows: in view of the prior art, a liquid nitrogen freezing type multi-sample biological tissue grinding device is provided, which is suitable for roughly grinding large-amount frozen multi-samples.

The technical scheme is as follows: a liquid nitrogen freezing type multi-sample biological tissue grinding device comprises a base and an upper cover, wherein a mortar accommodating groove is formed in the base, a liquid nitrogen chamber is arranged between the mortar accommodating groove and a base shell, a mortar is placed in the mortar accommodating groove, and the mortar is divided into a plurality of grinding grooves; a motor is arranged in the upper cover, a plurality of grinding rods are arranged at the bottom of the upper cover, when the upper cover is covered with the base, one grinding rod is distributed in each grinding groove, and the motor drives the grinding rods to rotate in the grinding grooves through a transmission mechanism;

the transmission mechanism comprises a driving gear and driven gears, wherein the driving gear is positioned in the middle, the driven gears are uniformly distributed around the circumference of the driving gear, the driven gears are meshed with the driving gear, and the driving gear is driven by a motor to rotate; the grinding rod comprises a driving gear, a driven gear and a grinding rod, wherein the driving gear and the driven gears are fixedly connected with a square sleeve respectively, and a square prism at the top of the grinding rod can be fixedly connected with the square sleeve.

Further, the mortar accommodating groove is made of copper materials, and a rubber layer is wrapped outside the base shell.

Furthermore, a group of grooves which are convenient for taking out the mortar are oppositely arranged at the top of the mortar accommodating groove.

Furthermore, a liquid nitrogen inlet of the liquid nitrogen chamber is positioned at the top of the base, and a plug of the liquid nitrogen inlet is correspondingly arranged on the bottom surface of the upper cover.

Furthermore, a touch control plate is arranged at the top of the upper cover and connected with a driving controller of the motor.

Furthermore, the periphery of the upper part of the grinding rod is smooth.

Further, mortar holding tank and mortar lateral wall are the wave.

Has the advantages that: the liquid nitrogen freezing type multi-sample biological tissue grinding device is particularly suitable for automatic coarse grinding of multiple samples, is simple and convenient to operate, does not freeze hands or splash during grinding, and is time-saving, labor-saving and safe. The equipment can effectively reduce the consumption of liquid nitrogen because of the closed chamber for storing the liquid nitrogen, and simultaneously, the equipment can start to work only by installing the equipment according to steps and pouring the liquid nitrogen. The whole device has simple structure and relatively low manufacturing cost.

Drawings

FIG. 1 is a schematic top view of a base;

FIG. 2 is a cross-sectional view of the base;

FIG. 3 is a schematic top view of a mortar;

FIG. 4 is a schematic bottom view of the upper cover;

FIG. 5 is a schematic view of the transmission mechanism;

FIG. 6 is a schematic view of a polishing rod.

Detailed Description

The invention is further explained below with reference to the drawings.

As shown in fig. 1 and 2, the liquid nitrogen freezing type multi-sample biological tissue grinding device comprises a base and an upper cover, wherein a mortar accommodating groove 1 is arranged in the base, a liquid nitrogen chamber 3 is arranged between the mortar accommodating groove 1 and a base shell 2, a mortar is placed in the mortar accommodating groove 1, and the mortar is divided into a plurality of grinding grooves 4-1. The upper cover is internally provided with a motor, the bottom of the upper cover is provided with a plurality of grinding rods, when the upper cover is covered with the base, one grinding rod is distributed in each grinding groove 4-1, and the motor drives the grinding rods to rotate in the grinding grooves 4-1 through a transmission mechanism.

Wherein, mortar holding tank 1 and mortar are copper material, and mortar holding tank and mortar lateral wall are the wave, as shown in fig. 1, 3 to this area of contact of increase both, play better refrigeration effect. The rubber layer 5 is wrapped outside the base shell 2, and the effects of heat preservation and shock absorption are achieved. A set of grooves 6 which are convenient for taking out the mortar are oppositely arranged at the top of the mortar accommodating groove 1, so that the grinding is convenient for sampling and cleaning. A liquid nitrogen inlet 3-1 of the liquid nitrogen chamber 3 is positioned at the top of the base, a plug 7 of the liquid nitrogen inlet is correspondingly arranged on the bottom surface of the upper cover, and volatilization of liquid nitrogen in the liquid nitrogen chamber 3 can be slowed down after the plug 7 is covered.

As shown in FIG. 6, the top of the grinding rod is a square prism 8-1, the lower part is a cylinder, fine grinding threads 8-2 are arranged around the lower part of the cylinder, and smooth surfaces 8-3 are arranged around the upper part of the grinding rod and are used for preventing the ground tissues from climbing upwards along with the grinding threads 8-2, so that the biological tissues can be fully ground.

As shown in figures 4 and 5, the transmission mechanism comprises a driving gear 9-1 positioned in the middle and driven gears 9-2 uniformly distributed around the circumference of the driving gear 9-1, wherein the driven gears 9-2 are meshed with the driving gear 9-1, and the driving gear 9-1 is driven by a motor to rotate. The driving gear 9-1 and each driven gear 9-2 are respectively and fixedly connected with a square sleeve 9-3, and the square prism 8-1 at the top of the grinding rod can be tightly connected with the square sleeve 9-3. The top of the upper cover is provided with a touch pad which is connected with a driving controller of the motor. When a part of the grinding grooves 4-1 is selected for grinding, the grinding grooves 4-1 are symmetrically selected to keep the stress of the transmission mechanism uniform.

The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

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