Cache disk module, operation method of cache disk module and sample analyzer

文档序号:1963002 发布日期:2021-12-14 浏览:15次 中文

阅读说明:本技术 缓存盘模块、缓存盘模块的运转方法及样本分析仪 (Cache disk module, operation method of cache disk module and sample analyzer ) 是由 曾钧生 罗岚 于 2021-09-17 设计创作,主要内容包括:本发明提供一种缓存盘模块、缓存盘模块的运转方法及样本分析仪。属于检测设备领域。缓存盘模块上设置有工作位,所述工作位中至少一个为混匀位,所述混匀位上对应设置有混匀装置,所述混匀装置用于混匀反应容器中的内容物。缓存盘模块的运转方法,提供如上的缓存盘模块,包括如下步骤:驱动转动盘按次转动,转动盘单次转动的角度为360k/n;样本分析仪,包括吸取针模块,孵育盘模块、试剂盘模块、检测器模块及如上的缓存盘模块。本发明能够在缓存盘模块中对反应容器中的内容物进行混合,减少了后续的反应时间,提高检测效率。无需再设置输送机构,简化了分析仪的结构,减少了分析仪的体积及生产成本。(The invention provides a cache disk module, an operation method of the cache disk module and a sample analyzer. Belongs to the field of detection equipment. The buffer memory disc module is provided with working positions, at least one of the working positions is a mixing position, a mixing device is correspondingly arranged on the mixing position, and the mixing device is used for mixing contents in the reaction container. The operation method of the cache disk module provides the cache disk module, and comprises the following steps: the rotating disc is driven to rotate for multiple times, and the single rotation angle of the rotating disc is 360 k/n; the sample analyzer comprises a suction needle module, an incubation disc module, a reagent disc module, a detector module and the cache disc module. The invention can mix the content in the reaction vessel in the cache disk module, thereby reducing the subsequent reaction time and improving the detection efficiency. And a conveying mechanism is not required to be arranged, so that the structure of the analyzer is simplified, and the volume and the production cost of the analyzer are reduced.)

1. A cache disk module, comprising: the buffer memory disc module is provided with a working position, at least one of the working positions is a mixing position, a mixing device is correspondingly arranged on the mixing position, and the mixing device is used for mixing contents in the reaction container.

2. The cache disk module of claim 1, wherein the blending device comprises:

the oscillating assembly is used for oscillating the reaction vessel and uniformly mixing the contents in the reaction vessel;

the cup blocking component and the oscillating component form an oscillating position for placing the reaction vessel;

and the driving assembly is used for driving the oscillating assembly and the cup blocking assembly to move oppositely, so that the reaction container is clamped between the cup blocking assembly and the oscillating assembly.

3. The cache disk module of claim 2, wherein: the cup blocking component comprises a fixing part and a top pressing part, and the connecting line direction between the cup blocking component and the oscillating component is a pressing direction;

in the compressing direction, one end of the compressing top is used for compressing the reaction vessel, the other end of the compressing top is movably connected to the fixing part, and the fixing part is fixedly arranged and used for constraining the position of the compressing top in the compressing direction.

4. The cache disk module of claim 3, wherein: the top pressing part is used for pressing one end of the reaction vessel tightly, the shape of the top is matched with the opening of the reaction vessel, and when the oscillating assembly and the cup blocking assembly clamp the reaction vessel tightly, the top is pressed on the opening of the reaction vessel tightly.

5. The cache disk module of claim 3, wherein: the cup pressing top is provided with a cup blocking rod, the fixing part is provided with a cup blocking seat, and the cup blocking rod is arranged along the pressing direction; a moving groove is formed in the cup blocking seat, one end of the cup blocking rod penetrates through the moving groove, a cup blocking screw is arranged at one end of the cup blocking rod, which penetrates through the moving groove, and the position of the cup blocking rod in the pressing direction is restrained by the cup blocking screw; and a spring is arranged on the cup blocking rod along the compression direction and is used for pressing the cup blocking rod on the reaction container.

6. The cache disk module of claim 4, wherein: one side of the top head, which is matched with the opening of the reaction container, is a plane; or one side of the top matched with the opening of the reaction container is a revolution surface, the revolution axis of the revolution surface is arranged along the pressing direction, the bus of the revolution surface is a fairing curve, and the bus is gradually close to the revolution axis in the direction towards the reaction container.

7. The cache disk module according to any one of claims 2 to 6, wherein: the oscillating module includes an oscillating portion that rotates when the oscillating module oscillates the reaction vessel, and an axis of rotation of the oscillating portion is deviated from a center of mass of the reaction vessel to oscillate the reaction vessel.

8. The cache disk module of claim 7, wherein: the reaction container detection device is characterized in that an embedding hole used for containing the reaction container is formed in the oscillating portion, the embedding hole is formed in the direction of the rotating axis of the oscillating portion, a detection area used for detection is arranged between the opening and the bottom of the reaction container, when the reaction container is placed in the embedding hole, the detection area enters the embedding hole, the opening of the reaction container leaks out of the embedding hole, and the axis of the embedding hole and the rotating axis of the oscillating portion are eccentrically arranged.

9. The cache disk module of claim 7, wherein: the oscillating assembly further comprises a power part, and the power part is used for driving the oscillating part to rotate.

10. The cache disk module according to any one of claims 2 to 6 or 8 to 9, wherein: the driving assembly comprises a driving portion and a moving portion, the oscillating assembly is arranged on the moving portion, and the oscillating assembly is close to or far away from the cup retaining assembly along the clamping direction along with the moving portion.

11. The cache disk module of claim 10, wherein: the one end that the motion trail of motion portion is close to the glass blocking subassembly is the clamping position, the one end that the motion trail of motion portion kept away from the glass blocking subassembly is the initiating position, be provided with on the initiating position and be used for detecting the detector that resets of motion portion position.

12. The cache disk module of claim 10, wherein: the driving part comprises a driving motor, a driving belt pulley, a driven belt pulley and a linear guide rail arranged along the compressing direction, the moving part comprises a sliding block, the oscillating assembly is arranged on the linear guide rail through the sliding block, a synchronous belt is arranged between the driving belt pulley and the driven belt pulley and is connected with the sliding block, the driving motor drives the driving belt pulley to rotate, and the driving belt pulley drives the oscillating assembly to slide on the linear guide rail along with the sliding block through the synchronous belt; or, the driving part is a cam mechanism; or the driving part is a gear rack mechanism; alternatively, the driving part is a link mechanism.

13. The cache disk module according to any one of claims 1 to 6, 8 to 9, or 11 to 12, wherein: the utility model discloses a reaction vessel, including the position of working, the position of working is two at least, the buffer memory dish module is still including being used for the storage reaction vessel and drive reaction vessel is in the buffer memory device that moves between the position of working, buffer memory device includes the rolling disc, wind on the rolling disc the axis of rotation of rolling disc is provided with and is used for placing reaction vessel's screens, the position of working corresponds the setting respectively on the rotation track of screens, the rolling disc drive reaction vessel in the screens is in move between the position of working.

14. The cache disk module of claim 13, wherein: the screens is for setting up be used for placing on the rolling disc reaction vessel's through-hole, reaction vessel can rock in the through-hole.

15. The cache disk module of claim 13, wherein: the working position also comprises a sample adding position for adding samples into the reaction container; the working position further comprises a disc feeding position, the reaction container enters the disc feeding position in a clamping position of the rotating disc, the sample adding position and the mixing position are sequentially arranged in the rotating direction of the rotating disc, and the disc feeding position is arranged in front of the sample adding position.

16. The cache disk module of claim 15, wherein: the feeding position and the sample adding position are provided with a first detection unit for detecting the condition of the reaction container in the clamping position, and the sample adding position is also provided with a second detection unit for detecting the condition of the reaction container in the sample adding position.

17. The cache disk module of claim 14, wherein: the working position further comprises a grabbing position, the grabbing position is arranged behind the mixing position in the rotating direction of the rotating disc, and the reaction container is arranged on the grabbing position and is separated from the rotating disc along the hole of the clamping position.

18. The cache disk module of claim 17, wherein: the buffer device further comprises a block-up block, the block-up block corresponds to the grabbing position, the block-up block is arranged on the rotating track of the clamping position, the block-up block faces towards the clamping position and protrudes out, and the block-up block is used for driving a reaction container in the clamping position to move along the hole direction of the clamping position.

19. The cache disk module of claim 13, wherein: the buffer device also comprises a surrounding baffle, the surrounding baffle is arranged around the edge of the rotating disc, the rotating disc rotates in the surrounding baffle, the edge of the rotating disc is provided with a disc inlet opening communicated with the clamping position, and the surrounding baffle is matched with the edge of the rotating disc to restrain the reaction container in the clamping position;

the enclosing baffle is also provided with a filling opening, and the reaction container enters the clamping position through the filling opening and the tray inlet opening.

20. The cache disk module according to any one of claims 14 to 19, wherein: the screens is a plurality of, the quantity of screens is greater than or equal to the quantity of work position, and is a plurality of the screens with the axis of rotation of rolling disc is the centre of a circle, sets up on same circle.

21. The cache disk module of claim 20, wherein: a plurality of screens evenly distributed in on the rolling disc.

22. A method for operating a cache disk module, wherein the cache disk module according to claim 21 is provided, the work stations are respectively arranged corresponding to one of a plurality of the screens, and the number of the screens is n;

the operation method comprises the following steps:

driving the rotating disc to rotate for multiple times, wherein the single rotation angle of the rotating disc is 360 k/n;

wherein the content of the first and second substances,

k is equal to 1, or

k is a positive integer other than 1, and the remainder of n/k is 1.

23. A sample analyzer, comprising: comprises a suction needle module, an incubation disk module, a reagent disk module, a detector module and a cache disk module as claimed in any one of claims 1-23,

wherein the content of the first and second substances,

the suction needle module is used for sucking a reagent or a sample and placing the reagent or the sample into a reaction container to be detected;

a reagent disk module for storing reagents;

the incubation disc module is used for incubating the object to be detected to meet the condition required by the reaction of the reagent and the sample;

and the detector module is used for detecting the object to be detected to obtain a detection result.

Technical Field

The invention belongs to the field of detection equipment, and particularly relates to a cache disk module, an operation method of the cache disk module and a sample analyzer.

Background

The buffer disk module is an important component in the detection instrument and is used for buffering the reaction container of the detection instrument so as to adjust the transfer section of the reaction container, and the conveying speed of the reaction container meets the subsequent rhythm requirement of the detection instrument.

The current cache disk module only plays a role in responding to rhythm of container transportation, and has the advantages of single function, small size, less cache quantity, short running period of the cache disk and incapability of helping the whole working flow of an instrument. In addition, most of the common blending components need to be arranged independently, and a component for transferring a reaction container needs to be arranged in a detection instrument and is matched with the blending components to complete the blending function. Which increases the volume of the detection instrument.

Disclosure of Invention

In view of the above-mentioned shortcomings of the prior art, an object of the present invention is to provide a buffer disk module, a method for operating the buffer disk module, and a sample analyzer, which are used to solve the problem of complex structure of the detection instrument in the prior art.

In order to achieve the above and other related objects, the present invention provides a cache disk module, wherein the cache disk module is provided with work stations, at least one of the work stations is a blending station, and the blending station is correspondingly provided with a blending device for blending contents in a reaction vessel.

Optionally, the blending device includes: the oscillating assembly is used for oscillating the reaction vessel and uniformly mixing the contents in the reaction vessel; the cup blocking component and the oscillating component form an oscillating position for placing the reaction vessel; and the driving assembly is used for driving the oscillating assembly and the cup blocking assembly to move oppositely, so that the reaction container is clamped between the cup blocking assembly and the oscillating assembly.

Optionally, the cup blocking assembly comprises a fixing portion and a top pressing portion, and a connecting line direction between the cup blocking assembly and the oscillating assembly is a pressing direction; in the compressing direction, one end of the compressing top is used for compressing the reaction vessel, the other end of the compressing top is movably connected to the fixing part, and the fixing part is fixedly arranged and used for constraining the position of the compressing top in the compressing direction.

Optionally, one end of the capping portion, which is used for being pressed against the reaction vessel, is a plug, the shape of the plug is matched with the opening of the reaction vessel, and when the oscillating assembly and the cup blocking assembly clamp the reaction vessel, the plug is pressed against the opening of the reaction vessel.

Optionally, the cup pressing top is a cup blocking rod, the fixing part is a cup blocking seat, and the cup blocking rod is arranged along the pressing direction; a moving groove is formed in the cup blocking seat, one end of the cup blocking rod penetrates through the moving groove, a cup blocking screw is arranged at one end of the cup blocking rod, which penetrates through the moving groove, and the position of the cup blocking rod in the pressing direction is restrained by the cup blocking screw; and a spring is arranged on the cup blocking rod along the compression direction and is used for pressing the cup blocking rod on the reaction container.

Optionally, one side of the plug, which is matched with the opening of the reaction container, is a plane; or one side of the top matched with the opening of the reaction container is a revolution surface, the revolution axis of the revolution surface is arranged along the pressing direction, the bus of the revolution surface is a fairing curve, and the bus is gradually close to the revolution axis in the direction towards the reaction container.

Optionally, the oscillation assembly includes an oscillation part that rotates when the oscillation assembly oscillates the reaction vessel, and an axis of rotation of the oscillation part is offset from a center of mass of the reaction vessel to oscillate the reaction vessel.

Optionally, an insertion hole for accommodating the reaction container is formed in the oscillating portion, the insertion hole is formed along the direction of the rotation axis of the oscillating portion, a detection region for detection is arranged between the opening and the bottom of the reaction container, when the reaction container is placed in the insertion hole, the detection region enters the insertion hole, the opening of the reaction container leaks out of the insertion hole, and the axis of the insertion hole and the rotation axis of the oscillating portion are eccentrically arranged.

Optionally, a guide surface for guiding the reaction vessel when the reaction vessel enters the insertion hole is arranged on the opening of the insertion hole.

Optionally, the oscillating assembly further comprises a power part for driving the oscillating part to rotate.

Optionally, the driving assembly includes a driving portion and a moving portion, the oscillating assembly is disposed on the moving portion, and the oscillating assembly moves together with the moving portion in the clamping direction toward or away from the cup assembly.

Optionally, one end of the motion track of the motion portion, which is close to the cup blocking assembly, is a clamping position, one end of the motion track of the motion portion, which is far away from the cup blocking assembly, is a start position, and a reset detector for detecting the position of the motion portion is arranged on the start position.

Optionally, the driving portion includes a driving motor, a driving pulley, a driven pulley, and a linear guide rail arranged along the compressing direction, the moving portion includes a slider, the oscillating assembly is arranged on the linear guide rail through the slider, a synchronous belt is arranged between the driving pulley and the driven pulley, the synchronous belt is connected to the slider, the driving motor drives the driving pulley to rotate, the driving pulley drives the oscillating assembly to slide on the linear guide rail together with the slider through the synchronous belt, or the driving portion is a cam mechanism; or the driving part is a gear rack mechanism; alternatively, the driving part is a link mechanism.

Optionally, the work position is two at least, the buffer memory dish module still includes and is used for the storage reaction vessel and drive reaction vessel is in the buffer memory device that moves between the work position, buffer memory device includes the rolling disc, wind on the rolling disc the axis of rotation of rolling disc is provided with and is used for placing reaction vessel's screens, the work position corresponds the setting respectively on the rotation track of screens, the rolling disc drive reaction vessel in the screens is in move between the work position.

Optionally, the screens are through holes arranged on the rotating disc and used for placing the reaction vessels, and the reaction vessels can rock in the through holes.

Optionally, the work site further comprises a sample application site for applying a sample to the reaction vessel; the working position further comprises a disc feeding position, the reaction container enters the disc feeding position in a clamping position of the rotating disc, the sample adding position and the mixing position are sequentially arranged in the rotating direction of the rotating disc, and the disc feeding position is arranged in front of the sample adding position.

Optionally, a first detection unit for detecting the condition of the reaction container in the clamping position is arranged between the tray feeding position and the sample adding position, and a second detection unit for detecting the condition of the reaction container in the sample adding position is further arranged on the sample adding position.

Optionally, the work position still includes grabs the position, in the direction of rotation of rolling disc, it sets up to grab the position mix after the position, reaction vessel is in it follows to grab the position the hole of screens breaks away from the rolling disc.

Optionally, buffer memory device still includes the bed hedgehopping piece, the bed hedgehopping piece correspond grab the position setting, the bed hedgehopping piece sets up on the rotation orbit of screens, the bed hedgehopping piece orientation the screens is protruding, is used for driving reaction vessel in the screens is followed the hole of screens is to the motion.

Optionally, the buffer device further includes a surrounding barrier, the surrounding barrier is disposed around the edge of the rotating disk, the rotating disk rotates in the surrounding barrier, a disk entrance opening communicated with the clamping position is formed in the edge of the rotating disk, and the surrounding barrier is matched with the edge of the rotating disk to restrain the reaction container in the clamping position;

the enclosing baffle is also provided with a filling opening, and the reaction container enters the clamping position through the filling opening and the tray inlet opening.

Optionally, the screens are a plurality of, the quantity of screens is greater than or equal to the quantity of work position, it is a plurality of the screens use the axis of rotation of rolling disc is the centre of a circle, sets up on same circle.

Optionally, a plurality of the detents are evenly distributed on the rotating disc.

The invention also provides an operation method of the cache disk module, which comprises the steps of providing the cache disk module, wherein the working positions are respectively arranged corresponding to one of the clamping positions, and the number of the clamping positions is n;

the method comprises the following steps: driving the rotating disc to rotate for multiple times, wherein the single rotation angle of the rotating disc is 360 k/n;

wherein k is equal to 1, or k is a positive integer except 1 and the remainder of n/k is 1.

The invention also provides a sample analyzer, which comprises a suction needle module, an incubation disc module, a reagent disc module, a detector module and the cache disc module, wherein the suction needle module is used for sucking a reagent or a sample and placing the reagent or the sample into a reaction container to be detected; a reagent disk module for storing reagents; the incubation disc module is used for incubating the object to be detected to meet the condition required by the reaction of the reagent and the sample; and the detector module is used for detecting the object to be detected to obtain a detection result.

As described above, the cache disk module, the method for operating the cache disk module, and the sample analyzer according to the present invention have the following advantageous effects:

because the cache disk module comprises a content blending device for blending the contents in the reaction vessel, the blending device can blend the contents in the reaction vessel in the cache disk module. After the contents in the reaction container are mixed, the contents can react while being cached, so that the subsequent reaction time is reduced, the total detection time is shortened, and the detection efficiency is improved. Compared with a mixing device which is arranged independently, the buffer disk module comprises the mixing device, so that a conveying mechanism is not required to be arranged between the buffer disk module and the mixing device, the detection steps are simplified, the detection efficiency is improved, the structure of the analyzer is greatly simplified, and the volume and the production cost of the analyzer are reduced.

Drawings

Fig. 1 is a schematic perspective view of a cache disk module according to an embodiment of the present invention;

FIG. 2 is a schematic structural diagram of a fence and a cache disk body according to an embodiment of the invention.

Fig. 3 is a schematic cross-sectional view of a cache disk module according to an embodiment of the invention.

Fig. 4 is a schematic structural diagram of a baffle plate assembly in an embodiment of the invention.

Fig. 5 is a schematic structural diagram of a fixing base according to an embodiment of the invention.

Fig. 6 is a schematic structural diagram of an oscillating device and a driving device according to an embodiment of the invention.

Fig. 7 is a schematic structural view of a top cup rod in an embodiment of the invention.

FIG. 8 is a schematic cross-sectional view of a blending apparatus and a buffer apparatus according to an embodiment of the present invention.

Fig. 9 is a schematic diagram illustrating an operation of a cache module according to an embodiment of the invention.

FIG. 10 is a schematic view of a structure of a locking and tray-entering opening according to an embodiment of the present invention.

Description of reference numerals: the buffer memory disk module 1, the reaction vessel 2, the cup blocking component 3, the cleaning component 4, the support column 5, the driving component 6, the wiring terminal adapter plate 7, the filling opening 8, the rotating bearing 9, the enclosure 10, the round hole 11, the rotating disk 12, the cup blocking rod 13, the cup blocking seat 14, the buffer memory disk body 15, the driving pulley 16, the driving motor 17, the detection optical coupler 18, the driven pulley 19, the synchronous belt 20, the oscillating motor 21, the rotating motor 22, the top 23, the cup blocking screw 24, the spring 25, the moving groove 26, the oscillating component 27, the cup blocking rod 28, the linear guide rail 29, the lifting plate 30, the tensioning piece 31, the tensioning screw 32, the reset optical coupler 33, the blocking piece 34, the connecting piece 35, the sliding block 36, the fixing piece 37, the embedding hole 38, the tool debugging hole 39, the clamping debugging hole 40, the connecting hole 41, the buffer memory disk bottom plate 42, the connecting shaft 43, the code disk 44 and the position detection optical coupler 45. The device comprises a tray feeding position 46, a detection position 47, a sample adding position 48, a blending position 49, a grabbing position 50, a blending device 51, a caching device 52, a tray feeding opening 53 and a clamping position 54.

Detailed Description

The embodiments of the present invention are described below with reference to specific embodiments, and other advantages and effects of the present invention will be easily understood by those skilled in the art from the disclosure of the present specification. The invention is capable of other and different embodiments and of being practiced or of being carried out in various ways, and its several details are capable of modification in various respects, all without departing from the spirit and scope of the present invention.

Please refer to fig. 1 to 10. It should be noted that the drawings provided in the present embodiment are only for illustrating the basic idea of the present invention, and the components related to the present invention are only shown in the drawings rather than drawn according to the number, shape and size of the components in actual implementation, and the type, quantity and proportion of the components in actual implementation may be changed freely, and the layout of the components may be more complicated. The structures, proportions, sizes, and other dimensions shown in the drawings and described in the specification are for understanding and reading the present disclosure, and are not intended to limit the scope of the present disclosure, which is defined in the claims, and are not essential to the art, and any structural modifications, changes in proportions, or adjustments in size, which do not affect the efficacy and attainment of the same are intended to fall within the scope of the present disclosure. In addition, the terms "upper", "lower", "left", "right", "middle" and "one" used in the present specification are for clarity of description, and are not intended to limit the scope of the present invention, and the relative relationship between the terms and the terms is not to be construed as a scope of the present invention.

Most of the existing blending devices achieve blending action on reactants through blending holes with irregular shapes, blending objects are generally square reaction cups, other limiting structures are not arranged above the blending process, and if the rotating speed of a blending driving motor is too high, the reactants overflow or even the reaction cups fly off.

Referring to fig. 1, the present embodiment provides a cache disk module 1, where the cache disk module 1 includes a work station for processing a reaction container 2, and in the present embodiment, the reaction container 2 is a cylindrical reaction cup. The working position at least comprises a blending position, a blending device 51 is correspondingly arranged on the blending position, and the blending device 51 is used for blending the contents in the reaction vessel. The buffer disk module 1 further comprises a buffer device 52, and the buffer device 52 is used for storing the reaction containers 2 and driving the reaction containers 2 to move between the working positions. The cache disk module 1 comprises a wiring terminal adapter plate 7 and a support column 5, wherein the wiring terminal adapter plate 7 is used for connecting various cables, and the support column 5 supports the cache disk module 1.

As shown in fig. 3 and 6, the blending device 51 of the present embodiment includes an oscillating assembly 27, a cup blocking assembly 3, and a driving assembly 6. An oscillation position for placing the reaction vessel 2 is formed between the cup retaining component 3 and the oscillation component 27, and when the reaction vessel 2 is placed on the oscillation position, the oscillation component 27 can oscillate the reaction vessel 2 and uniformly mix the content in the reaction vessel 2. The driving assembly 6 is used for driving the oscillating assembly 27 and the cup blocking assembly 3 to move towards each other, so that the reaction vessel 2 placed on the oscillating position is clamped between the cup blocking assembly 3 and the oscillating assembly 27.

In the process of oscillating the reaction vessel 2 by the oscillating assembly 27, the reaction vessel 2 is clamped tightly, and the cup blocking assembly 3 is matched with the oscillating assembly 27 to well limit the reaction vessel 2, so that the reaction vessel 2 is prevented from falling off in the oscillating process.

As shown in fig. 4, the cup blocking member 3 includes a fixing portion and a pressing portion, and a connection direction between the cup blocking member 3 and the oscillating member 27 is a pressing direction. In the pressing direction, one end of the pressing top part is used for pressing the reaction vessel 2, and the other end of the pressing top part is movably connected to the fixed part.

The fixing part is fixedly arranged and used for restraining the position of the coping part in the pressing direction and limiting the movement of the coping part in the direction deviating from the oscillating assembly 27. The fixing portion is fixedly arranged, so that when the reaction vessel 2 is clamped, the fixing portion can provide support for the whole cup retaining assembly 3 and provide necessary reaction force for clamping the reaction vessel 2. Meanwhile, the top pressing part is movably connected to the fixing part, so that when the top pressing part is tightly pressed on the reaction container 2 by the fixing part, the top pressing part can still move regularly in a small range up and down relative to the fixing part, and flexible connection between the top pressing part and the fixing part is achieved. When the oscillating assembly 27 oscillates the reaction vessel 2, the pressing top can move correspondingly, and the attenuation and the interference to the oscillation are eliminated.

In order to secure the oscillation effect of the content in the reaction vessel 2, the oscillation amplitude of the reaction vessel 2 is generally large, and therefore the content is easily splashed out of the opening of the reaction vessel 2. In this embodiment, one end of the pressing top for pressing against the reaction vessel 2 is a head 23, the shape of the head 23 matches with the opening of the reaction vessel 2, and when the oscillating assembly 27 and the cup holder assembly 3 clamp the reaction vessel 2, the head 23 presses against the opening of the reaction vessel 2. When the reaction vessel oscillates, the top head 23 presses the reaction vessel 2, so that the reaction vessel is not separated, and the contents in the reaction vessel 2 are stably and uniformly mixed.

In this embodiment, the cup pressing portion is a cup blocking rod 13, the fixing portion is a cup blocking base 14, and the cup blocking rod 13 is arranged along the pressing direction. The plug 23 is arranged at one end of the cup blocking rod 13, and the other end of the cup blocking rod 13 is connected to the cup blocking seat 14. As shown in fig. 5, a moving groove 26 is formed in the cup blocking base 14, and an end of the cup blocking rod 13 away from the moving-end plug 23 penetrates through the moving groove 26. The size of the cup bar 13 is smaller than that of the moving groove 26, so that the cup bar 13 can be shaken in the moving groove 26. Meanwhile, one end of the cup blocking rod 13, which penetrates through the moving groove 26, is provided with a cup blocking screw 24, the size of the cup blocking screw 24 is larger than that of the moving groove 26, and the cup blocking screw 24 restrains the cup blocking rod 13 in the pressing direction. Since the cup stopper screw 24 restrains the cup stopper rod 13 to the cup stopper 14, the cup stopper rod 13 does not come out of the moving groove 26 toward the oscillating assembly 27 when there is no reaction vessel 2 between the cup stopper rod and the oscillating assembly 27.

A spring 25 is arranged between the cup blocking seat 14 and the plug 23 along the pressing direction, and the cup blocking seat 14 limits the plug 23 through the spring 25. When the driving assembly 6 drives the oscillating assembly 27 to move towards the baffle seat, the baffle seat is fixed, the reaction vessel 2 continues to move after being attached to the top head 23, and the spring 25 is compressed. The spring 25, when compressed, acts against the ram 23 to compress the ram 23 against the reaction vessel 2, clamping the reaction vessel 2 between the oscillation assembly 27 and the baffle assembly. The spring 25 can provide a pressing force within the extension range. The requirement on the position degree of the reaction container 2 during clamping can be reduced, the reaction container 2 is prevented from being damaged by pressure during clamping, and the production difficulty and the process requirement of equipment are reduced.

In this embodiment, the moving slot 26 is rectangular. The cup retaining base 14 is a stressed component, and four corners of the rectangle are respectively rounded, so that stress concentration of the moving groove 26 can be reduced, and the moving groove 26 is prevented from cracking.

The edges of the openings of the reaction vessels 2 are in the same plane, so that the side of the plug 23 matching the openings of the reaction vessels 2 can be a plane to match and block the openings of the reaction vessels 2. The plane processing is simple, and the production and the processing of equipment are easy. When the opening of the reaction vessel 2 is circular, the side of the plug 23 matching the opening of the reaction vessel 2 is a surface of revolution, and the axis of revolution of the surface of revolution is arranged along the direction of compression. The generatrix of the surface of revolution is a smooth curve, and in the direction towards the reaction vessel 2, the generatrix of the surface of revolution is gradually close to the axis of revolution. When the opening of the reaction container 2 needs to be plugged, the revolution surface moves towards the inside of the opening until the revolution surface is attached to the opening. Because the generating line of surface of revolution is the smooth curve and is close to the axis of revolution gradually in the direction towards reaction vessel 2, surface of revolution is smooth gradual change from big to little in the direction towards reaction vessel 2, therefore surface of revolution can adapt to the opening of different specification reaction vessels 2, and application range is wide. Meanwhile, the revolution surface has a guiding function in the process of entering the opening of the reaction vessel 2, the centering requirement between the revolution surface and the opening of the reaction vessel 2 is reduced, and the production difficulty of equipment is reduced.

As shown in fig. 8, the oscillating module 27 includes an oscillating portion for connection with the reaction vessel 2, a rotation axis of the oscillating portion being disposed in the pressing direction, and a center of mass of the reaction vessel 2 and the rotation axis of the oscillating portion being eccentrically disposed when the oscillating portion acts on the reaction vessel 2. When it is necessary to mix the contents in the reaction vessel 2, the oscillating portion is rotated. In the rotating process of the oscillating part, because the mass center of the reaction vessel 2 is not arranged on the rotating axis of the oscillating part, the reaction vessel 2 is subjected to the acting force which changes the direction periodically, so that the reaction vessel 2 oscillates, and the content in the reaction vessel 2 is uniformly mixed.

A detection area for detecting the reaction effect is arranged between the opening and the bottom of the reaction container 2, and the surface smoothness of the detection area is high in order not to influence the detection effect. Specifically, in the present embodiment, the oscillating portion is provided with an insertion hole 38, and the insertion hole 38 is used for accommodating the reaction container 2. When the reaction vessel 2 is placed in the insertion hole 38, the detection region is contained in the insertion hole 38, and the opening of the reaction vessel 2 leaks out of the insertion hole 38. The insertion hole 38 protects the detection region on the reaction container 2 during oscillation of the reaction container 2, and prevents scratches on the detection region.

The axis of the embedding hole 38 and the rotation axis of the oscillating part are eccentrically arranged, so that after the reaction container 2 is placed into the embedding hole 38, the mass center of the reaction container 2 deviates from the rotation axis of the oscillating part, and the effect of oscillation and uniform mixing is achieved.

As shown in fig. 7, the oscillating portion in this embodiment is a top cup bar 28, the top cup bar 28 is disposed in the pressing direction, and an insertion hole 38 is provided on one end of the top cup bar 28. The other end of the cup ejecting rod 28 is provided with a clamping and debugging hole 40 and a connecting hole 41, and the clamping and debugging hole 40 and the connecting hole 41 are used for debugging the position of the oscillating assembly 27, so that the center positions of the oscillating assembly 27, the cup blocking assembly 3 and the mixing position are on the same central axis.

The cup-supporting rod 28 is rod-shaped, so that the volume of the oscillating part is reduced while the oscillating effect is ensured. The insertion hole 38 is provided with a guide surface at its opening. The guide surface can guide the reaction vessel 2 when the reaction vessel 2 enters the insertion hole 38, and the reaction vessel 2 can easily enter the insertion hole 38 when the knock-up pin 28 moves toward the reaction vessel 2. In this embodiment, the oscillating module 27 further includes a power unit, which provides power to the oscillating unit to drive the oscillating unit to rotate when the oscillating unit oscillates the reaction vessel 2. In this embodiment, the power part is the oscillating motor 21, and the rotational speed and the moment of torsion of the oscillating motor 21 are easily adjusted, operate steadily, and the noise is little, is suitable for the laboratory environment to use.

The bottom of the insertion hole 38 is provided with a tool debugging hole 39, the tool debugging hole 39 is smaller than the insertion hole 38, the tool debugging hole 39 is arranged along the direction of the rotation axis of the oscillating portion, and the tool debugging hole 39 and the ejection cup rod 28 are coaxial. The tool debugging hole 39 is used for positioning the cup ejecting rod 28 during the assembly of the oscillating part, and ensures that the rotation axis of the cup ejecting rod 28 is coaxial with the axis of the clamping position 54 on the blending position.

In this embodiment, the driving assembly 6 includes a driving portion and a moving portion, the oscillating assembly 27 is disposed on the moving portion, and the oscillating assembly 27 moves together with the moving portion in the clamping direction toward or away from the cup assembly 3. One end of the motion track of the motion part, which is close to the cup blocking component 3, is a clamping position, one end of the motion track of the motion part, which is far away from the cup blocking component 3, is a starting position, and a reset detector is arranged on the starting position. The reset detector is used for detecting the position of the motion part, can detect the reset condition of the motion part and prevents other reaction vessels 2 from moving to the oscillation position to cause instrument damage under the condition that the motion part is not reset. In this embodiment, the position detector is a reset optical coupler 33, a blocking piece 34 used in cooperation with the reset optical coupler 33 is arranged on the moving portion, and the reset optical coupler 33 detects the position of the moving portion through the blocking piece 34. The blocking piece 34 moves between the clamping position and the starting position along with the moving part, when the moving part leaves the starting position, the blocking piece 34 leaves the detection range of the reset optical coupler 33, and when the moving part returns to the starting position, the blocking piece 34 enters the detection range of the reset optical coupler 33.

In some embodiments, the driving portion may be a cam mechanism, a rack and pinion mechanism, a linkage mechanism, or the like, for achieving the movement of the oscillating assembly 27 between the clamping position and the start position. In this embodiment, the driving portion includes a driving motor 17, a driving pulley 16, a driven pulley 19, and a linear guide 29 disposed along the pressing direction, the moving portion includes a slider 36, and the oscillating assembly 27 is disposed on the linear guide 29 through the slider 36. The slider 36 is fitted to the linear guide 29, and can guide the movement of the moving part and restrict the movement locus of the moving part and the oscillating unit 27 provided on the moving part. A synchronous belt 20 is arranged between the driving pulley 16 and the driven pulley 19, the synchronous belt 20 is connected with a sliding block 36, the driving motor 17 drives the driving pulley 16 to rotate, and the driving pulley 16 drives the oscillating assembly 27 to slide on the linear guide rail 29 along with the sliding block 36 through the synchronous belt 20. Compared with gear transmission, the synchronous belt 20 is flexibly connected, and when the motion part is accidentally stuck, the impact on the driving motor 17 can be reduced. The synchronous belt 20 runs stably, has low noise and is suitable for being used in the environment of a laboratory and the like. Compared with belt transmission, the synchronous belt 20 transmission has the advantage of higher transmission precision, and can effectively ensure the position precision of the motion part.

Specifically, the driving portion further comprises a lifting plate 30, the linear guide rail 29 and the driving motor 17 are fixed on the lifting plate 30, the driven belt wheel 19 is rotatably arranged on the lifting plate 30, and the reset optical coupler 33 is also fixedly arranged on the lifting plate 30 corresponding to the starting position. A tension member 31 and a tension screw 32 are provided between the driven pulley 19 and the lifting plate 30, and the tension member 31 and the tension screw 32 are used to adjust the position of the driven pulley 19 and thus the tension degree of the timing belt 20. The lifter plate 30 can fix and restrain the relative positional relationship between the respective members of the driving part. The driving pulley 16 is arranged on a rotating shaft of the driving motor 17, and the driving pulley 16 is directly driven to rotate by the driving motor 17. The moving part further comprises a connecting piece 35, and the oscillating assembly 27 is connected with the sliding block 36 through the connecting piece 35.

In this embodiment, the buffer device 52 includes the rotating disc 12, the rotating disc 12 is provided with the position-limiting blocks 54 for placing the reaction containers 2 around the rotating axis of the rotating disc 12, and the working positions are correspondingly arranged on the rotating tracks of the position-limiting blocks 54, so that the rotating disc 12 can drive the reaction containers 2 in the position-limiting blocks 54 to move between the working positions during the rotating process.

One of the two working positions on the buffer device 52 is a mixing position, the other one is a sample adding position, and the suction needle assembly of the analyzer is arranged corresponding to the sample adding position and is used for adding samples into the reaction container 2. The work station can also comprise a feed station 46, in which feed station 46 the reaction vessels 2 are fed into a detent 54 of the rotary disk 12. In the rotating direction of the rotating disc 12, the sample adding position and the mixing position are sequentially arranged along the rotating disc 12. The tray feeding position 46 may be provided before the sample feeding position so that the reaction vessels 2 fed into the rotary tray 12 can be subjected to sample feeding processing.

In this embodiment, the working position further includes a detection position, and the detection position is disposed between the tray feeding position 46 and the sample adding position. The first detection unit is arranged in the detection position and is used for detecting whether the reaction container 2 is placed in the clamping position 54. The sample adding position is also provided with a second detection position unit. The second detection bit unit is used for detecting the condition of the reaction container 2 in the sample adding position. The screens 54 on the rotating disc 12 sequentially pass through the disc feeding position 46 and the detection position and then reach the sample feeding position, when the reaction container 2 cannot enter the corresponding screens 54 on the rotating disc 12 at the disc feeding position 46 due to reasons such as clamping stagnation of the reaction container 2, the empty screens 54 firstly pass through the detection position, and the first detection unit detects that no reaction cup exists on the screens 54 and triggers alarm stop. Specifically, the first detection unit and the second detection unit are both detection optocouplers 18, and when the detection optocouplers 18 detect that no reaction container 2 exists in the detection position, an alarm is triggered to stop. Prevent that empty screens 54 from rotating the application of sample position and carrying out the application of sample, cause the stained waste of equipment and reagent.

In this embodiment, the clamping portion 54 is a through hole provided on the rotating disc 12 and used for placing the reaction container 2, and when the oscillating assembly 27 oscillates the reaction container 2, the reaction container 2 can rock in the through hole, so as to uniformly mix the content in the reaction container 2. Specifically, reaction vessel 2 is last to set up with the spacing seat of through-hole complex, and the size of through-hole is greater than reaction vessel 2's size, and the size of spacing seat is greater than the size of through-hole, and reaction vessel 2 hangs on the through-hole through spacing seat, has the clearance between reaction vessel 2 and the through-hole. When the oscillating part moves towards the cup blocking component 3 and clamps the reaction vessel 2, the reaction vessel 2 and the limiting seat are lifted from the through hole. The clearance between the through-hole and the reaction vessel 2 can avoid interference with the rotating disk 12 when the reaction vessel 2 oscillates. The surface of cooperation can be the toper face between spacing seat and the through-hole, and the toper face can be fixed a position after leading reaction vessel 2 when reaction vessel 2 gets into the through-hole, guarantees reaction vessel 2's position accuracy.

In this embodiment, the working positions include a grasping position, and the grasping position is provided in the rotation direction of the rotating disk 12. After the grabbing position is arranged at the mixing position, the contents in the reaction container 2 are mixed uniformly, the reaction container is driven by the rotating disc 12 to rotate to the grabbing position, and the grabbing position is separated from the rotating disc 12 along the hole of the clamping position 54, so that the next detection step is carried out.

As shown in fig. 2, the buffer device 52 further includes a block, which is disposed corresponding to the grabbing position and is disposed on the rotation track of the position fastener 54, and the block protrudes toward the position fastener 54 for driving the reaction container 2 in the position fastener 54 to move along the hole of the position fastener 54. Specifically, the two sides of the block are provided with slopes in the rotation direction of the rotary disk 12, and when the reaction vessel 2 rotates to the grasping position, the reaction vessel 2 moves from the slopes to the block. Because the heightening block protrudes towards the clamping position 54, the heightening block can limit the reaction vessel 2 in the vertical direction, so that the rotating disc 12 cannot deform due to stress when the reaction vessel 2 is grabbed, and the stable grabbing of the reaction vessel is ensured.

The buffer device 52 further comprises a surrounding barrier 10, the surrounding barrier 10 is arranged along the edge of the rotating disc 12 in a circle, and the rotating disc 12 rotates in the surrounding barrier 10. As shown in fig. 10, a disc inlet opening 53 is formed on the edge of the rotary disc 12, and the disc inlet opening 53 communicates with the stopper 54. The skirt 10 cooperates with the edge of the rotatable disk 12 to restrain the reaction vessel 2 in the detent 54 and prevent the reaction vessel 2 from disengaging from the detent during rotation. The enclosure 10 is provided with a filling opening 8, the filling opening 8 is connected with a cup inlet flow channel, and the reaction container 2 in the cup inlet flow channel enters the clamping position 54 through the filling opening 8 and the tray inlet opening 53.

The screens 54 can be multiple, the number of the screens 54 is more than or equal to that of the working positions, and the screens 54 are arranged on the same circle by taking the rotation axis of the chuck as the center of a circle. The plurality of clamping positions 54 are arranged in a common circle, so that the positions of the clamping positions 54 after rotation are the same, and the clamping positions can be matched with the fixed working positions. When the number of the detents 54 is equal to the number of the working positions, each detent 54 is disposed corresponding to one working position, and the reaction vessels 2 corresponding to the number of the working positions can be buffered in the rotary disk 12. When the number of the detents 54 is greater than the number of the working positions, more reaction containers 2 can be buffered in the rotary plate 12, so as to increase the time between the reaction container 2 entering the buffering device 52 and leaving the buffering device 52, thereby achieving the effect of adjusting the detection time sequence of the reaction container 2. The plurality of clamping positions 54 are uniformly distributed on the rotating disc 12, so that the same distance between the adjacent clamping positions 54 is ensured, the clamping positions 54 can rotate at the same angle at each time, the rotating angle of the rotating disc 12 is convenient to control, and the rotating precision of the rotating disc 12 is improved.

Specifically, in this embodiment, the buffer device 52 further includes a buffer disk body 15 and a buffer disk bottom plate 42, and the enclosure 10 is disposed on the buffer disk body 15. As shown in fig. 2, a circular hole 11 is formed in the buffer disk body 15, and the oscillation assembly 27 passes through the circular hole 11 to oscillate the reaction vessel 2. The buffer disk bottom plate 42 is provided with a rotating motor 22 for driving the rotating disk 12 to rotate, a coded disk 44 is arranged on a rotating shaft of the rotating motor 22, and a position detection optical coupler 45 matched with the coded disk 44 is arranged on the buffer disk bottom plate 42. The position detection optocoupler 45 is matched with the coded disc 44 and is used for detecting the rotation angle of the rotating disc 12. A connecting shaft 43 is arranged between the rotating shaft of the rotating motor 22 and the rotating disc 12, and the rotating motor 22 drives the rotating disc 12 to rotate through the connecting shaft 43. The connecting shaft 43 penetrates through the buffer disc body 15, a connecting bearing is arranged between the buffer disc body 15 and the connecting shaft 43, and the buffer disc body 15 restrains and supports the connecting shaft 43 in the radial direction to ensure that the rotating disc 12 rotates stably.

The present embodiment further provides an operation method of the cache disk module, and provides the cache disk module 1, where the working positions are respectively set corresponding to one of the plurality of card positions 54, and the number of the card positions 54 is n. The method comprises the following steps: the rotating disc 12 is driven to rotate for a time, and the angle of a single rotation of the rotating disc 12 is 360 k/n. Where k may be equal to 1, or k is a positive integer other than 1 with the remainder of n/k being 1. I.e. the angle between k detents 54 for each rotation of the turn disc 12. The rotatable disk 12 is rotated k times and the detents 54 in the rotatable disk 12 complete one cycle.

Specifically, as shown in fig. 9, in the present embodiment, n is 11, and the number of the screens 54 is 11. The 11 screens 54 are uniformly distributed on the rotating disc 12 around the rotating axis of the rotating disc 12 and are sequentially from No. 1 to No. 11 along the rotating direction of the rotating disc 12. When k is 2, the rotating disc 12 rotates by an angle between 2 detents 54 each time, i.e., the rotating disc 12 rotates two times by 720/11 degrees in a single rotation, and the position 1 returns to the initial position, completing one cycle. In this embodiment, the working position includes a tray feeding position 46, a detection position 47, a sample adding position 48, a mixing position 49, and a grabbing position 50. In an initial state, the tray feeding position 46 corresponds to the position No. 1, the detection position 47 corresponds to the position No. 3, the sample adding position 48 corresponds to the position No. 6, the blending position 49 corresponds to the position No. 8, and the grabbing position 50 corresponds to the position No. 10. No. 2, No. 4, No. 5, No. 7, No. 9 and No. 11 are all corresponding to cache bits.

When the buffer disk module 1 starts to operate, the reaction vessel 2 enters the No. 1 position from the disk-entering position 46. The rotary disk 12 rotates, and the position No. 1 reaches the detection position 47, and the position No. 10 reaches the parking position 46. The detection opto-coupler 18 of the detection position 47 detects whether the reaction container 2 exists in the No. 1 position, and the No. 10 position is located at the tray-entering position 46 to be filled with the reaction container 2. After the above-mentioned action is completed, the rotating disk 12 rotates again, and passes through a plurality of buffer positions in turn until the position No. 1 reaches the sample adding position 48, and the suction needle assembly adds samples to the reaction containers 2 in the position No. 1. At this point, number 8 is in the cache bit. The rotating disc 12 rotates again, the position No. 1 reaches the blending position 49, at this time, the cup ejecting rod 28 rises to be matched with the cup blocking rod 13, the reaction container 2 is clamped between the cup ejecting rod 28 and the cup blocking rod 13, the cup ejecting rod 28 rotates to oscillate the reaction container 2, and the contents in the reaction container 2 are blended. The buffer tray bottom plate 42 is provided with a cleaning component 4, and the suction pins can finish cleaning at the cleaning component 4 after the sample adding position 48 adds samples to the reaction vessels 2. The rotary disk 12 is rotated again, the position No. 1 reaches the grasping position 50, and the reaction vessel 2 in the position No. 1 is removed, leaving the position No. 1 in an empty state. The rotating disc 12 continues to rotate and again reaches the intake position 46 for filling the reaction vessel 2, completing one cycle.

The embodiment also provides a sample analyzer, which comprises a suction needle module, an incubation disk module, a reagent disk module, a detector module and the above cache disk module 1. Wherein, the sucking needle module is used for sucking reagent or sample, and is placed in the reaction container 2 to become the object to be detected. The reagent disk module is used for storing reagents. The incubation disc module is used for incubating the object to be tested to enable the object to be tested to meet the conditions required by the reaction of the reagent and the sample. The detector module is used for detecting the object to be detected to obtain a detection result. The suction needle module is arranged corresponding to the suction position of the cache disk module 1, and reagent in the reagent disk module is added into the reaction vessel 2. The incubation disc module is used for placing the reaction container 2 grabbed by the grabber from the grabbing position to incubate, and the incubated reaction container 2 enters the detection module to be detected, so that the detection is completed.

Since the cache disk module 1 includes a content kneading device for kneading contents in the reaction vessel, the kneading device can knead the contents in the reaction vessel in the cache disk module 1. After the contents in the reaction container are mixed, the contents can react while being cached, so that the subsequent reaction time is reduced, the total detection time is shortened, and the detection efficiency is improved. Compared with a mixing device which is arranged independently, the buffer disk module 1 comprises the mixing device, so that a conveying mechanism is not required to be arranged between the buffer disk module 1 and the mixing device, the detection steps are simplified, the detection efficiency is improved, the structure of the analyzer is greatly simplified, and the volume and the production cost of the analyzer are reduced.

The foregoing embodiments are merely illustrative of the principles and utilities of the present invention and are not intended to limit the invention. Any person skilled in the art can modify or change the above-mentioned embodiments without departing from the spirit and scope of the present invention. Accordingly, it is intended that all equivalent modifications or changes which can be made by those skilled in the art without departing from the spirit and technical spirit of the present invention be covered by the claims of the present invention.

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