阅读说明：本技术 收获前干燥方法 (Pre-harvest drying method ) 是由 J·N·斯卡特 N·J·维勒茨 于 2020-02-04 设计创作，主要内容包括：披露了一种用于作物植物收获前干燥的方法,所述方法包括向这些作物植物施用有效量的具有式(I)的化合物或其农艺学上可接受的盐或两性离子物种,其中取代基如权利要求1中所定义。(A method for the pre-harvest drying of crop plants is disclosed, said method comprising applying to the crop plants an effective amount of a compound of formula (I) or an agronomically acceptable salt or zwitterionic species thereof, wherein the substituents are as defined in claim 1.)

1. A method for pre-harvest drying of crop plants, the method comprising applying to the crop plants an effective amount of a compound having formula (I):

wherein

R¹Selected from the group consisting of: hydrogen, halogen, C₁-C₆Alkyl radical, C₂-C₆Alkenyl radical, C₂-C₆Alkynyl, C₃-C₆Cycloalkyl radical, C₁-C₆Haloalkyl, -OR⁷、-OR^15a、-N(R⁶)S(O)₂R¹⁵、-N(R⁶)C(O)R¹⁵、-N(R⁶)C(O)OR¹⁵、-N(R⁶)C(O)NR¹⁶R¹⁷、-N(R⁶)CHO、-N(R^7a)₂and-S (O)_rR¹⁵；

R²Selected from the group consisting of: hydrogen, halogen, C₁-C₆Alkyl and C₁-C₆A haloalkyl group;

and wherein when R¹Selected from the group consisting of: -OR⁷、-OR^15a、-N(R⁶)S(O)₂R¹⁵、-N(R⁶)C(O)R¹⁵、-N(R⁶)C(O)OR¹⁵、-N(R⁶)C(O)NR¹⁶R¹⁷、-N(R⁶)CHO、-N(R^7a)₂and-S (O)_rR¹⁵When R is²Selected from the group consisting of: hydrogen and C₁-C₆An alkyl group; or

R¹And R²Together with the carbon atom to which they are attached form C₃-C₆A cycloalkyl ring or a 3-to 6-membered heterocyclyl group containing 1 or 2 heteroatoms independently selected from N and O;

q is (CR)^1aR^2b)_m；

m is 0, 1,2 or 3;

each R^1aAnd R^2bIndependently selected from the group consisting of: hydrogen, halogen, C₁-C₆Alkyl radical, C₁-C₆Haloalkyl, -OH, -OR⁷、-OR^15a、-NH₂、-NHR⁷、-NHR^15a、-N(R⁶)CHO、-NR^7bR^7cand-S (O)_rR¹⁵(ii) a Or

Each R^1aAnd R^2bTogether with the carbon atom to which they are attached form C₃-C₆A cycloalkyl ring or a 3-to 6-membered heterocyclyl, said heterocyclyl comprising 1 or 2 members independently selected from N and OA heteroatom of (a); and is

R³、R⁴And R⁵Independently selected from the group consisting of: hydrogen, halogen, cyano, nitro, -S (O)_rR¹⁵、C₁-C₆Alkyl radical, C₁-C₆Fluoroalkyl radical, C₁-C₆Fluoroalkoxy radical, C₁-C₆Alkoxy radical, C₃-C₆Cycloalkyl and-N (R)⁶)₂；

Each R⁶Independently selected from hydrogen and C₁-C₆An alkyl group;

each R⁷Independently selected from the group consisting of: c₁-C₆Alkyl, -S (O)₂R¹⁵、-C(O)R¹⁵、-C(O)OR¹⁵and-C (O) NR¹⁶R¹⁷；

Each R^7aIndependently selected from the group consisting of: -S (O)₂R¹⁵、-C(O)R¹⁵、-C(O)OR¹⁵、-C(O)NR¹⁶R¹⁷and-C (O) NR⁶R^15a；

R^7bAnd R^7cIndependently selected from the group consisting of: c₁-C₆Alkyl, -S (O)₂R¹⁵、-C(O)R¹⁵、-C(O)OR¹⁵、-C(O)NR¹⁶R¹⁷And phenyl, and wherein said phenyl is optionally substituted with 1,2 or 3R which may be the same or different⁹Substituent group substitution; or

R^7bAnd R^7cTogether with the nitrogen atom to which they are attached form a 4-to 6-membered heterocyclyl ring, optionally containing one additional heteroatom independently selected from N, O and S; and is

A is a 6-membered heteroaryl group comprising 1,2,3 or 4 nitrogen atoms, and wherein the heteroaryl group may optionally be substituted by 1,2,3 or 4R which may be the same or different⁸The substituent group is used for substitution,

and wherein when A is substituted with 1 or 2 substituents, each R⁸Independently selected from the group consisting of: halogen, nitro, cyano, -NH₂、-NHR⁷、-N(R⁷)₂、-OH、-OR⁷、-S(O)_rR¹⁵、-NR⁶S(O)₂R¹⁵、-C(O)OR¹⁰、-C(O)R¹⁵、-C(O)NR¹⁶R¹⁷、-S(O)₂NR¹⁶R¹⁷、C₁-C₆Alkyl radical, C₁-C₆Haloalkyl, C₃-C₆Cycloalkyl radical, C₃-C₆Halogenocycloalkyl, C₃-C₆Cycloalkoxy, C₂-C₆Alkenyl radical, C₂-C₆Haloalkenyl, C₂-C₆Alkynyl, C₁-C₃Alkoxy radical C₁-C₃Alkyl-, hydroxy-C_1-C₆Alkyl-, C₁-C₃Alkoxy radical C₁-C₃alkoxy-C₁-C₆Haloalkoxy, C₁-C₃Halogenoalkoxy radical C₁-C₃Alkyl-, C₃-C₆Alkenyloxy radical, C₃-C₆Alkynyloxy, N-C_3-C₆Cycloalkylamino, -C (R)⁶)＝NOR⁶Phenyl, a 3-to 6-membered heterocyclyl comprising 1 or 2 heteroatoms independently selected from N and O and a 5-or 6-membered heteroaryl comprising 1,2,3 or 4 heteroatoms independently selected from N, O and S, and wherein the phenyl, heterocyclyl or heteroaryl is optionally substituted with 1,2 or 3R which may be the same or different⁹Substituent group substitution;

and wherein when A is substituted with 3 or 4 substituents, each R⁸Independently selected from the group consisting of: halogen, -NH₂、-NHR⁷、-N(R⁷)₂、-OH、-OR⁷、-C(O)NR¹⁶R¹⁷、-S(O)₂NR¹⁶R¹⁷、C₁-C₆Alkyl and C₁-C₆A haloalkyl group; and is

Each R⁹Independently selected from the group consisting of: halogen, cyano, -OH, -N (R)⁶)₂、C₁-C₄Alkyl radical, C₁-C₄Alkoxy radical, C₁-C₄Haloalkyl and C₁-C₄A haloalkoxy group;

x is selected from the group consisting of: c₃-C₆Cycloalkyl, phenyl, a 5-or 6-membered heteroaryl group comprising 1,2,3 or 4 heteroatoms independently selected from N, O and S, and a 4-to 6-membered heterocyclyl group comprising 1,2 or 3 heteroatoms independently selected from N, O and S, and wherein the cycloalkyl, phenyl, heteroaryl or heterocyclyl moiety is optionally substituted with 1 or 2R⁹Is substituted by a substituent, and wherein CR is as defined above¹R²The Q and Z moieties may be attached at any position of the cycloalkyl, phenyl, heteroaryl or heterocyclyl moiety;

n is 0 or 1;

z is selected from the group consisting of: -C (O) OR¹⁰、-CH₂OH、-CHO、-C(O)NHOR¹¹、-C(O)NHCN、-OC(O)NHOR¹¹、-OC(O)NHCN、-NR⁶C(O)NHOR¹¹、-NR⁶C(O)NHCN、-C(O)NHS(O)₂R¹²、-OC(O)NHS(O)₂R¹²、-NR⁶C(O)NHS(O)₂R¹²、-S(O)₂OR¹⁰、-OS(O)₂OR¹⁰、-NR⁶S(O)₂OR¹⁰、-NR⁶S(O)OR¹⁰、-NHS(O)₂R¹⁴、-S(O)OR¹⁰、-OS(O)OR¹⁰、-S(O)₂NHCN、-S(O)₂NHC(O)R¹⁸、-S(O)₂NHS(O)₂R¹²、-OS(O)₂NHCN、-OS(O)₂NHS(O)₂R¹²、-OS(O)₂NHC(O)R¹⁸、-NR⁶S(O)₂NHCN、-NR⁶S(O)₂NHC(O)R¹⁸、-N(OH)C(O)R¹⁵、-ONHC(O)R¹⁵、-NR⁶S(O)₂NHS(O)₂R¹²、-P(O)(R¹³)(OR¹⁰)、-P(O)H(OR¹⁰)、-OP(O)(R¹³)(OR¹⁰)、-NR⁶P(O)(R¹³)(OR¹⁰) And tetrazole;

R¹⁰selected from the group consisting of: hydrogen, C₁-C₆Alkyl, phenyl and benzyl, and wherein said phenyl or benzylOptionally substituted by 1,2 or 3R which may be the same or different⁹Substituent group substitution;

R¹¹selected from the group consisting of: hydrogen, C₁-C₆Alkyl and phenyl, and wherein the phenyl is optionally substituted with 1,2 or 3R which may be the same or different⁹Substituent group substitution;

R¹²selected from the group consisting of: c₁-C₆Alkyl radical, C₁-C₆Haloalkyl, C₁-C₆Alkoxy, -OH, -N (R)⁶)₂And phenyl, and wherein said phenyl is optionally substituted with 1,2 or 3R which may be the same or different⁹Substituent group substitution;

R¹³selected from the group consisting of: -OH, C₁-C₆Alkyl radical, C₁-C₆Alkoxy and phenyl;

R¹⁴is C₁-C₆A haloalkyl group;

R¹⁵selected from the group consisting of: c₁-C₆Alkyl and phenyl, and wherein the phenyl is optionally substituted with 1,2 or 3R which may be the same or different⁹Substituent group substitution;

R^15ais phenyl, wherein the phenyl is optionally substituted by 1,2 or 3R which may be the same or different⁹Substituent group substitution;

R¹⁶and R¹⁷Independently selected from the group consisting of: hydrogen and C₁-C₆An alkyl group; or

R¹⁶And R¹⁷Together with the nitrogen atom to which they are attached form a 4-to 6-membered heterocyclyl ring, optionally containing one additional heteroatom independently selected from N, O and S; and is

R¹⁸Selected from the group consisting of: hydrogen, C₁-C₆Alkyl radical, C₁-C₆Haloalkyl, C₁-C₆Alkoxy, -N (R)⁶)₂And phenyl, and wherein said phenyl is optionally substituted with 1,2 or 3R which may be the same or different⁹Substituent group substitution;

and is

r is 0, 1 or 2.

2. The method of claim 1, wherein R¹And R²Independently selected from the group consisting of: hydrogen and C₁-C₆An alkyl group.

3. The method of claim 1 or claim 2, wherein each R is^1aAnd R^2bIndependently selected from the group consisting of: hydrogen, C₁-C₆Alkyl, -OH and-NH₂。

4. The method of any one of claims 1 to 3, wherein m is 1 or 2.

5. The method of any one of claims 1 to 4, wherein R³、R⁴And R⁵Independently selected from the group consisting of: hydrogen, C₁-C₆Alkyl and C₁-C₆An alkoxy group.

6. The method of any one of claims 1 to 5, wherein R³、R⁴And R⁵Is hydrogen.

7. The method of any one of claims 1 to 6, wherein A is selected from the group consisting of: of the formulae A-I to A-VII

Wherein the jagged line defines the attachment point to the remainder of the compound having formula (I), p is 0, 1, or 2, and R is⁸As defined in claim 1.

8. The method of any one of claims 1 to 7, wherein A is selected from the group consisting of: of the formulae A-I to A-V

Wherein the jagged line defines the attachment point to the remainder of the compound having formula (I), p is 0, 1, or 2, and R is⁸As defined in claim 1.

9. The method of any one of claims 1 to 8, wherein each R, when A is substituted with 1 or 2 substituents⁸Independently selected from the group consisting of: halogen, nitro, cyano, -NH₂、-NHR⁷、-N(R⁷)₂、-OH、-OR⁷、-S(O)_rR¹⁵、-NR⁶S(O)₂R¹⁵、-C(O)OR¹⁰、-C(O)R¹⁵、-C(O)NR¹⁶R¹⁷、-S(O)₂NR¹⁶R¹⁷、C₁-C₆Alkyl and C₁-C₆A haloalkyl group.

10. The method of any one of claims 1 to 9, wherein each R, when A is substituted with 1 or 2 substituents⁸Independently selected from the group consisting of: chloro, fluoro, cyano, -NH₂、-N(Me)₂、-OMe、-S(O)₂Me、-C(O)NHMe、-C(O)N(Me)₂Methyl and trifluoromethyl.

11. The method of any one of claims 1 to 10, wherein a is selected from the group consisting of: formulae A-I to A-V, and p is 0.

12. The method of any one of claims 1 to 11, wherein Z is selected from the group consisting of: -C (O) OR¹⁰、-C(O)NHS(O)₂R¹²、-S(O)₂OR¹⁰and-P (O) (R)¹³)(OR¹⁰)。

13. The method of any one of claims 1 to 12, wherein Z is-C (O) OH or-S (O)₂OH。

14. The method of any one of claims 1 to 13, wherein n is 0.

15. The method according to any one of the preceding claims, wherein the compound of formula (I) is applied to the crop plant when fully grown up and shortly before harvesting.

16. A desiccant composition comprising a herbicidally effective amount of a compound of formula (I) as defined in any one of claims 1 to 15 and an agrochemically acceptable diluent or carrier.