阅读说明：本技术 一种含有虾青素的多效牙膏及其制备方法 (Multi-effect toothpaste containing astaxanthin and preparation method thereof ) 是由 曾赛璐 黄奕筝 于 2021-07-02 设计创作，主要内容包括：本发明涉及牙膏技术领域,尤其涉及一种含有虾青素的多效牙膏,其按重量份,包括以下组分：聚乙二醇400为3～5份、甘油为15～25份、磷酸氢钙为40～45份、虾青素为0.8～1.2份、黄原胶为1～2份、月桂酰肌氨酸钠为2～4份、薄荷醇为0.1～0.5份、苯甲酸钠为0.2～0.5份、焦磷酸钠为0.3～0.5份和去离子水为16.3～37.6份。本发明还提出了一种含有虾青素的多效牙膏的制备方法。本发明提供的多效牙膏能满足消费者对口腔健康护理的需求。(The invention relates to the technical field of toothpaste, in particular to multi-effect toothpaste containing astaxanthin, which comprises the following components in parts by weight: 3-5 parts of polyethylene glycol 400, 15-25 parts of glycerol, 40-45 parts of calcium hydrophosphate, 0.8-1.2 parts of astaxanthin, 1-2 parts of xanthan gum, 2-4 parts of sodium lauroyl sarcosinate, 0.1-0.5 part of menthol, 0.2-0.5 part of sodium benzoate, 0.3-0.5 part of sodium pyrophosphate and 16.3-37.6 parts of deionized water. The invention also provides a preparation method of the multi-effect toothpaste containing astaxanthin. The multi-effect toothpaste provided by the invention can meet the requirements of consumers on oral health care.)

1. The multi-effect toothpaste containing astaxanthin is characterized by comprising the following components in parts by weight: 3-5 parts of polyethylene glycol 400, 15-25 parts of glycerol, 40-45 parts of calcium hydrophosphate, 0.8-1.2 parts of astaxanthin, 1-2 parts of xanthan gum, 2-4 parts of sodium lauroyl sarcosinate, 0.1-0.5 part of menthol, 0.2-0.5 part of sodium benzoate, 0.3-0.5 part of sodium pyrophosphate and 16.3-37.6 parts of deionized water.

2. The multi-effect toothpaste containing astaxanthin according to claim 1, which comprises the following components in parts by weight: 3 parts of polyethylene glycol 400, 15 parts of glycerol, 40 parts of calcium hydrophosphate, 0.8 part of astaxanthin, 1 part of xanthan gum, 2 parts of sodium lauroyl sarcosinate, 0.1 part of menthol, 0.2 part of sodium benzoate, 0.3 part of sodium pyrophosphate and 16.3 parts of deionized water.

3. The multi-effect toothpaste containing astaxanthin according to claim 1, which comprises the following components in parts by weight: 4 parts of polyethylene glycol 400, 20 parts of glycerol, 42 parts of calcium hydrophosphate, 1 part of astaxanthin, 1.5 parts of xanthan gum, 3 parts of sodium lauroyl sarcosinate, 0.3 part of menthol, 0.3 part of sodium benzoate, 0.4 part of sodium pyrophosphate and 25 parts of deionized water.

4. The multi-effect toothpaste containing astaxanthin according to claim 1, which comprises the following components in parts by weight: 5 parts of polyethylene glycol 400, 25 parts of glycerol, 45 parts of calcium hydrophosphate, 1.2 parts of astaxanthin, 2 parts of xanthan gum, 4 parts of sodium lauroyl sarcosinate, 0.5 part of menthol, 0.5 part of sodium benzoate, 0.5 part of sodium pyrophosphate and 37.6 parts of deionized water.

5. The multi-effect toothpaste containing astaxanthin according to claim 1, wherein the preparation method of astaxanthin comprises the following steps:

s51, crushing the clean shrimp shells;

s52, adding acid liquor into the crushed shrimp shells for soaking;

s53, taking out the shrimp shells soaked in the acid liquor, and washing the shrimp shells to be neutral by using alkali liquor;

s54, drying the neutral shrimp shells, and performing circulating extraction by using supercritical static extraction equipment to obtain an extract X;

s55, saponifying the extract X to obtain a saponified substance Y;

s56, carrying out liquid chromatography analysis and purification on the saponified substance Y to obtain astaxanthin; the astaxanthin obtained was stored frozen.

6. The multi-effect toothpaste containing astaxanthin according to claim 5, wherein the temperature at which the extraction is carried out using the supercritical static extraction apparatus in S54 is 80 ℃ and the pressure is 40 MPa.

7. The preparation method of the multiple-effect toothpaste containing astaxanthin is characterized by comprising the following specific steps:

s1, weighing polyethylene glycol 400, glycerol, calcium hydrophosphate, astaxanthin, xanthan gum, sodium lauroyl sarcosinate, menthol, sodium benzoate, sodium pyrophosphate and deionized water according to parts by weight;

s2, adding sodium benzoate, sodium pyrophosphate and sodium lauroyl sarcosinate into deionized water for dissolving to obtain a mixed solution A;

s3, adding glycerol, sodium pyrophosphate and xanthan gum into the mixed solution A to obtain a mixed solution B;

s4, adding menthol into polyethylene glycol 400 to dissolve to obtain a mixed solution C;

s5, adding the mixed solution C into the mixed solution B, and uniformly stirring to obtain a paste D;

s6, cooling the paste D, adding astaxanthin into the paste D, and uniformly stirring to obtain a paste E;

and S7, vacuumizing the paste E to obtain a finished paste F.

8. The method for preparing a multi-effect toothpaste containing astaxanthin according to claim 7, wherein the temperature of the S6 and the medium paste body D after cooling is not higher than 40 ℃.

Technical Field

The invention relates to the technical field of toothpaste, in particular to multi-effect toothpaste containing astaxanthin and a preparation method thereof.

Background

Toothpaste is one of tooth cleaning products, is generally in a gel shape, is usually smeared on a toothbrush, cleans the surfaces of teeth by the mechanical friction action of the toothbrush, cleans the teeth and the periphery of the teeth and enables the oral cavity to be clean and fresh; the existing toothpaste is only added with components such as mint and the like, so that a consumer can refresh breath after using the toothpaste, but along with the demand of the consumer on oral health, the existing toothpaste cannot meet the demand of the consumer on toothpaste capable of improving oral health.

Disclosure of Invention

In order to solve the technical problems in the background art, the invention provides the multi-effect toothpaste containing the astaxanthin and the preparation method thereof, and the multi-effect toothpaste prepared by the multi-effect toothpaste components and the preparation method of the multi-effect toothpaste can meet the requirements of consumers on oral health care.

In order to solve the problems, the invention provides a multi-effect toothpaste containing astaxanthin, which comprises the following components in parts by weight: 3-5 parts of polyethylene glycol 400, 15-25 parts of glycerol, 40-45 parts of calcium hydrophosphate, 0.8-1.2 parts of astaxanthin, 1-2 parts of xanthan gum, 2-4 parts of sodium lauroyl sarcosinate, 0.1-0.5 part of menthol, 0.2-0.5 part of sodium benzoate, 0.3-0.5 part of sodium pyrophosphate and 16.3-37.6 parts of deionized water.

Preferably, the multi-effect toothpaste containing astaxanthin comprises the following components in parts by weight: 3 parts of polyethylene glycol 400, 15 parts of glycerol, 40 parts of calcium hydrophosphate, 0.8 part of astaxanthin, 1 part of xanthan gum, 2 parts of sodium lauroyl sarcosinate, 0.1 part of menthol, 0.2 part of sodium benzoate, 0.3 part of sodium pyrophosphate and 16.3 parts of deionized water.

Preferably, the multi-effect toothpaste containing astaxanthin comprises the following components in parts by weight: 4 parts of polyethylene glycol 400, 20 parts of glycerol, 42 parts of calcium hydrophosphate, 1 part of astaxanthin, 1.5 parts of xanthan gum, 3 parts of sodium lauroyl sarcosinate, 0.3 part of menthol, 0.3 part of sodium benzoate, 0.4 part of sodium pyrophosphate and 25 parts of deionized water.

Preferably, the multi-effect toothpaste containing astaxanthin comprises the following components in parts by weight: 5 parts of polyethylene glycol 400, 25 parts of glycerol, 45 parts of calcium hydrophosphate, 1.2 parts of astaxanthin, 2 parts of xanthan gum, 4 parts of sodium lauroyl sarcosinate, 0.5 part of menthol, 0.5 part of sodium benzoate, 0.5 part of sodium pyrophosphate and 37.6 parts of deionized water.

Preferably, the preparation method of astaxanthin comprises the following steps:

s51, crushing the clean shrimp shells;

s52, adding acid liquor into the crushed shrimp shells for soaking;

s53, taking out the shrimp shells soaked in the acid liquor, and washing the shrimp shells to be neutral by using alkali liquor;

s54, drying the neutral shrimp shells, and performing circulating extraction by using supercritical static extraction equipment to obtain an extract X;

s55, saponifying the extract X to obtain a saponified substance Y;

s56, carrying out liquid chromatography analysis and purification on the saponified substance Y to obtain astaxanthin; the astaxanthin obtained was stored frozen.

Preferably, the temperature of the supercritical static extraction device used for extraction in S54 is 80 ℃, and the pressure is 40 MPa.

The invention also provides a preparation method of the multiple-effect toothpaste containing astaxanthin, which comprises the following specific steps:

s1, weighing polyethylene glycol 400, glycerol, calcium hydrophosphate, astaxanthin, xanthan gum, sodium lauroyl sarcosinate, menthol, sodium benzoate, sodium pyrophosphate and deionized water according to parts by weight;

s2, adding sodium benzoate, sodium pyrophosphate and sodium lauroyl sarcosinate into deionized water for dissolving to obtain a mixed solution A;

s3, adding glycerol, sodium pyrophosphate and xanthan gum into the mixed solution A to obtain a mixed solution B;

s4, adding menthol into polyethylene glycol 400 to dissolve to obtain a mixed solution C;

s5, adding the mixed solution C into the mixed solution B, and uniformly stirring to obtain a paste D;

s6, cooling the paste D, adding astaxanthin into the paste D, and uniformly stirring to obtain a paste E;

and S7, vacuumizing the paste E to obtain a finished paste F.

Preferably, the temperature of the S6 and the medium paste D after temperature reduction is not higher than 40 DEG C

The technical scheme of the invention has the following beneficial technical effects:

the astaxanthin-containing multi-effect toothpaste provided by the invention is added with astaxanthin; the astaxanthin has the characteristics of oxidation resistance, colorability and organism immunity enhancement, and further can effectively improve the health care of the toothpaste to the oral cavity of a human body;

the multi-effect toothpaste containing astaxanthin provided by the invention is added with menthol; the menthol has mint fragrance, has an anti-inflammatory effect and can effectively treat oral diseases;

the multi-effect toothpaste containing astaxanthin provided by the invention is added with polyethylene glycol 400; the polyethylene glycol 400 can ensure that the raw materials for preparing the multi-effect toothpaste are uniformly dispersed and mixed so as to improve the quality of the toothpaste;

the glycerol is added into the multiple-effect toothpaste containing the astaxanthin to prevent the toothpaste from softening, so that the toothpaste has luster;

the calcium hydrogen phosphate is added into the multiple-effect toothpaste containing the astaxanthin to produce a good remineralization repairing effect on the damaged teeth;

the multiple-effect toothpaste containing astaxanthin provided by the invention is added with sodium benzoate; the sodium benzoate has antiseptic effect, and can also be used as astaxanthin activity stabilizer.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments.

Example 1

The invention provides a multi-effect toothpaste containing astaxanthin, which comprises the following components in parts by weight: 3 parts of polyethylene glycol 400, 15 parts of glycerol, 40 parts of calcium hydrophosphate, 0.8 part of astaxanthin, 1 part of xanthan gum, 2 parts of sodium lauroyl sarcosinate, 0.1 part of menthol, 0.2 part of sodium benzoate, 0.3 part of sodium pyrophosphate and 16.3 parts of deionized water.

In an alternative embodiment, the method comprises the following steps:

s51, crushing the clean shrimp shells;

s52, adding acid liquor into the crushed shrimp shells for soaking;

s53, taking out the shrimp shells soaked in the acid liquor, and washing the shrimp shells to be neutral by using alkali liquor;

s54, drying the neutral shrimp shells, and performing circulating extraction by using supercritical static extraction equipment to obtain an extract X;

s55, saponifying the extract X to obtain a saponified substance Y;

s56, carrying out liquid chromatography analysis and purification on the saponified substance Y to obtain astaxanthin; the astaxanthin obtained was stored frozen.

In an alternative embodiment, the temperature of the extraction in S54 using the supercritical static extraction apparatus is 80 ℃ and the pressure is 40 MPa.

Example 2

The invention provides a multi-effect toothpaste containing astaxanthin, which comprises the following components in parts by weight: 4 parts of polyethylene glycol 400, 20 parts of glycerol, 42 parts of calcium hydrophosphate, 1 part of astaxanthin, 1.5 parts of xanthan gum, 3 parts of sodium lauroyl sarcosinate, 0.3 part of menthol, 0.3 part of sodium benzoate, 0.4 part of sodium pyrophosphate and 25 parts of deionized water.

In an alternative embodiment, the method comprises the following steps:

s51, crushing the clean shrimp shells;

s52, adding acid liquor into the crushed shrimp shells for soaking;

s53, taking out the shrimp shells soaked in the acid liquor, and washing the shrimp shells to be neutral by using alkali liquor;

s54, drying the neutral shrimp shells, and performing circulating extraction by using supercritical static extraction equipment to obtain an extract X;

s55, saponifying the extract X to obtain a saponified substance Y;

s56, carrying out liquid chromatography analysis and purification on the saponified substance Y to obtain astaxanthin; the astaxanthin obtained was stored frozen.

In an alternative embodiment, the temperature of the extraction in S54 using the supercritical static extraction apparatus is 80 ℃ and the pressure is 40 MPa.

Example 3

The invention provides a multi-effect toothpaste containing astaxanthin, which comprises the following components in parts by weight: 5 parts of polyethylene glycol 400, 25 parts of glycerol, 45 parts of calcium hydrophosphate, 1.2 parts of astaxanthin, 2 parts of xanthan gum, 4 parts of sodium lauroyl sarcosinate, 0.5 part of menthol, 0.5 part of sodium benzoate, 0.5 part of sodium pyrophosphate and 37.6 parts of deionized water.

In an alternative embodiment, the method comprises the following steps:

s51, crushing the clean shrimp shells;

s52, adding acid liquor into the crushed shrimp shells for soaking;

s53, taking out the shrimp shells soaked in the acid liquor, and washing the shrimp shells to be neutral by using alkali liquor;

s54, drying the neutral shrimp shells, and performing circulating extraction by using supercritical static extraction equipment to obtain an extract X;

s55, saponifying the extract X to obtain a saponified substance Y;

s56, carrying out liquid chromatography analysis and purification on the saponified substance Y to obtain astaxanthin; the astaxanthin obtained was stored frozen.

In an alternative embodiment, the temperature of the extraction in S54 using the supercritical static extraction apparatus is 80 ℃ and the pressure is 40 MPa.

Example 4

The preparation method of the multiple-effect toothpaste containing astaxanthin provided by the invention comprises the multiple-effect toothpaste containing astaxanthin provided by the embodiment 1 or the embodiment 2 or the embodiment 3, and specifically comprises the following steps:

s1, weighing polyethylene glycol 400, glycerol, calcium hydrophosphate, astaxanthin, xanthan gum, sodium lauroyl sarcosinate, menthol, sodium benzoate, sodium pyrophosphate and deionized water according to parts by weight;

s2, adding sodium benzoate, sodium pyrophosphate and sodium lauroyl sarcosinate into deionized water for dissolving to obtain a mixed solution A;

s3, adding glycerol, sodium pyrophosphate and xanthan gum into the mixed solution A to obtain a mixed solution B;

s4, adding menthol into polyethylene glycol 400 to dissolve to obtain a mixed solution C;

s5, adding the mixed solution C into the mixed solution B, and uniformly stirring to obtain a paste D;

s6, cooling the paste D, adding astaxanthin into the paste D, and uniformly stirring to obtain a paste E;

and S7, vacuumizing the paste E to obtain a finished paste F.

In an alternative embodiment, the temperature of the paste D after cooling in the S6 process is not higher than 40 ℃.