Magnetic resonance spectrometer with integrated and distributed combined structure

文档序号:271212 发布日期:2021-11-19 浏览:9次 中文

阅读说明:本技术 一种具有集成与分布式结合结构的磁共振谱仪 (Magnetic resonance spectrometer with integrated and distributed combined structure ) 是由 蔡昕 王君杰 张丙春 尹德坤 温宇辰 富卓 赵勇 于 2021-08-12 设计创作,主要内容包括:本发明公开了一种具有集成与分布式结合结构的磁共振谱仪,属于磁共振谱仪技术领域。包括集成有多个功能电路的单板扫描控制单元、数据通信单元以及多路并行的数据接收单元;所述数据通信单元向上与上位机相连,所述单板扫描控制单元向上与数据通信单元相连,所述单板扫描控制单元向下与多路并行的数据接收单元相连。通过本发明,提供一种具有集成与分布式结合结构的磁共振谱仪,包含集成各功能电路的单板扫描控制单元、数据通信单元以及多路并行的数据接收单元,一套磁共振谱仪可以灵活适配各种不同配置和定位的磁共振系统,有极高的兼容性。(The invention discloses a magnetic resonance spectrometer with an integrated and distributed combined structure, and belongs to the technical field of magnetic resonance spectrometers. The system comprises a single board scanning control unit integrated with a plurality of functional circuits, a data communication unit and a plurality of paths of parallel data receiving units; the data communication unit is upwards connected with the upper computer, the single board scanning control unit is upwards connected with the data communication unit, and the single board scanning control unit is downwards connected with the multi-channel parallel data receiving unit. The invention provides a magnetic resonance spectrometer with an integrated and distributed combined structure, which comprises a single-board scanning control unit, a data communication unit and a multi-channel parallel data receiving unit, wherein all functional circuits are integrated, and the magnetic resonance spectrometer can be flexibly adapted to various magnetic resonance systems with different configurations and positions and has extremely high compatibility.)

1. A magnetic resonance spectrometer with integrated and distributed combined structure is characterized by comprising a single-board scanning control unit, a data communication unit and a multi-channel parallel data receiving unit, wherein the single-board scanning control unit is integrated with a plurality of functional circuits;

the data communication unit is upwards connected with an upper computer, the single-board scanning control unit is upwards connected with the data communication unit, and the single-board scanning control unit is downwards connected with the multi-channel parallel data receiving unit;

the data communication unit comprises a controller for controlling data exchange, a computer interface for exchanging information with a computer mainboard, a special interface for communicating with the single-board scanning control unit and a special interface for communicating with the magnetic resonance gate control trigger unit;

a plurality of functional circuits on the single-board scanning control unit are connected through PCB board-level connecting lines and integrated in a PCB board, wherein the functional circuits comprise a synchronous clock circuit, a data analysis controller, a special interface circuit for exchanging data with the data communication unit, a radio frequency transmitting circuit, a gradient driving circuit and a data receiving circuit; the data communication unit is connected with the special interface circuit through a special interface communicated with the single-board scanning control unit;

the data receiving unit is composed of a special interface communicated with the single board scanning control unit, a data controller and a plurality of analog receiving channels, the data controller is connected with a data receiving circuit of the single board scanning control unit through the special interface, and the data controller is respectively connected with the analog receiving channels.

2. The apparatus according to claim 1, wherein each functional circuit of the single-board scan control unit has both digital and analog interfaces.

3. The magnetic resonance spectrometer with integrated and distributed combined structure as claimed in claim 1, wherein the synchronous clock circuit is respectively connected to the data analysis controller, the rf transmitter circuit, the gradient driver circuit, the data receiver circuit, the data communication unit and the multiple parallel data receiver units of the single board scan control unit.

4. The magnetic resonance spectrometer with integrated and distributed combined structure as claimed in claim 1, wherein the computer interface of the data communication unit employs a PCIe communication interface.

Technical Field

The invention relates to a magnetic resonance spectrometer with an integrated and distributed combined structure, and belongs to the technical field of magnetic resonance spectrometers.

Background

Magnetic Resonance Imaging (MRI) technology is an important medical image diagnostic method, and Magnetic Resonance Imaging equipment acquires Magnetic Resonance signals generated after nuclei are excited by radio frequency in a static Magnetic field and presents images after post-processing.

The magnetic resonance spectrometer is a core control component of the magnetic resonance imaging equipment and is responsible for generating a radio frequency signal for radio frequency excitation and a gradient waveform signal for spatial positioning, controlling a power device of the magnetic resonance equipment to work, receiving a magnetic resonance signal received from a radio frequency receiving coil, carrying out a series of signal processing, and then sending the signal to a computer system for reconstruction to generate a magnetic resonance image. The existing magnetic resonance spectrometers on the market at present basically realize the digitization of signals, the modularization of structures and the fibering of interconnection media.

Most of the prior magnetic resonance spectrometers have the following structures: different function execution circuits are subdivided into different modules, and the modules are interconnected and exchange data through a backplane physical bus pin structure or an optical fiber interface structure. The distribution structure causes the problems that the spectrometer system is complex in connection and the connection among the modules is unreliable, and brings troubles to system integration and system stability. The increase in interconnection interfaces also results in an increase in spectrometer cost. In view of this, a magnetic resonance spectrometer architecture that integrates and distributes in combination is proposed.

Disclosure of Invention

In order to solve the above technical problems, it is an object of the present invention to provide a magnetic resonance spectrometer having an integrated and distributed combined structure.

The technical problem to be solved by the invention is realized by adopting the following technical scheme:

a magnetic resonance spectrometer with integrated and distributed combined structure comprises a single-board scanning control unit integrated with a plurality of functional circuits, a data communication unit and a multi-channel parallel data receiving unit;

the data communication unit is upwards connected with an upper computer, the single-board scanning control unit is upwards connected with the data communication unit, and the single-board scanning control unit is downwards connected with the multi-channel parallel data receiving unit;

the data communication unit comprises a controller for controlling data exchange, a computer interface for exchanging information with a computer mainboard, a special interface for communicating with the single-board scanning control unit and a special interface for communicating with the magnetic resonance gate control trigger unit;

a plurality of functional circuits on the single-board scanning control unit are connected through PCB board-level connecting lines and integrated in a PCB board, wherein the functional circuits comprise a synchronous clock circuit, a data analysis controller, a special interface circuit for exchanging data with the data communication unit, a radio frequency transmitting circuit, a gradient driving circuit and a data receiving circuit; the data communication unit is connected with the special interface circuit through a special interface communicated with the single-board scanning control unit;

the data receiving unit is composed of a special interface communicated with the single board scanning control unit, a data controller and a plurality of analog receiving channels, the data controller is connected with a data receiving circuit of the single board scanning control unit through the special interface, and the data controller is respectively connected with the analog receiving channels.

As a preferred example, each functional circuit of the single-board scanning control unit is provided with two interfaces, namely a digital interface and an analog interface.

As a preferred example, the synchronous clock circuit is respectively connected to the data analysis controller, the radio frequency transmitting circuit, the gradient driving circuit, the data receiving circuit, the data communication unit and the multiple parallel data receiving units of the single board scanning control unit.

As a preferred example, the computer interface of the data communication unit adopts a PCIe communication interface.

The invention has the beneficial effects that:

(1) the invention provides a magnetic resonance spectrometer with an integrated and distributed combined structure, which comprises a single-board scanning control unit, a data communication unit and a multi-channel parallel data receiving unit, wherein all functional circuits are integrated, and the magnetic resonance spectrometer can be flexibly adapted to various magnetic resonance systems with different configurations and positions and has extremely high compatibility;

(2) the communication among the modules of the single-board scanning control unit is connected through board-level lines, so that the processing precision is high, the connection is stable, poor connection caused by external force, environment and other problems can be avoided, the signal integrity can be kept to the maximum extent, and the stability and the signal quality of the spectrometer are improved;

(3) each functional circuit of the single-board scanning control unit is provided with a digital interface and an analog interface, and can be adapted to different types of rear-stage power devices and analog receiving links;

(4) the synchronous clock circuit connects the clock signal to each functional circuit of the single-board scanning control unit and the data communication unit and the data receiving unit thereof, thereby ensuring that the clocks among the units are in the same source and phase, improving the precision of sequence scanning and improving the image quality;

(5) the interface of the data communication unit and the computer uses a common PCIe communication interface, has good compatibility and can be accessed to special computers with different functions;

(6) the data receiving unit can work in parallel in multiple groups and can be gated by any channel combination.

Drawings

FIG. 1 is a schematic diagram of the general structure of a magnetic resonance spectrometer of the present invention;

FIG. 2 is a schematic diagram of a data communication unit of the magnetic resonance spectrometer of the present invention;

FIG. 3 is a schematic structural diagram of a single-plate scanning control unit in the magnetic resonance spectrometer according to the present invention;

FIG. 4 is a schematic diagram of a data receiving unit of the magnetic resonance spectrometer of the present invention;

FIG. 5 is a schematic structural diagram of a first installation mode of a data receiving unit in the magnetic resonance spectrometer according to the present invention;

FIG. 6 is a schematic structural diagram of a second embodiment of a data receiving unit of the magnetic resonance spectrometer;

FIG. 7 is a schematic structural diagram of a third embodiment of a data receiving unit of the magnetic resonance spectrometer of the present invention.

Detailed Description

In order to make the technical means, the original characteristics, the achieved purpose and the efficacy of the invention easy to understand, the invention is further described with reference to the specific drawings and the embodiments.

Example (b):

as shown in fig. 1-7, the present invention provides an integrated control and distributed combination magnetic resonance spectrometer. Specifically, as shown in fig. 1, the system includes a single board scan control unit, a data communication unit, and a multi-channel parallel data receiving unit, which integrate each functional circuit. The data communication unit receives the sequence execution data packet sent by the upper computer and sends the sequence execution data packet to the single board scanning control unit. The single board scanning control unit receives the sequence execution data packet issued by the data communication unit, stores and analyzes different types of hardware execution data in the data packet, and distributes the hardware execution data to different functional circuits in the single board for execution. Meanwhile, the single board scanning control unit can also send the execution data of the receiving type to a plurality of signal receiving units which work in parallel and are positioned in the shielding room. The data receiving unit working in parallel can acquire magnetic resonance signals according to the configuration issued by the scanning control unit, and transmits the data to the single-board scanning control unit in parallel after AD conversion. The single-board scanning control unit uploads the data to an upper computer through a data communication unit for reconstruction and post-processing of the magnetic resonance image.

The data communication unit can be integrated in special computers with different functions to adapt to magnetic resonance systems with different computer structures, such as an operating computer used by a user or a reconstruction computer responsible for image reconstruction. As shown in fig. 2, it includes four parts, namely a controller for controlling data exchange, a communication interface for exchanging information with a computer motherboard, a dedicated interface for communicating with a single board scanning control unit, and a dedicated interface for communicating with a magnetic resonance gate control trigger unit. Wherein the controller may be one or several combinations of FPGA or other embedded chips of Altera corporation or Xilinx corporation. The communication interface for exchanging information with the computer may be a PCIe interface. The high-speed special interface for communicating with the single-board scanning control unit can be a high-speed serial optical fiber interface of a self-defined protocol.

The special interface for communicating with the gating trigger unit can be one or a combination of several interfaces such as a custom protocol optical fiber interface, a coaxial cable interface or a standard protocol serial communication interface.

The single-board scanning control unit is a core hardware control execution component in the magnetic resonance sequence scanning process. The hardware execution instruction data packet sent by the data communication unit is received, different types of hardware execution data in the data packet are stored and analyzed, and the hardware execution data are distributed to different functional circuits in a single board for execution, or relevant instruction data packets are sent to other hardware execution units through a special interface after being analyzed. As shown in fig. 3, the single board scanning control unit adopts a single board PCB design, integrates each functional circuit into one PCB board, and includes the following functional circuits: the system comprises a synchronous clock circuit, a data analysis controller, a special interface circuit for exchanging data with a data communication unit, a radio frequency transmitting circuit, a gradient driving circuit and a data receiving circuit.

And all modules of the single-board scanning control unit are directly connected through PCB (printed circuit board) level lines.

The synchronous clock circuit takes a high-precision constant-temperature crystal oscillator as a core, is used for generating a plurality of paths of high-precision synchronous clocks, is simultaneously distributed to a data analysis controller, a radio frequency transmitting circuit, a gradient driving circuit and a data receiving circuit in a single scanning control unit, and is also simultaneously distributed to a data communication unit and a plurality of independent data receiving units, and is used for keeping clock coherence among all modules, ensuring that the clocks among all units are homologous and in-phase, improving the precision of sequence scanning and improving the image quality.

The data analysis controller is realized by using a high-performance large-scale FPGA, and the number of the data analysis controllers can be one or more than one piece of FPGA. The data analysis controller analyzes the sequence scanning hardware control instruction transmitted by the special interface, distinguishes execution instruction types of different hardware, then respectively performs storage operation, issuing operation and configuration operation, and controls each functional circuit.

The functional circuit has the following three types:

the radio frequency transmitting circuit is used for generating a magnetic resonance radio frequency excitation signal and generating a control signal for controlling a rear-stage radio frequency amplifier, a radio frequency front end and other components. The radio frequency transmitting circuit can be composed of one group or a plurality of groups, and can realize multi-path parallel output of signals. The device in the radio frequency transmitting circuit receives the parameter configuration of the data analysis controller and works under the synchronous control of the data analysis controller and the synchronous clock. Each group of radio frequency transmitting circuits comprises an analog output interface and a digital output interface, and can be respectively adapted to different types of radio frequency amplifiers and radio frequency front ends.

The radio frequency transmitting circuit simulation interface part adopts the design of being compatible with various frequency filters, and can replace the simulation filters with different frequencies according to the practical application so as to be compatible with the magnetic resonance systems with different field strengths.

The gradient driving circuit can be composed of one or more groups of gradient driving circuits. The device has the functions of generating a plurality of paths of imaging gradient signals and shimming gradient signals and generating control signals of devices such as a gradient amplifier, a shimming amplifier and the like. The device in the gradient driving circuit receives the parameter configuration of the data analysis controller and works under the synchronous control of the data analysis controller and the synchronous clock. Each set of gradient driving circuit comprises a set of analog output interfaces of a plurality of paths and a set of digital output interfaces, and can be respectively adapted to different types of gradient amplifiers and shimming amplifiers.

The radio frequency receiving circuit is used for detecting a resonance signal of magnetic resonance, uploading the magnetic resonance digital signal to the data analysis controller after signal processing and analog-digital sampling, and uploading the magnetic resonance digital signal to a special computer for data post-processing and image display through the data analysis controller and the data communication unit. The radio frequency receiving circuit comprises a plurality of analog interfaces and a plurality of digital interfaces. The radio frequency receiving circuit receives the parameter configuration of the data analysis controller, and can also transmit the configuration parameters to the independent data receiving unit in parallel through the digital interface so as to control the multipath parallel work of the digital receiving unit. The multi-channel analog receiving channel of the radio frequency receiving circuit can directly process the analog magnetic resonance signal transmitted by the analog channel, and the digitized magnetic resonance signal is directly uploaded to the special computer through the data analysis controller and the data communication unit. Or the digital magnetic resonance data uploaded by the multi-channel parallel working data receiving unit can be uploaded to a special computer through a data analysis controller and a data communication unit, so that more magnetic resonance receiving channels are expanded and the parallel working of the multi-channel magnetic resonance receiving channels is ensured.

The multiple analog receiving channels can be configured according to different magnetic resonance receiving systems, and are preferably configured to be 4 or 8, and when the spectrometer is used for a low-field magnetic resonance imaging system or a magnetic resonance low-field spectrum and time domain spectrum system, the analog receiving channels are generally used for acquiring magnetic resonance signals.

The multi-channel analog receiving channel adopts the design of being compatible with filters with various frequencies, and the filters with different frequencies can be replaced according to practical application so as to be compatible with magnetic resonance systems with different field intensities.

As shown in fig. 4, the data receiving unit is composed of a dedicated interface, a controller and a plurality of analog receiving channels, and in this embodiment, 16 analog receiving channels are used, which can be matched with the analog receiving link of the existing market high-field magnetic resonance imaging system. Meanwhile, a plurality of data receiving units work in parallel, and the requirement of a high-end magnetic resonance imaging system on analog receiving links with more channels can be met. All analog receiving channels in the data receiving units working in parallel can realize random combination gating, and the application of different channel combination use in magnetic resonance clinic is met.

The special interface of the data receiving unit is connected with the digital interface in the data receiving circuit of the single board scanning control unit and is used for receiving the configuration instruction of the data receiving unit and sending the magnetic resonance data. The dedicated interface may be comprised of a high-speed serial digital fiber optic module of a custom protocol.

The analog receiving channel adopts the design of being compatible with filters with various frequencies, and the signal filters with different frequencies can be replaced according to practical application so as to be compatible with magnetic resonance systems with different field strengths.

The data receiving unit can be flexibly arranged in the magnetic resonance electromagnetic shielding room from the back of the magnetic resonance coil signal coupler to different positions of the electromagnetic shielding penetration plate so as to be matched with different types of magnetic resonance imaging systems. The following three mounting modes are listed in the embodiment of the invention. See in particular fig. 5-7.

The mode 1 can be installed at the inner side of a penetrating plate shielding room of a magnetic resonance electromagnetic shielding room, magnetic resonance analog signals are led out to the inner side of the penetrating plate through an analog line and connected to a data receiving unit, and the signals are digitized and then transmitted to a single-board scanning control unit through a waveguide tube of the penetrating plate through a special optical fiber of the data receiving unit.

The mode 2 can be installed beside the magnetic resonance magnet, magnetic resonance analog signals are led out beside the magnet through an analog line and are connected to the data receiving unit, and the signals are led out through a special optical fiber of the data receiving unit after being digitized and penetrate through a waveguide tube of the penetration plate to be sent to the single-board scanning control unit.

Mode 3. can be installed at the rear end of a receiving coil signal coupler on the examination bed, the magnetic resonance analog signal is directly connected to the data receiving unit from the receiving coil signal coupler, and the signal is digitalized and then led out through a special optical fiber of the data receiving unit to pass through a waveguide tube of the penetration plate and be sent to the single-board scanning control unit.

The technical scheme of the invention has the following beneficial effects:

the communication between each module of veneer scanning control unit passes through board level line connection, and the machining precision is high, connects stably, can not cause because of external force and environment scheduling problem to connect badly, can keep signal integrality to the at utmost, has improved the stability and the signal quality of spectrometer.

Each functional circuit of the single-board scanning control unit is provided with two interfaces, namely a digital interface and an analog interface, and can be adapted to different types of rear-stage power devices and analog receiving links.

The synchronous clock circuit connects the clock signal to each functional circuit of the single-board scanning control unit and the data communication unit and the data receiving unit thereof, thereby ensuring that the clocks among the units are in the same source and phase, improving the precision of sequence scanning and improving the image quality.

The interface of the data communication unit and the computer uses a common PCIe communication interface, has good compatibility and can be accessed to special computers with different functions.

The data receiving unit can work in parallel in multiple groups and can be gated by any channel combination.

By adopting an integrated and distributed spectrometer architecture, one set of spectrometer can be flexibly adapted to various magnetic resonance systems with different configurations and positions, and has extremely high compatibility.

Low-field magnetic resonance systems or low-field nuclear magnetic resonance spectroscopy systems for low-end positioning, for example: a 0.35T permanent magnet type magnetic resonance imaging system and a 0.7T superconducting type magnetic resonance imaging system. The data receiving unit can be connected to the user scanning host, and the analog radio frequency interface, the analog gradient interface and the analog receiving interface of the single-board scanning control unit are used for driving a power device and receiving magnetic resonance signals.

For high performance high field magnetic resonance imaging systems, such as 3.0T, 64 receive channel magnetic resonance imaging systems, a user operated computer is connected to a reconstruction computer. The data communication unit is integrated in the reconstruction computer, and a plurality of groups of analog or digital radio frequency interfaces and a plurality of groups of analog gradient interfaces of the single-board scanning control unit are used for driving the high-performance power component. The data receiving units working in parallel are arranged in the magnetic resonance electromagnetic shielding chamber and used for receiving the magnetic resonance signals. The technical scheme can support high-field multi-channel imaging application.

The foregoing detailed description of the preferred embodiments of the invention has been presented. It should be understood that numerous modifications and variations could be devised by those skilled in the art in light of the present teachings without departing from the inventive concepts. Therefore, the technical solutions available to those skilled in the art through logic analysis, reasoning and limited experiments based on the prior art according to the concept of the present invention should be within the scope of protection defined by the claims.

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