阅读说明：本技术 一种重症监护的辅助喂药装置 (Auxiliary medicine feeding device for intensive care therapy ) 是由 李暘 张凤 杜春艳 刘艳丽 张琪 于 2021-05-11 设计创作，主要内容包括：本发明涉及一种重症监护的辅助喂药装置。使用挤压结构结合胃管给昏迷患者实现用药,刺激性低,用药持久,方便；在挤压结构内设置有隔膜,从而实现在一次挤压中既可以进行药物的供给又可以利用挤压实现药物的混匀,精简了混匀的结构；设置光学检测装置,一方面检测药物的浓度,另一方面可以直接检测血液药物浓度,从而实现了给药的精确控制,提高给药精度；配合给药模型使用,可以精确的控制每次需要给药的量和浓度,从而可以实现保证血液药量在一定的范围内,适合重症患者使用。(The invention relates to an auxiliary medicine feeding device for intensive care. The extrusion structure is combined with the gastric tube to realize medication for the coma patient, so that the irritation is low, the medication is lasting and convenient; the diaphragm is arranged in the extrusion structure, so that the medicine can be supplied in one-time extrusion, the medicine can be uniformly mixed by extrusion, and the uniformly mixed structure is simplified; the optical detection device is arranged, so that the concentration of the medicine is detected on one hand, and the concentration of the blood medicine can be directly detected on the other hand, so that the accurate control of the medicine administration is realized, and the medicine administration accuracy is improved; the dosage and the concentration that need dose at every turn of control that the cooperation was dosed the model and is used to can be accurate to can realize guaranteeing that blood dose is in certain within range, be fit for severe patient and use.)

1. An auxiliary medicine feeding device for intensive care therapy comprises a controller, a mixing module, a concentration detection module, a blood detection module, a wireless transceiving module and a data analysis module; the method is characterized in that: the mixing module, the concentration detection module, the blood detection module, the wireless transceiver module and the data analysis module are connected to the controller;

the mixing module comprises a mixing cavity (1) for controlling the mixing of the liquid medicine and keeping the concentration of the medicine uniform;

the concentration detection module is used for detecting the concentration of the liquid medicine in the mixing module;

the blood detection module is used for detecting the concentration of the medicine in the blood;

the data analysis module is used for controlling the concentration of the medicine in the mixing module according to the concentration of the medicine in the blood, so that the concentration of the medicine in the blood is kept stable;

the wireless transceiver module is used for sending the monitoring data in the concentration detection module and the blood detection module to an upper computer and receiving a control instruction from the upper computer;

the data analysis module is pre-stored with a drug administration model, and the data analysis module inputs the data of the drug concentration in the blood detected by the blood detection module into the drug administration model to obtain the drug administration concentration and the drug administration amount which should be controlled currently.

2. The intensive care unit-feeding aid device according to claim 1, wherein:

the mixing module comprises a mixing cavity (1), an extrusion bag (2) and an extrusion head (3), and a medicine injection port and a nutrient solution injection port are connected above the mixing cavity (1), so that the medicine and the nutrient solution can enter the mixing cavity (1); the extrusion bag (2) is arranged below the mixing cavity (1) and connected with the mixing cavity (1), the medicine and the nutrient solution discharged from the mixing cavity (1) can enter the extrusion bag (2), and the stomach tube (4) is connected below the extrusion bag (2), so that the liquid in the extrusion bag (2) can enter the stomach tube (4);

extrusion heads (3) are arranged on two sides of the extrusion bag (2), and the extrusion heads (3) extrude the extrusion bag (2), so that the space inside the extrusion bag (2) is contracted and expanded; a plurality of diaphragm membranes (5) are arranged in the middle of the interior of the extrusion bag (2), and a one-way valve (6) is arranged at the bottom of the extrusion bag (2);

when the extrusion bag (2) is expanded, the diaphragms are separated from each other, so that the liquid in the mixing cavity (1) enters the extrusion bag (2), the liquid in the stomach tube (4) cannot flow back, and meanwhile the liquid at the upper part of the extrusion bag (2) enters the lower part of the extrusion bag (2);

when the extrusion bag (2) contracts, the diaphragm is contacted with each other, so that liquid below the extrusion bag (2) enters the stomach tube (4) through extrusion, the liquid above the extrusion bag (2) flows back to the mixing cavity (1) through extrusion, and the impact blending effect on the liquid in the mixing cavity (1) is realized through the extrusion effect.

3. The intensive care unit-feeding aid device according to claim 2, wherein:

the concentration detection module comprises a first light emitting head (7) and a first receiving head (8), the first light emitting head (7) and the first receiving head (8) are arranged on two sides of the mixing cavity (1), and light emitted from the first light emitting head (7) can be received by the first receiving head (8), so that the concentration of the corresponding medicine in the mixing cavity (1) can be obtained according to the intensity of the light with determined wavelength received by the first receiving head (8).

4. The intensive care unit-feeding aid device according to claim 1, wherein:

the blood detection module comprises a puncture needle, a pipeline (9), a second luminous head (10), a second receiving head (11) and a reflecting mirror surface (12); the puncture needle is connected with two sides of the pipeline (9) and is used for being inserted into a vein, so that blood can flow into the pipeline (9) from the puncture needle at one end and flow back to a blood vessel from the puncture needle at the other end;

the second light-emitting head (10) and the second receiving head (11) are arranged on one side of the pipeline (9), a cylindrical reflecting mirror surface (12) is arranged at a corresponding position, and the reflecting mirror surface (12) wraps the pipeline (9), so that light can undergo multiple reflections inside the pipeline (9); the reflecting mirror surface (12) is provided with a hole for allowing the light of the second light-emitting head (10) and the second receiving head (11) to enter and exit; the light emitted by the second light-emitting head (10) enters the reflecting mirror surface (12), is reflected for multiple times in the light and then is emitted to the second receiving head (11), and the second receiving head (11) can obtain the concentration of the corresponding medicine in the blood according to the intensity of the received light with the determined wavelength.

5. The intensive care unit-feeding aid device according to claim 1, wherein:

the parameters of the administration model comprise administration concentration C, administration amount M, delay time T, absorption rate A and blood drug concentration D, and specifically comprise:

D=f(M,C,T,A)

that is, the blood drug concentration is a function of the administration concentration C, the administration amount M, the delay time T and the absorption rate A, wherein the delay time T and the absorption rate A are related to the individual drug, T is the peak time of single administration, the administration concentration is the concentration of the drug in the liquid medicine, and the administration amount is the administration volume;

according to a drug-time curve in pharmacokinetics, the concentration of a drug in blood after single administration is increased firstly and then reduced, and in order to ensure that the concentration of the drug in blood is kept above an effective concentration and below a minimum toxic concentration, the drug needs to be administered for the second time in advance before the drug reaches the minimum effective concentration;

the drug-time curve of the second administration is calculated in advance for a certain time when the second administration is carried out, and both the second administration time and T, A are fixed values, so that the drug-time curve of the second administration can be obtained by adjusting the drug concentration C and the administration amount M in the data analysis module, then the drug-time curve of the second administration and the drug-time curve of the previous administration are superposed in time and concentration, and when the blood drug concentration is kept above the effective concentration and below the lowest toxic concentration, the second administration time, the administration concentration C and the administration amount M can be determined;

a third dose is then administered, and the drug-time curve for the third dose is superimposed with the drug-time curves for the first two doses over time and concentration, and so on.

6. The intensive care unit as recited in claim 4, wherein:

the pipeline (9) is made of quartz glass.

Technical Field

The invention relates to the field of medical instruments, in particular to an auxiliary medicine feeding device for intensive care.

Background

Intensive care (intensive care) refers to the intensive treatment and nursing of various critical patients by applying various advanced medical technologies and modern monitoring and rescuing equipment. To ensure the survival and the subsequent life quality of the patient to the maximum extent.

Patients in intensive care units are generally in a coma or semi-coma state, which has great influence on the medicine feeding of the patients in the state; general intensive care does not allow family members to visit for a long time, but nurses are difficult to feed medicines beside a bed for a long time; moreover, most of severe patients are inserted with stomach tubes, the administration time is long, and the patients can be injured by carelessness.

Application number CN202010896766.8 discloses an intensive care therapy medicine feed ware, including medicine feed ware main part, connecting piece and the solid fixed ring of forefinger, the medicine feed ware main part comprises conveyor, liquid medicine storage device and medicine feed ware base, and the embedding has controlling means in the conveyor, and controlling means includes singlechip and button cell, and simple structure, with low costs, but still need artifical cooperation to use.

Application number CN202010936506.9 discloses an intelligent medicine feeding system for clinical care of an intensive care department, which comprises a workbench, a medicine crushing device and a transfusion device, wherein a medicine storage box is arranged on the workbench, the bottom of the medicine storage box is communicated with a conduit, and an electromagnetic valve is arranged on the conduit and controls the opening and closing of the conduit; the medicine crushing device comprises a box body fixedly connected to the workbench and a driving piece fixedly connected to the workbench, the guide pipe is communicated with the box body, the driving piece is fixedly connected to the box body, an output shaft of the driving piece extends into the box body and is fixedly connected with a pressing block, and the side wall of the pressing block is abutted against the inner wall of the box body; its function is only for breaking and feeding medicine, and the condition of the medicine cannot be continuously monitored.

Disclosure of Invention

In view of the above, in order to solve the above problems, an auxiliary medicine feeding device for intensive care therapy includes a controller, a mixing module, a concentration detection module, a blood detection module, a wireless transceiver module, and a data analysis module; the mixing module, the concentration detection module, the blood detection module, the wireless transceiver module and the data analysis module are connected to the controller;

the mixing module comprises a mixing cavity for controlling the mixing of the liquid medicine and keeping the concentration of the medicine uniform;

the concentration detection module is used for detecting the concentration of the liquid medicine in the mixing module;

the blood detection module is used for detecting the concentration of the medicine in the blood;

the data analysis module is used for controlling the concentration of the medicine in the mixing module according to the concentration of the medicine in the blood, so that the concentration of the medicine in the blood is kept stable;

the wireless transceiver module is used for sending the monitoring data in the concentration detection module and the blood detection module to an upper computer and receiving a control instruction from the upper computer;

the data analysis module is pre-stored with a drug administration model, and the data analysis module inputs the data of the drug concentration in the blood detected by the blood detection module into the drug administration model to obtain the drug administration concentration and the drug administration amount which should be controlled currently.

The mixing module comprises a mixing cavity, an extrusion bag and an extrusion head, and a medicine injection port and a nutrient solution injection port are connected above the mixing cavity, so that the medicine and the nutrient solution can enter the mixing cavity; the extrusion bag is arranged below the mixing cavity and connected with the mixing cavity, the medicine and the nutrient solution discharged from the mixing cavity can enter the extrusion bag, and the stomach tube is connected below the extrusion bag, so that the liquid in the extrusion bag can enter the stomach tube;

the two sides of the extrusion bag are provided with extrusion heads which extrude the extrusion bag, so that the space inside the extrusion bag is contracted and expanded; a plurality of diaphragm membranes are arranged in the middle of the interior of the extrusion bag, and a one-way valve is arranged at the bottom of the extrusion bag;

when the squeezing bag expands, the diaphragms are separated from each other, so that liquid in the mixing cavity enters the squeezing bag, the liquid in the stomach tube cannot flow back, and meanwhile, the liquid on the upper part of the squeezing bag enters the lower part of the squeezing bag;

when the extrusion bag contracts, the diaphragms are in contact with each other, so that liquid below the extrusion bag enters the stomach tube through extrusion, the liquid above the extrusion bag returns to the mixing cavity through extrusion, and the liquid in the mixing cavity is impacted and uniformly mixed due to the extrusion effect.

The concentration detection module comprises a first light emitting head and a first receiving head, the first light emitting head and the first receiving head are arranged on two sides of the mixing cavity, light emitted from the first light emitting head can be received by the first receiving head, and therefore the concentration of the corresponding medicine in the mixing cavity can be obtained according to the intensity of the light with the determined wavelength received by the first receiving head.

The blood detection module comprises a puncture needle, a pipeline, a second light-emitting head, a second receiving head and a reflecting mirror surface; the puncture needle is connected with two sides of the pipeline and is used for being inserted into a vein, so that blood can flow into the pipeline from the puncture needle at one end and flow back to a blood vessel from the puncture needle at the other end;

the second light-emitting head and the second receiving head are arranged on one side of the pipeline, a cylindrical reflecting mirror surface is arranged at the corresponding position, and the reflecting mirror surface wraps the pipeline, so that light can undergo multiple reflections inside the pipeline; the reflecting mirror surface is provided with a hole for allowing the light of the second light-emitting head and the second receiving head to enter and exit; the light emitted by the second light-emitting head enters the reflecting mirror surface, is reflected for multiple times inside the reflecting mirror surface and then is emitted to the second receiving head, and the second receiving head can obtain the concentration of the corresponding medicine in the blood according to the intensity of the received light with the determined wavelength.

The parameters of the administration model comprise administration concentration C, administration amount M, delay time T, absorption rate A and blood drug concentration D, and specifically comprise:

D=f(M,C,T,A)

that is, the blood drug concentration is a function of the administration concentration C, the administration amount M, the delay time T and the absorption rate A, wherein the delay time T and the absorption rate A are related to the individual drug, T is the peak time of single administration, the administration concentration is the concentration of the drug in the liquid medicine, and the administration amount is the administration volume;

according to a drug-time curve in pharmacokinetics, the concentration of a drug in blood after single administration is increased firstly and then reduced, and in order to ensure that the concentration of the drug in blood is kept above an effective concentration and below a minimum toxic concentration, the drug needs to be administered for the second time in advance before the drug reaches the minimum effective concentration;

the drug-time curve of the second administration is calculated in advance for a certain time when the second administration is carried out, and both the second administration time and T, A are fixed values, so that the drug-time curve of the second administration can be obtained by adjusting the drug concentration C and the administration amount M in the data analysis module, then the drug-time curve of the second administration and the drug-time curve of the previous administration are superposed in time and concentration, and when the blood drug concentration is kept above the effective concentration and below the lowest toxic concentration, the second administration time, the administration concentration C and the administration amount M can be determined;

a third dose is then administered, and the drug-time curve for the third dose is superimposed with the drug-time curves for the first two doses over time and concentration, and so on.

The pipeline is made of quartz glass.

The invention has the beneficial effects that:

the medicine is taken by the coma patient by combining the extrusion structure with the stomach tube, so that the stimulation is low, the medicine taking is lasting and convenient;

the diaphragm is arranged in the extrusion structure, so that the medicine can be supplied in one-time extrusion, the medicine can be uniformly mixed by extrusion, and the uniformly mixed structure is simplified;

the optical detection device is arranged, so that the concentration of the medicine is detected on one hand, and the concentration of the blood medicine can be directly detected on the other hand, so that the accurate control of the medicine administration is realized, and the medicine administration accuracy is improved; the dosage and the concentration that need dose at every turn of control that the cooperation was dosed the model and is used to can be accurate to can realize guaranteeing that blood dose is in certain within range, be fit for severe patient and use.

Drawings

The accompanying drawings, which are included to provide a further understanding of the disclosed subject matter, are incorporated in and constitute a part of this specification. The drawings illustrate the implementations of the disclosed subject matter and, together with the detailed description, serve to explain the principles of implementations of the disclosed subject matter. No attempt is made to show structural details of the disclosed subject matter in more detail than is necessary for a fundamental understanding of the disclosed subject matter and various modes of practicing the same.

FIG. 1 is a schematic view of the overall structure of the present invention;

FIG. 2 is a schematic diagram of the mixing module and the concentration detection module according to the present invention;

fig. 3 is a schematic structural diagram of the blood detection module of the present invention.

Detailed Description

The advantages, features and methods of accomplishing the same will become apparent from the drawings and the detailed description that follows.

An auxiliary medicine feeding device for intensive care therapy comprises a controller, a mixing module, a concentration detection module, a blood detection module, a wireless transceiving module and a data analysis module; the mixing module, the concentration detection module, the blood detection module, the wireless transceiver module and the data analysis module are connected to the controller;

the mixing module comprises a mixing cavity 1 for controlling the mixing of the liquid medicine and keeping the concentration of the medicine uniform;

the concentration detection module is used for detecting the concentration of the liquid medicine in the mixing module;

the blood detection module is used for detecting the concentration of the medicine in the blood;

the data analysis module is used for controlling the concentration of the medicine in the mixing module according to the concentration of the medicine in the blood, so that the concentration of the medicine in the blood is kept stable;

the wireless transceiver module is used for sending the monitoring data in the concentration detection module and the blood detection module to an upper computer and receiving a control instruction from the upper computer;

the data analysis module is pre-stored with a drug administration model, and the data analysis module inputs the data of the drug concentration in the blood detected by the blood detection module into the drug administration model to obtain the drug administration concentration and the drug administration amount which should be controlled currently.

The mixing module comprises a mixing cavity 1, an extrusion bag 2 and an extrusion head 3, and a medicine injection port and a nutrient solution injection port are connected above the mixing cavity 1, so that the medicine and the nutrient solution can enter the mixing cavity 1; the extrusion bag 2 is arranged below the mixing cavity 1 and connected with the mixing cavity 1, medicine and nutrient solution discharged from the mixing cavity 1 can enter the extrusion bag 2, and a stomach tube 4 is connected below the extrusion bag 2, so that the liquid in the extrusion bag 2 can enter the stomach tube 4;

the two sides of the extrusion bag 2 are provided with extrusion heads 3, and the extrusion heads 3 extrude the extrusion bag 2, so that the space inside the extrusion bag 2 is contracted and expanded; a plurality of diaphragm membranes 5 are arranged in the middle of the interior of the extrusion bag 2, and a one-way valve 6 is arranged at the bottom of the extrusion bag 2;

when the extrusion bag 2 is expanded, the diaphragms are separated from each other, so that the liquid in the mixing cavity 1 enters the extrusion bag 2, the liquid in the stomach tube 4 cannot flow back, and meanwhile, the liquid on the upper part of the extrusion bag 2 enters the lower part of the extrusion bag 2;

when the squeeze bag 2 contracts, the diaphragms are in contact with each other, so that liquid below the squeeze bag 2 enters the stomach tube 4 through squeezing, the liquid above the squeeze bag 2 returns to the mixing cavity 1 through squeezing, and the liquid in the mixing cavity 1 is impacted and uniformly mixed due to the squeezing effect.

The concentration detection module comprises a first light emitting head 7 and a first receiving head 8, the first light emitting head 7 and the first receiving head 8 are arranged on two sides of the mixing cavity 1, and light emitted from the first light emitting head 7 can be received by the first receiving head 8, so that the concentration of the corresponding medicine in the mixing cavity 1 can be obtained according to the intensity of the light with determined wavelength received by the first receiving head 8.

The blood detection module comprises a puncture needle, a pipeline 9, a second luminous head 10, a second receiving head 11 and a reflecting mirror surface 12; the tube 9 is connected on both sides with a needle for insertion into a vein, so that blood can flow from the needle at one end into the tube 9 and from the needle at the other end back into the blood vessel;

the second light emitting head 10 and the second receiving head 11 are arranged at one side of the pipeline 9, a cylindrical reflecting mirror surface 12 is arranged at the corresponding position, and the reflecting mirror surface 12 wraps the pipeline 9, so that the light can undergo multiple reflections inside the pipeline 9; the reflecting mirror surface 12 is provided with a hole for allowing the light of the second light-emitting head 10 and the second receiving head 11 to enter and exit; the light emitted by the second light emitting head 10 enters the reflecting mirror 12, and is reflected for multiple times inside the light and then emitted to the second receiving head 11, and the second receiving head 11 can obtain the concentration of the corresponding drug in the blood according to the intensity of the received light with the determined wavelength.

The parameters of the administration model comprise administration concentration C, administration amount M, delay time T, absorption rate A and blood drug concentration D, and specifically comprise:

D=f(M,C,T,A)

that is, the blood drug concentration is a function of the administration concentration C, the administration amount M, the delay time T and the absorption rate A, wherein the delay time T and the absorption rate A are related to the individual drug, T is the peak time of single administration, the administration concentration is the concentration of the drug in the liquid medicine, and the administration amount is the administration volume;

according to a drug-time curve in pharmacokinetics, the concentration of a drug in blood after single administration is increased firstly and then reduced, and in order to ensure that the concentration of the drug in blood is kept above an effective concentration and below a minimum toxic concentration, the drug needs to be administered for the second time in advance before the drug reaches the minimum effective concentration;

the drug-time curve of the second administration is calculated in advance for a certain time when the second administration is carried out, and both the second administration time and T, A are fixed values, so that the drug-time curve of the second administration can be obtained by adjusting the drug concentration C and the administration amount M in the data analysis module, then the drug-time curve of the second administration and the drug-time curve of the previous administration are superposed in time and concentration, and when the blood drug concentration is kept above the effective concentration and below the lowest toxic concentration, the second administration time, the administration concentration C and the administration amount M can be determined;

a third dose is then administered, and the drug-time curve for the third dose is superimposed with the drug-time curves for the first two doses over time and concentration, and so on.

The material of the pipeline 9 is quartz glass. The volume of the extrusion bag is determined, so that the dosage can be controlled by controlling the extrusion times, when the concentration detection module cannot detect the medicine (the strength of the first receiving head is higher than a certain threshold value), the fact that the residual quantity of the medicine is low is indicated, the extrusion can be stopped by the extrusion times, and the medicine feeding process is completed.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.