阅读说明：本技术 氨磺酰基-芳基酰胺和其作为药物用于治疗乙型肝炎的用途 (Sulfamoyl-arylamides and their use as medicaments for the treatment of hepatitis B ) 是由 S.J.拉斯特 P.J-M.B.拉博伊斯森 G.罗姆博特斯 K.范德克 W.G.维斯楚伊伦 于 2013-08-28 设计创作，主要内容包括：本发明涉及氨磺酰基-芳基酰胺和其作为药物用于治疗乙型肝炎的用途。涉及具有化学式(I)的HBV复制抑制剂包括其立体化学同分异构形式,以及盐、水合物、溶剂化物,其中B、R-1、R-2和R-4具有如在此定义的含义。本发明还涉及包含这些抑制剂的药物组合物以及在HBV疗法中它们单独的或与其他HBV抑制剂组合的用途。(The present invention relates to sulfamoyl-arylamides and their use as medicaments for the treatment of hepatitis b. Relates to inhibitors of HBV replication of formula (I) Including stereochemically isomeric forms thereof, and salts, hydrates, solvates thereof, wherein B, R 1 、R 2 And R 4 Have the meaning as defined herein. The invention also relates to pharmaceutical compositions comprising these inhibitors and their use alone or in combination with other HBV inhibitors in HBV therapy.)