阅读说明：本技术 一种低冰点次氯酸消毒液及其制备方法 (Low-freezing-point hypochlorous acid disinfectant and preparation method thereof ) 是由 王英男 韩建春 董春雨 王英鹏 刘丽 吴春梅 廉光福 李仁杰 吴蔓绮 王禹然 于 2021-02-01 设计创作，主要内容包括：本发明消毒液制造技术领域,目的是提供一种低冰点次氯酸消毒液,不仅可以促进次氯酸的稳定性,可以安全使用、又符合特殊低温环境-30℃冰点的极限环境要求。制备所述消毒液的原料包括5-100g/L的氯化钠、450-700g/L纯化水、5-400g/L食品级丙二醇和5-400g/L食品级丙三醇。本发明不仅能在冰点在-30℃,杀菌率达到99.99％,更能全面对低温环境及物品进行消杀,对现场使用的设备、工作人员均无害。同时,能提高工作效率和更好的控制、节省成本。(The invention belongs to the technical field of disinfectant preparation, and aims to provide a hypochlorous acid disinfectant with a low freezing point, which can promote the stability of hypochlorous acid, can be safely used and meets the requirement of a special low-temperature environment on a limiting environment with a freezing point of-30 ℃. The raw materials for preparing the disinfectant comprise 5-100g/L of sodium chloride, 450-700g/L of purified water, 5-400g/L of food-grade propylene glycol and 5-400g/L of food-grade glycerol. The invention can not only sterilize at the freezing point of-30 ℃ and the sterilizing rate of 99.99 percent, but also comprehensively sterilize low-temperature environment and articles, and has no harm to equipment and workers used on site. Meanwhile, the working efficiency can be improved, the control is better, and the cost is saved.)

1. A hypochlorous acid disinfectant with low freezing point is characterized in that: the raw materials for preparing the disinfectant comprise 5-100g/L of sodium chloride, 450-700g/L of purified water, 5-400g/L of food-grade propylene glycol and 5-400g/L of food-grade glycerol.

2. A preparation method of hypochlorous acid disinfectant with a low freezing point is characterized by comprising the following steps: the method comprises the following steps:

(1) mixing food-grade propylene glycol and glycerol at normal temperature, uniformly stirring in a high-speed stirring tank, and putting into a premixing tank for later use;

(2) putting the sodium chloride into a high-speed stirring tank according to the proportion, adding purified water, and uniformly stirring until the sodium chloride is completely dissolved;

(3) adding the mixed materials obtained in the step (2) into an oxidation potential electrolysis unit to be electrolyzed to generate hypochlorous acid electrolyzed water;

the oxidation potential electrolysis unit has the effective chlorine of 500-800mg/L and the PH of 5.0-8.5;

(4) adding hypochlorous acid electrolyzed water in the step (3) into the premixing tank in the step (1) and uniformly stirring at a high speed;

(5) and (5) filling, packaging and sealing to obtain a finished product.

3. The low freezing point hypochlorous acid disinfectant of claim 1, wherein: the raw materials for preparing the disinfectant are as follows: the raw materials for preparing the disinfectant comprise 30-60g/L of sodium chloride, 400-500g/L of purified water, 200-300g/L of food-grade propylene glycol and 200-300g/L of food-grade glycerol.

4. The low freezing point hypochlorous acid disinfectant of claim 3, wherein: the raw materials for preparing the disinfectant are as follows: 50g/L of sodium chloride, 450g/L of purified water, 270g/L of food-grade propylene glycol and 280g/L of food-grade glycerol.

Technical Field

The invention belongs to the technical field of disinfectant preparation, and particularly relates to a hypochlorous acid disinfectant with a low freezing point and a preparation method thereof.

Background

The conventional sterilization method is mainly based on a heat sterilization/degerming method, but the chemical mainly uses chlorine-series bactericides such as sodium chlorite, enzyme-series bactericides such as hydrogen peroxide and ozone, and alcohol. However, they are not universal, and require attention in many respects such as energy cost, mixing of drugs into products, worker and environmental impact, and the methods of use and places of use are also limited, and therefore they are used according to their respective characteristics. The following list illustrates the adverse effects of the disinfecting solutions described in the guidelines:

1. peroxyacetic acid:

it is mentioned in the "hospital sterilization specifications" (second edition) that peracetic acid is unstable, easily decomposed, highly corrosive, and harmful to consumer products. Since low-concentration peracetic acid is more unstable, it should be used as it is, and therefore, high-concentration peracetic acid which is used as it is commercially available. The corrosion of the peroxyacetic acid which is used for killing the bacteria for a long time can cause huge damage to human bodies. Therefore, protective tools need to be worn during the process of using the peroxyacetic acid for a long time.

2. Hydrogen peroxide:

in the hospital disinfection specifications (second edition) it is stated that less than 3% hydrogen peroxide is non-irritating to the skin, but the guidelines describe the use of 6% hydrogen peroxide, which can be harmful to personnel during use.

3. Quaternary ammonium salt disinfectant:

in the technical manual of the new coronavirus prevention and control disinfection in the cold chain food production and operation process, quaternary ammonium salt disinfectants can remain on equipment for a long time, so that the disinfectants need to be thoroughly washed and removed by water after use. From this point it appears that after the quaternary disinfectant has been used, a second rinse is required. In the technical Specification for Hospital Disinfection (second edition), it is stated that single-chain quaternary disinfectants, which are highly affected by organic substances and are relatively expensive, can cause resistance to viruses and bacteria.

In addition to the disinfectants described in the guidelines, many people on the market now use other disinfectants for the outer surface of cold chain food products, but these are harmful to the human body and to the sterilized goods.

In the recent television news, a large company plant reported uses ozone in cold chain food sterilization tunnels, indicating that the use of ozone avoids the problem of chlorine-containing disinfectants remaining. However, ozone is unstable and harmful to human body, and the allowed concentration of ozone in the atmosphere is 0.2mg/m according to national regulations³In the case of a human, the indoor allowable concentration is 0.16mg/m³Generally, the concentration required for disinfection operation is above the concentration required (the use method proposed in the technical specification of hospital disinfection (second edition)), and in places with relatively dense personnel, such as the cold chain industry, improper operation easily causes accidents, and ozone itself has strong corrosiveness.

Sodium hypochlorite (84 disinfectant) and chlorine dioxide which are commonly used in chlorine-containing disinfectants cannot be sprayed or atomized into the air, but the distinction among the sodium hypochlorite, the chlorine dioxide and the hypochlorous acid is difficult to distinguish on site, so that the chlorine-containing disinfectants are thought to be cut with one's knife'. The chlorine-containing disinfectant can be completely controlled by popularizing a simple detection means on the site. In the second edition of the hospital disinfection technical Specification, hypochlorous acid is classified as a brand-new generation of high-efficiency disinfectant, has no residue after use, and is a completely harmless and nontoxic environment-friendly disinfectant. The hypochlorous acid is non-corrosive, non-combustible and non-explosive, is safe and environment-friendly, and can not cause drug resistance to bacteria and viruses after being used for a long time. Although hypochlorous acid is currently ruled out in chlorine-containing disinfectants in China, many characteristics of the hypochlorous acid are far superior to those of the chlorine-containing disinfectants. Hypochlorous acid can rapidly pass through virus cell membranes, bacterial cell walls and shells of spores, enters the virus cell membranes, destroys RNA or DNA, inactivates the RNA or DNA, and realizes instant inactivation.

In summary, the disinfection products applied to different aspects such as food, medicine, human skin, article surface, environment and the like at present have no corrosiveness, are non-inflammable and non-explosive, are safe and environment-friendly, can be used for a long time, have a freezing point of-30 ℃, and do not cause drug resistance to bacteria and viruses. The conventional hypochlorous acid disinfectant has a high freezing point close to 0 ℃, and has limitations on transportation, use and storage conditions in winter in the north.

Disclosure of Invention

The invention provides a hypochlorous acid disinfectant with a low freezing point and a preparation method thereof, aiming at promoting the stability of hypochlorous acid, being safe to use and meeting the requirement of a special low-temperature environment on a limiting environment with a freezing point of-30 ℃.

In order to achieve the purpose, the invention adopts the technical scheme that:

a hypochlorous acid disinfectant with a low freezing point is prepared from 5-100g/L sodium chloride, 450-700g/L purified water, 5-400g/L food-grade propylene glycol and 5-400g/L food-grade glycerol.

The preparation method comprises the following steps:

(1) mixing food-grade propylene glycol and glycerol at normal temperature, uniformly stirring in a high-speed stirring tank, and putting into a premixing tank for later use;

(2) putting the sodium chloride into a high-speed stirring tank according to the proportion, adding purified water, and uniformly stirring until the sodium chloride is completely dissolved;

(3) adding the mixed materials obtained in the step (2) into an oxidation potential electrolysis unit to be electrolyzed to generate hypochlorous acid electrolyzed water;

the oxidation potential electrolysis unit adopts a diaphragm-free electrolytic cell, the available chlorine of the unit is 500-800mg/L, and the PH is 5.0-8.5;

(4) adding hypochlorous acid electrolyzed water in the step (3) into the premixing tank in the step (1) and uniformly stirring at a high speed;

(5) and (5) filling, packaging and sealing to obtain a finished product.

Further, the raw materials for preparing the disinfectant are as follows: the raw materials for preparing the disinfectant comprise 30-60g/L of sodium chloride, 400-500g/L of purified water, 200-300g/L of food-grade propylene glycol and 200-300g/L of food-grade glycerol.

Further, the raw materials for preparing the disinfectant are as follows: 50g/L of sodium chloride, 450g/L of purified water, 270g/L of food-grade propylene glycol and 280g/L of food-grade glycerol.

Compared with the prior art, the invention has the following beneficial effects:

1. the invention takes sodium chloride as a main material, and various auxiliary materials are added to interact, so that the effective sterilization rate can reach 99.99 percent, and the invention also meets the limit environmental requirement of a special low-temperature environment with a freezing point of-30 ℃.

2. According to the invention, through the addition and scientific compatibility of two nonpolar alcohols of food-grade propylene glycol and glycerol, the stability of hypochlorous acid can be promoted, and the sterilization time and the sterilization effect of hypochlorous acid disinfectant on the surface of an object can be prolonged.

3. The hypochlorous acid disinfectant disclosed by the invention uses a diaphragm-free electrolytic tank, salt and purified water are used as raw materials, the yield of the unit is 100L/h, the available chlorine is 500-800mg/L, the PH is 5.0-8.5, and the weakly acidic and neutral electrolytic functional water obtained by electric decomposition can be safely used.

4. The invention can not only sterilize at the freezing point of-30 ℃ and the sterilizing rate of 99.99 percent, but also comprehensively sterilize low-temperature environment and articles, and has no harm to equipment and workers used on site. Meanwhile, the working efficiency can be improved, the control is better, and the cost is saved.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Example 1:

a hypochlorous acid disinfectant with low freezing point and a preparation method thereof, which comprises the following steps,

(1) weighing 20kg of food-grade propylene glycol and 15kg of glycerol at about 20 ℃, mixing in proportion, putting into a high-speed stirring tank, stirring uniformly, and putting into a premixing tank for later use;

(2) putting 200g of sodium chloride into a high-speed stirring tank, adding purified water, and uniformly stirring until the sodium chloride is completely dissolved;

(3) adding the mixed material obtained in the step (2) into an oxidation potential electrolysis machine to electrolyze to generate 100L of hypochlorous acid water; the oxidation potential electrolyzer unit adopts a diaphragm-free type electrolyzer, and the output of the unit is 100L/h, the available chlorine is 500mg/L, and the PH value is 5.0-8.5.

(4) Adding hypochlorous acid electrolyzed water in the step (3) into the premixing tank in the step (1) and uniformly stirring at a high speed;

(5) filling into a 5L opaque food-grade plastic barrel, and sealing by magnetic induction;

example 2:

a hypochlorous acid disinfectant with low freezing point and a preparation method thereof, which comprises the following steps,

(1) weighing 30kg of food-grade propylene glycol and 55kg of glycerol at about 20 ℃, proportionally mixing, and uniformly stirring in a high-speed stirring tank; putting the mixture into a premixing tank for later use;

(2) putting 250g of sodium chloride into a high-speed stirring tank, adding purified water, and uniformly stirring until the sodium chloride is completely dissolved;

(3) adding the mixed material obtained in the step (2) into an oxidation potential electrolysis machine to electrolyze to generate 100L of hypochlorous acid water; the oxidation potential electrolyzer unit adopts a diaphragm-free type electrolyzer, and the output of the unit is 100L/h, the available chlorine is 700mg/L, and the PH value is 5.0-8.5.

(4) Adding hypochlorous acid electrolyzed water in the step (3) into the premixing tank in the step (1) and uniformly stirring at a high speed;

(5) filling into a 5L opaque food-grade plastic barrel, and sealing by magnetic induction;

example 3:

a hypochlorous acid disinfectant with low freezing point and a preparation method thereof, which comprises the following steps,

(1) weighing 10kg of food-grade propylene glycol and 30kg of glycerol at about 20 ℃, mixing in proportion, putting into a high-speed stirring tank, stirring uniformly, and putting into a premixing tank for later use;

(2) putting 300g of sodium chloride into a high-speed stirring tank, adding purified water, and uniformly stirring until the sodium chloride is completely dissolved;

(3) adding the mixed material obtained in the step (2) into an oxidation potential electrolysis machine to electrolyze to generate 100L of hypochlorous acid water; the oxidation potential electrolyzer unit adopts a diaphragm-free type electrolyzer, and the output of the unit is 100L/h, the available chlorine is 800mg/L, and the PH value is 5.0-8.5.

(4) Adding hypochlorous acid electrolyzed water in the step (3) into the premixing tank in the step (1) and uniformly stirring at a high speed;

(5) filling into a 5L opaque food-grade plastic barrel, and sealing by magnetic induction;

the invention takes sodium chloride as a main material, and various auxiliary materials are added to interact, so that the effective sterilization rate can reach 99.99 percent, and the invention also meets the limit environmental requirement of a special low-temperature environment with a freezing point of-30 ℃.

Firstly, the invention can not only promote the stability of hypochlorous acid, but also prolong the sterilization time and sterilization effect of hypochlorous acid disinfectant on the surface of an object by adding two nonpolar alcohols of food-grade propylene glycol and glycerol and scientifically proportioning. Secondly, the hypochlorous acid disinfectant of the invention uses a diaphragm-free electrolytic tank, salt and purified water are used as raw materials, the output of the unit is 100L/h, the available chlorine is 500-800mg/L, the PH is 5.0-8.5, and the weakly acidic and neutral electrolytic functional water obtained by electric decomposition can be safely used. The sterilization rate can reach 99.99 percent at the freezing point of-30 ℃, can comprehensively sterilize and kill low-temperature environment and articles, and is harmless to field equipment and workers. Meanwhile, the working efficiency can be improved, the control is better, and the cost is saved.

The following is a comparative table of the low temperature test data of the present invention:

the preferred embodiments of the invention disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.